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    Science

    FirstTake on Pharma – Pharma News and Analysis Podcast

    The FirstTake – FirstWord’s editors discuss the latest pharma news and offer insights from industry experts and KOLs. Designed for the busy pharma industry professional. Visit us at beta.firstwordpharma.com to sign up for newsletters delivering timely news and event-driven physician intelligence.

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    Copyright: © 2021

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    Latest Episodes:
    The FirstTake Podcast – Previewing AACR Apr 07, 2022
    Show notes

    On this week’s episode FirstWord Pharma PLUS editors Virginia Li, Michael Flanagan and Simon King look ahead to the annual meeting of the American Association of Cancer Research (AACR) which is taking place this weekend in New Orleans.


    The FirstTake Podcast – The FDA faces up to a tricky ALS regulatory decision, Roche’s TIGIT setback and more… Mar 31, 2022
    Show notes

    On this week’s episode Virginia Li discusses the closely watched FDA AdCom meeting for Amylyx’s ALS therapy AMX0035, which saw experts vote narrowly against Amylyx having shown sufficient efficacy for the drug from a single clinical study. Simon King looks at two major clinical data announcements – for Almirall and Eli Lilly’s atopic dermatitis drug lebrikizumab and Roche’s potential cancer therapy tiragolumab. And FirstWord HealthTech’s Tina Tan highlights some notable trends in health tech venture capitalist investments during the first quarter of 2022, ahead of an exclusive live event for FirstWord HealthTech PLUS subscribers next week where she will provide a more comprehensive overview of VC activity.


    The FirstTake Podcast – A landmark cancer approval, Pfizer’s Arena deal delivers and the expert view on recent breast cancer developments Mar 24, 2022
    Show notes

    On this week’s episode editors Virginia Li and Simon King discuss FDA approval of the first novel checkpoint inhibitor for eight years – Bristol Myers Squibb’s LAG-3 inhibitor relatlimab – and evaluate positive data for Pfizer’s etrasimod, which it gained via December’s $6.7 billion acquisition of Arena Pharmaceuticals. In addition, FirstWord’s Michael Flanagan speaks to Adam Brufsky – professor of medicine at the University of Pittsburgh School of Medicine and associate chief for the school’s haematology/oncology division – to discuss the relevance of recent clinical and regulatory events that will impact the treatment of breast cancer.


    The FirstTake Podcast – Sanofi’s breast cancer hopeful fails to deliver Mar 17, 2022
    Show notes

    On this week’s episode FirstWord Pharma PLUS editors Virginia Li and Simon King discuss an unexpected corporate re-manoeuvring around Biogen and Eisai’s controversial Alzheimer’s drug Aduhelm and disappointing clinical data for Sanofi’s breast cancer drug amcenestrant. Simon also catches up with FirstWord HealthTech’s executive editor Tina Tan to find out about some recent oncologist surveys looking at the use of digital technologies to help combat pandemic-extended treatment waiting times and the mental wellbeing of cancer patients.


    The FirstTake Podcast – Gilead’s oncology strategy under the spotlight Mar 10, 2022
    Show notes

    On this week’s episode FirstWord Pharma PLUS editors Michael Flanagan and Simon King discuss why Gilead is getting flak for a positive cancer drug study, what’s gone wrong at bluebird bio and why the FDA has been so quick to expand approval of Bristol Myers Squibb’s Opdivo for the treatment of neoadjuvant lung cancer.


    The FirstTake Podcast – Where next for gene editing? Mar 03, 2022
    Show notes

    On this week’s episode FirstWord Pharma PLUS editors Virginia Li, Michael Flanagan and Simon King discuss key developments in the field of gene editing, the approval of Janssen and Legend Biotech’s Carvykti for multiple myeloma and whether interchangeability status will have a meaningful impact on future US market for Humira biosimilars.


    The FirstTake Podcast – Does a paradigm shift in breast cancer beckon? Feb 24, 2022
    Show notes

    This week FirstWord Pharma PLUS editors Michael Flanagan, Virginia Li and Simon King discuss confirmation of positive top-line data for AstraZeneca and Daiichi Sankyo’s Enhertu in HER2 ‘low’ breast cancer, the implications stemming from Amicus Therapeutics’ decision to abort a gene-therapy spin out and whether GlaxoSmithKline and Sanofi’s long-awaited COVID-19 vaccine has arrived too late to make a meaningful impact on the pandemic.


    The FirstTake Podcast – More questions than answers for Sage and Biogen Feb 17, 2022
    Show notes

    FirstWord Pharma PLUS editors Virginia Li and Simon King discuss Phase III clinical data for a new depression therapy being co-developed by Sage Therapeutics and Biogen, the FDA’s new - but also old – commissioner, Robert Califf, whose reappointment five years after he first held the role was confirmed by the US senate this week and whether Regeneron can make its multi-billion dollar eye-disorder therapy Eylea an even more compelling product for physicians.


    The FirstTake Podcast – AdCom upset for Lilly and Innovent Feb 10, 2022
    Show notes

    FirstWord Pharma PLUS editors Michael Flanagan, Virginia Li and Simon King discuss Eli Lilly’s attempt to bring price disruption to the US cancer immunotherapy market, Pfizer and Amgen’s future growth strategies and some new diabetes drugs to keep an eye on.


    The FirstTake Podcast – More Aduhelm fallout and JP Morgan wraps for another year Jan 13, 2022
    Show notes

    FirstWord Pharma PLUS editors Michael Flanagan, Virginia Li and Simon King discuss another setback for Biogen’s Alzheimer’s drug Aduhelm – this time at the hands of the Centres for Medicare and Medicaid Services – and highlight key takeaways from this week’s JP Morgan Healthcare Conference.


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