The Incubator

Latest Episodes:

#NEC SYMPOSIUM - 👨‍⚕️ Dr. Martin Blakely - Diving into the World of Pediatric Surgery and NEC Research: The Vital Role of Collaboration Aug 29, 2023

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We have the privilege of engaging with renowned Dr. Martin Blakely from Vanderbilt University Medical Center. Dr. Blakely, a passionate advocate for improving the outcomes of Necrotizing Enterocolitis (NEC), sheds light on how patient weight and illness severity factor into treatment decisions. He also presents valuable learnings from randomized trials that have evaluated the initial choice of laparotomy or drainage for NEC diagnosis. As an active board member of the NEC Society, Dr. Blakely shares his relentless pursuit for improved NEC outcomes through ground-breaking research.
We unmask the importance of collaborative work in the realm of medical research. We unravel the significance of protocol development and the critical role it plays in advancing neonatology and pediatric surgery. The discussion highlights the essence of a multi-disciplinary approach involving various healthcare professionals like radiologists. So, tune in for a riveting journey into the world of pediatric surgery and research.

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As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

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#NEC SYMPOSIUM - 📚 Ravi Patel - Untangling the Complexities of NEC Management & Advocating Probiotic Use for Prevention Aug 29, 2023

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Get ready to be enlightened as we sit down with the insightful Ravi Patel, a key figure in the Neck Society, to untangle the complexities of Necrotizing Enterocolitis (NEC) management. Tune in to hear Patel's take on the pressing need for standardized care amidst the uncertainties of NEC treatment; he shares thought-provoking insights into the duration of antibiotic treatment and the timing of feeding resumption. As we journey back in time, Patel offers a fascinating perspective on the historical context of antibiotic choices and the hurdles of decision-making in a landscape devoid of recent trials.

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#NEC SYMPOSIUM - 👩‍⚕️ Dr. Susan Hintz - Amplifying Family Voices in NEC Advocacy and Exploring Long-term Outcomes Aug 29, 2023

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What if we told you that the family's voice could change the face of necrotizing enterocolitis (NEC) advocacy and treatment? Well, that's exactly what we're diving into with our special guest, Dr. Susan Hintz. As we dig into the inspiring sessions from the NEC symposium, we reflect on the immense power of a strong partnership between parents and medical professionals. Dr. Hintz shares insights on risk factors and the ways we can enhance our support for families navigating this condition. Additionally, we spotlight the incredible advocative work of Kim Novod and Jen Canvasser, who've transformed the world of NEC care through their relentless efforts.
As we move to the latter part of our discussion, we pose a critical question - are we truly understanding the long-term outcomes of NEC? We challenge the conventional two-year outcomes and advocate for a more comprehensive understanding of the implications on families in the long run. Dr. Hintz, during her enlightening session at the NEC Symposium, emphasizes the importance of meaningful questions and outcomes that resonate with families and survivors. We circle back to episode 106 of the Incubator podcast, highlighting the crucial aspect of neurological outcomes and long-term impacts into adulthood. As we wrap up, we take a moment to salute the mentors who've molded our understanding of NEC and motivated us to continually strive for better outcomes for families.

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#146 - NEC SYMPOSIUM 2023 - 👨‍💼 Mark Del Monte - The Power of Advocacy and Storytelling in Transforming Pediatrics Aug 28, 2023

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Would you believe it if we told you that advocacy is as integral to Pediatrics as medical science and clinical care? That's what Mark Del Monte, the dynamic CEO and Executive VP of the American Academy of Pediatrics, brings to the table in this enlightening conversation. The power of individual stories, the quest for small wins, and the importance of creating moments for change are just some of the riveting insights Mark shares, underlining that advocacy isn't just a side aspect, but a crucial part of the mix that propels the field of Pediatrics forward.
We find out why Mark is a firm believer in the transformative power of storytelling in the realm of child health advocacy. Drawing from history, Mark elucidates how stories have been instrumental in stirring change and why it’s pivotal for organizations like the AAP to assert their presence at venues like the NEC symposium. In the end, he leaves us with a powerful notion: advocacy is a series of moments that, together, create a brighter future for children and families. You don't want to miss this one; join us as we explore the multidimensional world of Pediatrics with Mark Del Monte.

