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    Health & Fitness

    Depresh Mode with John Moe

    Join host John Moe (The Hilarious World of Depression) for honest, relatable, and, yes, sometimes funny conversations about mental health. Hear from comedians, musicians, authors, actors, and other top names in entertainment and the arts about living with depression, anxiety, and many other common disorders. Find out what they’ve done to address it, what worked, and what didn’t. Depresh Mode also features useful insights on mental health issues with experts in the field. It’s honest talk from people who have been there and know their stuff. No shame, no stigma, and more laughs than you might expect.

    Advertise

    Copyright: © 2021 Maximum Fun

    • Apple Podcasts
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    Latest Episodes:
    BONUS CONTENT PREVIEW: Depresh Mode: The Game Show Mar 20, 2025
    Show notes

    In this bonus content edition of Depresh Mode, We’re joined by some Maximum Fun all-stars for some very light-hearted and delightfully competitive games that are as informative as they are silly.

    Our competitors:

    • Justin McElroy of My Brother, My Brother, and Me, Adventure Zone, and Sawbones
    • Hal Lublin of Tights & Fights and We Got This
    • Laura Swisher, senior producer overseeing about a million Max Fun podcasts

    Who will win the game Antidepressant, Pokemon, or State Fair Food? Who will emerge victorious in Google Scholar or Member of Parliament/Funkadelic? Can our panel tell the difference between an emo band lyric, a quote from The Simpsons’ Moe, or a line heard on Depresh Mode? Tune in and find out!

    Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh


    John Moe helps kick off MFD Spring Break Mar 17, 2025
    Show notes

    It’s not MaxFunDrive without a wild kickoff spectacular! Former real-life VJ and host of MTV's Spring Break 1999, Dave Holmes, takes your favorite MaxFun hosts through some wacky ‘90s- and Spring Break-themed mini games!!

    Featuring: Dave Holmes, Jeremy Bent, Oscar Montoya, Dimitry Pompée, Tom Lum, Ellen Weatherford, Alex Schmidt, Brenda Snell, Drea Clark, Alonso Duralde, Dan McCoy, Jordan Morris, Manolo Moreno, Ella Hubber, Caroline Roper, Ella McLeod, John-Luke Roberts, Justin McElroy, Clint McElroy, Mike Cabellon, Sierra Katow, Hal Lublin, Danielle Radford, John Moe, Christian Dueñas, Christian Duguay.

    Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh


    J. Kenji Lopez-Alt on Food, Booze, Weed, Anxiety, Depression, and Living a Healthy Life Mar 17, 2025
    Show notes

    The alcohol, says J. Kenji Lopez-Alt, came about in young adulthood, when it solved persistent social anxiety and made him the life of the party. As Kenji found tremendous success in food writing and restaurateuring, he found that he couldn’t really make it through the day without downing between two and five drinks. This wasn’t hard to pull off in the food business, surrounded by booze and a culture that heartily encouraged its consumption. Kenji found that, as is so often the case with mental health, that the reality of the condition didn’t match the drunken messy stereotype: his work wasn’t harmed, he had strong relationships and a family. It’s just that he was an addict. Finally, just a few months ago and in his mid-40’s, he decided to get sober.

    This episode marks the kick-off of the 2025 Max Fun Drive! Check out the fun thank you gifts and become a member of Max Fun!

    Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

    Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.

    Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

    Help is available right away.

    The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

    Crisis Text Line: Text HOME to 741741.

    International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

    Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh


    Checking in With Friends During Scary Times: Paul F. Tompkins, Ana Marie Cox, and Gary Gulman Mar 10, 2025
    Show notes

    Maybe you’re one of those people who dreads even looking at the news these days, with stories of layoffs, tariffs, upheaval in foreign policy, and a lack of knowledge as to where this is all going and what it might mean for the future of America and the world. It’s a tumultuous time. When things are chaotic, it can be good to check in with one’s friends and that’s what Depresh Mode does this week. We have conversations of commiseration, of humor, and of hope with comedian and actor Paul F. Tompkins, pundit and writer Ana Marie Cox, and comic and author Gary Gulman.

    Thank you to all our listeners who support the show as monthly members of Maximum Fun.

    Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

    Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.

    Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

    Help is available right away.

    The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

    Crisis Text Line: Text HOME to 741741.

    International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines


    Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh


    Heavy Substance Use, Heavy Depression, and Heavy Metal with Randy Blythe from Lamb of God Mar 03, 2025
    Show notes

    Lamb of God is a very popular heavy metal band with Grammy nominations, gold records, and a huge headbanging following. Randy Blythe, front man for the band and author of a new book, Just Beyond the Light, is in recovery from drugs and alcohol and tells stories of finding sobriety, including how it was pretty easy to stay sober while on an Australian vacation surrounded by koalas but a lot harder once he returned to the States and the old patterns and routines of his life. Randy also talks about surviving a panic attack and finding better health through acts of service to others.

