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    Natural Sciences

    Infectious Disease Puscast

    A review of the infectious diseases literature from the previous two weeks.

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    Copyright: © 2022

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    Latest Episodes:
    Infectious Disease Puscast #47 Feb 06, 2024
    Show notes

    On episode #46 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/18 – 1/31/24.

    Hosts: Daniel Griffin and Sara Dong

    Subscribe (free): Apple Podcasts, RSS, email

    Become a patron of Puscast!

    Links for this episode
    • Viral
    • Reinfection by Zika via genome diversity and antibody response (EID-Emerging Infectious Disease)
    • People with HIV should breast/chest feed (CID)
    • Norovirus GII in the water (PLoS Water)
    • Herpes zoster and duloxetine premedication for neuralgia (CID)
    • Bacterial
    • SABATO: early oral switch trial (Lancet)
    • Guideline for concordant antibiotic therapy to treat community-acquired pneumonia (Chest)
    • Ceftriaxon with or without Nafcillin/Oxacillin for MSSA treatment (OFID)
    • Ceftriaxone to prevent ventilator-associated pneumonia trial (Lancet)
    • Azithromycin part of routine well-infant visits (NEJM)
    • Burkholderia pseudomallei in Mississippi(NEJM)
    • Cefiderocol red wine urine syndrome in children (Pediatric Infectious Disease Journal)
    • Fungal
    • InsuranceClaims equals blastomycosis Incidence (EID)
    • Antimicrobial stewardship for coccidioidomycosis in endemic region (OFID)
    • Endemic mycosesafter solid organ transplantation (OFID)
    • Parasitic
    • Headbobbing trematoda (CMI)
    • Miscellaneous
    • Suspected hemophagocytic lymphohistiocytosis (JPIDS)
    • BioFire FilmArray for real-life assessment of hospitalized respiratory illness (JID)
    • Clinical microbiology conferences gender and geography (Lancet)
    • Is the toilet really the greatest sanitation invention? (AJICJ)

    Music is by Ronald Jenkees


    Infectious Disease Puscast #46 Jan 24, 2024
    Show notes

    On episode #46 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/4 – 1/17/24.

    Hosts: Daniel Griffin and Sara Dong

    Subscribe (free): Apple Podcasts, RSS, email

    Become a patron of Puscast!

    Links for this episode
    • Comparing the performance of three models incorporating weather data to forecast dengue epidemics (JID)
    • Elucidating the impacts of climate on dengue transmission through mathematical models (JID)
    • Infants receiving a single dose of nirsevimab to prevent RSV do not have evidence of enhanced disease in their second RSV season (JPIDS)
    • Patient perspectives on solid organ transplantation from donors with hepatitis C viremia to recipients without hepatitis C viremia (OFID)
    • Oral Beta-Lactams, Fluoroquinolones, or Trimethoprim-Sulfamethoxazole for definitive treatment of uncomplicated Escherichia coli or Klebsiella species bacteremia from a urinary source (OFID)
    • Discontinuation of contact precautions for methicillin-resistant Staphylococcus aureusin a pediatric healthcare system (JPIDS)
    • Oral linezolid compared with benzathine PCN G for treatment of early syphilis in adults (The Lancet)
    • Model-informed precision dosing improves outcomes in patients receiving vancomycin for gram-positive infections (OFID)
    • The Xpert MTB/RIF cycle threshold value predicts M.tuberculosis transmission to close contacts (CID)
    • Efficacy and safety of a structured de-escalation from antipseudomonal β-lactams in bloodstream infections due to Enterobacterales (The Lancet)
    • Oral antibiotics for treatment of Gram negative bacteremia in solid organ transplant recipients (CID)
    • Dematiaceous fungal keratitis with tentacles mimicking Pythium Keratitis (Jama)
    • Verification, analytical sensitivity, cost-effectiveness, and comparison of four Candida auris screening methods (OFID)
    • Tafenoquine-Atovaquone combination achieves radical cure and confers sterile immunity in experimental models of human babesiosis (JID)
    • Relapsing babesiosis with molecular evidence of resistance to certain antimicrobials commonly used to treat Babesia microti infections (OFID)
    • Understanding parental leave policies in ID fellowship (OFID)
    • What's hot this year in ID clinical science (CID)

    Music is by Ronald Jenkees


    Infectious Disease Puscast #45 Jan 10, 2024
    Show notes

    On episode #45 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 12/20/23 – 1/3/24.

    Hosts: Daniel Griffin and Sara Dong

    Subscribe (free): Apple Podcasts, RSS, email

    Become a patron of Puscast!

