Best Medicine

Latest Episodes:

6 - Team Sports, Making Sense, Pet Dog Blood Donors, Board Games Sep 02, 2026

Show notes

Joining Kiri Pritchard-McLean this week is comedian Josh Pugh who makes the case for the life lessons learnt in Team Sports. Professor Julia Simner explores how our senses shape reality and talks to Kiri about a new pair of AI glasses that are helping people with dementia, Veterinary Ophthalmologist Dr Serena Maini champions the dogs helping to save other dogs' lives through blood donation, and writer Tim Clare rolls the dice for Board Games.

Best Medicine is your weekly dose of laughter, hope and incredible medicine. Award-winning comedian Kiri Pritchard-McLean is joined by a funny and fascinating panel of comedians, doctors, scientists, experts and historians to celebrate medicine's inspiring past, present and future.

Each week Kiri challenges a panel of experts and a comedian to make a case for what they think is 'the best medicine'. Each guest champions anything from world-changing science or an obscure invention to an everyday treatment, an uplifting worldview, an unsung hero or a futuristic cure.

Whether it’s groundbreaking surgery, seaweed underwear, AI glasses to help people with dementia, horse therapy, sports, revolutionary gene therapy for Huntington’s disease or yesterday’s rubbish becoming tomorrow’s medicines - it’s always something worth celebrating.

Hosted by Kiri Pritchard-McLean

Featuring: Tim Clare, Dr Serena Maini, Josh Pugh and Professor Julia Simner

Written by Edward Easton, Mel Owen, Kiri Pritchard-McLean and Ben Rowse

Producer: Tashi Radha

Executive Producer: Ben Worsfield

Theme tune composed by Andrew Jones

A Large Time production for BBC Radio 4

5 - Seaweed Underwear, Bubbles, Saunas Aug 26, 2026

Show notes

Joining Kiri Pritchard-McLean this week is entrepreneur Alex Perry who champions seaweed underwear inspired by a personal mission to improve women's health. Professor Eleanor Stride returns with bubbles (again) in the fight against everything from cancer to antimicrobial resistance, and comedian Kate Cheka turns up the heat in defence of saunas.

Each week Kiri challenges a panel of experts and a comedian to make a case for what they think is 'the best medicine', and each guest champions anything from world-changing science or an obscure invention to an everyday treatment, an uplifting worldview, an unsung hero or a futuristic cure.

Hosted by Kiri Pritchard-McLean

Featuring: Kate Cheka, Alex Perry and Professor Eleanor Stride

Written by Edward Easton, Jordan Gray, Frances Keyton, Mel Owen, Kiri Pritchard-McLean, Ben Rowse and Rhys Thorne

Producer: Tashi Radha

Executive Producer: Ben Worsfield

Theme tune composed by Andrew Jones

A Large Time production for BBC Radio 4

4 - Fighting, Gene Therapy for Huntington’s Disease, Plants Aug 19, 2026

Show notes

Joining Kiri Pritchard-McLean this week is comedian Stephen Bailey who explains how fighting transformed his confidence. Professor Ed Wild shares a groundbreaking gene therapy that can treat Huntington's disease for the first time, and Professor Alessandra Devoto explores how plants like basil could help unlock future treatments for liver fibrosis.

Hosted by Kiri Pritchard-McLean

Featuring: Stephen Bailey, Professor Alessandra Devoto and Professor Ed Wild

Written by Edward Easton, Jordan Gray, Frances Keyton, Kiri Pritchard-McLean, Ben Rowse and Rhys Thorne

Producer: Tashi Radha

Executive Producer: Ben Worsfield

Theme tune composed by Andrew Jones

A Large Time production for BBC Radio 4

3 - Horses, Breaking Bad News, Reels Aug 12, 2026

Show notes

Joining Kiri Pritchard-McLean this week is CEO and Founder of Devon Healing Horsemanship Louise Broadway, who champions how horses can help people for whom talking therapies haven’t worked. Intensive Care Doctor Matt Morgan argues there's more to Breaking Bad News than simply delivering it, and comedian Mel Owen shares how Instagram Reels helped lead her to not one but two life-changing diagnoses.

