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    Science

    The Incubator

    A weekly discussion about new evidence in neonatal care and the fascinating individuals who make this progress possible. Hosted by Dr. Ben Courchia and Dr. Daphna Yasova Barbeau.

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    Copyright: © 2022 CATO NEONATAL INNOVATIONS INC.

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    Latest Episodes:
    #297 - [Journal Club Shorts] - 📌 Neonatal intermittent hypoxemia events are associated with later systemic hypertension. Apr 06, 2025
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    Neonatal intermittent hypoxemia events are associated with later systemic hypertension.

    Martinez S, Chen Z, Di Fiore JM, Nguyen C, Minich NM, Hibbs AM.Pediatr Res. 2025 Jan 31. doi: 10.1038/s41390-025-03881-w. Online ahead of print.PMID: 39885241

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #297 - [Journal Club Shorts] - 📌 Short Duration of Antenatal Corticosteroid Exposure and Outcomes in Extremely Preterm Infants. Apr 06, 2025
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    Short Duration of Antenatal Corticosteroid Exposure and Outcomes in Extremely Preterm Infants.

    Chawla S, Wyckoff MH, Lakshminrusimha S, Rysavy MA, Patel RM, Chowdhury D, Das A, Greenberg RG, Natarajan G, Shankaran S, Bell EF, Ambalavanan N, Younge NE, Laptook AR, Pavlek LR, Backes CH, Van Meurs KP, Werner EF, Carlo WA; National Institute of Child Health and Human Development (NICHD) Neonatal Research Network (NRN).JAMA Netw Open. 2025 Feb 3;8(2):e2461312. doi: 10.1001/jamanetworkopen.2024.61312.PMID: 39982720 Free PMC article.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #297 - [Journal Club Shorts] - 📌 Evaluating decision regret after extremely preterm birth. Apr 06, 2025
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    Evaluating decision regret after extremely preterm birth.

    Belden L, Kaempf J, Mackley A, Kernan-Schloss F, Chen C, Sturtz W, Tomlinson MW, Guillen U.Arch Dis Child Fetal Neonatal Ed. 2025 Feb 21;110(2):191-199. doi: 10.1136/archdischild-2024-327287.PMID: 39164062

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #297 - [Journal Club Shorts] - 📌 Response to Inhaled Nitric Oxide and Mortality Among Very Preterm Neonates With Pulmonary Hypertension. Apr 06, 2025
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    Response to Inhaled Nitric Oxide and Mortality Among Very Preterm Neonates With Pulmonary Hypertension.

    Baczynski M, Weisz D, Thomas L, Fevrier S, Castaldo M, Soraisham A, Hyderi A, Agarushi R, Bhattacharya S, Lalitha R, Sidhu A, Abdul Wahab MG, Altit G, Hébert A, Louis D, Elsayed Y, Mitra S, Deshpande P, Kharrat A, Zhu F, Ting J, Yoon E, Shah PS, Jain A; Canadian Neonatal Network Investigators.JAMA Netw Open. 2025 Feb 3;8(2):e2458843. doi: 10.1001/jamanetworkopen.2024.58843.PMID: 39928335 Free PMC article.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #296 - Understanding Delirium in the NICU Apr 02, 2025
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    Delirium in the NICU is an under-recognized and under-assessed challenge. In this episode of The Incubator Podcast, Ben and Daphna sit down with Dr. Karishma Rao and clinical pharmacist Alex Oschman from Children’s Mercy Hospital to explore the complexities of neonatal delirium. Drawing on their collaborative work and recent publication in Frontiers in Pharmacology, they unpack the nuances of distinguishing delirium from pain, agitation, withdrawal, and sedation—particularly in medically complex, long-stay infants.

    The conversation highlights the limitations of current assessment tools, such as the CAPD (Cornell Assessment of Pediatric Delirium), and the barriers to implementation in the NICU setting. The team shares practical strategies, including modifying pain and withdrawal protocols, minimizing deliriogenic medications like benzodiazepines and opioids, and emphasizing non-pharmacological interventions like early mobility, sleep hygiene, and environmental optimization.

    They also discuss pharmacologic options when needed, such as the selective use of atypical antipsychotics like quetiapine or risperidone, and raise critical questions about how developmental care might reduce the need for sedation altogether. This episode is a call to action for NICU teams to better understand, assess, and address delirium in our most vulnerable patients through collaborative, multidisciplinary care.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #295 – 🗞️ NeoNews: Vaccine Schedule, Birthright, Trust in our Doctors, and more… Mar 30, 2025
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    In this packed episode of Neo News, Eli, Ben, and Daphna dive into the headlines impacting neonatology and public health. The trio starts with the controversial confirmation of Robert F. Kennedy Jr. as head of HHS, analyzing his actions around the CDC, NIH, vaccine policy, and the implications of promoting “informed consent” messaging in place of public health advocacy. Drawing from reporting by The New York Times, STAT News, and Science Magazine, the team unpacks how these shifts could affect vaccine uptake in the NICU.

