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    Health & Fitness

    ZOE Science & Nutrition

    The world’s top scientists explain the latest health, nutrition, and gut health research and translate it into practical advice to improve your health & weight. Join ZOE Science & Nutrition, on a journey of scientific discovery. Hosted by Jonathan Wolf.

    Advertise

    Copyright: © Copyright 2024 ZOE

    • Apple Podcasts
    • Google Play
    • Spotify

    Latest Episodes:
    Most replayed moment: The five fundamental pillars of longevity | Kayla Barnes-Lentz & Dr Federica Amati Nov 10, 2026
    Show notes

    Kayla Barnes-Lentz follows an intensive, highly structured daily protocol designed by a team of scientists to optimise every aspect of her health. She believes this carefully curated lifestyle could help her live to 150 years or more.

    While her routine may not be realistic for everyone, the insights behind it could benefit us all.

    Today, Kayla joins Dr Federica Amati to break longevity down into five fundamental pillars.

    Together, they explore the science behind each one, how Kayla puts them into practice, and how you can start strengthening your own pillars today.


    🌱 Try our science-backed and tasty wholefood supplement Daily30

    🌿Let your gut microbes snack on the ZOE Gut Health Bar

    Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

    Follow ZOE on Instagram.


    📚Books by our ZOE Scientists

    The Food For Life Cookbook

    Every Body Should Know This by Dr Federica Amati

    The Appetite Reset by Dr Federica Amati

    Food For Life by Prof. Tim Spector

    Ferment by Prof. Tim Spector

    Good Mood Food (preorder) by Prof. Tim Spector

    Free resources from ZOE

    The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt

    The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra

    Eating for Better Brain Health: Your brain-gut blueprint

    How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

    Live Healthier: Top 10 Tips From ZOE Science & Nutrition

    Gut Guide - For a Healthier Microbiome in Weeks

    Better Breakfast Guide


    Have feedback or a topic you'd like us to cover? Let us know here.

    Episode transcripts are available here.



    How to NOT get sick this winter - 3 foods to fight colds, beat flu season and protect your immune system | Prof Daniel Davis & Prof Tim Spector Nov 05, 2026
    Show notes

    Why do you catch every cold going, while others rarely get sick?


    Many of the cold and flu tips you grew up with are myths, but in today’s episode, world-leading immunity expert Professor Daniel Davis and Professor Tim Spector explain the five everyday habits that can protect your immune system.


    You’ll learn why some people get sick more often than others and test common beliefs about how to boost immunity and beat flu season: does getting cold and wet really give you a cold, and can vitamin C or immune-boosting supplements actually help? We explore the five habits that the science links to immune health and share three food tips, so you can learn how to stay well this winter.


    If you get sick more often than your friends, this episode will break down why that might be, and give you the tools to help.


    🌱 Try our science-backed and tasty wholefood supplement Daily30

    🌿Let your gut microbes snack on the ZOE Gut Health Bar

    Build healthy habits. Download the ZOE app today 👉 Join ZOE

    Follow ZOE on Instagram.


    Timecodes

    00:00 Intro

    05:57 Can you really boost your immune system?

    07:51 Is man flu real? The science of who suffers worse colds.

    11:55 Why you take a week to shake off a cold your friend beats in 2 days.

    14:20 Is catching colds in your genes?

    15:54 Why your immune system slows with age, and the inflammation link.

    20:16 Why do we actually get more colds and flu in winter?

    21:28 Why your snot is magical, and how it fights colds.

    22:31 Can wet hair give you a cold?

    24:06 Vitamin C, vitamin D or zinc: do any supplements stop a cold?

    27:36 The truth about immune-boosting supplements and food labels

    29:38 Should you feed a cold and starve a fever?

    31:30 Should you avoid crowds to prevent colds?

    34:09 Habit 1: What 4 hours’ sleep does to your immune system.

    36:48 How to sleep better: Tim Spector's routine

    38:56 Habit 2: what the stress hormone cortisol does to your cancer-fighting cells

    42:24 How to lower cortisol: do tai chi, walks or laughter work?

