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    Education

    Finding Genius Podcast

    Podcast interviews with genius-level (top .1%) practitioners, scientists, researchers, clinicians and professionals in Cancer, 3D Bio Printing, CRISPR-CAS9, Ketogenic Diets, the Microbiome, Extracellular Vesicles, and more.

    Subscribe today for the latest medical, health and bioscience insights from geniuses in their field(s).

    Advertise

    Copyright: © Richard Jacobs

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    Latest Episodes:
    Extracellular Vesicle Endeavors—Veronika Kralj-Iglic Jan 14, 2020
    Show notes

    Veronika Kralj-Iglic, PhD is a physicist and Chair of Biomechanics at the University of Ljubljana, Slovenia who has done a variety of work in the field of medicine, classical physics, quantum physics, and orthopedics, but who says her favorite work has revolved around extracellular vesicle research. Why? According to Dr. Kralj-Iglic, it's because of the amount of potential that extracellular vesicles hold for the future of medicine and biology.

    "These little vesicles present a hope that maybe we will get to an understanding of the function of living systems," she says, commenting on the many questions that remain regarding the mechanism underlying the causes of cancer.

    She shares insight from years' worth of research, and touches on the following:

    • The details of two clinical trials involving EVs that she is currently working on
    • How cells have the ability to use parts of their cell membrane to create vesicles that help catalyze their actions
    • How the behavior of EVs is similar to artificial and biological membranes

    Health & Wellness – Nick Horowski, Holistic Health Professional and Founder of Evolution, Health & Fitness – Consider Your Health, and Improve it! Jan 13, 2020
    Show notes

    Nick Horowski, Holistic Health Professional and founder of Evolution, Health & Fitness (www.evo-health.com), delivers his thoughts on good health and offers tips for those who want to lead a healthier life. In this podcast, Horowski provides detailed information on holistic health and wellness, including the importance of nutrition in life.

    Horowski works as a consultant, health coach, and physical therapist. Horowski talks about his background and the reasons he was drawn to a career in health. He recounts how his childhood was filled with sports and health-conscious activities. Additionally, he saw the importance of eating healthy, from the garden, at a young age.

    Horowski describes how important it is to have balance of good sleep, good emotional and physical health, and diet. Horowski talks about the ways he connects with clients, some who may have troubling health issues already. As he states, what's important is to get his clients moving, and thinking, about the ways they can make improvements daily, from posture to activities, and more. Step by step is the key, taking steps toward your goal, even if they are small steps.

    Horowski talks about breaking old habits and patterns, and the importance of simple things, such as hydration and nutrition. Horowski explains how every client, every person, is different, and therefore any program for good health must be tailored to the individual.

    Wrapping up, Horowski discusses the spectrum of clients he works with, and their individual struggles and goals. Finally, Horowski talks about the keys to success in health goals, and how they can be achieved.

    In this podcast:

    • How to improve health through diet
    • How to live a holistic lifestyle
    • Is diet as important as exercise?

    Technology, Disease, and the Bacteria in Your Mouth—Priya Nimish Deo—Department of Oral Pathology and Microbiology, Bharati Vidyapeeth Dental College and Hospital in India Jan 13, 2020
    Show notes

    Researchers, physicians, and the layman alike are becoming more and more interested in understanding the role and function of the microbiome, and how it may be contributing to different states of health and disease.

    In the Department of Oral Pathology and Microbiology at Bharati Vidyapeeth Dental College and Hospital in India, assistant professor Priya Nimish Deo is collecting data and reviewing the current literature on the composition of the oral microbiome and how it may cause a variety of human diseases.

    Until the relatively recent development of a number of sequencing methods, only microbes capable of being cultured in the lab could be identified, but all of that is changing quickly.

    This will open the door to an unprecedented amount of information about the bacteria in our mouths and the diseases throughout our bodies.

    Tune in for the details on all of this and more, including:

    • How proteomics, metagenomics, and metabolomics differ from one another and are contributing to the identification and understanding of the oral microbiome
    • What useful functions microbes provide in the mouth
    • How microbial dysbiosis leads to changes in the function of microbes

    Certifiably Sound Sleep—Dr. Jonathan Greenberg—Sleep Certified Jan 13, 2020
    Show notes

    Stroke, heart attack, autoimmune diseases, weight gain and the inability to lose it, type 2 diabetes, Alzheimer's disease, and cancer: what do all of these have in common? According to Dr. Jonathan Greenberg, one of the foremost authorities in treating snoring and obstructive sleep apnea (OSA), as well as a growing body of evidence, they can all occur as a result of snoring or sleep apnea. This is a significant problem, especially considering the fact that tens of millions of people in the U.S. have sleep apnea, and most of them either don't know it or aren't being treated.

    Dr. Greenberg discusses the barriers to diagnosis and treatment when it comes to snoring and sleep apnea, and why so few people comply with what their doctors recommend. He also explains how his company, Sleep Certified, is making the process of receiving treatment more convenient for people, as well as encouraging awareness and education on the connection between sleep health, dental health, and overall health among dentists and physicians through a Sleep Certified training program that leads to multiple levels of certification. Contrary to popular belief, the CPAP machine is not the only option for those who snore and/or have sleep apnea.

