Evidence Based Hair

Latest Episodes:

Season 1, Episode 11 (Scarring Alopecia - Frontal Fibrosing Alopecia and Lichen Planopilaris) Apr 18, 2022

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STUDIES REFERENCED

FRONTAL FIBROSING ALOPECIA & REPIGMENTATION:

Barreto TM et al (starts at 3:18). Atypical frontal fibrosing alopecia presentation in a male patient associated with spontaneous reversal of canities. J Eur Acad Dermatol Venereol. 2022 Mar 12

Defo D et al Repigmentation pilaire enbordure d’une alopecie frontale fibrosante. [Hair darkening close to a patch of frontal fibrosing alopecia]. Ann Dermatol Venereol 2006;133: 799–801

Pastor-Nieto et al. Localized grey hair repigmentation (canities reversal) in patients with frontal fibrosing alopecia. J Eur Acad Dermatol Venereol 2021; 35: e408–e410.

COSMETIC SURGERY AND RISK OF FRONTAL FIBROSING ALOPECIA:

Pham et al (starts at 9:00). The Association of Frontal Alopecia with a History of Facial and Scalp Surgical Procedures. Skin Appendage Disord. 2022 Jan;8(1):13-19.

Kossard and Shiell. Frontal fibrosing alopecia developing after hair transplantation for androgenetic alopecia. Int J Dermatol. 2005 Apr;44(4):321-3.

Chiang YZ et al. Lichen planopilaris following hair transplantation and face-lift surgery Br J Dermatol. 2012 Mar;166(3):666-370.

HAIR TRANSPLANT SURGERY FOR PATIENTS WITH FFA:

Vano-Galvan S et al (starts at 14:30). Hair transplant in frontal fibrosing alopecia: A multicenter review of 51 patients. J Am Acad Dermatol. 2019 Sep;81(3):865-866.

Arasu et al (starts at 22:13). Scalp reduction surgery does not reactivate frontal fibrosing alopecia: A case report. Dermatol Ther. 2022 Mar 16;e15451.

LICHEN PLANOPILARIS AND CHECKPOINT INHIBITORS

Garcia-Melendo C et al (starts at 38:59). Extensive lichen planopilaris as exclusive lichenoid reaction secondary to pembrolizumab in a patient with metastatic melanoma. Dermatol Ther. 2022 Feb 17;e15388.

Uthayakumar AK et al. Severe progressive scarring pembrolizumab-induced lichen planopilaris in a patient with metastatic melanoma. Australas J Dermatol. 2021 Aug;62(3):403-406.

Cogen et al. Lichen planopilaris associated with pembrolizumab in a patient with metastatic melanoma. JAAD Case Rep . 2018 Jan 16;4(2):132-134.

Dominguez-Santas M et al. Avelumab-induced lichen planopilaris, a novel association. Int J Dermatol. 2021 Oct;60(10):e414-e416.

Season 1, Episode 10 (Telogen Effluvium, Tinea Capitis, Trichotillomania) Apr 11, 2022

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REFERENCES CITED IN THIS EPISODE (and TIME STAMP)

TELOGEN EFFLUVIUM

Monari et al (starts at 4:20). Post-SARS-CoV-2 Acute Telogen Effluvium: An Expected Complication. J Clin Med. 2022 Feb 24;11(5):1234.

Muller-Ramos P et al. Post-COVID-19 hair loss: prevalence and associated factors among 5,891 patients. Int J Dermatol 2022 Jan 26.

Guarnieri G et al (starts at 9:07). Relationship between hair shedding and systemic inflammation in COVID-19 pneumonia. Ann Med. 2022;54(1):869-874.

Wong-Chew RM et al (starts at 13:11). Symptom cluster analysis of long COVID-19 in patients discharged from the Temporary COVID-19 Hospital in Mexico City. Ther Adv Infect Dis. 2022 Jan 11;9:20499361211069264.

Fernandez-de-Las-Penas et al. Female Sex Is a Risk Factor Associated with Long-Term Post-COVID Related-Symptoms but Not with COVID-19 Symptoms: The LONG-COVID-EXP-CM Multicenter Study. J Clin Med. 2022 Jan 14;11(2):413.

Ali MD (starts at 18:49). Proton pump inhibitors' use and risk of iron deficiency anaemia: a systematic review and meta-analysis. Curr Rev Clin Exp Pharmacol. 2022 Mar 7.

TRICHOTILLOMANIA AND PEDIATRIC EMOTIONAL HEALTH

Wang et al (starts at 24:29). Trichotillomania occurs during the COVID-19 pandemic in an adolescent. World J Pediatr. 2022 Feb 28;1-2.

Saunders NR et al. Utilization of Physician-Based Mental Health Care Services Among Children and Adolescents Before and During the COVID-19 Pandemic in Ontario, Canada. April 2022 JAMA Pediatrics.2022 Apr 1;176(4):e216298.