    45:22 Habit 3: is a glass of wine bad for your immune system?

    46:13 Habit 4: why gut health is Tim Spector’s main reason for not getting sick.

    48:04 How gut bacteria keep your immune system in balance

    49:39 Does diet change how sick you get?

    51:57 Habit 5: how exercise changes your immune system, and the truth about 10,000 steps.

    54:28 Is it too late to start exercising for immune health?

    55:42 Tim Spector’s 3 food rules for your immune system and gut health

    57:47 The 5 habits that really protect your immune system.


    📚Books by our ZOE Scientists

    The Food For Life Cookbook

    Every Body Should Know This by Dr Federica Amati

    The Appetite Reset by Dr Federica Amati

    Food For Life by Prof. Tim Spector

    Ferment by Prof. Tim Spector

    Good Mood Food by Prof. Tim Spector


    Free resources from ZOE

    The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt

    The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra

    Eating for Better Brain Health: Your brain-gut blueprint

    How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

    Live Healthier: Top 10 Tips From ZOE Science & Nutrition

    Gut Guide - For a Healthier Microbiome in Weeks

    Better Breakfast Guide


    Mentioned in today's episode

    ⁠Immune Health: A Myth-busting Guide by Prof Daniel Davis

    The science behind “man flu”, BMJ (2017)

    Sleep and food choices, ZOE (2025)

    Childhood adversity and inflammatory processes, Psychoneuroendocrinology (2013)

    Effect of Sleep Deprivation on Response to Immunization, JAMA (2002)

    Increased concordance of severe respiratory infection in identical twins, Pediatrics (2008)

    Longitudinal dynamics of gene expression and metabolomics in an aging population cohort, Science (2026)

    The nonlinear association between sleep duration, cognition and mental health, Nat Aging 2 (2022)

    Effects of odors on sleep quality, Scientific Reports (2022)
    Diet quality and risk and severity of COVID-19, Gut (2021)


    Episode transcripts are available ⁠here⁠.


    Most replayed moment: How to prevent microplastics entering your body | Dr Sabine Donnai & Dr Federica Amati Nov 03, 2026
    Show notes

    Microplastics are everywhere. Tiny fragments we can’t see, taste, or smell and yet they’ve been found in our water, our food, and even our brains.

    Emerging research has linked microplastic exposure to hormone disruption, chronic inflammation, and a higher risk of cardiovascular disease. But with plastics embedded in almost every aspect of modern life, is there anything we can realistically do to reduce our exposure?

    Today, Dr Sabine Donnai and Dr Federica Amati separate the fear from the facts. They explain where our biggest sources of microplastics come from, which everyday habits may be increasing our risk, and the simple, practical swaps that can meaningfully reduce the amount entering our bodies.


    🌱 Try our science-backed and tasty wholefood supplement Daily30

    🌿Let your gut microbes snack on the ZOE Gut Health Bar

    Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

    Follow ZOE on Instagram.


    📚Books by our ZOE Scientists

    The Food For Life Cookbook

    Every Body Should Know This by Dr Federica Amati

    The Appetite Reset by Dr Federica Amati

    Food For Life by Prof. Tim Spector

    Ferment by Prof. Tim Spector

    Good Mood Food (preorder) by Prof. Tim Spector


    Free resources from ZOE

    The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt

    The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra

    Eating for Better Brain Health: Your brain-gut blueprint

    How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

    Live Healthier: Top 10 Tips From ZOE Science & Nutrition

    Gut Guide - For a Healthier Microbiome in Weeks

    Better Breakfast Guide


    Have feedback or a topic you'd like us to cover? Let us know here.

    Episode transcripts are available here.



    Inside the daily routine of the world’s best nutrition doctor - the 6 things you need every day to cut your risk of cancer & dementia | Dr Federica Amati Oct 29, 2026
    Show notes

    What does a healthy daily routine really look like?