    Links for this episode
    • Notes coming soon
    • Bacterial
    • Change in oral PrEP affect kidney function (OFID)
    • Preventing STIs in women (NEJM)
    • Revising antibiotic and STI trials (NEJM)
    • Treatment for pediatric febrile UTIs (Pediatrics)
    • Burkholderia pseudomallei in Mississippi (NEJM)
    • Acute kidney injury and gentamicin treatment for endocarditis (JACAMR)
    • Pacemakers for Lyme disease patients (OFID)
    • Pseudomonas aeruginosa update and must have references (CMI)
    • Fungal
    • Definining optimal dose liposomal amphotericin B for Candida auris (JID)
    • Cryptococcus neoformans and HIV serology (OFID)
    • Global emergence of Candida auris (OFID)
    • Novel anti-cancer therapeutics and fungal biology (PLoS Pathogens)
    • Parasitic
    • Second malaria vaccine prequalified (WHO)
    • Seasonal vaccination against malaria in children (Lancet ID)
    • Toxoplasma gondii treatement guidelines for patients with haematological malignancies (Lancet ID)
    • Miscellaneous
    • Eye infection review (NEJM)
    • Diagnosing children with gastroenteritis using molecular testing (CID)
    • Are hospital coffee machines pathogenic (BMJ)
    • Putting down the fluoroquinolone (CID)

    Music is by Ronald Jenkees


    Infectious Disease Puscast #44 Dec 27, 2023
    Show notes

    On episode #44 of the Infectious Disease Puscast, Sara reviews the infectious disease literature for the weeks of 12/8 – 12/20/23.

    Hosts: Daniel Griffin and Sara Dong

    Subscribe (free): Apple Podcasts, RSS, email

    Become a patron of Puscast!

    Links for this episode
    • Mpox and chickenpox co-infection (J Inf Dis)
    • Corticosteroids for postherpetic neuralgia (Coch Data Syst Rev)
    • Dengue incidence and mortality in Bangladesh (J Inf Dis)
    • ACORN trial vancomycin and piperacillin-tazobactam (Open For Inf Dis)
    • Models for infection risk in children with cancer (J Clin Oncol)
    • Salmonella outbreak from cantaloupes (CDC)
    • Pediatric antimicrobial stewardship programs ( Ped Inf Dis Soc)
    • MRSA nasal swab PCR assay (J Ped Inf Dis Soc)
    • Invasive meningococcal disease (Open For Inf Dis)
    • Probiotics for recurrent UTI (Clin Inf Dis)
    • Preservation fluid contamination and kidney transplant patients (Transpl Inf Dis)
    • Mechanism of zinc prevention of candidiasis (Sci Transl Med)
    • Risk factors for invasive fungal infection (Open For Inf Dis)
    • Genetic variants associated with S. mansoni worm burden (PLoS NTD)
    • Chagas disease GI manifestations (Am J Trop Med Hyg)
    • Wolbachia in Aedes aegypti in Colombia (PLoS NTD)

    Music is by Ronald Jenkees


    Infectious Disease Puscast #43 Dec 15, 2023
    Show notes

    On episode #43 of the Infectious Disease Puscast, Sara reviews the infectious disease literature for the weeks of 11/22 – 12/06/23.

    Host: Sara Dong

    Subscribe (free): Apple Podcasts, RSS, email

    Become a patron of Puscast!

    Links for this episode
    • Treatment for first cytomegalovirus infection post-hematopoietic cell transplant (CID)
    • Mortality among children aged antiretroviral treatment (CDC)
    • Boostability after single-visit pre-exposure prophylaxis with rabies vaccine (The Lancet)
    • Alarming trends in dengue incidence and mortality in Bangladesh (JID)
    • Update on cardiovascular implantable electronic device infections and their prevention, diagnosis, and management (Circulation)
    • SCCM/IDSA guidelines for evaluating new fever in adult patients in the ICU (IDSA)
    • Risk factors for serogroup B meningococcal disease among college students (OFID)
    • Comparison of Adjuvant Clindamycin vs Linezolid for severe invasive Group A Streptococcal skin and soft tissue infections (OFID)
    • State of the art reviews: Persistent enterococcal bacteremia (CID)
    • Billirud Mill Blastomycosis outbreak (MM)
    • Primaquine radical cure in patients with P.falciparum malaria in areas co-endemic for P falciparum and P vivax (The Lancet)
    • Microbiology, public health, and the murals of Diego Rivera (CID)

    Music is by Ronald Jenkees


    Infectious Disease Puscast #42 Nov 28, 2023
    Show notes

    On episode #42 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 11/09 – 11/21/23.