Hosted by Kiri Pritchard-McLean

Featuring: Louise Broadway, Dr Matt Morgan and Mel Owen

Written by Edward Easton, Frances Keyton, Jordan Gray, Mel Owen, Kiri Pritchard-McLean and Ben Rowse

Producer: Tashi Radha

Executive Producer: Ben Worsfield

Theme tune composed by Andrew Jones

A Large Time production for BBC Radio 4

2 - Reformer Pilates, Persistence, Free Flaps Aug 05, 2026

Show notes

Joining Kiri Pritchard-McLean this week is comedian Jamie MacDonald who stretches the limits with Reformer Pilates, married couple Dr Lindsey Fitzharris and Adrian Teal who pitch the power of Persistence, and Wing Commander Poonam Valand who has Kiri in stitches with surgical Free Flaps.

Each week Kiri challenges a panel of experts and a comedian to make a case for what they think is 'the best medicine'. Each guest champions anything from world-changing science or an obscure invention to an every-day treatment, an uplifting worldview, an unsung hero or a futuristic cure.

Hosted by Kiri Pritchard-McLean

Featuring: Dr Lindsey Fitzharris, Jamie MacDonald, Adrian Teal and Wing Commander Poonam Valand

Written by Mel Owen, Kiri Pritchard-McLean and Ben Rowse

Producer: Tashi Radha

Executive Producer: Ben Worsfield

Theme tune composed by Andrew Jones

A Large Time Production for BBC Radio 4

1 - Rubbish, Home Births, Collaboration Jul 29, 2026

Show notes

Joining Kiri Pritchard-McLean this week is comedian Michelle Wolf who reflects on home births, Professor Stephen Wallace explains how old plastic bottles can be transformed into a form of Dopamine that can be used to treat Parkinson’s disease, and Dr Matt Clarke from the Institute of Cancer Research and Great Ormond St Hospital demonstrates the power of medical collaboration in helping to identify and treat brain tumours.

Hosted by Kiri Pritchard-McLean

Featuring: Dr Matt Clarke, Professor Stephen Wallace and Michelle Wolf

Written by Edward Easton, Jordan Gray, Kiri Pritchard-McLean and Ben Rowse

Producer: Tashi Radha

Executive Producer: Ben Worsfield

Theme tune composed by Andrew Jones

A Large Time production for BBC Radio 4

7. Bonus Episode - Extra Dose Dec 24, 2024

Show notes

Right, roll up your sleeve, it’s time for an extra dose of Best Medicine!

This is a special episode of unheard bits that couldn’t be squeezed into Series 2, featuring more fascinating medical insights, extended bits and a whole Petri dish of jokes – some more cultured than others.

Laura Smyth shares more on sleep, Zoe Lyons delves into transplants and Dr Lindsey Fitzharris takes Kiri through more weird ritualistic historical medical practices. Dr Matt Morgan talks about the time he stripped naked and covered himself in honey in the name of science, Daliso Chaponda is still in denial about denial, Dr Mark Williams blows Kiri's mind with his unexpected swimming career, and Reverend Benjamin Perry opens up again about the benefits of crying.

Best Medicine is your weekly dose of laughter, hope and incredible medicine. Award-winning comedian Kiri Pritchard-McLean is joined by a funny and fascinating panel of comedians, doctors, scientists, and historians to celebrate medicine’s inspiring past, present and future.

Each week, Kiri challenges her panel to make a case for what they think is 'the best medicine', and each guest champions anything from world-changing science or an obscure invention, to an every-day treatment, an uplifting worldview, an unsung hero or a futuristic cure.

Whether it’s futuristic origami surgical robots, life-changing pineapple UTI vaccines, Victorian scandal mags, denial, sleep, tiny beating organoid hearts, lifesaving stem cell transplants, gold poo donors or even crying - it’s always something worth celebrating.

Hosted by Kiri Pritchard-McLean

Featuring: Daliso Chaponda, Fatiha El-Ghorri, Professor Nicholas Embleton, Dr Lindsey Fitzharris, Zoe Lyons, Dr Matt Morgan, Reverend Benjamin Perry, Dr Fotios Sampaziotis, Laura Smyth and Dr Mark Williams

Written by Laura Claxton, Edward Easton, Mel Owen, Kiri Pritchard-McLean, and Ben Rowse

Producers: Tashi Radha and Ben Worsfield

Theme tune composed by Andrew Jones

A Large Time production for BBC Radio 4

6. Pain Management, Organoids, Prosthetic Leg Covers Dec 24, 2024

Show notes

Joining Kiri this week is comedian Desiree Burch who explains the best ways to cope with pain following surgery. Dr Abdullah Khan engineers mini versions of human organs in a dish to enable more effective testing of new medical treatments, and Mark Williams shows off personalised prosthetic legs clad in anything from gold and flames to beer and the Welsh Flag.