    In this episode, world-leading nutritionist Dr Federica Amati shares what she eats in a day, from breakfast to dinner, and her six everyday habits that may lower your risk of cancer, dementia and help you live longer. No 4am alarms, cryotherapy chambers, or other protocols - you’ll learn simple tips and trends you can skip.

    Federica walks us through a normal day, from waking up to bedtime, and gives you six pillars of a healthy lifestyle to focus on to reduce your risk of chronic disease.

    Learn how Federica builds a healthy morning routine that cuts your chronic disease risk by 80%, how to put together a quick lunch, pick snacks that keep you full, and slip oily fish into meals you already love. Plus, her simple wind-down rules for better sleep.

    Which big habits are you missing while you chase the small ones?

    🌱 Try our science-backed and tasty wholefood supplement Daily30

    🌿Let your gut microbes snack on the ZOE Gut Health Bar

    Build healthy habits. Download the ZOE app today 👉 Join ZOE

    Follow ZOE on Instagram.


    Timecodes

    00:00 Intro

    04:45 Circadian rhythms: what your hormones expect every 24 hours

    06:50 The 6 lifestyle habits that prevent 80% of chronic disease

    10:10 Why sleep scientists want to scrap the clock change

    13:14 Coffee on an empty stomach: science vs. social media myths

    14:46 Is eating the exact same breakfast every day bad for you?

    16:57 The high-protein, high-fibre breakfast you can make in seconds

    19:05 The no-cook lunch for busy workdays

    20:35 Are pre-cooked grain pouches healthy?

    23:10 Does microwaving fermented foods destroy their benefits?

    25:26 The science of beans: how fibre shuts down hunger for hours

    28:23 Why sandwiches cause an afternoon energy crash

    32:17 Is pasta actually bad for you?

    36:04 The real reason you feel starving at 3 pm

    38:14 Nutritionist-approved snacks: sweet & savoury ideas that work

    40:22 The clinical evidence on red meat & cancer risk

    41:15 SMASH: the 5 oily fish to eat for omega-3

    44:38 Tinned tuna: mercury risk & missing healthy fats

    46:52 Which cooking oil should you use?

    49:19 Do gut microbes control your food cravings?

    50:45 The overnight fast: should you eat dinner earlier?

    52:50 The 1 screen habit that beats any sleep routine

    54:29 The healthy habit wellness influencers get wrong about longevity

    58:16 The single most overlooked life skill that makes healthy food cheaper


    📚Books by our ZOE Scientists

    The Food For Life Cookbook

    Every Body Should Know This by Dr Federica Amati

    The Appetite Reset by Dr Federica Amati

    Food For Life by Prof. Tim Spector

    Ferment by Prof. Tim Spector

    Good Mood Food (preorder) by Prof. Tim Spector


    Free resources from ZOE

    The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt

    The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra

    Eating for Better Brain Health: Your brain-gut blueprint

    How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

    Live Healthier: Top 10 Tips From ZOE Science & Nutrition

    Gut Guide - For a Healthier Microbiome in Weeks

    Better Breakfast Guide


    Mentioned in today's episode

    Daylight-saving Time & Health Identifying Beneficial & Adverse Effects, Eur J Epidemiol (2026)

    The Interplay between Early Mealtime, Circadian Rhythms, Gene Expression, Circadian Hormones, and Metabolism⁠, Clocks & sleep (2023)


    Episode transcripts are available here.


    Most replayed moment: Why appreciating flavour could stop you overeating | Spencer Hyman & Professor Tim Spector Oct 27, 2026
    Show notes

    Why is it so hard to stop eating certain foods? Most of us assume it comes down to willpower. But according to today’s guests, the answer may actually lie in the difference between taste and flavour. Because while those two words sound interchangeable, they describe very different experiences.

    Taste is often engineered - carefully designed by big food companies to keep us craving more. Flavour, on the other hand, is something deeper. It’s the rich, complex experience that comes from high-quality produce.

    Today, Spencer Hyman and Professor Tim Spector explain how ultra-processed foods manipulate our brains and why rediscovering flavour could help us eat less without feeling deprived. They’ll reveal practical ways that you can retrain your palate and reconnect with real food.