    Next, they examine the threat to birthright citizenship in the U.S., based on analysis from The New York Times, and how immigration policy may directly impact NICU families’ access to care and trust in healthcare systems.

    They also discuss a Wall Street Journal article detailing the erosion of trust in physicians post-pandemic and the fallout from a recent JAMA Pediatrics study on therapeutic hypothermia in late preterms, which raised questions about research transparency.

    Other highlights include studies from Scientific Reports, JAMA Network Open, and The New York Times on air pollution, paternity leave, language-concordant care, and breastfeeding. The show ends with a call to action from Dr. Shadel Shah’s op-ed advocating for the continuation of the PREEMIE Act.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #292 - Neonatology Staffing Practices (ft WiN Group) Mar 23, 2025
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    In this week’s episode, Daphna hosts a powerful roundtable featuring Drs. Kerri Machut, Milenka Cuevas-Guaman, Emily Miller, Christine Bishop, and Christiane Dammann—leaders of a national effort to improve neonatology staffing. Together, they share insights from their recently developed recommendations, created through a Delphi consensus process and supported by a strategic grant from the AAP Section on Neonatal-Perinatal Medicine. These evidence-informed guidelines aim to promote safer, more sustainable, and more transparent staffing models in NICUs across the country. The team discusses key themes including defining clinical FTEs in hours per year, ensuring flexible scheduling, protecting time for scholarly and administrative work, and how to advocate for systemic change. Notably, these landmark recommendations have been accepted for publication in the journal Pediatrics and will be available online in May 2025. Listeners will also learn about an upcoming toolkit designed to help individuals and institutions apply these recommendations in practice. Whether you’re a practicing neonatologist, a trainee, or in a leadership role, this conversation offers timely solutions to address burnout, support workforce well-being, and ultimately improve care for the smallest and sickest patients.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #290 – 🫀 From the Heart - Preemies with CHD, Post op Brain Injury & The Neonatologist’s Role in Cardiac Care Mar 16, 2025
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    In this episode of From The Heart, hosts Dr. Nim Goldshtrom and Dr. Adrianne Bischoff explore the latest research in neonatal cardiac care, focusing on congenital heart disease (CHD) and its impact on premature infants. They discuss a study analyzing survival trends in preterm infants with CHD, highlighting the “double jeopardy” these babies face due to both prematurity and congenital cardiac anomalies. Another study compares neurodevelopmental outcomes between preterm infants and those with CHD, revealing that term infants with CHD exhibit similar motor and cognitive challenges as preterm infants, yet receive less developmental support. The conversation then shifts to emerging research showing a decline in postoperative brain injuries in CHD patients, possibly due to improved surgical and perioperative care. Finally, they discuss a survey on neonatal cardiac care models, emphasizing the evolving role of neonatologists in managing CHD patients and the need for better integration between NICUs and CICUs. Nim and Adrianne reflect on the importance of specialized care teams, advocating for neonatologists to play a greater role in optimizing outcomes for this vulnerable population. Tune in for a compelling discussion on bridging the gaps in neonatal cardiac care.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #290 - [Journal Club Shorts] - 🫀 Integrated cardiac care models of neonates with congenital heart disease: the evolving role of the neonatologist. Mar 16, 2025
    Show notes

    Send us Fan Mail

    Integrated cardiac care models of neonates with congenital heart disease: the evolving role of the neonatologist.

    Hamrick SEG, Ball MK, Rajgarhia A, Johnson BA, DiGeronimo R, Levy PT; Children’s Hospital Neonatal Consortium (CHNC) Cardiac Focus Group.J Perinatol. 2021 Jul;41(7):1774-1776. doi: 10.1038/s41372-021-01117-3. Epub 2021 Jun 17.PMID: 34140645 No abstract available.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #290 - [Journal Club Shorts] - 🫀 Declining Incidence of Postoperative Neonatal Brain Injury in Congenital Heart Disease. Mar 16, 2025
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    Declining Incidence of Postoperative Neonatal Brain Injury in Congenital Heart Disease.

    Peyvandi S, Xu D, Barkovich AJ, Gano D, Chau V, Reddy VM, Selvanathan T, Guo T, Gaynor JW, Seed M, Miller SP, McQuillen P.J Am Coll Cardiol. 2023 Jan 24;81(3):253-266. doi: 10.1016/j.jacc.2022.10.029.PMID: 36653093 Free PMC article.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


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