Racine N et al. Global Prevalence of Depressive and Anxiety Symptoms in Children and Adolescents During COVID-19: A Meta-analysis JAMA Pediatr. 2021;175(11):1142-1150.

Pathoulas et al. Cross-sectional survey examining skin picking and hair pulling disorders during the COVID-19 pandemic. J Am Acad Dermatol. 2021 Mar;84(3):771-773.

Öner Ü. Children with trichotillomania in COVID-19 outbreak. J Cosmet Dermatol. 2021;20(7):1967–8.

TINEA CAPITIS

Salah NB et al (starts at 31:19). Erythema nodosum in patients with kerion of scalp. Clin Exp Dermatol. 2021 Dec;46(8):1577-1578.

Blake T et al. Erythema nodosum - a review of an uncommon panniculitis. Dermatol Online J. 2014 Apr 16;20(4):22376.

Kumar P and Pandhi D (starts at 41:09). Role of Trichoscopy in the Management of Tinea Capitis in Two Infants: A Case Report. J Cutan Aesthet Surg. Oct-Dec 2021;14(4):443-445.

Season 1, Episode 9 (Alopecia Areata and Androgenetic Alopecia) Apr 04, 2022

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STUDIES HIGHLIGHTED

ALOPECIA AREATA

King B et al (starts at 3:27). Two Phase 3 Trials of Baricitinib for Alopecia Areata. N Engl J Med. 2022 Mar 26.

Fenentinos P et al (starts at 16:24). Assessing the role of stressful life events in the induction and recurrence of alopecia areata: a case-control study. J Am Acad Dermatol. 2022 Mar 24;S0190-9622(22)00526-6.

Macbeth A et al (starts at 21:14). The associated burden of mental health conditions in alopecia areata: A population-based study in UK primary care. Br J Dermatol. 2022 Feb 14.

Senna M et al (starts at 29:06). Predictors of Quality of Life in Patients with Alopecia Areata. J Invest Dermatol 2022 Mar 21;S0022-202X

ANDROGENETIC ALOPECIA

Ghafoor R et al (starts at 39:15). Association of androgenetic alopecia and severity of coronavirus disease 2019. J Cosmet Dermatol. 2022 Mar;21(3):874-879.

Baghani M et al (starts at 40:57). Androgenetic alopecia and COVID-19: Is there a clinical connection? J Cosmet Dermatol . 2022 Feb;21(2):420-425.

Veskovic D et al (starts at 42:04). Association of androgenetic alopecia with a more severe form of COVID-19 infection. Ir J Med Sci. 2022 Mar 23;1-6.

Season 1, Episode 8 (Minoxidil in Breastfeeding, Prepubertal Hair Loss, Trichorrhexis nodosa) Mar 28, 2022

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Recording of the Evidence Based Hair Podcast for the March 28, 2022 issue. STUDIES HIGHLIGHTED Trueb RM et al (starts at 3:27). Minoxidil-induced hypertrichosis in a breastfed infant. J Eur Acad Dermatol Venereol. 2022 Mar;36(3):e224-e225. Gangal et al (starts at 7:08). Mask-associated acquired trichorrhexis nodosa of the beard. JAAD Case Rep. 2022 Mar;21:101-102. Trueb RM et al. Prepubertal pattern hair loss (starts at 13:38) Clin Exp Dermatol. 2022 Jan;47(1):173-175.):24-30 Katayama S et al (starts at 17:00). Rapidly Progressive Hair Loss May Be the Only Sign of Syphilis. Am J Med 2022 Feb 22;S0002-9343(22)00130-9. Kolla et al (starts at 32:34). Dermatologists' knowledge of dermoscopic features in hair and nail disorders. J Eur Acad Dermatol Venereol. 2022 Feb 11. Rutnin S et al (starts at 37:32)). Variation of Hair Follicle Counts among Different Scalp Areas: A Quantitative Histopathological Study. Skin Appendage Disord. 2022 Jan;8(1):24-30. Xie et al (starts at 42:27). Hair shaft miniaturization causes stem cell depletion through mechanosensory signals mediated by a Piezo1-calcium-TNF-α axis. Cell Stem Cell 2022 Jan 6;29):

Season 1, Episode 7 (Scarring Alopecia) Mar 21, 2022

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STUDIES HIGHLIGHTED

FFA STUDIES

Dubin C et al (starts at 2:50). Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement. J Am Acad Dermatol. 2022 Mar;86(3):551-562. doi: 10.1016/j.jaad.2021.05.016

Starace et al (starts at 12:31). Clinical and Dermoscopic Approaches to Diagnosis of Frontal Fibrosing Alopecia: Results From a Multicenter Study of the International Dermoscopy Society. Dermatol Pract Concept. 2022 Jan 1;12(1):e2022080

Rayinda T et al (starts at 17:25). Clinical characteristics of male frontal fibrosing alopecia: a single-centre case series from London, UK. Br J Dermatol. 2022 Jan;186:195-197

LPP STUDIES

Moussa A et al (starts at 21:51). Treatment of lichen planopilaris with baricitinib: A retrospective study. J Am Acad Dermatol. 2022 Feb 21;S0190-9622(22)00338-3

Mostafa N et al (starts at 25:24). Mycophenolate mofetil and lichen planopilaris: systematic review and meta-analysis. J Dermatolog Treat . 2022 Feb;33(1):369-372.

