Intelligent Medicine with Dr. Ronald Hoffman | The Best of High Tech Medicine and Alternative Modalities

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Intelligent Medicine Radio for July 18, Part 1: Preserving Brain Function Jul 20, 2026

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Diets rich in fruits and vegetables preserve brain function—but in vulnerable persons with the ApoE4 “Alzheimer’s gene”, more meat staves off decline, contradicting years of recommendations to minimize animal protein; Supplements for adrenal insufficiency; “Forever chemicals” may weaken teen’s bones—but menopausal hormone replacement therapy decisively fends off osteoporosis; Legionnaire's disease strikes poor and affluent alike in New York City; Doctors propose warning labels for GLP-1 drugs on account of this under-appreciated danger.

Intelligent Medicine Radio for July 18, Part 2: Testosterone Screening for Troops Jul 20, 2026

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Pentagon plans widespread testosterone screening for troops; New study claims arthroscopic surgery for age-related degenerative changes of knees is worthless; Widely touted “precision” proton therapy doesn’t outperform conventional radiation treatment for prostate cancer; Comparing the effectiveness of gummies and liquids vs. tablet or capsule forms of supplements; Supplements to lower LDL; Lithium orotate for Alzheimer’s prevention; Novel ultrasound treatment may target inflammation in osteoarthritis; Researchers explore antiviral treatments for multiple sclerosis.

Leyla Weighs In: The Hidden Impact of B12 Deficiency on Aging Jul 17, 2026

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Vitamin B12 Deficiency--The “Aging” Symptoms You Shouldn’t Ignore: Leyla Muedin, a registered dietitian nutritionist in New York City, discusses vitamin B12 deficiency as a common problem that can mimic normal aging, noting adults need only about two micrograms daily to support red blood cells, nerves, and DNA. She reviews the history of liver treatment for pernicious anemia and explains that deficiency remains common in older adults, vegans/vegetarians, and people with impaired absorption due to low stomach acid, autoimmune gastritis, weight loss surgery, or medications such as metformin and proton pump inhibitors. Symptoms can develop slowly and include fatigue, weakness, shortness of breath, numbness/tingling, poor balance, memory issues, and brain fog; she advises medical evaluation and B12 testing rather than assuming aging or relying on wellness-clinic injections when levels are normal. She emphasizes B12 is primarily in animal foods, so vegans need supplements, and notes broader nutrient shortfalls she sees in vegan clients.

Q&A with Leyla, Part 1: Aortic Dissection Jul 16, 2026

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Does coffee really dehydrate you? A deeper dive on this important topic
Help for nighttime urination
Please discuss aortic dissection

Q&A with Leyla, Part 2: Mushroom Coffee Jul 16, 2026

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How do I find a preventive cardiologist in northern New Jersey?
What is the best supplement for dissolving bone spurs?
What is the half-life of vitamin D, either by supplement or sun exposure?
What do you think about mushroom coffee? Does it have any health benefits?
Please discuss how strontium affects DEXA scan results

Vagus Nerve Stimulation for Rheumatoid Arthritis and Beyond, Part 1 Jul 15, 2026

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Dr. David Chernoff, Chief Medical Officer of Setpoint Medical, discusses electrically driven vagus nerve stimulation (VNS) as a “neuroimmune modulation” approach to autoimmune and inflammatory disease. Chernoff explains the vagus nerve’s sensory role in monitoring organs and signaling the brainstem and spleen to regulate immune responses, and how precise stimulation can reduce pro-inflammatory cytokines without immunosuppression. Setpoint’s miniaturized, wireless, MRI-compatible implant is placed in an outpatient 45-minute neck procedure and delivers one minute of daily stimulation titrated to an upper comfort level; long-term safety is supported by prior surgical experience and a 242-patient blinded RA study with two-year data, leading to FDA approval for rheumatoid arthritis. The discussion covers add-on use with medications, potential steroid tapering, reimbursement, and research in Crohn’s disease, relapsing MS (vision and remyelination), and other conditions, including psoriatic arthritis, lupus, and neurodegenerative diseases.

Vagus Nerve Stimulation for Rheumatoid Arthritis and Beyond, Part 2 Jul 15, 2026

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Dr. Hoffman continues his conversation with Dr. David Chernoff, Chief Medical Officer of Setpoint Medical.

Unlocking the Power of Nutraceutical Mushrooms, Part 1 Jul 14, 2026

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Mushrooms for Sleep and Cognitive Support: Jim LaValle, a clinical pharmacist, author, and board-certified clinical nutritionist, details Wakunaga/Kyolic’s new Specialty Series mushroom products and related health strategies. He reveals a sleep formula with reishi, L-theanine, valerian, and Aged Garlic Extract aimed at calming stress and supporting better sleep. The formula for cognition includes lion’s mane for memory support and aronia berry antioxidants. He also emphasizes Aged Garlic Extract’s heart benefits.

Unlocking the Power of Nutraceutical Mushrooms, Part 2 Jul 14, 2026

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Dr. Hoffman continues his conversation Jim LaValle, a clinical pharmacist, author, and board-certified clinical nutritionist.

Intelligent Medicine Radio Show for July 11, Part 1: Internal Visceral Fat May Accelerate Brain Aging Jul 13, 2026

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Carnitine, with acknowledged muscle and brain benefits, may find a new role in supporting cancer immunity; Calcium and vitamin D’s bone-building impact may be limited; Internal visceral fat may accelerate brain aging, MRI study finds; The remarkable benefits of a newly-discovered mitochondrial booster—urolithin A (Mitopure®️).

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