    Press play to hear the full conversation and learn about all of this and more, including:

    • What type of treatment options are available aside from the CPAP machine, and how effective they're proving to be (including an oral appliance by Sleep Certified called Zyppah)
    • Why snoring and sleep apnea worsen with age, regardless of what kind of shape a person is in
    • What you could expect by seeing a dentist who has been certified at Level 9 of the Sleep Certified training program

    https://sleepcertified.com/


    Extracellular Vesicles Research: Dr. Dmitry Ter-Ovanesyan Explains the Exciting Potential and Challenges Ahead Jan 10, 2020
    Show notes

    After a discovery ten years ago showed that extracellular vesicles (EVs) contain RNA rather than just cell waste, Dr. Ter-Ovanesyan has studied these cellular products. This discussion explores:

    • Why it's significant that RNA is shown to exist outside of cellular boundaries.
    • What puzzles scientists need to solve to use EVs for new solutions in synthetic biology research.
    • The significant advances in health that EVs, also called exosomes, may offer, such as ways to address dementia, and already-developed technology such as detecting prostate cancer through finding EVs in the urine.

    Dr. Dmitry Ter-Ovanesyan is working as a post-doc at Harvard with the Wyss Institute in extracellular vesicle research. He's drawn to the great potential and challenges these exosomes offer scientists in solving multiple health issues.

    While EVs were discovered about 40 years ago, it wasn't until two studies published in 2007 announced that they contained RNA that the scientific community focused more energy their way. Dr. Ter-Ovanesyan was a student at the time and was immediately drawn to these RNA-carrying vesicles.

    He explains why RNA is so significant in the complexity of messages it might carry from one cell to another. He also describes the multiple challenges these exosomes present because of their heterogeneous nature and difficulties in isolating them. But he recounts the great potential they may offer, from offering doctors information about the brain or heart by supplying RNA information to RNA drug possibilities through synthetic biology research.

    For more information, see his contact information on the Wyss Institute page (https://wyss.harvard.edu/team/research-scientists-engineers/dima-ter-ovanesyan/_ and Harvard's Church Lab page (https://genetics.med.harvard.edu/lab/church/dter-ovanesyan). His publications are listed on PubMed as well.


    Musings of the Microbiome—Michael G. Surette—Professor, Division of Gastroenterology at McMaster University, Michael G. Surette Laboratory Jan 10, 2020
    Show notes

    As a gastroenterology specialist and professor at McMaster University, Michael G. Surette, PhD centers his work on a variety of aspects of the human microbiome, including its development and role in early life, what happens to it with age, and how it's related to chronic diseases such as those of the airway, as well as Crohn's, colitis, and IBS.

    On today's episode, Dr. Surette shares fascinating insight on the research he's conducting, what he's learned over the years, and the future of microbiome science.

    Tune in for the details on all of this and more, including:

    • How the interaction between microbes changes depending on physical, functional, and/or taxonomic closeness
    • Why it is difficult to define dysbiosis, and why it may never be possible
    • How environmental stimuli impact the microbiome
    • How to understand the relationship between the microbiome and the immune system, and why this understanding can help to explain why diseases like Crohn's and colitis are harder to overcome than infections like C. diff

    Learn more by visiting http://www.surettelab.ca/lab/.


    Physics Foundation – Wolfgang Smith, Scholar, Author, and Researcher in Mathematics and Physics – Physics, Answers to the Big Scientific Questions, and God Jan 10, 2020
    Show notes

    Wolfgang Smith, scholar, author, and researcher in mathematics and physics, presents an overview of his long and storied career in the sciences.

    From a young age, Smith was fascinated by the concept that physics could literally explain all that happens on Earth. Entering the prestigious Cornell University at the age of 15, Smith majored in physics, mathematics, and philosophy, and graduated at just 18 years old; and from there he began to question all that he had learned, and began to dig deeper. Smith provides an overview of the history and current state of physics. As he states, in regard to physics, we are approaching the end of an era, the end to the era of such scientific minds as Galileo and Newton.

    The scientific expert explains his thoughts on physics, expounding upon his views on testing and discovery, including the quantum realm and Newtonian physics. He discusses the philosophical thoughts of Rene Descartes. Continuing, he discusses the problems with the science that are not validated or supported by mathematics. He talks about beliefs in science, and the concept of enlightenment, citing examples of scientistic beliefs (those that are characterized by an exaggerated belief in the principles, and methods, of science). He states that we must differentiate between authentic science (the science that powers our technology, etc.) and the scientistic beliefs (science that the public knows about).

    Smith, unsatisfied with much of what contemporary science presented, sought to dig further, which culminated with his writing of the book, The Quantum Enigma. Smith discusses his book in detail and his arguments and findings that are written on the pages. As Smith states, the world that we perceive through our five senses is in fact very real. Logic is the basis of his thoughts… and he discusses how all of physics can be accomplished by working in the corporeal world and the physical world.