    🌱 Try our science-backed and tasty wholefood supplement Daily30

    🌿Let your gut microbes snack on the ZOE Gut Health Bar

    Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

    Follow ZOE on Instagram.



    📚Books by our ZOE Scientists

    The Food For Life Cookbook

    Every Body Should Know This by Dr Federica Amati

    The Appetite Reset by Dr Federica Amati

    Food For Life by Prof. Tim Spector

    Ferment by Prof. Tim Spector

    Good Mood Food (preorder) by Prof. Tim Spector


    Free resources from ZOE

    The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt

    The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra

    Eating for Better Brain Health: Your brain-gut blueprint

    How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

    Live Healthier: Top 10 Tips From ZOE Science & Nutrition

    Gut Guide - For a Healthier Microbiome in Weeks

    Better Breakfast Guide


    Have feedback or a topic you'd like us to cover? Let us know here.

    Episode transcripts are available here.



    How to use food as medicine to reverse disease in months - the top 5 foods you must eat to live longer | Dr Dariush Mozaffarian Oct 22, 2026
    Show notes

    Can using food as medicine protect your heart health, prevent chronic disease, and help you live longer?

    In this episode, leading cardiologist and Director of the Food is Medicine Institute, Dr Dariush Mozaffarian, explains how modern diets increase your risk of heart attacks and why standard medical advice often falls short.

    Dariush looks at how past dietary guidelines shaped today’s food system and why shifting focus to whole, protective foods improves your health. He also explains why counting calories fails, shows how ultra-processed foods took over our food supply, and asks whether saturated fat deserves its reputation as a cause of heart disease.

    Through the idea that food is medicine, you’ll learn how to adopt healthy eating habits by identifying protective foods - forming practical diet shifts that can control your blood sugar, lower cholesterol, support your gut health, and cut your risk of heart attacks and strokes.

    What if the most effective prescription for a longer, healthier life is already on your plate?

    🌱 Try our science-backed and tasty wholefood supplement Daily30

    🌿Let your gut microbes snack on the ZOE Gut Health Bar

    Build healthy habits. Download the ZOE app today 👉 Join ZOE

    Follow ZOE on Instagram.


    Timecodes

    00:00 Intro

    04:22 Is a poor diet deadlier than smoking?

    09:13 Why the foods you're missing may harm you more than junk food

    10:33 Could diet prevent half of all heart attacks and strokes?

    11:29: Can diet reverse gut problems in months?

    14:25 Why diet-related disease exploded in just 35 years

    15:40 Nutrition science is younger than you think

    17:51 Why poor nutrition became a national security threat in 1941

    19:27 Why do we refine grains, then put the vitamins back in?

    21:03 How bomb factories changed the food on your plate

    24:46 Why did we go low-fat? The 1980 dietary guidelines mistake

    26:45 Did tobacco companies really own food brands?

    31:09 The 3 things driving the rise of chronic disease

    33:52 Is fat really the problem?

    36:38 Exercising more but still gaining weight? Here's why

    37:33 Has our resting energy expenditure gone down?

    39:28 Is modern food starving your gut microbes?

    41:02 Are dietary guidelines any good? A cardiologist’s verdict

    43:02 What do dietary guidelines say to avoid?

    45:37 Do we really need more protein?

    47:21 Healthy eating made simple: 3 food groups to know

    48:17 How many calories does your gut microbiome digest?

    52:29 Is red meat bad for you?

    54:11 Is saturated fat bad for your heart?

    56:21 How to lower cholesterol with food: a cardiologist's 2 tips

    57:13 Should your doctor prescribe food?

    1:00:37 Can we fix the food system in 10 years?


