Infectious Disease Puscast

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Infectious Disease Puscast #37 Sep 18, 2023

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On episode #37 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 8/31 – 9/13/23.

Host: Daniel Griffin and Sara Dong

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Association between varicella zoster virus and dementia (NS)
Safety, efficacy, and immunogenicity of V160 vaccine in cytomegalovirus-seronegative women (The Lancet)
Microorganisms detected in intussusception cases and controls in children (OFID)
Clinician testing and treatment thresholds for management of UTIs (OFID)
Clinical outcomes and management of NAAT-positive/toxin-negative Clostridioides difficile infection (CID)
Associations of standard care, intrathecal antibiotics, and antibiotic impregnated catheters with cerebrospinal fluid shunt infection (JPIDS)
Advances in asynchronous telemedicine call for increased antibiotic surveillance (CID)
Two artificial tears outbreak-associated cases of extensively drug-resistant Pseudomonas aeruginosa detected through whole genome surveillance (JID)
Pre-XDR congenital TB in an extremely premature baby (CID)
Emerging Roles of (1→3)-β-D-glucan in cerebrospinal fluid for detection and therapeutic monitoring of fungal diseases (CID)
Outbreak of locally acquired mosquito-transmitted malaria (CDC)
Complexity of infectious diseases compared to other cognitive medical subspecialties (OFID)
Risk of opportunistic infections associated with long-term glucocorticoid therapies in adults (CID)

Music is by Ronald Jenkees

Infectious Disease Puscast #36 Sep 05, 2023

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On episode #36 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 8/17 – 8/30/23.

Host: Daniel Griffin

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Detection of rotavirus in respiratory specimens from children aged under 2 years hospitalized for acute gastroenteritis (JID)
Risk of Bell's palsy following SARS-CoV-2 infection (CMI)
Evaluation and management of diabetes-related foot infections (CID)
Impact of mandatory infectious disease specialist approval on Clostridioides difficileinfection rates and testing appropriateness (CID)
Role of cerebral imaging on diagnosis and management in patients with suspected infective endocarditis (CID)
Identifying effective durations of antibiotic therapy for the treatment of carbapenem-resistant Enterobacterales bloodstream infections (CID)
Impact on clinical outcome of follow-up blood cultures and risk factors for persistent bacteraemia (CMI)
State-of-the-art review: Neurosyphilis (CID)
Oritavancin compared to the standard of care for treatment of non-endovascular gram-positive bloodstream Infections (OFID)
How to approach suppressive antibiotic therapy following debridement, antibiotics, and implant retention for prosthetic joint infection (CID)
2023 Duke-International Society for cardiovascular infectious diseases criteria for infective endocarditis (CID)
Adjunctive diagnostic studies completed following detection of candidemia in children (JPIDS)
Oral lipid nanocrystal amphotericin b for cryptococcal meningitis (CID)
Efficacy of 23 commonly used liquid disinfectants against Candida auris (IC&HE)
Burrow ink test for scabies (NEJM)
Evolution of partial resistance to artemisinins in malaria parasites in Uganda (NEJM)
Human neural larva migrans caused by Ophidascaris robertsi ascarid (EID)

Music is by Ronald Jenkees

Infectious Disease Puscast #35 Aug 25, 2023

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On episode #35 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 8/3 – 8/16/23.

Host: Daniel Griffin

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Powassan virus encephalitis: a tertiary center experience (CID)
Diagnostic accuracy of hospital antibiograms in predicting the risk of antimicrobial resistance in Enterobacteriaceae isolates (CID)
Timely diagnosis of incubating syphilis infections using Treponema pallidum (CID)
Impact of rapid identification and stewardship intervention on coagulase-negative Staphylococcus bloodstream infection (OFID)
Natural antibodies mediate protection against Acinetobacter baumannii respiratory infections (JID)
Risk of misleading conclusions in observational studies of time-to-antibiotics and mortality in suspected sepsis (CID)
Cryptococcal meningitis in young, immunocompetent patients (OFID)
Experimental acquisition, maintenance, and transmission of methicillin-resistant Staphylococcus aureus (MRSA) (JID)
Clinical characteristics and prognosis of pediatric Phthirus pubis coinfestation of the eyelashes and scalp hairs (AMJTMH)
Prognostic significance of Lymphocyte Subpopulations for ICU-acquired Infections in sepsis patients (JHI)

Music is by Ronald Jenkees

Infectious Disease Puscast #34 Aug 08, 2023

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On episode #34 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/20 – 8/2/23.

