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    Health & Fitness

    GI Pearls Podcast

    Gastroenterology Literature Review

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    Latest Episodes:
    GI Pearls - September 2020 Sep 10, 2020
    Show notes

    Show notes for Episodes 43 – September 2020

    1. Levels of Vitamin D are low after Crohn’s disease is established but not before – CGH
    2. Rapid recurrence of EOE activity after successful treatment in the observational phase of a randomised trial. – CGH
    3. Clinical outcomes of adults with eosinophilic esophagitis with severe stricture. – GIE
    4. Quality of Colonoscopy: A Comparison Between Gastroenterologists and Nongastroenterologists – Dis of colon & Rectum.
    5. A Novel Score to Predict Esophageal Varices in Patients with Compensated Advanced Chronic Liver Disease – DDS
    6. https://cookcountyscore.shinyapps.io/cookcountyscore/
    7. Outcomes of Gallbladder Polyps and Their Association With Gallbladder Cancer in a 20-Year Cohort – JAMA Network
    8. Discordance Between Patient-Reported Outcomes and Mucosal Inflammation in Patients With Mild to Moderate Ulcerative Colitis – CGH
    9. Rifabutin-Based triple therapy for Hpylori Eradication – Annals of IM
    10. Does Gastric Bypass Improve Glycemic Control Beyond the Effect of Weight Loss? – NEJM
    11. Regression of Fibrosis Stage With Treatment Reduces Long-Term Risk of Liver Cancer in Patients w/ Hemochromatosis Caused by Mutation in HFE – CGH
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    GI Pearls July - 2020 Aug 17, 2020
    Show notes

    Show notes for Episodes 42 – July/August 2020

    1. Use of total underwater colonoscopy to navigate endoscopic challenges – CGH
    2. Performance of radiographic imaging after incomplete colonoscopy for non-malignant causes in clinical practice. – GIE
    3. Cognitive Deficit and white matter changes in persons with celiac disease: a population based study. -Gastroenterology
    4. Endoscopic gastric body plication for the treatment of obesity – GIE
    5. Cold snare piecemeal EMR of large sessile colnic polylps >20mm – GIE
    6. AGA clinical Practice Update on Functional Heartburn: Expert Review – Gastro
    7. Imipramine for Treatment of Esophageal Hypersensitivity and Functional Heartburn – Am J Gastro
    8. Superiority of Higher‑Volume Fresh Feces Compared to Lower‑Volume Frozen Feces in Fecal Microbiota Transplantation for Recurrent Cdiff – Dig Dis & Sciences
    9. Practical Tips on TIPS: When and When NOT to request it.
    10. TIPS to the rescue: Preoperative Transjugular Intrahepatic Portosystemic Shunt (TIPS) placement in a patient with caput medusae and colon cancer – Radiology Case Reports
    11. Real-World practice patterns in the Era of Rectal Indomethacin for prophylaxis against Post-ERCP Pancreatitis in a high risk cohort – AmJ Gastro
    12. Delays in colonoscopy start time are associated with reductions in adenoma detection rates – Digest Liver Dis
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    GI Pearls June - 2020 Jul 06, 2020
    Show notes

    Show notes for Episodes 41 – June 2020

    1. Discrepancy between self-reported and actual colonoscopy polypectomy practices for the removal of small polyps – GIE
    2. AGA Guidelines on the management of Moderate to Severe Ulcerative Colitis – Gastro
    3. Resistance training increases muscle strength and muscle size in patients with liver cirrhosis. – CGH
    4. Reduced incidence of Hepatic encephalopathy and higher odds of resolutions associated with eradication of HCV – CGH
    5. Ammonia Levels do not guide clinical management of patients with hepatic encephalopathy caused by cirrhosis. – Am J Gastro
    6. Low-Value Levels: Ammonia Testing Does not Improve the Outcomes of HE. – Am J Gastro
    7. Young adults and metachronous neoplasia: risks for future advanced adenomas and large serrated polyps compared with older adults – GIE
    8. Changing patters in the epidemiology and outcomes of IBD in the UK – 2000-2018 – AP&T
    9. Use of Fecal Occult Blood Testing as a Diagnostic Tool for Clinical Indications: SRMA – Am J Gastro
    10. Low incidence of aerodigestive cancers in patients with negative results from colonoscopies, regardless of findings from stool DNA tests. – CGH
    11. Endoscopic retrieval of magnetic foreign body ingestions with a nasal bridle: description of a novel technique – GIE
    12. Underwater versus conventinal endoscopic resection of nondiminutive nonpedunculated colorectal lesions: RCT – GIE
    13. Cancer Prevention With Aspirin in Hereditary Colorectal Cancer (Lynch Syndrome), 10-year Follow-Up – Lancet
    14. AGA and Allergy Immunology Guidelines for EOE – Gastro
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    GI Pearls May - 2020 May 16, 2020
    Show notes

