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Copyright: © Richard Jacobs
This podcast describes a cutting-edge application of analytical chemistry. When you listen, you will learn:
Laura-Isobel McCall, Assistant Professor at the University of Oklahoma, specializes in chemical cartography of host-microbe interactions. She runs the McCall Lab, where they practice the application of analytical chemistry to map disease-causing microbes in mammalian organ systems.
The McCall Lab explores the interaction between pathogens, the microbiome, and the host to develop drugs that are capable of metabolism modulation. Through metabolomics testing and chemical cartography, Dr. McCall's lab is working on compounds to counter the effects of pathogens such as parasites. Much of their work focuses on neglected diseases, often potentially deadly, such as trypanosoma cruzi, which is present in the United States.
Dr. McCall explains how locating and mapping microbes with 3D technology and metabolomics testing opens up an understanding of how these pathogens function. This has led to identifying how important timing is in treating against the effects of such pathogens: the extent of tissue damage and the eventual dormant stage of a parasite are factors of time, for example. Furthermore, developing compounds to bolster how the host deals with the energy demand of the pathogen is more effective than simply targeting the pathogen.
Future work of the lab includes applying these techniques to other types of pathogens, improving the compounds to help patients, and connecting this work to other location-centered diseases.
For more information, see the McCall Lab page at http://mccall-lab.oucreate.com/ and find them on twitter as @LabMccall.
Jordan Stern, MD, Founder & CEO of BlueSleep, a successful sleep health and wellness company, talks about the diagnosis of sleep apnea and his company's solutions for better sleep.
Dr. Stern is an award-winning head and neck surgeon, and a New York Times bestselling author. He is board-certified in otolaryngology and sleeps medicine. Dr. Stern discusses his background and the massive epidemic of sleep apnea, a condition of which most people do not even know they have. The sleep expert and researcher discusses various sleep conditions including hypopnea, which is shallow breathing, an abnormally low respiratory rate. The condition is regularly defined by a significantly decreased amount of air movement into the lungs, so much so that it can cause oxygen levels in the blood to drop. Hypopnea is often due to partial obstruction of the upper airway. Dr. Stern describes how the oxygen in your blood drops when you suffer from hypopnea.
The sleep doctor discusses the various risk factors for sleep apnea, the primary one being weight gain. He states that as we age, many people tend to gain weight, and this weight gain can often bring about sleep apnea. Continuing, Dr. Stern explains how BlueSleep can provide testing and treatment for various sleep disorders, as he discusses snoring causes and effect and snoring treatment in detail. The sleep doctor goes on to discuss CPAP (continuous positive airway pressure) devices, oral appliances, snoring causes and effect, snoring treatment and more.
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In this podcast, Dr. Abramson will explain:
Dr. Mark Abramson is sleep apnea and TMJ specialist in Northern California. After facing an injury in his teen years, his resolve to pursue healing strengthened and he has spent 40 years developing a treatment program that brings together the mind-body connection in dentistry.
In this podcast, he describes the complex ways the mouth and jaw, two main centers of growth, interact within the muscular-skeletal complexes of our upper body. The extent to which we are mouth breathers, how our tongue grows, and what types of orthodontics we've had an all affect TMJ pain we may experience or whether we struggle with sleep apnea.
Dr. Abramson describes the numerous medical evaluations patients will undergo before they seek TMJ treatments or sleep apnea treatment. Because pain is multi-dimensional with primary and referred pain, patients struggle with understanding causes. Dr. Abramson uses a comprehension of these interplays to develop special splints and sleep apnea appliances as well as cranial osteopathic manipulation to treat patients.
For more information, see Dr. Abramson's office web site: https://www.drtmjsleepapnea.com/
For information on practitioners that use his Oasys system, see: http://oasyssleep.com/
Most of us go to the doctor about once a year, or at least we should in order to get a routine check-up and some blood tests done. This visit allows for an important dialogue about our health, including information about our biochemistry such as how much sodium, potassium, or glucose is in our system at the time of the appointment. However, it can be hard to keep up with the changes the doctor recommends because it's easy to forget about them when life seems to get in the way.