    📚Books by our ZOE Scientists

    The Food For Life Cookbook

    Every Body Should Know This by Dr Federica Amati

    The Appetite Reset by Dr Federica Amati

    Food For Life by Prof. Tim Spector

    Ferment by Prof. Tim Spector

    Good Mood Food (preorder) by Prof. Tim Spector


    Free resources from ZOE

    The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt

    The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra

    Eating for Better Brain Health: Your brain-gut blueprint

    How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

    Live Healthier: Top 10 Tips From ZOE Science & Nutrition

    Gut Guide - For a Healthier Microbiome in Weeks

    Better Breakfast Guide


    Mentioned in today's episode
    Food Additives: Emerging Detrimental Roles on Gut Health, FASEB journal (2025)

    Diet Is the Single Most Important Predictor of Health, Alternative and Complementary Therapies (2019)

    Total daily energy expenditure has declined over the past three decades, Nat Metab (2023)


    Most replayed moment: Why fermented foods are the future of gut health | Professor Tim Spector Oct 20, 2026
    Show notes

    Fermented foods have evolved from a niche health trend into a supermarket staple. Kefir, kimchi, kombucha. Our shelves are now filled with products rich in beneficial bacteria.

    But with so many options to choose from, it can be difficult to know where to begin.

    Today, Professor Tim Spector shares simple, practical ways to incorporate fermented foods into your daily meals. He’ll also show why fermenting at home is much easier than most people think, taking us inside his fridge to demonstrate how to make four of his favourite homemade ferments.


    🌱 Try our science-backed and tasty wholefood supplement Daily30

    🌿Let your gut microbes snack on the ZOE Gut Health Bar

    Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

    Follow ZOE on Instagram.


    📚Books by our ZOE Scientists

    The Food For Life Cookbook

    Every Body Should Know This by Dr Federica Amati

    The Appetite Reset by Dr Federica Amati

    Food For Life by Prof. Tim Spector

    Ferment by Prof. Tim Spector

    Good Mood Food (preorder) by Prof. Tim Spector

    Free resources from ZOE

    The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt

    The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra

    Eating for Better Brain Health: Your brain-gut blueprint

    How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

    Live Healthier: Top 10 Tips From ZOE Science & Nutrition

    Gut Guide - For a Healthier Microbiome in Weeks

    Better Breakfast Guide


    Have feedback or a topic you'd like us to cover? Let us know here.

    Episode transcripts are available here.



    The 9 best foods to beat the winter blues, end brain fog and stop anxiety | Prof Tim Spector Oct 15, 2026
    Show notes

    Can what you eat protect your memory, ease brain fog, and lift your mood?

    For a long time, we thought the brain was separate from the rest of the body. It's easy to assume that mood, energy, and memory have little to do with what's on your plate.

    But in today's episode, one of the world’s leading experts in nutrition, Professor Tim Spector, explains how your gut health shapes your brain health. From low energy and anxiety today to dementia in later years, he shares what to eat to protect your brain throughout your life. Tim shares nine foods to add to your diet - from mushrooms and eggs to tofu and fermented foods - with easy ways to eat more of them, all drawn from his new book, Good Mood Food.

    By the end of the episode, you will have learned quick, budget-friendly recipes that support the gut-brain connection and will clearly understand the four principles you need to start boosting brain function today.

    What if your tiredness, brain fog, and low mood are linked to the food on your plate? What might change if you ate differently for two weeks?

    🌱 Try our science-backed and tasty wholefood supplement Daily30

    🌿Let your gut microbes snack on the ZOE Gut Health Bar

    Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE

    Follow ZOE on Instagram.


    Timecodes

    00:00 Intro

    04:24 Why better gut health shows up in your brain first

    06:05 Gut-brain connection explained: the vagus nerve is 80% gut to brain

    10:30 Is the “chemical imbalance” theory of mental illness wrong?

    12:28 What a week of fried chicken does to your brain

    15:20 How a gut-friendly diet sends calming signals to your brain

    17:17 How inflammation and blood sugar spikes damage brain cells

    19:33 Does type 2 diabetes really triple dementia risk?

    23:03 SMILES trial: can a gut-friendly diet ease depression?

    26:06 How many plants should you eat per week? 30 or 40?

