The Inner Workings of Cells, Winter 2008

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Science & Medicine
**The Inner Workings of Cells, Winter 2008**

Cellular function lies at the root of all complex and simple biological systems. This course will expose you to the fundamental mechanisms that allow cells to maintain the system of proteins and biomolecules required for them to replicate with high fidelity, to maintain stable functional states, to differentiate in response to external cues and to ultimately form complex organizations of cells (i.e., tissues). We will apply an experimental approach to a classic problem in cell biology. We will master “blackboard” experimental techniques to allow us to explore the remarkable transformation of a monolayer of cells after being “wounded.” Under such conditions, cells surrounding the wound change their organization and programming in order to migrate, divide, and differentiate to fill in the wound.

Latest Episodes:

Review for Final Exam Mar 21, 2008

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Review for Final Exam: This class covers all topics discussed in the course, with an emphasis on cell signaling.

Cell Signaling & Cancer Cells Mar 17, 2008

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Lecture 28: The instructor reviews some major pathways dealing with signal transduction and an application of principles learned to cancerous cells.

Signal Transduction Mar 14, 2008

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Lecture 27: Kaplan continues his discussion of signal transduction, the role of signals in cell migration, and the ability of cells to see which direction to move.

Signal Transduction Mar 12, 2008

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Lecture 26: Kaplan talks about properties of signaling modules and different kinds of membrane receptors that interpret signals from outside the cell.

Cell Signaling Mar 10, 2008

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Lecture 25: This class is a wrap-up of cell division and checkpoints in the regulatory cycle, and introduction to how cells interpret various biochemical signals.

Cell Division Mar 07, 2008

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Lecture 24: Students learn more about cell division, and introduction to cell checkpoints along the regulatory cycle.

Review for Midterm 2 Mar 04, 2008

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Review for Midterm 2: This covers protein trafficking, the cytoskeleton and cell division.

Regulation of Cell Division Mar 03, 2008

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Lecture 22: This is a continued discussion of the regulation of cell division -- how mitosis is coordinated within the cell.

Cell Division Feb 29, 2008

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Lecture 21: The stages of the cell cycle, the regulatory cycle, and biochemical switches involved in these two cycles are covered.