    Show notes for Episodes 40 – May 2020

    1. Choosing a prokinetic for your patient beyond metoclopramide – AmJ Gastro
    2. Ultraprocessed Food Consumption and Risk of T2DM among participants of the NutriNet-Sante Prospective Cohort – JAMA Int Med
    3. Diagnosis and Treatment of Clostridioides (Clostridium) difficile Infection in Adults in 2020 – JAMA
    4. Clinical importance of cold polypectomy during the insertion phase in the left side of the colon and rectum: multicenter randomized controlled trial (PRESECT study). – GIE
    5. Timing of endoscopy for Acute Upper Gastrointestinal Bleeding – NEJM
    6. Trends in US Burden of C.difficile infection – NEJM
    7. Mechanism, Evaluation and Management of Chronic Constipation – Gastroenterology
    8. Undisclosed payments by pharmaceutical and medical device manufacturers to authors of endoscopy guidelines in the United States – GIE
    9. Managing conflicts of interest in clinical practice guidelines – GIE
    10. Hepatopulmonary Syndrome – NEJM
    11. Reversal of Digital Clubbing After Lung Transplantation in Cystic Fibrosis Patients: A Clue to the Pathogenesis of Clubbing – Pediatr Pulmonol.
    12. Infectious Proctitis – NEJM
    13. Intestinal Lipomatosis – NEJM
    14. EUS-guided gastroenteric anastomosis as a bridge to definitive treatment in benign gastric outlet obstruction – GIE
    15. Uptake of Colorectal Cancer Screening by Physicians Is Associated With Greater Uptake by Their Patients – Gastro
    16. Immunosuppression in Autoimmune Hepatitis: Is There an End Game? – Am J Gastro
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    GI Pearls March/April- 2020 Apr 01, 2020
    Show notes

    Show notes for Episodes 39 – February-March 2020

    1. Prevalence of colorectal cancer and advanced adenoma in patients with acute diverticulitis – GIE
    2. Pancreatic tuberculosis: A systematic review of symptoms, diagnosis and treatment – UEGJournal
    3. Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastro
    4. Risk of progression of Barrett’s esophagus indefinite for dysplasia: Meta-analysis – GIE
    5. AGA Clinical Pratice Update – Management of Pancreatic Necrosis – Gastro
    6. Establishing or Exaggerating Causality for the Gut Microbiome: Lessons from Human Microbiota-Associated Rodents – Cell
    7. Neutropenic Enterocolitis: Clinical Features and Outcomes – Dis Colon Rectum.
    8. Long-term Risk of Malignancy in Branch-Duct Intraductal Papillary Mucinous Neoplasms – Gastro
    9. Increased incidence and Mortality of Gastric Cancer in Immigrant Population from High to Low Regions of Incidence: Systematic Review – CGH
    10. AGA: Clinical Practice Guidelines on management of Gastric Intestinal Metaplasia – Gastro
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    GI Pearls January 2020 Feb 02, 2020
    Show notes

    Show notes for Episodes 38 – January 2020

    1. ASGE review of adverse events in colonoscopy – GIE
    2. Endoscopic or Surgical Myotomy in Patients with Idiopathic Achalasia – NEJM
    3. Relationship Between Recreational Marijuana Use and Bowel Function in a Nationwide Cohort Study – Am J gastro
    4. Circulating tumor DNA methylation profiles enable early diagnosis, prognosis prediction, and screening for colorectal cancer – Science TM
    5. Lactulose Breath Testing as a Predictor of Response to Rifaximin in Patients With Irritable bowel Syndrome With Diarrhea – AmJ Gastro
    6. Postinfectious IBS after Campylobacter infection – Am J Gastro
    7. Oral Curcumin no more effective than placebo in preventing recurrence of Crohn’s disease after surgery in RTC – CGH
    8. Hpylori – when treat when not to treat – Am J Gastro
    9. Long-Duration Oral Vancomycin to treat Cdiff in patients iwth IBD is associated with low rate of recurrence – Am J Gastro
    10. Masked bolus gluten challenge low in FODMAPs implicates nausea and vomiting as key shymptoms of exposure to celiac – AP&T
    11. Clinical and molecular features of post-colonoscopy colorectal cancers – CGH
    12. Simethicone use during gastrointestinal endoscopy: Position statement of the Gastroenterological Society of Australia – Journal of Gastro&Hep
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    GI Pearls December 2019 Dec 28, 2019
    Show notes

    Show Notes for December 2019 – Episode 37

    1. Assessment of Publication Trends of Systematic Reviews and RCTs – JAMA Int Med.
    2. Association between Hpylori exposure and decreased odds of EOE – CGH
    3. Effect of anti-Hpylori therapy on incidence of autoimmune diseases, – CGH
    4. AGA Practice Update on Surveillance for cancer in patients with PSC – Gastro.
    5. Screening for colorectal cancer in asymptomatic average-risk adults: ACP guideline – Annals of Int Med
    6. High intensity versus low intensity surveillance for patients with colorectal adenomas – Annals of Int med
    7. Infliximab-Tumor Necrosis Factor complexes Elicif formation of Anti-Drug Antibodies – Gastro
    8. Outcomes of Patients with IBD switched from maintenance therapy with a biosimilar to Remicade – CGH
    9. Lactose drives Enterococcus expansion to promote graft-versus-host disease – Science
    10. The association between dietary fiber deficiency and high-income lifestyle-associated diseses: Burkitt’s hypothesis revisited.
    11. Compared abilities of endoscopic techniques to increase colon adenoma detection rates – CGH
    12. Advanced imaging for detection and differentiation of colorectal neoplasia:ESGE Guidelines – Endoscopy
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    GI Pearls November 2019 Nov 24, 2019
    Show notes