    28:22 Why ultra-processed food is bad for your brain:t’s not just additives

    29:56 Can intermittent fasting lift your mood?

    32:44 Always tired? Why it might be a brain signal

    36:19 Healthy comfort food: mac and cheese, fish and chips

    39:16 Are mushrooms linked to 25% lower dementia risk?

    42:18 Are eggs good for brain health? How many a week is OK?

    44:03 Best omega-3 foods for brain health: the SMASH fish rule

    46:27 Is tofu good for your brain? How to cook it in 30 seconds

    49:52 Do herbs and spices help your brain? What we know so far

    52:10 Is your brain really made of fat? Why nuts and seeds matter

    54:29 Do you need to soak beans and lentils for hours?

    56:41 Don’t pour away chickpea water: egg white swap

    58:52 Does heating fermented foods kill the benefits? Postbiotics explained

    1:00:17 Where to start for better mood and brain health: try this for 2 weeks


    📚Books by our ZOE Scientists

    The Food For Life Cookbook

    Every Body Should Know This by Dr Federica Amati

    The Appetite Reset by Dr Federica Amati

    Food For Life by Prof. Tim Spector

    Ferment by Prof. Tim Spector

    Good Mood Food (preorder) by Prof. Tim Spector


    Free resources from ZOE

    The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt

    The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra

    Eating for Better Brain Health: Your brain-gut blueprint

    How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

    Live Healthier: Top 10 Tips From ZOE Science & Nutrition

    Gut Guide - For a Healthier Microbiome in Weeks

    Better Breakfast Guide


    Mentioned in today's episode

    Good Mood Food (preorder) by Prof. Tim Spector

    The ZOE METHOD study, ZOE (2024)

    Daily30: Does it work?, ZOE (2026)

    ZOE’s Fermented Food study, ZOE (2025)

    The ‘SMILES’ trial, BMC Med (2017)

    Type 2 Diabetes and Dementia, J Int Neuropsychol Soc (2004)

    The Big IF Study, ZOE (2023)

    Mushroom Consumption and Dementia, J Am Geriatr Soc (2017)

    Egg Consumption and Brain Function, Nutrients (2024)

    Tofu Consumption and Reduced Cancer Risk, Nutrients (2024)

    Unlocking Saffron’s Potential in Brain Health⁠, Cureus (2025)


    Episode transcripts are available here.


    Most replayed moment: Sleep myths that are ruining your rest | Dr Sophie Bostock Oct 13, 2026
    Show notes

    Sleep. It’s a bizarre process when you think about it. We lie down, close our eyes, and before we know it, we’re waking up the next morning with a head full of hazy dreams.

    Because of its mysterious nature, sleep has long been surrounded by all kinds of strange ideas and theories about what might help or harm it. From cheese causing nightmares to turkey making you sleepy.

    So today I’m joined by sleep expert Dr Sophie Bostock to separate fact from fiction. She’ll debunk common sleep myths and share simple, practical tips you can use tonight to improve your sleep.


    🌱 Try our science-backed and tasty wholefood supplement Daily30

    🌿Let your gut microbes snack on the ZOE Gut Health Bar

    Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

    Follow ZOE on Instagram.


    📚Books by our ZOE Scientists

    The Food For Life Cookbook

    Every Body Should Know This by Dr Federica Amati

    The Appetite Reset by Dr Federica Amati

    Food For Life by Prof. Tim Spector

    Ferment by Prof. Tim Spector

    Good Mood Food (preorder) by Prof. Tim Spector

    Free resources from ZOE

    The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt

    The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra

    Eating for Better Brain Health: Your brain-gut blueprint

    How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

    Live Healthier: Top 10 Tips From ZOE Science & Nutrition

    Gut Guide - For a Healthier Microbiome in Weeks

    Better Breakfast Guide


    Have feedback or a topic you'd like us to cover? Let us know here.

    Episode transcripts are available here.



    How to build muscle & stay strong at any age: The surprising links between your gut health, strength training and healthy ageing | Prof Claire Steves & Prof Tim Spector Oct 08, 2026
    Show notes

    How do you build muscle and stay strong as you age?