FOLLICULITIS DECALVANS STUDIES

Iorizzo M et al (starts at 27:25). Refractory folliculitis decalvans treated with adalimumab: a case series of 23 patients. J Am Acad Dermatol 2022 Mar 1;S0190-9622(22)00358-9.

CCCA STUDIES

Roche FC et al (starts at 33:01). Association of type 2 diabetes with central centrifugal cicatricial alopecia: A follow-up study. J Am Acad Dermatol. 2022 Mar;86(3):661-662.

Collins MS et al (starts at 37:45). Increased risk of vitamin D deficiency and insufficiency in Black patients with central centrifugal cicatricial alopecia. J Am Acad Dermatol . 2022 Feb 15;S0190-9622(22)00272-9.

Powe et al. Vitamin D-binding protein and vitamin D status of black Americans and white Americans. N Engl J Med 2013 Nov 21;369(21):1991-2000.

Brown L et al. The vitamin D paradox in Black Americans: a systems-based approach to investigating clinical practice, research, and public health - expert panel meeting report. BMC Proc . 2018 May 9;12(Suppl 6):6.

Season 1, Episode 6 (Telogen Effluvium, Tinea Capitis, Trichotillomania, Traction Alopecia) Mar 14, 2022

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STUDIES HIGHLIGHTED IN THIS EPISODE

TELOGEN EFFLUVIUM

Lytvyn et al (starts at 2:15). Comparing the frequency of isotretinoin-induced hair loss at

Season 1, Episode 5 (Androgenetic Alopecia and Alopecia Areata) Mar 07, 2022

Show notes

STUDIES HIGHLIGHTED IN THIS EPISODE

Qui Y et al (starts at 2:41). Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia. Acta Derm Venereol. 2022 Feb 8;102:adv00645

Gupta AK et al (starts at 8:38). Relative Efficacy of Minoxidil and the 5-alpha Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients: A Network Meta-analysis. JAMA Dermatol. 2022 Feb 2:e215743

Plante J (starts at 23:13). Perifollicular inflammation and follicular spongiosis in androgenetic alopecia. J Am Acad Dermatol 2022Feb;86(2):437-438.

Qiu et al (starts at 28:04). Efficacy assessment for low-level laser therapy in the treatment of androgenetic alopecia: a real-world study on 1383 patients. Lasers Med Sci. 2022

Yale K et al (starts at 33:53). A year in review: A cross-sectional study of alopecia areata and risk of COVID-19 infection, hospitalization, and mortality from March 2020 -February 2021 Int J Dermatol. 2022 Mar;61(3):e81-e83.

Lee MM (starts at 38:10). Alopecia areata following COVID-19 vaccination: vaccine-induced autoimmunity? Int J Dermatol. 2022 Feb

Bardazzi et al (starts at 39:04). New insights on alopecia areata during COVID-19 pandemic: when infection or vaccination seems to play a role. J Cosmet Dermatol. 2022 Feb 188.

Scollan M et al (starts at 41:08). Alopecia areata after SARS-CoV-2 vaccination JAAD Case Rep. 2022 Feb;20:1-5.

Harries M et al (starts at 43:42). The epidemiology of alopecia areata: a population-based cohort study in UK primary care. Br J Dermatol. 2022 Feb;186(2):257-265.

Gutierrez Y et al (starts at 49:38). Alopecia areata in the United States: a ten-year analysis of patient characteristics, comorbidities, and treatment patterns. Dermatol Online J. 2021 Oct 15;27(10)

Season 1, Episode 4 (Safety & Side Effects of Hair Loss Treatments: Spironolactone, Tofacitinib, Doxycycline, Minoxidil, Methotrexate, Laser Hair Removal) Feb 28, 2022

Show notes

STUDIES HIGHLIGHTED IN THIS EPISODE

Korbi M et al (starts at 1:58). Topical minoxidil-induced paresthesia. Dermatol Ther. 2022 Jan 20;e15328.