What if there was a way to monitor your own personal biochemistry in real-time? You had a salad for lunch instead of a donut, and you went for a walk after work instead of sitting on the couch; if you could get the biochemical data associated with those lifestyle changes in real-time, you might be more likely to continue implementing healthful changes and paying attention to the way your body responds to different stimuli.
Until now, the technology that would allow for this simply hasn't existed.
On today's episode, CEO of Profusa, Ben Hwang, talks about a new and affordable technology that puts the power of biochemical data in the hands of the user. Unlike other biochemical sensors that don't last longer than a couple of days or weeks, the Profusa sensor can last for years, which means it's affordable and more convenient for you. Interested in learning more?
Tune in to discover:
Learn more at https://profusa.com/.
Cyanobacteria are photosynthetic microorganisms that release toxins, and they're also the building blocks of life itself. Under healthy conditions, the environment in which cyanobacteria live serves as a system of checks and balances wherein cyanobacteria do not overpopulate. When this system of checks and balances is disturbed, such as by human intervention, changes in temperature, or any number of other factors which influence the rate at which cyanobacteria grow, the toxins they produce end up dominating the whole ecological sphere in which they exist, and continuously change the chemical and biological conditions in the water.
This overpopulation is happening globally in nearly every place you can find water, whether in the sea, lakes, or reservoirs for irrigation, and it's having devastating consequences for environmental and human health.
BlueGreen Technologies Ltd has developed the first-ever solution to dealing with large-scale algal blooms and restoring the health and use of bodies of water around the world. Eyal Harel is the CEO and co-founder of this company, and he joins the podcast to explain how their products work, and why they show so much more promise than any solution which has come before it.
By tuning in, you will learn:
Learn more by visiting http://bgtechs.com/about/.
Janet Bennett, author and sleep expert, provides an overview of her comprehensive sleep program (ijustwanttosleep.com) that is helping people find a way to get better, more restful sleep.
Bennett is an experienced, successful Speech Pathologist in private practice who is passionate about helping people end their suffering and find new pathways to quality sleep. Bennett explains that snoring is a definite sign that a person's sleep is not ideal. Snoring indicates mouth breathing which may be preventing one's body from going into that deep REM sleep that we all need to feel refreshed come morning.
Bennett explains how snoring can lead to sleep apnea, and she talks about the importance of educating people about the signs. While many people seem to think they cannot breathe well through their nose, and thus resort to mouth breathing, the truth is—they can, and simply need to relearn or train themselves on how to nose breath again. Bennett explains how her program trains people to put the tip of their tongue at a certain spot on the palette, which can help them immensely. The good sleep entrepreneur talks about CPAP (continuous positive airway pressure) machines, and provides information about the changes in the industry.
Bennett discusses mouth breathing in detail, and she expounds upon the various tongue exercises that anyone can use to retrain their tongue to hold itself at the roof of the mouth, which enables you to breathe naturally through the nose. She talks about snoring causes and effects, snoring treatment, and the hundreds of snoring sufferers she has worked with through the years. And her work produces results, which she discusses. Bennett provides some impressive stats regarding improvement and the results seen after people utilize her program.
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Around the world, there are thousands of variations on religion and faith-based practices, and religion itself can happen on many levels—within your own self, within your family, within your church, within different churches of the same sect, and so on. Today's episode is the first in a new series on religions around the world.
Richard Jacobs will explore all aspects of the continuum on which religions and faith fall, and dive into a number of topics with guests who are eager to share their personal experiences with faith and religion. Tune in for a discussion with Jay Wesley Richards, Research Assistant Professor in the Busch School of Business at the Catholic University of America, and New York Times bestselling author.
You will discover:
For over 30 years, Ted Schroeder has been involved in the sales, marketing, and development of antibiotics, and he currently serves as the CEO of Nabriva Therapeutics. He joins the podcast today to discuss the current work being done at Nabriva, which involves the development of a new class of IV antibiotics for the treatment of community-acquired pneumonia in adults—the first of its kind in the US in over two decades.