Host: Daniel Griffin

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FDA approves first treatment for molluscum contagiosum (FDA)
Identifying children likely to benefit from antibiotics for Acute Sinusitis (JAMA)
Impact of metagenomic next-generation sequencing of plasma cell-free DNA testing in patients with suspected infectious diseases (OFID)
Impact of infectious diseases consultation in patients with candidemia at a multisite healthcare system (OFID)
Relapsing babesiosis with molecular evidence of resistance to certain antimicrobials commonly used to treat Babesia microti infections (OFID)
Seroprevalence of Chagas disease among people of Latin American descent (AJTMH)
Malaria transmission-blocking vaccines Pfs230D1-EPA and Pfs25-EPA in Alhydrogel in healthy Malian adults (The Lancet)
The human blood fluke, Schistosoma mansoni, harbors bacteria throughout the parasite's life cycle (JID)
Health care provider knowledge regarding Alpha-gal syndrome (CDC)

Music is by Ronald Jenkees

Infectious Disease Puscast #33 Jul 25, 2023

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On episode #33 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/6 – 7/19/23.

Host: Daniel Griffin

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Early antiretroviral therapy not associated with higher cryptococcal Meningitis mortality in people with HIV in high-income countries (CID)
Implementing a rapid Antiretroviral therapy program using starter packs for emergency department patients diagnosed with HIV infection (OFID)
Efficacy of a clinical decision rule to enable direct oral challenge in patients with low-risk Penicillin allergy (JAMA)
Infectious diseases consultation associated with reduced mortality in gram-negative bacteremia (CID)
Positive impact of [18F]FDG-PET/CT on mortality in patients with Staphylococcus aureus Bacteremia explained by immortal time bias (CID)
Azithromycin for bacterial watery diarrhea (JID)
Periprosthetic joint infection: current clinical challenges (CID)
Old World medieval Treponema pallidum complex treponematosis (JID)
Clinical Impact of polymerase chain reaction–based Aspergillus and Azole resistance detection in invasive aspergillosis (CID)
Superior accuracy of Aspergillus plasma cell-free DNA PCR over serum galactomannan for the diagnosis of invasive aspergillosis (CID)
Tafenoquine co-administered with dihydroartemisinin–piperaquine for the radical cure of Plasmodium vivax malaria (The Lancet)
Doubling of cyclosporiasis cases partially attributable to a salad kit (CDC)
Efficacy and safety of adjunctive corticosteroids in the treatment of severe community-acquired pneumonia (BMC)

Music is by Ronald Jenkees

Infectious Disease Puscast #32 Jul 12, 2023

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On episode #32 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/21 – 7/4/23.

Hosts: Daniel Griffin and Sara Dong

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Clinical characteristics and outcomes among travelers with severe dengue (AIM)
Phase 3 randomized trial of Bulevirtide in chronic hepatitis D (NEJM)
Increased peripheral inflammation associated with structural brain changes and reduced blood flow in virologically controlled people with HIV (JID)
Sustained viral suppression with dolutegravir monotherapy over 192 weeks in HIV patients (CID)
Side-by-side comparative study of the immunogenicity of the intramuscular and intradermal rabies post-exposure prophylaxis regimens in suspected RABV exposed individuals (CID)
Reliability of admission procalcitonin testing for capturing bacteremia across the sepsis spectrum (CCM)
Early discontinuation of antibiotics in patients admitted with clinically suspected serious infection but negative cultures (OFID)
Short-course therapy for urinary tract infections in children (JAMA)
Autochthonous Leprosy in the United States (NEJM)
Management of pediatric pneumonia (CID)
Added value of (1,3)-β-D-glucan for the diagnosis of Invasive candidiasis in ICU patients (Infection)
Selection for insecticide resistance can promote Plasmodium falciparum infection in Anopheles (PLOS Pathogens)
Locally acquired malaria cases identified in the US (CDC)
Nanoplasmonic amplification in microfluidics enables accelerated colorimetric quantification of nucleic acid biomarkers from pathogens (NN)

Music is by Ronald Jenkees

Infectious Disease Puscast #31 Jun 28, 2023

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On episode #31 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/8 – 6/20/23.

Hosts: Daniel Griffin and Sara Dong

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Links for this episode

Relative effectiveness of the cell-based quadrivalent influenza vaccine in preventing cardiorespiratory hospitalizations (OFID)
Evaluation of Oseltamivir used to prevent hospitalization in outpatients with influenza (JAMA)
Pan-ebolavirus monoclonal antibody cocktail provides protection against Ebola and Sudan viruses (JID)
Inappropriate antibiotic prescribing and its determinants among outpatient children in low-and middle-income countries (PLOS)
IDSA 2023 Guidance on the treatment of antimicrobial resistant gram-negative infections (IDSA)
Evaluating antimicrobial duration for gram-negative bacteremia in patients with neutropenia (TID)
Antibiotic myths for the ID clinician (CID)
Dalbavancin for the treatment of acute bacterial skin and skin structure infection in patients with obesity or Diabetes (OFID)
Global differences in the management of S. aureus bacteremia (CID)
Clinical risk Scores to Predict Trimethoprim-Sulfamethoxazole, Fluoroquinolone, Nitrofurantoin, and Cephalosporin non-susceptibility among outpatient episodes of complicated UTI among adults (OFID)
Continuous vs intermittent meropenem administration in critically ill patients with sepsis (JAMA)
Current pyuria cutoffs promote inappropriate UTI diagnosis in older women (CID)
Paenibacillus infection as a novel cause of sepsis in term neonates with high risk of sequelae in Uganda (CID)
Antimicrobial for 7 or 14 Days for febrile urinary tract infection in men (CID)
Candida auris‒associated hospitalizations (EID)
Fatal invasive mold infections after transplantation of organs recovered from drowned donors (EID)

Music is by Ronald Jenkees

Infectious Disease Puscast #30 Jun 13, 2023

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On episode #30 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/24 – 6/7/23.