    For most of us, muscle loss starts in our 30s. It’s easy to think that you can combat this and stay strong into old age by strength training and eating plenty of protein.

    Exercise and macros matter, but scientists are uncovering another important piece of the puzzle - a direct connection between your gut health and healthy ageing. It could change how we think about staying strong as we get older.

    In today's episode, Professor Claire Steves - a world-leading expert in ageing and health - and Professor Tim Spector explore the gut-muscle axis - how your gut microbiome influences your muscle health. They explain why maximum protein doesn't mean maximum muscle, how gut bacteria ‘talk’ to muscle tissue, and why an unhealthy gut can make muscles resistant to growth.

    For listeners looking for simple ways to support their muscles today, this episode includes practical advice you can easily fit into your routine. Claire and Tim share quick daily habits and explain how to get your protein from diverse plant sources.

    Could changing what you feed your gut microbes today be the key to keeping your body strong for decades to come?

    🌱 Try our science-backed and tasty wholefood supplement Daily30

    🌿Let your gut microbes snack on the ZOE Gut Health Bar

    Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE

    Follow ZOE on Instagram.


    Timecodes

    00:00 Intro

    04:08 Why muscle matters for healthy aging, not just the gym

    06:37 The hidden organ: how your muscles talk to your body

    10:35 Why it gets harder to keep muscle as you age

    11:37 Can you have a 20-year-old's muscles at 70?

    13:29 Can muscle loss increase your risk of cancer?

    15:51 Why skinny doesn't mean healthy

    17:40 What is sarcopenia?

    20:52 How 4 days of bed rest can shrink your muscles

    23:31 Gut-muscle axis: how gut bacteria talk to your muscles

    23:53 Why protein stops working as you age

    26:11 Can improving your gut health build stronger muscles?

    28:57 Can strength training change your gut microbiome?

    30:57 Can the Mediterranean diet make your legs stronger?

    34:01 The diet trial that improved muscle and bones, no gym

    34:55 Is there a magic gut bug for building muscle?

    39:38 Intermittent fasting: should you exercise before breakfast?

    44:43 Can too much protein weaken your muscles?

    46:32 How much protein do you really need per day?

    49:20 The best protein foods to feed your gut and muscles

    52:26 Carnivore diet: what meat and shakes do to your gut

    53:46 Strength training, cardio or balance: what do you need?

    56:04 The easy 2-minute toothbrush habit for better muscle health

    57:21 Key takeaways: muscles, microbes, and the protein myth26:11 Can improving your gut health build stronger muscles?


    📚Books by our ZOE Scientists

    The Food For Life Cookbook

    Every Body Should Know This by Dr Federica Amati

    The Appetite Reset by Dr Federica Amati

    Food For Life by Prof. Tim Spector

    Ferment by Prof. Tim Spector

    Good Mood Food (preorder) by Prof. Tim Spector


    Free resources from ZOE

    The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt

    The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra

    Eating for Better Brain Health: Your brain-gut blueprint

    How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

    Live Healthier: Top 10 Tips From ZOE Science & Nutrition

    Gut Guide - For a Healthier Microbiome in Weeks

    Better Breakfast Guide


    Mentioned in today's episode

    Master Cyclist Study, King’s College London (2018)

    Physical Activity and Reduced Cancer Risk, Nat Rev Cancer (2008)

    Bed Rest and Muscle Loss, Diabetes (2016)

    Microbiome Interventions and Inflammation, Cureus (2025)

    The Gut Microbiome and Muscle Strength, BMC Geriatr (2021)

    Resistance Training Reshapes the Gut Microbiome, Sports Med Open (2026)

    The Mediterranean Diet and Muscle Strength, Physiotherapy Theory and Practice (2025)

    Short-Chain Fatty Acids and Muscle Mass, J Cachexia Sarcopenia Muscle (2024)

    Mitochondrial Properties in Skeletal Muscle Fiber⁠, Cells (2023)


    Episode transcripts are available here.


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