Best Medicine is your weekly dose of laughter, hope and incredible medicine. Award-winning comedian Kiri Pritchard-McLean is joined by a funny and fascinating panel of comedians, doctors, scientists, and historians to celebrate medicine’s inspiring past, present and future.

Each week, Kiri challenges a panel of medical experts and a comedian to make a case for what they think is 'the best medicine', and each guest champions anything from world-changing science or an obscure invention, to an every-day treatment, an uplifting worldview, an unsung hero or a futuristic cure.

Whether it’s origami surgical robots, life-changing pineapple UTI vaccines, Victorian scandal mags, denial, sleep, tiny beating organoid hearts, lifesaving stem cell transplants, gold poo donors or even crying - it’s always something worth celebrating.

Hosted by Kiri Pritchard-McLean

Featuring: Desiree Burch, Dr Abdullah Khan and Dr Mark Williams

Written by Laura Claxton, Mel Owen, Kiri Pritchard-McLean, Nicky Roberts and Ben Rowse

Producers: Tashi Radha and Ben Worsfield

Theme tune composed by Andrew Jones

A Large Time production for BBC Radio 4

5. Books, Poetry, Scandal, Writing Dec 17, 2024

Show notes

Joining Kiri this week in a literary special recorded at the Hay Festival is comedian Ignacio Lopez who heals family wounds through writing. Dr Paul Craddock explains how one of the most prestigious medical journals started as a scandal magazine, Miss Shabnam Parkar shares how poetry helps her perform surgery, and Professor Neil Frude walks Kiri through library bookshelves for mental health treatments.

Best Medicine is your weekly dose of laughter, hope and incredible medicine. Award-winning comedian Kiri Pritchard-McLean is joined by a funny and fascinating panel of comedians, doctors, scientists, and historians to celebrate medicine’s inspiring past, present and future.

Each week Kiri challenges a panel of medical experts and a comedian to make a case for what they think is 'the best medicine', and each guest champions anything from world-changing science, an obscure invention, an everyday treatment, an uplifting worldview, an unsung hero or a futuristic cure.

Hosted by Kiri Pritchard-McLean

Featuring: Dr Paul Craddock, Professor Neil Frude, Ignacio Lopez, Miss Shabnam Parkar

Written by Edward Easton, Mel Owen, Pravanya Pillay, Kiri Pritchard-McLean, Nicky Roberts and Ben Rowse

Producers: Tashi Radha and Ben Worsfield

Theme tune composed by Andrew Jones

A Large Time production for BBC Radio 4

4. CAR T-cells, Ritual, Water, Crying Dec 10, 2024

Show notes

Joining Kiri this week are Dr Claire Roddie who retrains cells to fight cancer using revolutionary, game-changing CAR T-cell therapy, and comedian Fatiha El-Ghorri who finds spiritual healing in water. Dr Lindsey Fitzharris takes comfort in rituals both historical and present-day to help her remember her grandmother Dorothy Sissors, and Rev Benjamin Perry explains how crying can be the best medicine.

Best Medicine is your weekly dose of laughter, hope and incredible medicine. Award-winning comedian Kiri Pritchard-McLean is joined by a funny and fascinating panel of comedians, doctors, scientists, and historians to celebrate medicine’s inspiring past, present and future.

Each week, Kiri challenges panellists to make a case for what they think is 'the best medicine', and each guest champions anything from world-changing science or an obscure invention, to an everyday treatment, an uplifting worldview, an unsung hero or a futuristic cure.

Hosted by Kiri Pritchard-McLean

Featuring: Fatiha El-Ghorri, Dr Lindsey Fitzharris, Rev Benjamin Perry and Dr Claire Roddie

Written by Laura Claxton, Edward Easton, Mel Owen, Kiri Pritchard-McLean and Ben Rowse

Producers: Tashi Radha and Ben Worsfield

Theme tune composed by Andrew Jones

A Large Time production for BBC Radio 4