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    Science

    BBC Inside Science

    A weekly programme that illuminates the mysteries and challenges the controversies behind the science that’s changing our world.

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    Copyright: © (C) BBC 2026

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    Latest Episodes:
    TB vaccination to replace culling in badgers; Neil Shubin on the wonders of evolution Mar 19, 2020
    Show notes

    The government have announced that the controversial cull of badgers across England will begin to be phased out in the next few years. It will be replaced by vaccinating badgers for bovine TB. The cull is intended to cut tuberculosis in cattle and has killed at least 100,000 badgers since 2013. TB in cattle is a severe problem for farmers and taxpayers, leading to the compulsory slaughter of 30,000 cattle and a cost of £150m every year. However culling is thought to have failed because frequent trading of cattle and poor biosecurity on farms severely hampering efforts to tackle the crisis. Expert and ecologist Rosie Woodroffe at the Institute of Zoology, the research division of the Zoological Society of London, who has been trialling vaccinations for the past few years in Cornwall explains to Marnie Chesterton why it is highly desirable to move from culling to vaccination of badgers. Plus they discuss the parallels between this and the coronavirus outbreak in humans.

    Evolutionary biologist Neil Shubin at the University of Chicago, is also the author of the best-selling book on evolution – ‘Your Inner Fish’. In his new book, out this week, ‘Some Assembly Required – Decoding four billion years of life from ancient fossils to DNA’, Neil revisits the topic of evolutionary development and explains to Adam how we have now arrived at a remarkable moment—prehistoric fossils coupled with new DNA technology have given us the tools to answer some of the basic questions of our existence: How do big changes in evolution happen? Is our presence on Earth the product of mere chance? This new science reveals a multi-billion-year evolutionary history filled with twists and turns, trial and error, accident and invention.

    Presenter - Marnie Chesterton Producer – Fiona Roberts


    Biology of the new coronavirus Mar 12, 2020
    Show notes

    Adam Rutherford explores what makes the new coronavirus so effective at making us ill. Jonathan Ball, Professor of Virology at Nottingham University, explains the structure of the virus and how it gets into our lungs. Evolutionary virologist at Cambridge University, Dr Charlotte Houldcroft talks to Adam about how labs are detecting the virus and how they are studying the way it mutates to understand how it's moving around the world. Kate Jones, Professor of Ecology at UCL, tells Adam how bats live with coronaviruses, but they don't get sick. She says the reason they have moved from bats to humans is because we have taken them out of their natural habitat into places like the wet markets of East Asia. Sarah Gilbert at Oxford University explains how her team is developing vaccines, and Jonathan Ball looks at work to repurpose existing drugs that may be used as treatment for Covid-19.


    Banning lead shot for hunting; UK Fireball Network and Extremely thin gold Mar 05, 2020
    Show notes

    We have known for centuries about the toxic properties of lead, and we have known since at least 1876 that birds die of lead poisoning when they eat lead gunshot (which they do, thinking its grit). To address this, in 1999, the use of lead ammunition in England was restricted. These Regulations prohibit the use of lead ammunition in certain habitat (predominately wetlands) and for the shooting of all ducks and geese, coot and moorhen. However compliance with these Regulations is low. And what about other animals (game birds and game animals) hunted with lead ammunition? It’s only been since 2008 that it’s been demonstrated that that animals shot with lead were a risk to the health of people who ate them. Tiny particles of the toxic metal remain in the meat and are consumed. Children are especially vulnerable to lead toxicity, which causes problems with brain development. Leading Cambridge conservation scientist Professor Debbie Pain, has been studying lead in the environment for her entire career. So it’s good news to her that, 8 of the main UK shooting organisations have voluntarily agreed to ban lead shot for all live quarry by 2025. But is a voluntary ban is enough? And what are the Department of Food and Rural Affairs (DEFRA) doing to monitor and manage the problem?

