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    Science

    The Incubator

    A weekly discussion about new evidence in neonatal care and the fascinating individuals who make this progress possible. Hosted by Dr. Ben Courchia and Dr. Daphna Yasova Barbeau.

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    Copyright: © 2022 CATO NEONATAL INNOVATIONS INC.

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    Latest Episodes:
    #376 - 💡 Rethinking Phototherapy – Drafting the New AAP Guidelines with Dr. Alex Kemper Nov 16, 2025
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    In this episode of The Incubator Podcast, Ben and Daphna sit down with Dr. Alex Kemper, Division Chief of Primary Care Pediatrics at Nationwide Children’s Hospital and Editor-in-Chief of Pediatrics. Dr. Kemper served as chair of the American Academy of Pediatrics subcommittee that authored the 2022 revision of the neonatal hyperbilirubinemia guidelines.

    Together, they explore the motivations behind revisiting the 2004 guideline, the major changes introduced, and how these revisions are shaping clinical care. Dr. Kemper explains why treatment thresholds for phototherapy were raised, the careful balance between avoiding unnecessary interventions and preventing kernicterus, and the rationale for moving away from the risk stratification nomogram. The discussion highlights phototherapy as an effective but not benign therapy—one that can disrupt bonding, prolong hospitalization, and create family stress when overused.

