CGA-IGC Podcast Series

Latest Episodes:

Episode 3: S.5 Ep.3 Patterns of germline and somatic testing after universal tumor screening for Lynch syndrome: A clinical practice survey of active members of the CGA-IGC Jun 20, 2022

Show notes

This episode is hosted by Thomas (T.J.) Slavin, M.D.,FACMGG, PhD and features Rachel Hodan, MS, CGC, Genetic Counselor & Clinical Assistant Professor at Stanford University, Cancer GeneticsClinic and Kimberly Perez, MD, Gastrointestinal Medical Oncologist & Assistant Professor of Medicine, Dana Farber Cancer Institute.

Together they discuss “Patterns of germline and somatic testing after universal tumor screening for Lynch syndrome: A clinical practice survey of active members of the CGA-IGC” which was published in the Journal of Genetic Counseling and found here: https://pubmed.ncbi.nlm.nih.gov/35218578/
The CGA Clinical Practice Survey 2022: Universal Germline Testing for Colorectal Cancer is currently open and CGA-IGC members are invited to participate. Check your inbox for the survey link.
This episode was recorded on June 1st, 2022 and reflects expert opinion at the time of the recording.

Episode 2: S.5 Ep.2 EUS - based Pancreatic Cancer Surveillance in BRCA1/BRCA2/PALB2/ATM Carriers without a Family History of Pancreatic Cancer May 18, 2022

Show notes

This episode is hosted by Thomas (T.J.) Slavin, M.D.,FACMGG, PhD and features Bryson Katona, M.D., PhD, Director, Gastrointestinal Cancer Genetics Program & Assistant Professor of Medicine at the Hospital of the University of Pennsylvania; and Jessica Long, MS, CGC, Division of Hematology–Oncology, Department of Medicine at the University of Pennsylvania. Together they discuss the article “EUS-based Pancreatic Cancer Surveillance in BRCA1/BRCA2/PALB2/ATM Carriers Without a Family History of Pancreatic Cancer” which was published in Cancer Prevention Research and found here: https://pubmed.ncbi.nlm.nih.gov/34341011/
Studies mentioned during the podcast
https://clinicaltrials.gov/ct2/show/NCT02478892?term=NCT02478892&draw=2&rank=1
https://clinicaltrials.gov/ct2/show/NCT02000089?term=CAPS5&draw=2&rank=1

https://clinicaltrials.gov/ct2/show/NCT04970056?term=PRECEDE&draw=2&rank=4
This episode was recorded on April 25th, 2022 and reflects expert opinion at the time of the recording.

Episode 1: S.5 Ep.1 Creating Breast and Gynecologic Cancer Guidelines for Transgender Patients With BRCA Mutations Mar 24, 2022

Show notes

This episode is hosted by Maureen May, MS, CGC and features Bronwyn Bedrick, M.D., M.S.C.I., who is a Gynecology and Obstetrics Resident Physician at Johns Hopkins Hospital. Together they discuss the article “Creating Breast and Gynecologic Cancer Guidelines for Transgender Patients With BRCA Mutations,” which was published in Obstetrics & Gynecology and found here: https://pubmed.ncbi.nlm.nih.gov/34735408/
Resources mentioned during the podcast

WPATH Standards of Care (free to download in many different languages): Standards of Care - WPATH World Professional Association for Transgender Health (https://wpath.org/publications/soc)
WPATH Provider Directory: WPATH World Professional Association for Transgender Health (https://www.wpath.org/provider/search?)
UCSF Guideline: Guidelines for the Primary and Gender-Affirming Care of Transgender and Gender Nonbinary People | Gender Affirming Health Program (ucsf.edu) (https://transcare.ucsf.edu/guidelines)

This episode was recorded on March 3, 2022 and reflects expert opinion at the time of the recording.

Episode 22: S.4 Ep.5 Impact of Patients' Companions on Clinical Encounters Between Black Patients and Their Non-Black Oncologists Sep 14, 2021

Show notes

This episode is hosted by Dr. Thomas Slavin (T.J.) and features Amy K. Otto, PhD, who is a Research Assistant Professor in the Department of Public Health Sciences at the University of Miami Miller School of Medicine. Together they discuss the article “Impact of Patients' Companions on Clinical Encounters Between Black Patients and Their Non-Black Oncologists,” which was published in JCO Oncology Practice and found here: https://pubmed.ncbi.nlm.nih.gov/33411574/
This episode was recorded on August 26, 2021 and reflects expert opinion at the time of the recording.