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NEC SYMPOSIUM - Open Mic with Daphne, John and Shetal Aug 28, 2023

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Will you stay in research? That's the question facing many young scientists today. We've invited Daphne, a young scientist who found her answer through the NEC Society Mentorship Program where she was paired with Dr. Misty Good. They regularly meet to discuss their shared passion for studying necrotizing enterocolitis.
https://necsociety.org/nec-society-research-incubator/

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NEC SYMPOSIUM - 🙋‍♀️ Erin Umberger - From Tragedy to Advocacy: A Discussion on NEC Awareness Aug 28, 2023

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Have you ever felt the power of a story? That's exactly what unfolded in our heartfelt conversation with Erin as she shared her profound personal journey with necrotizing enterocolitis (NEC). Her world was turned upside down when baby Sarah, born prematurely and diagnosed with NEC, tragically passed away. This devastating loss sparked a mission in Erin. Her dedication to raising awareness about this life-threatening disease is a testament to her strength and resilience.
To conclude our conversation, we tackled a topic often overlooked - the need for robust support for bereaved parents and families. Our guests illuminated how essential it is to continue care for the family unit after the loss of a baby. We also examined the profound impact of small acts of kindness from healthcare providers. Erin’s heartfelt appreciation for the caregivers in the NICU was palpable, reminding us of the precious lives we are fighting for and reinforcing the importance of sharing stories like Sarah's. So join us, as we navigate the challenging terrain of NEC, and explore how each of us can contribute to this vital cause.

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NEC SYMPOSIUM 2023 - 👩‍⚕️ Dr. Aloka Patel - Unveiling Racial Disparities in Breastfeeding and Innovative Strategies Aug 28, 2023

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Ever pondered how societal factors, not just medical ones, could significantly influence breastfeeding patterns? Dr. Aloka Patel joins us for an eye-opening dialogue pinpointing racial disparities in breastfeeding, especially in NICU scenarios. With her profound knowledge and passion, she makes us comprehend how educating staff, consistent communication about the sundry benefits of breastmilk, and ensuring resource availability could remarkably enhance the breastfeeding culture.
This episode will take you through an emotional voyage as we uncover the struggles faced by mothers striving to produce sufficient milk for their infants. The spotlight is thrown on the disparities between Black and White mothers. Listen to Dr. Patel's riveting narratives about the innovative interventions on the anvil to alleviate the burden of providing breast milk. From offering breast pumps, milk couriers to compensating mothers for their time and milk, these strategies promise to revolutionize the experience of breastfeeding. The anecdotes from Dr. Patel's life underscore her dedication to reducing obstacles to breastfeeding.
In a key segment of our discussion, we touch upon our societal tardiness in initiating dialogues about breastfeeding. Hear about an innovative pilot project in Chicago schools aimed at demystifying breastfeeding. The project engaging boys and girls in the fifth grade has received an overwhelmingly positive response. Our conversation isn't complete without emphasizing the significant role of advocacy work and neonatologists in community outreach. So, lend us your ears and join us in the journey to normalize breastfeeding.

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🎙️ Live from the Nec Symposium - Interviews, updates, and insights from the conference Aug 28, 2023

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Step right into the buzzing hub of the NEC Symposium in San Diego as we take our show on the road for the first time! Amidst the infectious energy of a live conference, we share enlightening conversations filled with fascinating updates on neck research, care, and advocacy efforts from non-profit organizations with a vision of a world without NEC. Be privy to exclusive interviews with keynote speaker Dr. Gail Bestner, chief of pediatric surgery at Nationwide, as she provides intriguing insights on a probiotic that combats infection.
We've pitched our recording setup just outside the Exhibitor Hall, soaking in the conference's electric atmosphere and connecting with passionate attendees. You'll hear daily updates, personal stories from families at the heart of our mission, and much more. Plus, if you're in the vicinity, don't hesitate to drop by for a chat - we'd love to hear from you! Even if you can't join us physically, we promise to keep the heartbeat of this vibrant event alive for you.

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#145- 👩‍⚕️ Dr. Gail Besner - Pioneering Strategies to Combat Necrotizing Enterocolitis Aug 28, 2023