    It can be a real treat to watch a meteor shower in the night sky and you can consider yourself lucky if you get to witness a fireball streaking through the atmosphere. But what the scientists in the Global Fireball Observatory really want is to find these fist-sized extra-terrestrial meteoroids where they land on Earth. One of the Fireball UK Network’s leaders, Luke Daly at the University of Glasgow, explains how, if we know where in the Solar system these rocks came from and we can analyse their make-up, we can learn a lot about how our Solar System was made. However surprising few of the 5000 tonnes of meteorites that land on our planet every year are retrieved. Most are sand-sized grains and many fall in the sea. But even tracking down these precious rocks on land is extremely difficult. So the Network has a suite of cameras watching the sky, and together with some clever number-crunching algorithms, they can track these events and narrow down where to search. But they still need the good citizens of Britain to help find them. If you want to get involved (and this is a good one for schools to take part in) email UKFM@Imperial.ac.uk or follow @fireballsUK on Twitter.

    We are fast learning that elements at the nanoscale have vastly different properties than they do in the form we can observe them. It’s proving to be a rich field for changing the properties of materials, and inventing new substances that might be of use in medicines, in electronics, and much more. Inside Science’s Maddie Finlay went to meet Stephen Evans from the University of Leeds, where they have been tinkering with a substance that definitely doesn’t glister even though it’s gold.

    Producer: Fiona Roberts


    The Big Compost Experiment; Using AI to screen for new antibiotics; Science of slapstick Feb 27, 2020
    Show notes

    Composters - we need you! Or rather materials scientists at UCL, Mark Miodownik and Danielle Purkiss, need you to take part in their Big Compost Experiment. Launched back in November, the team asked members of the public to fill in an online questionnaire about their composting and recycling habits. With special reference to plastic packaging labelled as 'compostable', they want you to see whether your compost bin at home can break down these products. Despite starting in the coldest season, where compost production really slows down, they've had some success. To take part, go to https://www.bigcompostexperiment.org.uk/

    One particular infectious disease (Covid-19) is dominating the headlines, but it's by no means the only one we should be concerned about. There's an infectious disease crisis that is longstanding, and one of the most significant threats to global health. It’s the on-going antibiotic resistant crisis. Antibiotics kill bacteria, but bacteria evolve resistance very quickly, and because of overuse of antibiotics, we’ve effectively driven the evolution of many disease causing bacteria to be resistant to our best antibiotics, thus rendering them redundant as drugs. On top of that, we haven’t found any new classes of antibiotics for many years. And the cost of developing new drugs is very high – billions, and the financial incentive for developing antibiotics is low. So this is a perfect storm. A new study this week shows a glimmer of light in the quest to find new antibiotics, via artificial intelligence. Lena Ciric, a microbiologist at University College London, explains how the new drug Halicin was found and the promise it holds as a new antibiotic.

    Slapstick is one of the most universally appreciated comedy styles. The physical comedy that made Charlie Chaplin, Laurel & Hardy and even Mr Bean so popular has transfixed and entertained generations. But how has it endured the test of time? Why do we enjoy seeing characters in pain? Or is it something deeper rooted that it tells us about the human condition? Laughter is a social action – we do it to show we understand a joke and to signal to people that we get along with them. 'Told By An Idiot' is a theatre company exploring the divide between comedy and tragedy who are currently performing a slapstick style show about the relationship between Charlie Chaplin and Stan Laurel, who had been his understudy. Hannah Fisher has been to see the show.

    Producer - Fiona Roberts


    Coronavirus questions; HMS Challenger and ocean acidification; Sean Carroll's quantum world Feb 20, 2020
    Show notes

    Adam Rutherford is joined by Professor of Virology at Nottingham University, Jonathan Ball, to help answer some of your questions on the latest coronavirus outbreak. Will it become endemic, and once infected and recovered how long are we resistant to the virus? And can face masks and alcohol hand gels help prevent infection?