Episode 21: S.4 Ep.4 Prospective Statewide Study of Universal Screening for Hereditary Colorectal Cancer: The Ohio Colorectal Cancer Prevention Initiative Aug 16, 2021

Show notes

This episode is hosted by Dr. Thomas Slavin (T.J.) and features Rachel Pearlman, MS, CGC, who is a Licensed, Certified Genetic Counselor and Assistant Professor in the Department of Internal Medicine at The Ohio State University Comprehensive Cancer Center. Together they discuss the article “Prospective Statewide Study of Universal Screening for Hereditary Colorectal Cancer: The Ohio Colorectal Cancer Prevention Initiative,” which was published in JCO Precision Oncology and found here: https://pubmed.ncbi.nlm.nih.gov/34250417/
This episode was recorded on August 10, 2021 and reflects expert opinion at the time of the recording.

Episode 20: S.4 Ep. 3 Naproxen Chemoprevention Promotes Immune Activation in Lynch Syndrome Colorectal Mucosa Apr 12, 2021

Show notes

This episode is hosted by Dr. Thomas Slavin (T.J.) and features Dr. Eduardo Vilar-Sanchez. Dr. Vilar-Sanchez is a medical oncologist at MD Anderson Cancer Center. Together they discuss “Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa,” which was published in Gut and found here: https://pubmed.ncbi.nlm.nih.gov/32641470/

This episode was recorded on March 26, 2021 and reflects expert opinion at the time of the recording.

Episode 19: S.4 Ep. 2 Phenotypic Differences in Juvenile Polyposis Syndrome With or Without a Disease-causing SMAD4/BMPR1A Variant Mar 17, 2021

Show notes

This episode is hosted by Dr. Thomas Slavin (T.J.) and features Dr. Bryson Katona and Dr. Suzanne MacFarland. Dr. Katona is a gastroenterologist at Penn Medicine and Dr. MacFarland is an oncologist in the Children’s Hospital of Philadelphia. Together they discuss their recent publication, “Phenotypic Differences in Juvenile Polyposis Syndrome With or Without a Disease-causing SMAD4/BMPR1A Variant,” published in Cancer Prevention Research and found here: https://pubmed.ncbi.nlm.nih.gov/33097490/

This episode was recorded on January 25, 2021 and reflects expert opinion at the time of the recording.

Episode 18: S.4 Ep. 1 Eflornithine plus Sulindac for Prevention of Progression in Familial Adenomatous Polyposis Feb 16, 2021

Show notes

This episode is hosted by Dr. Thomas Slavin (T.J.) and features Dr. Carol Burke, a gastroenterologist at the Cleveland Clinic. They discuss a study of combination therapy to delay disease progression in patients with familial adenomatous polyposis, recently published in The New England Journal of Medicine, found here: https://pubmed.ncbi.nlm.nih.gov/32905675/
This episode was recorded on January 12, 2021 and reflects expert opinion at the time of the recording.

S.3 Ep.6 Hereditary diffuse gastric cancer: updated clinical practice guidelines Oct 20, 2020

Show notes

The sixth episode, hosted by Dr. TJ Slavin, features Dr. Sonia Kupfer, a gastroenterologist at University of Chicago and former CGA-IGC president. They discuss the updated clinical practice guidelines for hereditary diffuse gastric cancer that were recently published online in Lancet Oncology, found here: https://pubmed.ncbi.nlm.nih.gov/32758476/ .
This episode was recorded on September 21, 2020, and reflects expert opinion at the time of the recording.

S.3 Ep. 5 Cancer prevention with aspirin in hereditary colorectal cancer (Lynch Syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial Oct 19, 2020

Show notes

The fifth episode, hosted by CGA-IGC Council Member Dr. Swati Patel, features Sir John Burn, who is a professor of clinical genetics at Newcastle University, and Dr. Toni Seppälä, who is a GI surgeon from University of Helsinki currently conducting a research fellowship at Johns Hopkins University. They discuss recently updated data from the CAPP2 study of aspirin chemoprevention in individuals with Lynch syndrome that was published in Lancet this summer, found here: https://pubmed.ncbi.nlm.nih.gov/32534647/.
This episode was recorded on September 22, 2020, and reflects expert opinion at the time of the recording.

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