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Ever imagined a world without the devastating disease, Necrotizing Enterocolitis? Dr. Gail Bestner, a chief of pediatric surgery at Nationwide Children's Hospital, passionately shares her innovative therapeutic strategies that could make this a reality. Join us for an enlightening conversation as we explore the use of probiotics in neonatology, the challenges of implementing probiotic therapy in a neonatal intensive care unit, and how the right approaches could steer us towards a world free from Necrotizing Enterocolitis.
We throw the spotlight on a groundbreaking strategy for administering probiotics in their biofilm state, a significant detour from current practices. The exciting discussion takes us through the benefits of lactobacillus ruteri, the ingenious technique of loading microspheres with prebiotic substances, and the inspiring inception story of this research project. We move beyond the realm of Necrotizing Enterocolitis to delve into Dr. Bestner's notable work on autism treatment, discussing the importance of the gut-brain axis and the use of a pig model in her pioneering research.
As we traverse the multifaceted world of clinical research, we touch upon the entrepreneurial side of drug development and the crucial role of NIH grants. We also discuss the importance of a multidisciplinary approach in caring for babies affected by Necrotizing Enterocolitis, emphasizing early detection and the potential of biomarkers. Dr. Bestner's compelling advice for aspiring clinicians and researchers, along with her passionate advocacy for Necrotizing Enterocolitis, wraps up this captivating episode that is a perfect blend of science, passion, and hope for a healthier future. Tune in and get inspired!

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#144 - 📑 Journal Club - no more car seat tests?, rethinking magnesium for neuroprotection, shortened human milk fortification and more Aug 20, 2023

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Hello friends 👋

We have a great episode of journal club for you this week. We talk about feed fortification, magnesium for neuroprotection, car seat testing and much more. We also have a new edition of the EBNEO article of the month commentary this week. We hope you enjoy this episode.

Have a nice Sunday!

You can find the articles discussed on today's episode below 👇

Early Human Milk Fortification in Infants Born Extremely Preterm: A Randomized Trial. Salas AA, Gunawan E, Nguyen K, Reeves A, Argent V, Finck A, Carlo WA.Pediatrics. 2023 Aug 8:e2023061603. doi: 10.1542/peds.2023-061603. Online ahead of print.PMID: 37551512

Sooner Is Better: Early Human Milk Fortification for Hospitalized Preterm Infants <29 Weeks. Belfort MB.Pediatrics. 2023 Aug 8:e2023062391. doi: 10.1542/peds.2023-062391. Online ahead of print.PMID: 37551455

Prenatal Intravenous Magnesium at 30-34 Weeks' Gestation and Neurodevelopmental Outcomes in Offspring: The MAGENTA Randomized Clinical Trial. Crowther CA, Ashwood P, Middleton PF, McPhee A, Tran T, Harding JE; MAGENTA Study Group.JAMA. 2023 Aug 15;330(7):603-614. doi: 10.1001/jama.2023.12357.PMID: 37581672

Discontinuation of Car Seat Tolerance Screening and Postdischarge Adverse Outcomes in Infants Born Preterm. Braun D, Kaempf JW, Ho NJ, Nguyen MH, Passi R, Burgos AE, Volodarskiy M, Villosis MFB, Gupta M, Habeshian TS, Tam HK, Litam KB, Hong QL, Dong CC, Getahun D.J Pediatr. 2023 Jun 22;261:113577. doi: 10.1016/j.jpeds.2023.113577. Online ahead of print.PMID: 37353144

Discontinuing Predischarge Car Seat Tolerance Tests: Is it too Premature? Shah MD.J Pediatr. 2023 Aug 2:113663. doi: 10.1016/j.jpeds.2023.113663. Online ahead of print.PMID: 37541426

Antenatal Magnesium Sulfate and adverse gastrointestinal outcomes in Preterm infants-a systematic review and meta-analysis. Prasath A, Aronoff N, Chandrasekharan P, Diggikar S.J Perinatol. 2023 Jun 30. doi: 10.1038/s41372-023-01710-8. Online ahead of print.PMID: 37391507

This week, we are thrilled to welcome Dr. Dustin Flannery for our monthly EBNEO article of the month commentary written in collaboration with Dr. Alvaro Proaño

Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants. Kampmann B, Madhi SA, Munjal I, Simões EAF, Pahud BA, Llapur C, Baker J, Pérez Marc G, Radley D, Shittu E, Glanternik J, Snaggs H, Baber J, Zachariah P, Barnabas SL, Fausett M, Adam T, Perreras N, Van Houten MA, Kantele A, Huang LM, Bont LJ, Otsuki T, Vargas SL, Gullam J, Tapiero B, Stein RT, Polack FP, Zar HJ, Staerke NB, Duron Padilla M, Richmond PC, Koury K, Schneider K, Kalinina EV, Cooper D, Jansen KU, Anderson AS, Swanson KA, Gruber WC, Gurtman A; MATISSE Study Group.N Engl J Med. 2023 Apr 20;388(16):1451-1464. doi: 10.1056/NEJMoa2216480. Epub 2023 Apr 5.PMID: 37018474

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