Hosts: Daniel Griffin and Sara Dong

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Links for this episode

Foodborne illness outbreaks at retail food establishments (CDC)
Donor-derived fulminant herpes simplex virus hepatitis after liver transplantation (TID)
High-dose influenza vaccine is associated with reduced mortality among older adults with breakthrough influenza (CID)
Letermovir vs valganciclovir for prophylaxis of cytomegalovirus in high-risk kidney transplant recipients (JAMA)
Association between combination antibiotic therapy as opposed as monotherapy and outcomes of ICU patients with pneumonia (CC)
Safety of Streptococcus pyogenesvaccines (CID)
Meningococcal ACWYX conjugate vaccine in 2 to 29 year olds (NEJM)
Orthopaedic surgical management of pressure-ulcer related pelvic osteomyelitis (OFID)
On culture and blood cultures (CMI)
Benchmarking of outpatient pediatric antibiotic prescribing (JPIDS)
Outbreak of suspected fungal meningitis in US patients who underwent surgical procedures under epidural anesthesia (CDC)
Risk of systemic fungal infections after exposure to wildfires (The Lancet)
Giardia duodenalis and dysentery in Iron Age Jerusalem (Parastiology)
Community water fluoridation levels to promote effectiveness and safety in oral health (CDC)

Music is by Ronald Jenkees

Infectious Disease Puscast #29 Jun 07, 2023

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On episode #29 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/11 – 5/23/23.

Hosts: Daniel Griffin and Sara Dong

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Links for this episode

Harmonie phase IIIb study trial results of nirsevimab against RSV lower respiratory tract infection hospitalization for infants (ESPID)
Mogamulizumab for treatment of HTLV-1 associated Myelopathy/Tropical Spastic Paraparesis (IDSA)
Revised protocol for secondary prevention of congenital cytomegalovirus infection with valaciclovir (IDSA)
Increase in false positive fourth generation HIV tests in patients with COVID-19 (CID)
Implementation of an antibiotic stewardship initiative in a large urgent care network (JAMA)
Clindamycin + vancomycin versus linezolid for treatment of necrotizing soft tissue infection (OFID)
Assessing empiric antimicrobial therapy with the dundee classification for skin and soft tissue infections (OFID)
Combination of amoxicillin 3000mg and probenecid vs 1500mg amoxicillin monotherapy for treating syphilis in patients with HIV (CID)
The sympathetic nervous system is necessary for development of CD4+ T cell memory following Staphylococcus aureus infection (JID)
Efficacy and safety of sulbactam-durlobactam versus colistin for the treatment of patients with infections caused by Acinetobacter baumannii-calcoaceticu complex (The Lancet)
First reported US cases of tinea caused by Trichophyton indotineae (CDC)
How to use direct microscopy for diagnosing fungal infections (CMI)
Limited Cutaneous Leishmaniasis as Ulcerated Verrucous Plaque on leg (EID)
Can Ivermectin kill Sarcoptes scabieiduring the molting process? (PLOS)
The Infectious Diseases Specialist, at risk of extinction (JID)
Ticks harbor and excrete chronic wasting disease prions (NIH)

Music is by Ronald Jenkees

Infectious Disease Puscast #28 May 30, 2023

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On episode #28 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/26 – 5/10/23.

Hosts: Daniel Griffin and Sara Dong

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Links for this episode

Unprecedented outbreak of West Nile Virus (CDC)
Approval of first RSV vaccine approved for individuals 60 years and older (FDA)
FDA approves orally administered fecal microbiota product for the prevention of recurrence of C-difficile (FDA)
Using thermal imaging to track cellulitis (OFID)
Burden of Typhoid and Paratyphoid fever in India (NEJM)
Early switch to oral antimicrobials in brain abscess (CMI)
Considering vancomycin alternatives for pediatric methicillin-resistant Staphylococcus aureus bacteremia (JPIDS)
Navigating treatment options for Carbapenem-Resistant Acinetobacter baumannii-calcoaceticus complex infections (CID)
2023 Duke-ISCVID criteria for infective Endocarditis (CID)
Molecular characterization of Candida auris outbreak isolates in Qatar from COVID-19 patients (CMI)
Amplicon sequencing reveals complex infection in infants congenitally infected with Trypanosoma cruzi (JID)
Impact of Sequestration on Artemisinin-Induced Parasite Clearance in Plasmodium falciparum Malaria (CID)
Advances in artificial intelligence for infectious disease surveillance (NEJM)

Music is by Ronald Jenkees

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