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Inventing a Vaccine for Bees Sep 05, 2024

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Dalial Freitak and Annette Kleiser are the co-founders of Dalan Animal Health, a company that has brought to market the first vaccine for insects. Their problem is this: How do you turn a discovery about insect immune systems into a vaccine that can protect the bees we need to grow everything from almonds to blueberries?

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A Better Way to Make the Chemicals in Everything Aug 29, 2024

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Sean Hunt is the co-founder and CTO of Solugen, a company that sells around $100 million a year of industrial chemicals. Sean's problem is this: How do you make the chemicals that go into everything around us -- our food, our clothes, our cars -- without using fossil fuels?

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How Refrigeration Changed the World Aug 08, 2024

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Refrigeration is an underrated technology. It completely transformed what billions of people eat every day.

Today’s guest, Nicola Twilley, tells the story of refrigeration in her new book, Frostbite: How Refrigeration Changed Our Food, Our Planet, and Ourselves. Topics under discussion include: Why brewers were key drivers of refrigeration technology; the extraordinary technology inside a bag of lettuce; and why the technological frontier in food preservation may mean that we don't need to keep so much stuff so cold.

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Detecting Deepfakes With AI Aug 01, 2024

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As generative AI tools improve, it is becoming easier to digitally manipulate content and harder to tell when it has been tampered with. Today we are talking to someone on the front lines of this battle. Ali Shahriyari is the co-founder and CTO of Reality Defender. Ali's problem is this: How do you build a set of models to distinguish between reality and AI-generated deepfakes?

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Turning Old Cans Into Clean Energy Jul 25, 2024

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Aluminum is the most abundant metal in the Earth’s crust. It’s cheap, ubiquitous, and surprisingly energy dense. Peter Godart is the co-founder and CEO of Found Energy. Peter's problem is this: How can you use aluminum as a source of clean, renewable energy?

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Moneyball, Soccer, and the Gap Between Analytics and the Real World Jul 18, 2024

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Sarah Rudd is the co-founder and CEO of the soccer analytics company src | ftbl (It’s pronounced “Source Football.”) Sarah’s problem is this: How do you model a sport as fluid and complex as soccer and translate the analytical insights from the model into meaningful changes on the pitch?

This is the third and final episode of our series about people who are working at the frontiers of technology to help elite athletes perform better.

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Using Computer Vision to See What Coaches Can’t Jul 11, 2024

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Jimmy Buffi is the CEO and co-founder of Reboot Motion, which uses biomechanics to help athletes in Major League Baseball and the NBA. Jimmy's problem is this: How do you turn data about how professional athletes move into knowledge that helps them perform better?

This is the second episode of our series about people who are working at the frontiers of technology to help elite athletes perform better.

Music: Let's Have Some Fruit (The Fruit Song) by J Buffi

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Scanning Every Muscle to Help Olympians Get Stronger Jul 04, 2024

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On the next few episodes of What's Your Problem, Jacob Goldstein is talking with people working at the frontiers of technology to help elite athletes perform better.

Today’s guest is Silvia Blemker, a professor of biomedical engineering at the University of Virginia and the co-founder of Springbok Analytics.
Silvia's problem is this: How do you combine MRI scans and artificial intelligence to generate new insights that can help both elite athletes and people suffering from diseases that affect the muscles.
Springbok's sports clients include medical researchers, Olympic athletes, Major League Baseball and several professional basketball and soccer teams.
This summer, a bunch of Pushkin podcasts are coming out with Olympics-inspired shows. Revisionist History has a series about America's decision to participate in Hitler's Berlin Olympics in 1936. The Happiness Lab has an interview with a coach who coaches coaches. And Cautionary Tales tells the story of the family feud that gave us both Puma and Adidas.

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Making Blood Vessels in a Factory Jun 27, 2024

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Laura Niklason is the co-founder and CEO of Humacyte. Laura's problem is this: How can you use human cells to create blood vessels that surgeons can pull out of a bag and implant into patients? Although still awaiting FDA approval in the U.S., Humacyte's vessels have already been used to treat wounded soldiers in Ukraine.

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Creating the Second Atomic Age Jun 20, 2024

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As demand for clean energy grows, engineers around the U.S. are working on a new generation of nuclear reactors. These designs reflect how nuclear energy could fit into the power grid – and our lives – in new ways. Yasir Arafat is the Chief Technology Officer at Aalo Atomics. Yasir’s problem is this: How do you mass produce nuclear reactors that are safe, scalable, and cheap?

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