    Listeners will gain insight into the complexities of evidence review, the challenges of consensus-building over eight years of work, and the importance of shared decision-making and reliable follow-up after discharge. This conversation not only demystifies the new guidelines but also reframes the way clinicians think about jaundice management, risk stratification, and the broader impact on families.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #375 - 🟠 CHNC 2025 COVERAGE - What's big about tiny babies? Nov 13, 2025
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    In this discussion, Dr. Hevil Shah (Cook Children’s Hospital) and Dr. Julie Lindower (UI Children’s) highlight the work of the CHNC Focus Group on Extremely Preterm Infants, centered on babies born between 21–23 weeks’ gestation. They share insights from a workshop on precision care, emphasizing lessons from Iowa’s long-term data showing improved survival and neurodevelopmental outcomes. The conversation explores variability in resuscitation and counseling practices across centers, and the importance of unified messaging among care teams. The group’s next steps include publishing survey results and strengthening collaborations—particularly with the nutrition focus group—to advance standardized, evidence-based care for the most premature newborns.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #375 - 🟠 CHNC 2025 KEYNOTE - We must welcome open discussions on reproductive health Nov 13, 2025
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    In this keynote discussion, Dr. Natasha Henner (Lurie Children’s Hospital) examines how evolving reproductive policies are reshaping neonatal practice, from counseling at the limits of viability to supporting families after restrictive abortion laws. She discusses rising NICU admissions for infants with congenital differences, ethical tensions around “life-limiting” diagnoses, and gaps in perinatal hospice and home care resources. Dr. Henner emphasizes the need for shared frameworks among neonatologists, obstetricians, and palliative care teams, as well as simulation-based training to navigate moral distress and complex communication. Her call to action: welcome these difficult conversations to improve compassionate, coordinated family-centered care.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #375 - 🟠 CHNC 2025 KEYNOTE - Mental Health Support from Heartbeat to Home Nov 12, 2025
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    In this keynote conversation, Dr. Amy Baughcum, PhD (Nationwide Children’s), Dr. Elizabeth Fischer, PhD (Children’s Wisconsin), and Dr. Lamia Soghier, MD, MeD, MBA (Children’s National) discuss building comprehensive perinatal mental health support systems that span from prenatal diagnosis to life after NICU discharge. Drawing inspiration from Dr. Joanna Cole’s fetal psychology model at CHOP, they emphasize early screening, interdisciplinary collaboration, and embedding psychologists or social workers within NICU teams. The speakers highlight strategies to normalize emotional distress, empower families to seek help, and align institutional priorities with psychosocial care. Their shared message: supporting parental mental health is essential, evidence-based, and foundational to optimal infant outcomes.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #375 - 🟠 CHNC 2025 COVERAGE - You can't walk through water without getting wet Nov 12, 2025
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    This episode addresses NICU staff mental health with Dr. Chavis Patterson, PhD (Children’s Hospital of Philadelphia). He reviews common problems—toxic stress, compassion fatigue, irritability, sleep disturbance—and practical mitigation strategies: brief micro-practices (five-minute arrival/departure routines), peer debriefs (e.g., “pink flags”), unit multidisciplinary check-ins, and institutional resources such as employee assistance programs and embedded NICU psychologists. Patterson stresses normalizing emotional responses, reducing stigma around seeking psychotherapy, and building structural supports by advocating for funded on-unit psychology positions. Immediate actions: start regular team debriefs, map local mental-health resources, pilot embedded psychology coverage, and lead institutional advocacy to make staff mental health standard NICU practice.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #375 - 🟠 CHNC 2025 KEYNOTE - Can we make baby lungs more resilient? Nov 12, 2025
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    This keynote episode features Dr. Jennifer Sucre (Vanderbilt University Medical Center), whose research bridges bedside observation and molecular biology to uncover why some preterm infants develop severe bronchopulmonary dysplasia (BPD) while others recover. Through innovative live imaging of lung development and mouse and human tissue models, her lab discovered that capillary “guidance” signals—semaphorins—are crucial for lung repair and resilience. Loss of these pathways marks irreversible injury. Dr. Sucre emphasizes “bedside-to-bench” science, finding lessons from resilient infants to inform therapy. Clinically, she urges providers to recognize individual resilience, foster hopeful communication with families, and envision a future where BPD is preventable—not inevitable.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #375 - 🟠 CHNC 2025 COVERAGE - The cumulative effect of prematurity and CHD Nov 12, 2025
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    This episode features Dr. Giulia Lima (Boston Children’s Hospital), a CHNC Mentored Fellow, discussing risk factors for morbidity and mortality among preterm infants with congenital heart disease (CHD) using data from over 11,000 NICU admissions. Surprisingly, older gestational age did not predict improved survival once infants survived beyond three days. Major mortality predictors included surgical NEC, bloodstream infection, trisomy 21, airway anomalies, and compromised systemic output lesions. Multiple gestation appeared protective, though reasons remain unclear. Dr. Lima highlights the importance of standardized prenatal steroids, care coordination, and exploring socioeconomic and ethnic disparities to improve outcomes in this uniquely vulnerable CHD population.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #375 - 🟠 CHNC 2025 COVERAGE - EXPLORE projects HOT TOPICS! CAKUT risk calculator and TH in the 33-35 weeks GA! Nov 12, 2025
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    This episode features Dr. Sofia Isabel Perazzo (Children’s National Hospital) and Dr. Rakesh Rao (St. Louis Children’s Hospital) discussing a CHNC Explore analysis of intestinal stricture formation following surgical necrotizing enterocolitis (NEC). Using 15 years of CHND data, they examined over 2,400 surgical NEC cases, finding an overall stricture incidence of about 31%, with striking inter-center variability (24–38%). Lower gestational age, stoma creation, and combined drainage-laparotomy increased risk, while peritoneal drainage was protective. Hispanic ethnicity was associated with lower risk. Although their predictive model (AUC 0.67) was modest, the findings offer valuable benchmarks for parent counseling, quality improvement, and hypothesis generation.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #375 - 🟠 CHNC 2025 COVERAGE - Stricture formation after Surgical NEC Nov 12, 2025
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    In this episode Dr. Murali Premkumar (Texas Children’s) presents an Explore/CHNC analysis of stricture formation after surgical NEC using 2010–2024 CHND data (2,411 surgical NEC infants). Overall CHNC stricture incidence ≈31% with marked inter-center variability (adjusted center rates ~24–38%). Multivariable analysis identified lower gestational age and stoma/laparotomy as associated with higher stricture risk, while initial peritoneal drainage associated with lower risk; Hispanic ethnicity showed lower unadjusted risk. A predictive model yielded AUC 0.67, highlighting missing variables (antibiotic duration, feeding practices). Practical implications: use these benchmarks to counsel families, generate hypotheses, and target QI by studying low-risk centers.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


    #375 - 🟠 CHNC 2025 COVERAGE - The Nuances of Universal Screening Programs Nov 11, 2025
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    This episode features Dr. Sarah Swenson (Children’s Nebraska), Dr. Cara Solness, PhD (Children’s Nebraska), and Dr. Desiree Leverette (Emory/Children’s Healthcare of Atlanta) discussing equitable approaches to parental mental health screening in the NICU. They highlight that traditional programs often screen only mothers for depression, missing significant distress among non-gestational parents, especially fathers. Universal screening identified five times more affected partners, improving opportunities for support. The guests underscore the developmental importance of including all caregivers, the need to address stigma and fears of CPS involvement, and the value of trauma-informed communication. They advocate for integrated NICU psychologists and tailored, equity-focused interventions, including telehealth and culturally responsive materials.

    Support the show

    As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

    Enjoy!


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