The second product Nabriva is working on has been around for nearly four decades but has never been available in the US, and it's been shown to be effective in tackling complicated urinary tract infections and multidrug-resistant strains of bacteria. These antibiotics could limit or altogether eliminate the need for hospital stays for many people. To learn more about the work being done, tune in.
You'll discover the details of all this and more, including:
For more information, visit https://www.nabriva.com/.
Ronald C. McGlennen, M.D., President & Medical Director of Access Genetics, delivers an interesting overview of oral issues, discussing the microbiome and bacteria.
In addition to his work with Access Genetics, Dr. McGlennen is also the Associate Professor of Pathology at the University of Minnesota Medical School. Dr. McGlennen is board certified in Anatomic and Clinical Pathology, and by the American Board of Medical Genetics with a Specialty in Clinical Molecular Genetics as well.
The internationally-recognized expert in Molecular Biology and Genetics discusses his thoughts on the oral microbiome, periodontal disease, and conditions of the mouth. Dr. McGlennen states that the microbiome has earned its place as an organ in our bodies and must be recognized for its role that is central to good health. Changes in the gut flora can provide answers to intestinal health, and the microbiome truly holds many answers to medical issues. In regard to bad bacteria, he states, much of it comes from our environment—intimate contact, foods, surfaces, etc. He explains how, over time, due to age and lack of exercise etc., we move into a state of dysbiosis, which is essentially a microbial imbalance on or inside the body—such as an impaired microbiota. Dr. McGlennen discusses the ways in which our microbiome can be affected, and he delves into an overview of periodontal disease and its causes. He discusses disease markers and pathogens, and the indicators of disease.
The doctor provides intricate detailed information on gum disease, plaque build up, bad bacteria in the mouth, other specific detrimental issues of the mouth, and mouth bacteria treatment. He discusses the eleven bacteria that make up the 'quantitative DNA analysis' and how they can utilize this information to understand cumulative bacterial load, and to grasp how to best provide treatments and therapies.
Dr. McGlennen has published over 70 important scientific articles and book chapters and he is the distinguished editor of five journals.
In this podcast:
Wynand De Beer, independent researcher and philosopher, specializing in Hellenic philosophy and Patristic theology, discusses philosophy; socio-political discourse; and metaphysics, the specific branch of philosophy that pertains to the nature of existence, being, and the world.
De Beer is a member of the Russian Orthodox Church and he has written numerous articles for Orthodox publications and various websites, penned under his Orthodox name, Vladimir de Beer. He is the author of From Logos to Bios: Evolutionary Theory in Light of Plato, Aristotle, and Neoplatonism.
De Beer discusses his thoughts on philosophical, socio-political, theological, and metaphysical issues. He explains that much of the mindset regarding issues of this nature has been lost due to rationalism, secular humanism, and materialism. He talks about the important works of others who have come before him, such as Albert Camus, the French Algerian philosopher, author, and journalist.
De Beer talks in detail about some of the areas of his latest book, analyzing big issues from various chapters, from well being and love, to good vs evil, to consciousness, and the three manifestations of consciousness. Digging deeper, De Beer provides an analysis of gender, as it relates to our current and historical interpretations.
He states that the traditional understanding of man and woman, male and female, must function as polar opposites in order to constitute the reality that we live in. He provides an interesting account of the views on feminism, and the militant forms of feminism, and male chauvinism… all of which must be rejected as wrong, as they present an imbalanced view. There is no subordination or domination he states.
De Beer explains that the views and function of gender and sexuality, etc. are often taken to the extreme, perhaps as a form of rebellion, but ultimately too extreme. De Beer continues, discussing the details of other areas of his book, including a salient discussion on modern liberalism. He discusses his views on the immortality of the soul, referencing early Greek mythology from significant voices such as Plato.
The influential author and philosopher provides further details on his thoughts on politics and conflict. He discusses his next book, currently titled, Origins, and expounds upon some of the topics he will touch upon in the upcoming work.
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