    In the 1870's the scientific research ship, HMS Challenger, sailed all the world's oceans measuring sea temperatures, ocean depths and sampling the geology of the seabed. But it's the seawater samples, containing microscopic zooplankton, preserved for 130 years which intrigued climate scientist Dr. Lyndsey Fox. She has been measuring the thickness of the shells of Foraminifera - tiny single-celled organisms - as a way of measuring how much the ocean has acidified over time. The shells are made of calcium carbonate, that is much harder to accrete when the pH drops.

    Theoretical physicist Sean M. Carroll is very good at explaining the unexplainable. He chats to Adam about his latest book - Something Deeply Hidden: Quantum Worlds and the Emergence of Spacetime.

    Producer: Fiona Roberts


    Ordnance Survey - Britain's 220-year-old tech company; Launching synthetic voices and personality test Feb 13, 2020
    Show notes

    For the past 220 years, Ordnance Survey have been mapping Great Britain with extraordinary accuracy. But as Gareth discovers when he visits their HQ in Southampton, GB's master map is not a static printed document. It's a 2 petabyte database which is updated up to 20,000 times a day. This adds up to 360 million updates a year. Since the development of the theodolite and the first detailed map in 1801 of the county of Kent, Ordnance Survey have used cutting edge technology, not only to map our lands, but to manipulate, understand and ask questions of the geography of our natural landscapes and built environment.

    Voices on the train, public address announcements at the station, automated telephone banking, Alexa and Siri. We are surrounded by electronic voices. But very little research has been done of how we respond to synthetic speech. To investigate the impact of artificially generated voices in our lives, BBC R&D together with our favourite acoustic engineer, Professor Trevor Cox of the University of Salford, has just launched a study. The Synthetic Voices and Personality Test, is an online test we want you to take part in. Please go to https://voicestudy.api.bbc.co.uk and have a listen

    Presenter Gareth Mitchell Producer - Fiona Roberts


    Solar Orbiter launch; Mutational signatures in cancer; paleo-oncology Feb 06, 2020
    Show notes

    The latest space mission to the Sun is due to launch on Sunday. SolO, the European Space Agency's Solar Orbiter, will loop around our star in an elliptical orbit, sling-shotting around Venus. Professor Richard Harrison at the Rutherford Appleton Laboratory has been on the mission from its conception, he details the instruments and what they're hoping to discover about the Sun and its impact on space weather back here on Earth.

    If chemicals in cigarette smoke or exposure to UV light played a role in causing a cancerous tumour, we can now see this evidence in the DNA. These and other causes of cancer are being catalogued by a huge international study revealing the genetic fingerprints of DNA-damaging processes that drive cancer development. Professor Mike Stratton, is director of the Wellcome Sanger Institute and author of one of many papers released in Nature and associated journals this week that detail the results of the Pan-Cancer of Whole Genomes Consortium.

    Cancer is not a modern disease. Evidence in bones and remains reveal our ancient ancestors also suffered. Dr. Kate Hunt is a paleo-pathologist studying paleo-oncology, a very specific, very recent branch of archaeology, looking through ancient burial sites, artefacts and literature for signs of cancer.

    Presenter - Marnie Chesterton Producer - Fiona Roberts


    Coronavirus update, Typhoid Mary and 200th anniversary of the first sighting of Antarctica Jan 30, 2020
    Show notes

    With the recent coronavirus outbreak spreading around the world, and concerns about people being infectious before they exhibit any symptoms. Professor of Virology at Nottingham University Jonathan Ball explains infection rates, quarantines and why he's worried about it spreading to the developing world.

    'Alice in Typhoidland' is a new exhibition in Oxford recording how that city dealt with typhoid. It’s called that after one of its 19th century residents, Alice Liddell (the girl after whom Alice in Wonderland was named). Her father Henry Liddell was the Dean of Christchurch College and together with his friend Henry Ackland was instrumental in closing off Oxford's open sewers and thereby combating some of the causes of the disease. The exhibition also explores the fate of Typhoid Mary – one of the most famous asymptomatic disease carriers in history.