    Continuing, the scientific researcher discusses his specific thoughts on DNA and life, and the origins of organisms. Smith explains his thoughts on the biological world and the origin of life. As he states, the origin of everything is in God, and this is recognized. And he states that this belief will become the leading paradigm going forward, basing science on God the creator.


    Liquidizing Cancer and Cardiovascular Disease Diagnostics—Chamindie Punyadeera—Queensland University of Technology Jan 09, 2020
    Show notes

    Biopsies for the diagnosis of cancer are usually invasive and potentially dangerous. In addition, there's no guarantee that this method will even result in a sample of tumor cells, due to the heterogeneity of tumors.

    In today's episode, Chamindie Punyadeera from the Queensland University of Technology discusses a new non-invasive tool called a liquid biopsy to detect early cardiovascular disease and three types of cancers. Rather than relying upon a sample of tumor tissue retrieved through biopsy, this new tool uses saliva or blood.

    This is a cost-effective and less dangerous process for the patient, and it eliminates the chances of missing cancer cells that are there, but just weren't accessed by the needle. This method makes early detection of cancer in the premalignant stage possible, as well as the stratification of patients at diagnosis to determine the stage of cancer.

    Tune in for all the details on this and more, including:

    • What cell-free DNA is, where it's found, and how it can provide valuable information for cancer patients
    • How biomarkers in saliva may be used to identify patients at high risk of heart failure (such as those suffering from type 2 diabetes or obesity)
    • How this research will impact human health and medicine in the coming years

    Cross-Discipline Research on Bowel Disease: Dr. Paul Moayyedi Jan 09, 2020
    Show notes

    Gastroenterology specialist Dr. Paul Moayyedi describes why a network of researchers across Canada is studying causes and possibilities for relief for Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD). This podcast explores:

    • Why Dr. Moayyedi is a proponent of evidence-based medicine and how this directs the nature of his studies on bowel diseases and how gut bacteria affects health.
    • How the Imagine Network, a live cohort study involving at least 8,000 participants, is the appropriate way to tackle the complicated microbiome of the bowel.
    • What are roadblocks to current handling of Crohn's Disease and Ulcerative Colitis and how fecal transplants may be the best immediate solution.

    Dr. Moayyedi, Professor, Division of Gastroenterology at the Department of Medicine with MacMaster University, is principal investigator with Imagine Network, a study encompassing multiple disciplines, from gastroenterology specialists to psychiatrists, observing what changes in variables over time for IBS and IBD patients.

    While the study centers on bowel diseases, it looks at aspects in addition to the gut microbiome such as mental health, diet, and inflammation. Findings many benefit patients from Crohn's disease suffers to those testing for gastric cancer.

    He explains that the human gut, with the highest concentration of bacteria on the planet, is very difficult to study. Most diagnostics only offer a small snapshot. A colonoscopy, for example uncovers only a single element in gastric cancer, while many bowel diseases are for more complex. The Imagine Network approaches these diseases through multiple angles instead to get a fuller picture.

    One promising aspect of their work involves fecal transplants (which more accurately means the introduction of fecally-contaminated water), which changes the gut bacteria. They were the first to start randomized trials with fecal transplants and its effect on ulcerative colitis.

    They've found about a quarter of the patients found relief from the disease through these transplants. Dr. Moayyedi hopes they will encounter what drives such diseases through these studies.

    To get in contact or find out more, see www.imaginespor.com.


    Dirty Electricity: Diana Jabour Discusses How to Make a Healthier Home Jan 08, 2020
    Show notes

    Diana Jabour describes the "building biology" of our homes. She explains:

    • How bodily health connects to our building choices, from light bulbs to hard-wiring versus wireless systems.
    • How electromotive forces, or EMF pollution, and electromagnetic radiation dangers affect the quality of our sleep and anxiety levels.
    • What are some solutions, from quick and easy devices like foil screens to better design choices from the ground up.

    Diana Jabour, Environmental and Electromagnetic Radiation Specialist and owner of Jabour Environmental, believes we can be CEOs of our health. Her mother modeled research-driven selections alongside common sense for healthy choices in food and materials, and Jabour continues practicing what she learned from this inspiring figure.

    When she noticed her own family experiencing troubling symptoms after moving into a new home, she began researching. She then attended the Building Biology Institute in Santa Fe and Jabour added to her already solid understanding of EMF pollution and electromagnetic radiation dangers.

    She discusses the ways our homes handle the four elements of building biology: air quality, water quality, lighting quality, and electromagnetic fields.

    Jabour offers the good news that we can control our space and she explains how, from techniques to ensure we are sleeping in electric fields that are close to nature to understanding why "anything that says 'smart' is stupid," and how we can better protect ourselves from EMF pollution and electromagnetic radiation dangers. Finally, she describes how she does a walk-through for her clients and types of solutions she typically recommends.

    For more about these issues, see her company's web site at https://www.jabourenvironmental.com/;


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