    Host: Daniel Griffin and Sara Dong

    Subscribe (free): Apple Podcasts, RSS, email

    Become a patron of Puscast!

    Links for this episode
    • Progress toward measles elimination (CDC)
    • Slaying the troll of transplantation (TID)
    • Association between the neutrophil-to-lymphocyte ratio and adverse outcomes in children aged
    • Pre-exposure prophylaxis use history in people with antiretroviral resistance at HIV diagnosis (CID)
    • Impact of the 2019 FDA guidance for uncomplicated UTI on treatment response rates (OFID)
    • CDC Guidelines for the prevention and treatment of anthrax (CDC)
    • Contemporary use of cefazolin for MSSA infective endocarditis (IJID)
    • Is carbapenem therapy necessary for treatment of non-CTX-M ESBL-producing Enterobacterales bloodstream infections (CID)
    • Infectious diseases consultation associated with reduced mortality in gram-negative Bacteremia (CID)
    • Contemporary management of Staphylococcus aureus bacteremia (CID)
    • Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal (Nature)
    • Impact of in-house Candida auris PCR screening on admission on the incidence rates of surveillance and blood cultures with C. auris and associated cost savings (OFID)
    • Human lobomycosis caused by Paracoccidioides loboi (EID)
    • Molecular surveillance detects high prevalence of the neglected parasite Mansonella ozzardi (JID)
    • Efficacy and safety of moxidectin compared with ivermectin against Strongyloides stercoralis infection in adults (The Lancet)
    • Efficacy of bortezomib for treating anti-interferon-gamma autoantibody-associated adult-onset immunodeficiency (AOID) syndrome (CID)
    • Investigational non-antibiotic therapeutics for infections in hematopoietic cell transplant recipients and patients with hematologic malignancies receiving cellular therapies (TID)
    • Black box warning: large language models and the future of infectious diseases consultations (CID)

    Music is by Ronald Jenkees


    Infectious Disease Puscast #41 Nov 13, 2023
    Show notes

    On episode #41 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/26 - 11/08/23.

    Host: Daniel Griffin and Sara Dong

    Subscribe (free): Apple Podcasts, RSS

    Become a patron of Puscast!

    Links for this episode
    • Intrinsic and effective severity of COVID-19 cases infected with the ancestral strain and Omicron BA.2 variant in Hong Kong (JID)
    • Efficacy and safety of corticosteroid therapy for community-acquired pneumonia (CID)
    • Hydrocortisone in severe community-acquired pneumonia (NEJM)
    • Early oral antibiotic switch in Staphylococcus aureus bacteraemia (CID)
    • Outbreak of invasive Group A Streptococcus in children (PIDS)
    • Inhaled amikacin to prevent ventilator-associated pneumonia (NEJM)
    • Assessing risk for complications in acute hematogenous osteomyelitis in children (JPIDS)
    • Empirical antibiotic therapy in diabetic foot ulcer infection increases hospitalization(OFID)
    • 2023 guideline on diagnosis and management of acute bacterial arthritis in pediatrics (JPIDS)
    • Natural history of antibiotic-treated lower limb cellulitis (OFID)
    • Missed opportunities for preventing congenital syphilis (CDC)
    • Diverse clinical manifestations and challenges of mucormycosis (OFID)
    • Malaria (The Lancet)
    • Clinical characteristics and outcomes of Chagas disease (AJTMH)
    • Direct gloving vs hand hygiene before donning gloves in adherence to hospital infection control practices (JAMA)
    • How I approach diarrhea in hematological transplant patients (TID)
    • Innovating pediatric infectious diseases recruitment and training (JPIDS)

    Music is by Ronald Jenkees


    Infectious Disease Puscast #40 Oct 31, 2023
    Show notes

    On episode #40 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/13 – 10/25/23.

    Host: Daniel Griffin and Sara Dong

    Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

    Become a patron of Puscast!