Panigrahi M et al (starts at 9:37). A recent surge of doxycycline-induced pill esophagitis during the corona virus disease 2019 (COVID-19) pandemic. Indian J Gastroenterol Jan 2022

Panigrahi M et al (starts at 14:45). A recent surge of doxycycline-induced pill esophagitis during the corona virus disease 2019 (COVID-19) pandemic. Indian J Gastroenterol Jan 2022

Bommareddy et al (starts at 18:48). Association of Spironolactone Use With Risk of Cancer: A Systematic Review and Meta-analysis. JAMA Dermatol 2022 Feb 9

Ytterberg SR et al (starts at 25:13). Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis. N Engl J Med. 2022 Jan 27;386(4):316-326. doi:

Snast I et al (starts at 37:45). Paradoxical Hypertrichosis Associated with Laser and Light Therapy for Hair Removal: A Systematic Review and Meta-analysis Am J Clin Dermatol 2021 Sep;22(5):615-624

Season 1, Episode 3 (Scarring Alopecia) Feb 21, 2022

Show notes

STUDIES HIGHLIGHTED IN THIS EPISODE FRONTAL FIBROSING ALOPECIA STUDIES Maghfour J et al (starts at 3:09). The Association between Frontal Fibrosing Alopecia, Sunscreen, and Moisturizers: A Systematic Review with a Meta-Analysis. J Am Acad Dermatol. 2022 Jan 21 (online). Sun et al (starts at 6:36). Characterization and Treatment of Prominent Facial Vasculature in the Setting of Frontal Fibrosing Alopecia J Am Acad Dermatol 2022 Jan 5; (online) Lobato-Berezo et al (starts at 11:05). Frontal fibrosing alopecia in men: A multicenter study of 39 patients. J Am Acad Dermatol. 2022 Feb;86(2):481-484. Bernardez C et al (starts at 13:57). Beard loss in men with frontal fibrosing alopecia. J Am Acad Dermatol. 2022 Jan;86(1):181-183. LICHEN PLANOPILARIS STUDIES Gardellini A et al (starts at 20:26). Lichen planopilaris-like eruption in chronic myeloid leukemia patient during treatment with nilotinib as second-line therapy. J Oncol Pharm Pract. 2022 Jan 17 (online) Lahouel et al. Nilotinib-induced lichen planopilaris. Int J Dermatol. 2022 Jan;61(1):e37-e38. CENTRAL CENTRIFUGAL CICATRICIAL ALOPECIA STUDIES Jamerson et al (starts at 30:00). Gene expression profiling suggests severe, extensive central centrifugal cicatricial alopecia may be both clinically and biologically distinct from limited disease subtypes Exp Dermatol. 2022 Jan 10 FOLLICULITIS DECALVANS STUDIES Moussa A et al (starts at 34:58). Successful treatment of folliculitis decalvans with baricitinib: A case series. Australas J Dermatol. 2022 Jan 22.

Season 1, Episode 2 (Telogen Effluvium, Trichotillomania, Tinea Capitis) Feb 14, 2022

Show notes

STUDIES REFERENCED IN THIS EPISODE

TELOGEN EFFLUVIUM - HAIR LOSS FOLLOWING COVID 19

STUDY 1 (starts at 3:09 ): Lopez-Leon S et al. More than 50 Long-term effects of COVID-19: a systematic review and meta-analysis. medRxiv. 2021 Jan 30;2021.01.27.21250617.

STUDY 2 (starts at 4:47): Muller-Ramos P et al. Post-COVID-19 hair loss: prevalence and associated factors among 5,891 patients. Int J Dermatol 2022 Jan 26.

STUDY 3 (starts at 10:32 ): Fernandez-de-Las-Penas et al. Female Sex Is a Risk Factor Associated with Long-Term Post-COVID Related-Symptoms but Not with COVID-19 Symptoms: The LONG-COVID-EXP-CM Multicenter Study. J Clin Med. 2022 Jan 14;11(2):413.

TELOGEN EFFLUVIUM IN CHILDREN

STUDY 4 (starts at 12:45 ): Thomas et al. Single Centre Retrospective Review ofNutritional Deficiencies Associated With Telogen Effluvium in the Paediatric Population in Canada. J Cut Med Surg Jan 2022 (online)

TRICHOTILLOMANIA

STUDY 5 (starts at 18:44) : Moattari et al. Adverse psychocutaneous effects of prescription stimulant use and abuse: A systematic review. J Dtsch Dermatol Ges. 2022 Jan;20(1):7-15.

STUDY 6: (starts at 23:12); Vaccaro et al. Erosive pustular dermatosis of the scalp as local complication of trichotillomania. J Cosmet Dermatol. 2022 Jan 8. 2022 Jan 8

TINEA CAPITIS

STUDY 7 (starts at 27:51): Friedland et al. Epidemiologic features and risk of scarring in pediatric patients with kerion celsi. Pediatr Dermatol. 2022 Jan 13. doi: 10.1111/pde.14916. Online ahead of print.

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