Unlocking The Fountain

Latest Episodes:

Unlocking Bryson's Brain, Episode 8: Two Futures May 24, 2020

Show notes

After months of waiting, the “Bryson mouse” is finally ready for lab tests that will provide new insights into treatments and cures. And Bryson’s parents explore two possible versions of Bryson’s future.

Unlocking Bryson's Brain, Episode 7: Pilgrimage to Boston May 17, 2020

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Bryson’s parents travel to Boston/Cambridge, the global capital for rare disease research. Their goal: to ask private biotech companies to help in their search for a cure. Scientists provide new clues, but also raise difficult questions.

Unlocking Bryson's Brain, Episode 6: The Ethics of Cure May 10, 2020

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Finding a cure for Bryson no longer seems impossible. And that raises new questions about the ethics of this journey. Bryson’s family seeks out new perspectives and learns why “cure” is a loaded term in the disability rights community.

Unlocking Bryson's Brain, Episode 5: Making a Mouse May 03, 2020

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Scientists in Toronto get to work building a mouse with Bryson’s precise genetic variant. Plus, the family travels to Atlanta to provide blood samples for a researcher to create DNA-based “mini-brains” in his lab. Could this cutting edge science provide clues to unlocking Bryson’s brain?

Unlocking Bryson's Brain, Episode 4: A New Hope Apr 26, 2020

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Bryson’s family travels to meet other GRIN1 patients, including Bryson’s GRIN-twin Olivia. And research on mice offers new hope for finding a cure. But a new illness means that the family now needs two medical miracles.

Unlocking Bryson's Brain, Episode 3: The CRISPR Revolution Apr 19, 2020

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Bryson’s parents explore CRISPR, a new technology with the potential to cure dozens of diseases once thought incurable. But gene editing comes with risks — not just for individual patients, but for the human race.

Unlocking Bryson's Brain, Episode 2: Getting a Diagnosis Apr 12, 2020

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From violent seizure-like episodes to insensitive comments from strangers, Bryson has a hard life. But after years of searching, doctors finally provide a diagnosis. The news changes everything for Bryson’s parents and provides a possible path to new treatments — or even a cure.

Unlocking Bryson's Brain, Episode 1: The Mystery Disease Apr 12, 2020

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Bryson seems like a perfectly healthy baby. But soon doctors confirm his parents’ worst fears: something is wrong with Bryson’s brain. Despite dozens of tests over nearly a decade, doctors come up empty in their efforts to find a diagnosis.

Unlocking Bryson's Brain - Trailer Feb 24, 2020

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Bryson is a beautiful, happy boy. But a mysterious illness means he can’t walk, talk, or feed himself. Scientists working at the cutting edge of genetics believe they know what’s causing Bryson’s disease — and think it could be reversed. Motivated by the hope for a cure, Bryson’s parents search for the miracle key that could unlock Bryson’s brain. Hosted by Keith McArthur, coming April 2020.

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