    Links for this episode
    • Sustained viral suppression with dolutegravir monotherapy over 192 weeks in patients starting combination antiretroviral therapy during primary HIV infection (CID)
    • Dolutegravir monotherapy possibly boosted by highly active natural immunity (CID)
    • Mpox neutralizing antibodies at 6 months from mpox infection or MVA-BN vaccination (The Lancet)
    • Linezolid population pharmacokinetic model in plasma and cerebrospinal fluid among patients with tuberculosis meningitis (JID)
    • Adjunctive dexamethasone for tuberculous meningitis in HIV-positive adults (NEJM)
    • Cefepime vs piperacillin-tazobactam in adults hospitalized with acute infection (JAMA)
    • Acute kidney injury with empirical antibiotics for sepsis (JAMA)
    • Mycobacterium abscessus outbreak related to contaminated water among ventilator-dependent residents of a pediatric facility (CDC)
    • Trial of Vancomycin and Cefazolin as surgical prophylaxis in arthroplasty (NEJM)
    • Trimethoprim-sulfamethoxazole significantly reduces the risk of nocardiosis in solid organ transplant recipients (CMI)
    • Risk of hematologic cancers among individuals tested for Borrelia burgdorferi antibodies, and Borrelia burgdorferi seropositive individuals (CMI)
    • In vitro susceptibility patterns for slowly growing non-tuberculous mycobacteria (JAC)
    • Real-world use of mold-active triazole prophylaxis in the prevention of invasive fungal diseases (OFID)
    • Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19 (INI)
    • Real-time dermoscopy of numerous mites crawling on the crusted scabies (CMI)
    • The African eye worm: current understanding of the epidemiology, clinical disease, and treatment of loiasis (The Lancet)
    • Decolonization in nursing homes to prevent infection and hospitalization (NEJM)
    • Can chatbot artificial intelligence replace ID physicians in the management of bloodstream infections (CID)
    • Nasal iodophor antiseptic vs nasal mupirocin antibiotic in the setting of chlorhexidine bathing to prevent infections in ICUs (JAMA)
    • FDA Approves PENBRAYATM for the prevention of the five most common serogroups causing meningococcal disease in adolescents (Pfizer)

    Music is by Ronald Jenkees


    Infectious Disease Puscast #39 Oct 23, 2023
    Show notes

    On episode #39 of the Infectious Disease Puscast, recorded at IDWeek in Boston, Daniel and special host Priya Kodiyanplakkal review the infectious disease literature for the weeks of 9/27 – 10/12/23.

    Host: Daniel Griffin and Priya Kodiyanplakkal

    Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

    Become a patron of Puscast!

    Links for this episode
    • Survival from rabies in a young child from India (AJTMH)
    • The perils of overly-sensitive viral load testing for persons living with HIV (OFID)
    • Letermovir vs Valganciclovir for prophylaxis of Cytomegalovirus in high-risk kidney transplant recipients (JAMA)
    • Frailty and survival in the 1918 influenza pandemic (PNAS)
    • Adverse pregnancy outcomes among HIV-infected Women taking isoniazid preventive therapy during the first trimester (CID)
    • Ceftobiprole for treatment of complicated Staphylococcus aureus bacteremia (NEJM)
    • Real-world application of oral therapy for infective endocarditis (CID)
    • Efficacy and safety of sulbactam–durlobactam versus colistin for the treatment of patients with serious infections (The Lancet)
    • Information delay of significant bloodstream isolates and patient mortality (CID)
    • Critical appraisal beyond clinical guidelines for intra-abdominal candidiasis (CC)
    • Update on outbreak of fungal meningitis among Americans who received epidural anesthesia at clinics in Mexico
    • Increasing prevalence of artemisinin-resistant HRP2-negative malaria in Eritrea (NEJM)
    • Gender differences in psychosocial determinants of hand hygiene among physicians (ICHE)

    Music is by Ronald Jenkees


    Infectious Disease Puscast #38 Oct 06, 2023
    Show notes

    On episode #38 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 9/14 – 9/27/23.

    Host: Daniel Griffin and Sara Dong

    Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

    Become a patron of Puscast!

    Links for this episode
    • Features of Long COVID identified through immune profiling (Nature)
    • Severity of influenza-associated hospitalizations by influenza type (The Lancet)
    • Cefazolin for the treatment of CNS infections (CID)
    • Rifampin based therapy for patients with Staphylococcus aureus native vertebral Osteomyelitis (CID)
    • State of the management of infections caused by multidrug-resistant organisms (CID)
    • Are contact precautions "essential" for the prevention of healthcare-associated methicillin-resistant Staphylococcus aureus? (CID)
    • Impact of the sequential implementation of a pharmacy-driven methicillin-resistant Staphylococcus aureus (MRSA) nasal-swab ordering policy and vancomycin 72-hour restriction protocol on standardized antibiotic administration ratio (ICHE)
    • Update on outbreak of fungal meningitis among US residents who received epidural anesthesia at two clinics in Mexico (CID)
    • Paratracheal abscess by plant fungus Chondrostereum purpureum (MMCR)
    • Canadian Blood Services traceback investigation of a suspected case of transfusion-transmitted malaria (Transfusion)
    • Strongyloides infection screening in transplant candidates (TID)
    • The world of microbial odors (JID)

    Music is by Ronald Jenkees


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