    Exactly 200 years ago, 30th January 1820, at 3:30 local time, the continent of Antarctica was spotted for the first time by a British expedition captained by Edward Bransfield, on the Merchant Ship The Williams. But they weren’t the very first: 3 days earlier - on 27 January - a Russian expedition led by Fabian Gottlieb von Bellingshausen and Mikhail Lazarev spotted what is now known as the Fimbul Ice Shelf. The UK Antarctic Heritage Trust is spearheading celebrations. Camilla Nichol is its CEO and she describes the history of the icy continent and how it's become the protected scientific reserve it is now.

    Producer - Fiona Roberts


    Coronavirus outbreak in China; Genetic diseases in Amish communities and getting an Egyptian mummy to speak Jan 23, 2020
    Show notes

    With news reports moving as quickly as the virus may be spreading, the latest coronavirus outbreak which is thought to have started in Wuhan in central China is fast becoming a global health concern. Adam Rutherford speaks to BBC Inside Science's resident virologist Professor Jonathan Ball from Nottingham University, who says one of the most urgent things to do is to find out where the virus came from, and what animal it jumped to humans from.

    The Anabaptist Amish communities are some of the fastest growing populations on the planet. They came to the US from the Swiss-German border in the 18th and 19th centuries and have maintained their plain, simple community-minded way of life. Partly because they all descended from the same geographical area and partly because they tend to marry within their own communities, they can suffer from a particular spectrum of genetic disorders. Professor Andrew Crosby and Dr. Emma Baple from Exeter University have been studying these diseases, including a number new to medicine, and in return they are helping the Amish to understand and treat some of these debilitating diseases.

    He may currently sound more like a sheep baa-ing, but in a proof of concept experiment, Professor David Howard, an electrical engineer at Royal Holloway University of London, has been able to scan, 3D print and electronically reanimate the vocal tract of Nesyamum, a 3000 year old Egyptian mummy. The eventual hope is to recreate his tongue and try to get him to sing.

    Producer - Fiona Roberts


    Reproducibility crisis in science; Aeolus wind-measuring satellite; electric cars Jan 16, 2020
    Show notes

    Science is built upon the idea that results can be verified by others. Scientists do their experiments and write up their methods and results and submit them to a journal that sends them to other scientists, who check them and if they pass muster, the study gets published for further scrutiny. One of the keystones of this process is that results can be reproduced. If your results can’t be replicated, something is amiss. Over the last few years, particularly in the field of psychology, many high profile findings have not been reproduced. Now, the same problems that have plagued psychology are spilling over into other areas. This week, a study showed that ocean acidification does not significantly alter fish behaviour, as had been reported several times before. Adam Rutherford discusses the crisis with Matthew Cobb, Professor of Zoology at Manchester University.

    ESA’s Aeolus mission was launched in August 2018. It’s one of the European Space Agency’s Earth Explorer satellites. The Aeolus satellite uses lasers to monitor the wind by firing an ultraviolet laser beam into the atmosphere and catching the light’s reflection as it scatters off molecules and particles carried along in the air. It was planned to be very much a proof of principle mission, testing the science, with longer-term plans for a whole constellation of wind monitoring satellites. But Aeolus has performed so well in the tests that, unusually for meteorological science, the results are now considered robust enough to be inputted into the European Centre for Medium-Range Weather Forecasts models.

    The UK is aiming to phase out conventional combustion engines in favour of more energy-efficient, less polluting electric vehicles by 2040. In response to a listener’s question on the cleanliness of these machines, BBC Inside Science reporter, Tristan Varela, conducts an investigation in the streets, garages, and laboratories of London. He finds that electric cars are relatively clean in the UK, where energy generation from renewable sources has recently overtaken fossil fuels. However, sales of new electric cars are still heavily outweighed by large, fossil fuel hungry, SUVs. But some people are instead converting existing cars to make their vehicles more environmentally-friendly.

    Producer - Fiona Roberts


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