    Show Notes for November 2019 – Episode 36

    1. Detection of Various Microplastics in Human stool – Annals of int Med
    2. Herpes Zoster in Tofacitinib: Risk is Further Increased with Glucocorticoids but not Methotrexate – Arthritis Care Res
    3. Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae – Cell
    4. Incidence of and Risk Factors for Hepatic Encephalopathy in a Population-Based Cohort of Americans – Hepatology Communications
    5. FFP transfusion in patients with cirrhosis and coagulopathy: effect on conventional coagulation tests and thrombomodulin-modified thrombin generation – J Hepatol.
    6. Effect of Chromoendoscopy in the proximal colon on Colorectal neoplasia detection in Lynch syndrome: A multicenter randomized controlled trial. – GIE
    7. Terminology, Molecular featuers, Epidemiology, and Management of Serrated Colon neoplaisa.
    8. Providing data for serrated polyp detection rate benchmarks – GIE
    9. Management of Nonvariceal Upper GI bleeding: Guideline recommendations from the International Consensus Group – Ann of Int Med
    10. Efficacy of Prophylactic Hemoclips in prevention of delayed post-polypectomy Bleeding in patients with large colonic polyps – Gastro
    11. Clip Closure Prevents Bleeding After Endoscopic resection of large colon polyps in a randomized trial – Gastro
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    GI Pearls October 2019 Oct 09, 2019
    Show notes

    Show Notes for Oct 2019 – Episode 35

    1. Appropriate therapeutic drug monitoring of Biologic agents for Patients with IBD – CGH
    2. The View from Europe – TDM – CGH
    3. Cold snare vs Heparin bridging and hot snare polypectomy in patients on anticoagulants with subcentimeter polyps. – Annals of int Med.
    4. High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength – JAMA
    5. Safety of Endoscopy in Heritable Connective Tissue Disorders – Am J Gastro
    6. ASGE guideline on screening and surveillance of Barrett’s esophagus – ASGE
    7. Prucalporide in Gastroparesis: A Randomized Placebo-controlled Crossover Study. – Am J Gastro
    8. Over-Utilization of Repeat Upper Endoscopy in patients with non-dysplastic Barrett’s esophagus – Am J Gastro
    9. Controlling fecal incontinence in women by performing anal exercises with biofeedback or loperamide: a randomized clinical trial. – Lancet Gastro &Hep
    10. Toshihiro Sugiyama Understanding the Current Evidence on Proton Pump Inhibitor Use and Bone Health – Gastro
    11. Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES):a randomised controlled trial – Lancet’
    12. Effect of Bismuth Subsalicylate vs Placebo on Use of Antibiotics Among Adult Outpatients With Diarrhea in Pakistan: A Randomized Clinical Trial. – JAMA Netw Open
    13. Association between soft drink consumption and mortality in 10 european countries. – JAMA
    14. Validation of Diagnostic and Performance Characteristics of the Wireless Motility Capsule in Patients with Suspected Gastroparesis – CGH
    15. Vedolizumab versus Adalimumab for Moderate-to-Severe Ulcerative Colitis – NEJM
    16. Ustekinumab for Ulcerative Colitis – NEJM
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    GI Pearls September 2019 Sep 05, 2019
    Show notes

    Show Notes for Sept 2019 – Episode 34

    1. Guidelines on management of cyclic vomiting syndrome – Neurogastro and Motility
    2. Drug-induced Acute-on-Chronic Liver Failure in Asian Patients – Am J Gastro
    3. The efficacy of split-dose bowel prep for polyp detection: Meta-analysis – Am J Gastr
    4. Drug-induced liver injury – types and phenotypes – NEJM
    5. ASGE guideline on the role of endoscopy for bleeding from Chronic radiation proctopathy – GIE
    6. Efficacy of budesonide orodispensible tablets as induction therapy for EOE – randomized trial – Gastro
    7. Endoscopic control of polyp burden and expansion of surveillance intervals in serrated polyposis syndrome – GIE
    8. Efficacy of FMT in IBS – Meta Analysis – Am J Gastr
    9. FMT in patients with PSC: Pilot clinical trial – Am J Gastr
    10. Nosocomial infections are frequent and negatively impact outcomes in hospitalized patients – Am J Gastro
    11. High immunogenicity of the PCV13 in immunocompromised adults with IBD – Am J Gastro
    12. Association of US News and World Ranking for GI and GIOperation With Patient Outcomes in Abdominal Procedures- JAMA Surgery
    13. JAMA Clinical Guidelines Synopsis – CRC screening
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