    Thank you to all our listeners who support the show as monthly members of Maximum Fun.

    Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

    Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.

    Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

    Help is available right away.

    The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

    Crisis Text Line: Text HOME to 741741.

    International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

    Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh


    Microdosing with James Fadiman and Jordan Gruber Feb 24, 2025
    Show notes

    Microdosing involves taking very small amounts of psychedelic substances such as LSD or psilocybin, maybe seven to twelve percent of a regular dose. It’s not enough to “trip out” but enough, proponents say, to yield very positive results, especially in terms of treating depression that hasn’t responded well to other methods. The catalog of extensive clinical, scientific trials about the practice of microdosing is pretty limited but James Fadiman and Jordan Gruber have collected what scientific material there is plus a great number of anecdotal reports in their new book, Microdosing for Health, Healing, and Enhanced Performance. They tell us about the potential of microdosing for mental health, migraines, long covid, and athletics.

    Thank you to all our listeners who support the show as monthly members of Maximum Fun.

    Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

    Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.

    Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

    Help is available right away.

    The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

    Crisis Text Line: Text HOME to 741741.

    International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines


    Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh


    Surviving Trauma and Having a Few Laughs with Ophira Eisenberg Feb 17, 2025
    Show notes

    Ophira Eisenberg once believed that everyone had a trauma quota, a maximum amount of hardship that a person would face in life and once that mark was hit, nothing bad would ever happen again. It was a way of comforting herself after a car accident at age eight that seriously injured Ophira and killed her friend. Turns out that’s not how life works and Ophira still had cancer and a miscarriage to deal with later on. Ophira joins us for a wise and actually very funny conversation about trauma, being an “awful patient”, and healing.

    Thank you to all our listeners who support the show as monthly members of Maximum Fun.

    Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

    Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.

    Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

    Help is available right away.

    The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

    Crisis Text Line: Text HOME to 741741.

    International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines


    Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh


    Your Vagus Nerve: Key to Depression Relief? / Actor-Writer Kit Williamson Feb 10, 2025
    Show notes

    Would you get a device the size of a Nilla wafer implanted in your body if it meant relief from treatment-resistant depression? There are big advances being made in vagal nerve stimulation therapy, a process by which electrical impulses are fed into a patient’s vagus nerve to alleviate depression that hasn’t responded to more common treatments. We take a look at the science, the breakthroughs, and why your insurance might be more likely to cover it.

    Then we have an interview with actor and writer Kit Williamson, creator of the new series Unconventional, about living with depression, living with anxiety, and bringing those struggles to television comedy.

    Thank you to all our listeners who support the show as monthly members of Maximum Fun.

    Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

    Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.

    Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

    Help is available right away.

    The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

    Crisis Text Line: Text HOME to 741741.

    International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

    Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh


    Neko Case on Pain, Neglect, Music, and Confidence Feb 03, 2025
    Show notes

    The cover of Neko Case’s memoir features a young Neko in a swimsuit she says she wore for six months straight and she’s accompanied by a drawing of a big spiky-toothed monster who she says is there to protect her. The invention of such monsters can feel necessary when one’s parents are unavailable, simply not physically present, or, in the case of her mother, faking their own death only to reappear a year and a half later. Neko talks about the trauma of her childhood, what music meant then and as she grew up, and how she’s shouldered and managed the pain ever since.

    Thank you to all our listeners who support the show as monthly members of Maximum Fun.

    Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

    Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.

    Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

    Help is available right away.

    The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

    Crisis Text Line: Text HOME to 741741.

    International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines


    Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh


    Dr. Emily Nagoski on Sex, Long Term Relationships, and Depression Jan 27, 2025
    Show notes

    Sex is not always an easy topic to discuss. Issues like how to get what you want, how to make sure your partner is getting what they want, these are delicate conversations and often intimidating ones as well. Add in issues like depression and anxiety for one or more of the people involved and it becomes more complex still. Fortunately, we have Dr. Emily Nagoski with us who is an expert on sex and how to talk about it. She’s the author of the new book, Come Together: The Science (and Art!) of Creating Lasting Sexual Connections and she’s here to offer some practical, workable advice.

    Thank you to all our listeners who support the show as monthly members of Maximum Fun.

    Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

    Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.

    Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

    Help is available right away.

    The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

    Crisis Text Line: Text HOME to 741741.

    International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines


    Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh


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