Depresh Mode with John Moe

Latest Episodes:

Maureen Johnson Became Friends with Her Anxiety Monster Dec 01, 2025

Show notes

Maureen Johnson loves mysteries. Loves reading classic detective fiction and loves writing mystery stories, which young readers have been gobbling up for years. Some of Maureen’s stories feature teenage sleuth Stevie Bell, who, besides having a knack for solving cold cases, deals with an anxiety disorder. It’s not all there is to Stevie, of course, but it’s definitely there and she has to manage it on an ongoing basis. Maureen tells us about Stevie and about her own recent anxiety mystery when she was suddenly whomped by a massive wave of anxiety that would not go away and severely affected her life for quite a while. Faced with that mystery, Maureen got to work gathering clues to figure it out, ultimately finding many effective techniques, including to fighting the anxiety monster (which she visualizes as Gossamer, the big red furry monster from Bugs Bunny cartoons) but welcoming it, getting to know it, and finding out what made it tick. She also got some lab work done, which pointed to a pronounced iron problem that was fixable.

Thank you to all our listeners who support the show as monthly members of Maximum Fun.

Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.

Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

Help is available right away.

The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

Crisis Text Line: Text HOME to 741741.

International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh

A Holiday Family Survival Mini-sode Nov 26, 2025

Show notes

Yes, the holidays are upon us. Getting together with family can be a wonderful, loving experience. It can also be a lot. There can be old grudges, chafing at family roles, the specter of politics might play in. We’re here to help. In This Family is a podcast produced by our host, John Moe, for Nexus Family Healing, a mental health nonprofit based in the Twin Cities. It’s all about the connections between family and mental health.

In this miniature episode, that show’s host, Dr. Michelle K. Murray goes over some good ways to manage your boundaries, take care of yourself, and have a good time. Dr. Murray is a licensed family and marriage therapist and CEO of Nexus Family Healing. Give this short episode a quick listen in the car on the way to see family and give In This Family a listen. You’ll find episodes with some Depresh Mode favorite guests like Maria Bamford and Gary Gulman and some new voices you’ll enjoy.

Thank you to all our listeners who support the show as monthly members of Maximum Fun.

Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

Help is available right away.

The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

Crisis Text Line: Text HOME to 741741.

International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh

Esmé Weijun Wang’s Mind Convinced Her She Was Dead and In the Afterlife Nov 24, 2025

Show notes

Cotard’s delusion, also known as Cotard’s syndrome, is an extremely rare condition where the patient believes that they are actually dead. For the bestselling author Esmé Weijun Wang, Cotard’s came along after she had already been traveling a difficult road that involved schizoaffective disorder along with a host of other mental health issues. While experiencing Cotard’s, Esmé urgently told her husband that he was dead too and so was their dog. She believed, was certain, that the life she was experiencing was kind of a simulation where she had to prove herself worthy of a second chance and not an eternity in Hell. We also hear about the shocking way Yale handled Esmé’s mental health and about the trauma very early in childhood that she thinks led to the complex PTSD that fueled a lot of her mental health challenges.

Thank you to all our listeners who support the show as monthly members of Maximum Fun.

Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

Help is available right away.

The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

Crisis Text Line: Text HOME to 741741.

International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh

Is Your Mental Health Diagnosis an Identity or Something More Meaningless? Nov 17, 2025

Show notes

You may find the charges in this episode jarring: depression is not the result of a chemical imbalance, SSRIs aren’t necessarily antidepressants, and the term you use for your mental health condition isn’t scientifically valid. Sarah Fay, author of Pathological: The True Story of Six Misdiagnoses says it’s dangerous to identify with your diagnosis because it’s kind of made up and it blocks your path to recovery.
A doctor told her she was “an anorexic” when Sarah was 12 years old, even though she didn’t meet many of the criteria for anorexia. Sarah embraced the identity, taking on the behaviors and habits of a person with that eating disorder. Later in life, she was diagnosed with five more disorders, each time embracing the tag, all while her mental health deteriorated. Finally, another doctor said he didn’t know what was the matter with her and that gave Sarah some peace and a chance to focus on feeling better. She saw her mental makeup as something not bound by the names of disorders in the Diagnostic and Statistical Manual used by mental health professionals. While she still takes meds and sees a therapist and a psychiatrist, Sarah has come to believe that everyone’s focus needs to be on recovery rather than focusing on the limitations borne of terms she says are way too subjective and that don’t stand up to scientific scrutiny.

Thank you to all our listeners who support the show as monthly members of Maximum Fun.

Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

Help is available right away.

The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

Crisis Text Line: Text HOME to 741741.

International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh

The Personal Side of Huge Cuts to Addiction, Suicide Prevention, and Mental Health Programs Nov 10, 2025

Show notes

Over half the employees at the Substance Abuse and Mental Health Services Administration (SAMHSA) who were there in January are now gone, include 12 of the 17 senior leaders. SAMHSA is in charge of distributing and administering mental health programs around the country and the cuts to both staffing and to the programs the agency serves have meant many programs addressing addiction and suicide prevention being severely hobbled or shutting down altogether. In turn, that means fewer people getting help and more people suffering. O. Rose Broderick, Disability and Healthcare Reporting Fellow at Stat, joins us to explain the cuts, why they may be happening, and the extremely fragile state of these programs in America today. Rose also share her own connection to mental health, the struggles her own family has endured, and why all mental health stories are, at their heart, personal matters.

Thank you to all our listeners who support the show as monthly members of Maximum Fun.

Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

Help is available right away.

The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

Crisis Text Line: Text HOME to 741741.

