This Week in Virology

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TWiV 569: Smolt'in iron Oct 13, 2019

Show notes

The TWiV pro-vaxxers reveal viruses that infect endangered wild salmon, and how iron in host serum modulates dengue virus acquisition by mosquitoes.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Brianne Barker

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Links for this episode

New viruses that infect endangered wild salmon (eLife)
Host serum iron modulates dengue virus acquisition by mosquitoes (Nat Micro)
Image credit
Letters read on TWiV 569
Timestamps by Jolene. Thanks!

Weekly Science Picks

Brianne - Retraction of new CCR5/lifespan study Alan - Nomad Press illustrated science books, and illustrator Lex Cornell Dickson - RARE: Creatures of the Photo Ark Vincent - The Odyssey of Eradication by Thomas Abraham

Listener Picks

Justin - Mass spec pen Mark - What really brought down the Boeing 737 Max?

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv

TWiV 568: Karolinska viral Oct 06, 2019

Show notes

In the second episode from the Karolinska Institute in Stockholm, Vincent speaks with Jan Albert, Petter Brodin, and Anna Smed-Sörensen about their work on enterovirus D68, systems immunology, and human pulmonary viral infection and inflammation.

Hosts: Vincent Racaniello

Guests: Jan Albert, Petter Brodin, and Anna Smed-Sörensen

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Links for this episode

Karolinska Huddinge
Evolution of enterovirus D68 (Virus Evol)
Maternal anti-viral antibodies in newborns (Nat Med)
Respiratory phagocytes in human influenza (Front Immunol)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv

TWiV 567: Outbreaks and a breakout Sep 29, 2019

Show notes

The TWiV team covers outbreaks of eastern equine encephalitis virus in the US and poliovirus in the Philippines, and explain how a chemokine induced by HIV-1 infection helps release more virus particles from cells.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker

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Links for this episode

Poliomyelitis returns to the Philippines (Mashable, virology blog)
EEE in the USA (Am J Trop Med Hyg)
Chemokine helps HIV-1 release (eLIFE)
Image credit
Letters read on TWiV 567
Timestamps by Jolene. Thanks!

Weekly Science Picks

Brianne - History of infectious disease before/after vaccines Alan - NIH Ham Radio Club Rich - Renewable jet fuel from air Dickson - Newly Discovered Comet Is Likely Interstellar Visitor Kathy - How professors spend their time Vincent - Non-polio enterovirus surveillance network

Listener Picks

Alexey - Periodic Table Podcasts and Videos

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv

TWiV 566: Chicken gumbo and a corona Sep 22, 2019

Show notes

The TWiV team reveals the protein corona that surrounds virus particles and influences infectivity and amyloid aggregation, and a proofreading-impaired herpesvirus that produces quasispecies-like populations.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Guest: Kiki Warren

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Links for this episode

Human fetal tissue research restrictions (The Scientist)
Viral protein corona (Nat Commun)
Proofreading-impaired herpesvirus (Nat Micro)
Phage quasispecies (Cell)
Letters read on TWiV 566
Timestamps by Jolene. Thanks!

Weekly Science Picks

Alan - Astronomy photographer of the year Rich- Urban living leads to high cholesterol... in crows Kiki- Reversal of epigenetic aging Vincent- General Virology by SE Luria

Listener Picks

Sindhu - Sweden Solar System Anthony- Surprising role of viruses in evolution with Eugene Koonin Paul- The Obscure Virus Club

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv

TWiV 565: Karolinska virology Sep 15, 2019

Show notes

From the Karolinska Institute in Stockholm, Vincent speaks with Niklas Björkström, Ali Mirazimi, and Matti Sällberg about their work on the impact of chronic hepatitis C virus infection on NK cells, Crimean-Congo hemorrhagic fever virus vaccines, and immunotherapy to block entry of hepatitis B and D viruses.

Hosts: Vincent Racaniello

Guests: Niklas Björkström, Ali Mirazimi, and Matti Sällberg

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Links for this episode

Karolinska Huddinge
CCHV experimental vaccines (J Virol)
Increased NK function after antiviral cessation (J Inf Dis)
Impact of HCV infection on NK cell repertoire (Nat Comm)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv

TWiV 564: Virology Nobel Prizes with Erling Norrby Sep 08, 2019

Show notes

From the 16th Smögen Summer Symposium on Virology, Vincent speaks with Erling Norrby about how he has used archival material to provide insight into early Nobel Prizes for research on viruses.

Hosts: Vincent Racaniello

Guest: Erling Norrby

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Links for this episode

Swedish Society for Virology
Nobel Prizes and Life Sciences by Erling Norrby
Nobel Prizes and Nature's Surprises by Erling Norrby
Nobel Prizes and Notable Discoveries by Erling Norrby
Nobel Prizes: Cancer, Vision and the Genetic Code by Erling Norrby
Polio and Nobel Prizes (Ann Neurol)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv

TWiV Special: Call me David Tuller Sep 03, 2019

Show notes

David Tuller returns to talk about his efforts of the past year to expose the methodological and ethical problems with the PACE and Lightning trials for therapy of ME/CFS.

Host: Vincent Racaniello

Guest: David Tuller

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Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv

TWiV 563: BLT on mice Sep 01, 2019

Show notes

The TWiVologists consider whether to receive an influenza vaccine in August (in the northern hemisphere), and mice implanted with human lung fragments for studying microbial pathogens.

Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker

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Links for this episode

Waning of influenza vaccine protection (Clin Inf Dis)
Precision mouse models for microbial pathogenesis (Nat Biotech)
Letters read on TWiV 563
Timestamps by Jolene. Thanks!

Weekly Science Picks

Brianne - Why we need to increase diversity in the immunology research community Alan - Stock photos of vaccination that don't suck Kathy- Sample size calculator Vincent- How Economics Shapes Science by Paula Stephan

Listener Picks

Melinda - Zome Tools

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv

TWiV 562: Take a breath Aug 25, 2019

Show notes

TWiV travels to Rutgers University to speak with Brad, Kay, Siobain, and Kim about their careers and their work on viruses of plants, fungi, bacteria, diatoms, and coccolithophores.

Hosts: Vincent Racaniello, Dickson Despommier, and Brianne Barker

Guests: Brad Hillman, Kay Bidle, Siobain Duffy, and Kim Thamatrakoln

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Links for this episode

Viruses of plant-interacting fungi (Adv Virus Res)
Why are RNA virus mutation rates so damn high? (PLoS Biol)
CRESS viruses (Adv Virus Res)
Coccolithovirus facilitation of carbon export in North Atlantic (Nat Micro)
Silicon limitation facilitates virus infection of marine diatoms (Nat Micro)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv

TWiV 561: Hot or not Aug 18, 2019

Show notes

The Autonomous CollecTWiVe reveal two effective treatments for Ebolavirus infection, how a virus in a fungus confers heat tolerance to a plant, and dampened inflammation as a mechanism for bat tolerance to viral infection.

Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker

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Links for this episode