The NFX Podcast

Latest Episodes:

NFXBio: The Promise of Synthetic Embryos with Dr. Jacob Hanna of Renewal Bio Dec 06, 2022

Show notes

We're highlighting a breakthrough moment - this summer, Dr. Jacob Hanna, a professor at the Weizmann Institute of Science published a paper demonstrating that synthetic mouse embryos could be grown outside the womb, without an egg or sperm. This is a major advance that was covered by Nature, The Washington Post, The New York Times, and others. Today, the head of NFXBio Omri Amirav-Drory is sitting down with Dr. Hanna to discuss how we reached this milestone, what it means for science, and how entrepreneurship can help bring this technology out of the lab.

Ep 8: Your Life Is Driven By Network Effects (NFX Masterclass) Nov 30, 2022

Show notes

What city you live in. Who you date or marry. Which job you choose. What clothes you wear. We all think we make these choices ourselves. It certainly feels like we’re in full control. The unseen hand in them all is the networks that surround us and the powerful math they exert on us. This episode outlines how we see network effects impacting nearly every aspect of your life. It will hopefully help you make decisions that are more true to the kind of life you want to lead. This is an audio version of episode 8 from The Network Effects Masterclass, curated for audio and listening on the go. For the full video experience, transcripts, and recommended reading, join the free Network Effects Masterclass at - NFX.com/masterclass.

Ep. 7 - Network Problems Demand Network Solutions (NFX Masterclass) Nov 23, 2022

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We spend a lot of time teaching Founders how to use network effects to create these giant, world-changing businesses, but we think that too little has been said about how society should adapt to these new network effect behemoths we’re helping create. This episode is hosted by general partner James Currier as he discusses how network effect businesses are reshaping the world, why it's our responsibility to design and thoughtfully set up social contracts with our different constituents, and the need to have a perspective about what you are giving and getting from the people on these networks. This is an audio version of episode 7 from The Network Effects Masterclass, curated for audio and listening on the go. For the full video experience, transcripts, and recommended reading, join the free Network Effects Masterclass at - NFX.com/masterclass.

NFXBio: TechBio Platforms Developing a Universal Vaccine & Beating Treatment-Resistant Cancer Nov 22, 2022

Show notes

In biology we have a saying: what doesn’t kill you mutates and tries again. Cancer. Deadly viruses. These problems are so hard to tackle because the goalposts are always moving. Thanks to evolution, these diseases often outpace therapies and vaccines. Today, NFX General Partner and Head of NFX Bio Omri Amirav-Drory is sitting down with two Founders using platforms to stay a step ahead of evolution. Jacob Glanville, Founder of Centivax, has developed a platform to create broad spectrum vaccines capable of arming the immune system against rapidly mutating viruses (like COVID-19 or influenza). Nick Goldner, Founder of resistanceBio, discusses his approach for mapping all the possible resistance paths a cancer can take in the human body – and developing therapies to shut those escape routes down. Here’s why we need platforms to tackle biology’s biggest problems, what it takes to build a platform company, and their advice for fundraising in Techbio.

Ep. 6 - Case Studies: Network Effects In Action (NFX Masterclass) Nov 18, 2022

Show notes

These are case studies and stories that outline network effects in the wild - it is a montage of how big tech companies like Trulia, Meta, Uber, and even Bitcoin navigate their defensibility over time. For the best experience of this episode, watch our case studies at nfx.com/masterclass or by searching on YouTube to get the visual side of these deep dives. That was episode 6 of 11, from the Network effects masterclass. Stay tuned and subscribe as next up is Ep. 7 - Network Problems Demand Network Solutions, here on the NFX podcast. This is an audio version of episode 6 from The Network Effects Masterclass, curated for audio and listening on the go. For the full video experience, transcripts, and recommended reading, join the free Network Effects Masterclass at - NFX.com/masterclass.

Ep. 5 - Network Bonding Theory (NFX Masterclass) Nov 09, 2022

Show notes

Realize that your startup itself is a network. Your goal is to bond people to it. When you attach, or bond, one node to your network, it adds value to all the other nodes. This is episode 5, from the NFX Masterclass, covering Network Bonding Theory. Learn best practices for bonding nodes to your network led by NFX General Partner James Currier as he shows you a set of mechanisms that will help you build network effects startups even better. This is an audio version of episode 5 from The Network Effects Masterclass, curated for audio and listening on the go. For the full video experience, transcripts, and recommended reading, join the free Network Effects Masterclass at - NFX.com/masterclass.

Ep. 4 - The 4 Pillars of Defensibility (NFX Masterclass) Oct 26, 2022

Show notes

Durability = Network Effects + Economies of Scale + Brand + Embedding + IP. Learn about these other 4 strategies for startup durability outside of network effects from NFX General Partner, Pete Flint. Value creation mostly accrues in the out-years when usage, revenue, and growth compound. Founders who win big spend more time at the beginning on creating products and business mechanisms that follow these five durability factors and thus drive increasing returns at scale. This is an audio version of episode 4 from The Network Effects Masterclass, curated for audio and listening on the go. For the full video experience, transcripts, and recommended reading, join the free Network Effects Masterclass at - NFX.com/masterclass.

Ep. 3 - Mapping Out the 16 Network Effects (NFX Masterclass) Oct 19, 2022

Show notes

Unlock the NFX map to understand how each network effect works — in episode 3 of the Network Effects Masterclass, General Partner James Currier will review the 16 types of network effects and how they reinforce each other in powerful ways. Learn to analyze the NFX map to determine how to engineer sustained, long-term growth into your startup. This is an abridged version of episode 3 from The Network Effects Masterclass, curated for audio and listening on the go. For the full video experience, transcripts, and recommended reading, join the free Network Effects Masterclass at - NFX.com/masterclass.

Ep. 2 - The Underlying Properties Of Network Theory (NFX Masterclass) Oct 12, 2022

Show notes

Unlearn what you thought you knew about network effects. This episode takes you to the very beginning and lays out network theory from square one. Listen in as James covers the basics of network principles to use as a launchpad for the rest of the course and see how your startup behaves as a network itself. This is an abridged version of episode 2 from The Network Effects Masterclass, curated for audio and listening on the go. For the full video experience, transcripts, and recommended reading, join the free Network Effects Masterclass at - NFX.com/masterclass.

Ep. 1 - Why Network Effects Are Mission Critical (NFX Masterclass) Oct 05, 2022

Show notes

Few understand the hidden complexities of network effects - learn all there is to know about building iconic companies from day one. This is episode 1 of the Network Effects Masterclass (audio edition). You'll hear a short introduction from NFX Partner James Currier on what you will learn in this masterclass to build your company into the next world-class startup and understand why network effects are the #1 advantage in driving exponential growth. This is an abridged version of episode 1 from The Network Effects Masterclass, curated for audio and listening on the go. For the full video experience, transcripts, and recommended reading, join the free Network Effects Masterclass at - NFX.com/masterclass. Stay tuned for weekly episodes until we finish the course.

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