International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh

Seasonal Affective Disorder and Why It Sucks So Bad Nov 03, 2025

Show notes

When we went looking for information on the condition known as seasonal affective disorder, or SAD, one of the first things we noticed was that some people aren’t even calling it that anymore. The website for the National Alliance on Mental Illness (NAMI), for instance, uses the term “major depressive disorder with a seasonal pattern”, which means an acronym of MDDWASP. Here at Depresh Mode, we’re perfectly fine referring to it as “mud wasp”. On this episode of the show, we talk with NAMI’s chief medical officer, Dr. Ken Duckworth, about how it’s similar to and different from traditional depression and what one could do to deal with it. With Ken, we discuss the less common and less understood spring and summer variety of MDDWASP. We also hear from Joy and Christina from our Preshies group on Facebook about their experiences.

Thank you to all our listeners who support the show as monthly members of Maximum Fun.

Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

Help is available right away.

The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

Crisis Text Line: Text HOME to 741741.

International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

The Depresh Mode newsletter is available twice a week. Subscribe for free and stay up to date on the show and mental health issues. https://johnmoe.substack.com/

John’s acclaimed memoir, The Hilarious World of Depression, is now available in paperback. https://us.macmillan.com/books/9781250209566/thehilariousworldofdepression

Find the show on X @depreshpod and Instagram @depreshpod.

John is on X @johnmoe.

Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh

Is Whiteness a Mental Health Problem? Dr. Jonathan Mathias Lassiter Thinks So. Oct 27, 2025

Show notes

It’s a question we ask a lot on this show: do you have a mental health problem or is the problem actually rooted in the world you live in? Psychologist Dr. Jonathan Mathias Lassiter says contemporary society lives under three different assumptions: there’s not enough to go around, kill or be killed, and us versus them or divide and conquer and this results in people valuing individualism, competition, and materialism. This way of living, he says, is a result of white dominance or whiteness and it is a distortion of the way humans are meant to live and therefore leads to things like racism, sexism, homophobia, and the brutality of human beings to one another. Dr. Lassiter, author of How I Know White People Are Crazy and Other Stories says whiteness is not a mental health disorder but it is a mental health problem that we all need to face. Dr. Lassiter tells his own story, growing up with a chronic illness, gay, and Black in the South and eventually earning his PhD. in psychology. As he came to understand psychology and the way the world works, he noticed the impact of society’s built-in obstacles on his own mental health journey and among the students and clients he has helped.

Thank you to all our listeners who support the show as monthly members of Maximum Fun.

Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

Help is available right away.

The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

Crisis Text Line: Text HOME to 741741.

International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh

Is the U.S. Government Going To Take Away Your Antidepressants? Oct 20, 2025

Show notes

Robert F. Kennedy, Jr., the Secretary of Health and Human Services, clearly does not like SSRIs (selective serotonin reuptake inhibitors), the most popular form of antidepressant on the market. They’re used by millions of Americans on a daily basis. He has tried to tie SSRIs to school shooters despite a lack of evidence to that effect. He has suggested that it’s harder to go off SSRIs than it is to quit heroin. It’s not. Molly Olmstead, a reporter for Slate who has been covering this story closely, says that this does not mean that the government is about to try to ban SSRIs and leave patients without the medicines that may be keeping them alive. But she explains that yes, we are in the midst of a very active anti-SSRI PR campaign by Kennedy and his supporters in the so-called Make America Healthy Again movement and that campaign could presage a much more aggressive set of actions.

Thank you to all our listeners who support the show as monthly members of Maximum Fun.

Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

Help is available right away.

The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

Crisis Text Line: Text HOME to 741741.

International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh

P.E. Moskowitz on Whether Your Mind is Broken or the World Is Oct 13, 2025

Show notes

During the violent Charlottesville protests of 2017, journalist and author P.E. Moskowitz was only a few feet away when Heather Heyer was killed by an attacking motorist. 16 years earlier, P.E. was in middle school Spanish class a couple blocks from the World Trade Center during the 9/11 attacks. The trauma contributed to panic attacks and, finally, a mental breakdown. As they got their life back together, P.E. began to question a lot of conventional wisdom. Were they mentally ill to have such a breakdown or were they responding appropriately to enormous trauma in a difficult world? Are we looking at potential cures when we should be looking at coping or better yet coming up with ways to stop the horrors from ever taking place? They also questioned the role of drugs in mental health treatment. In the book Breaking Awake: A Reporter's Search for a New Life, and a New World, Through Drugs and in this intriguing interview, P.E. explains how they look at drugs - both the prescription and street varieties - as tools that can be used positively or negatively, to help or harm. And that patients are owed a lot more options than a shortcut to SSRIs or Adderall in their quest to feel better.

Thank you to all our listeners who support the show as monthly members of Maximum Fun.

Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

Help is available right away.

The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

Crisis Text Line: Text HOME to 741741.

International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh

Kendall Toole Gets Knocked Down, Never Knocked Out Oct 06, 2025

Show notes

If you are one of the many subscribers to the Peloton exercise/media network, you may already be familiar with Kendall Toole. For many years, she was one of the stars of Peloton, exhorting users to push themselves harder, sweat more, and pursue their goals. In those cases, Kendall was positive, cheerful, always with a smile and kind words. But people are complicated and the truth is that Kendall has faced many mental health issues over the course of her life, including depression, anxiety, OCD, and suicidality. She’s in a better place now (she considers her conditions to be not cured but managed) but in an honest and moving interview, Kendall tells of her brush with suicidal ideation in college, her long stretch of depression that followed, and the words of her father that helped pull her toward a better place. You’re knocked down, he said, but never knocked out.

Thank you to all our listeners who support the show as monthly members of Maximum Fun.

Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

Help is available right away.

The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

Crisis Text Line: Text HOME to 741741.

International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh

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