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DemystifySci is Dr. Michael Shilo DeLay and Dr. Anastasia Bendebury. Together they untangle complex theories of nature, making analysis accessible through conversations with exceptional thinkers. Each week they interview a new theorist about the ideas that are going to rewrite our understanding of the world. Power them via Patreon: @demystifysci
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What does the future of medicine look like? Precision, precision, precision. In the last few decades, neuroengineers have largely relied on optogenetics to achieve single neuron precision, but widespread application in the clinical setting has been hindered by the fact that to get the tech to work you have to have a light in the brain. Which is... invasive, to say the least. Enter magnetogenetics, the next generation of precision neuromedicine. By engineering cells that are responsive to external magnetic fields, researchers have started to demonstrate that not only is it theoretically possible to use magnetic fields to affect the behavior of neural circuits, it will likely be a practical technology in the clinical setting in the next few decades. We talk with neuroengineer Dr. Jacob Robinson about the work his lab is doing, the state of the field, and how to escape the generator function that creates technologies that rule us, rather than the other way around.
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#magnetogenetics #mindcontrol #magnets
Dr. Robinson: https://www.robinsonlab.com/
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Check our main channel, @DemystifyingScience for in depth-investigations: https://youtu.be/1OCL5Lq8m6s
PODCAST INFO: Anastasia completed her PhD studying microbial communication at Columbia University. When not talking to brilliant people or making movies, she spends her time painting and exploring the woods. Michael Shilo also did his PhD at Columbia studying the elastic properties of molecular water. When he's not in the film studio, he's exploring sound in music. They are both freelance professors at various universities.
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Dr. Buatois is a geologist at the University of Saskatchewan specializing in trace fossils. He responds to our recent short film exploring the cause of the Great Unconformity - a billion years of missing rock record - which you can watch here: https://youtu.be/PRfND4t-038
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#geology #thegreatunconformity #missingtime
Dr. Buatois: https://ichnoplanet.ca/current-students/lbuatois/
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Check our main channel, @DemystifyingScience for in depth-investigations: https://youtu.be/1OCL5Lq8m6s
PODCAST INFO: Anastasia completed her PhD studying microbial communication at Columbia University. When not talking to brilliant people or making movies, she spends her time painting and exploring the woods. Michael Shilo also did his PhD at Columbia studying the elastic properties of molecular water. When he's not in the film studio, he's exploring sound in music. They are both freelance professors at various universities.
Blog: http://demystifyingscience.com/blog
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We discuss quantum behavior under extreme conditions with MIT Quantum Physicist Dr. Yair Margalit. Topics include the relationship between spin and refractivity, fermi gases and fermi energy, and Paul blocking. Dr. Margalit's relevant pre-print can be found here: https://arxiv.org/pdf/2103.06921.pdf
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Check our main channel, @DemystifyingScience for in depth-investigations: https://youtu.be/1OCL5Lq8m6s
PODCAST INFO: Anastasia completed her PhD studying microbial communication at Columbia University. When not talking to brilliant people or making movies, she spends her time painting and exploring the woods. Michael Shilo also did his PhD at Columbia studying the elastic properties of molecular water. When he's not in the film studio, he's exploring sound in music. They are both freelance professors at various universities.
Blog: http://demystifyingscience.com/blog
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Dr. Michael Levin is a developmental and synthetic biologist best known for two things - the creation of xenobots - biological robots created from frog cells - and his ability to fine-tune the bodyplan of regenerating organisms with morphogenic bioelectric fields. He's speaks with us about the philosophical foundations of his work in regenerative medicine, which include intricate theories of cognition that assert the goal-seeking behavior associated with the "self" is apparent at all scales of life. His work serves as a proof-of-concept for this view of the world, as he has demonstrated it is much more effective to change how organisms grow and regenerate through the careful direction of this goal-seeking behavior, rather than through traditional biochemical methods. His rigorous attention to the philosophy of biology - which includes his forward-thinking definitions of terms like "self," "intelligence," and "cognition" - allows his ideas to jump from the page and into a reality filled with two-headed immortal worms and frog-skin xenobots. See the papers discussed in the podcast down below, and support the podcast by becoming a Patron https://www.patreon.com/demystifysci
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Check our main channel, @DemystifyingScience for in depth-investigations: https://youtu.be/1OCL5Lq8m6s
PODCAST INFO:
Anastasia completed her PhD studying microbial communication at Columbia University. When not talking to brilliant people or making movies, she spends her time painting and exploring the woods. Michael Shilo also did his PhD at Columbia studying the elastic properties of molecular water. When he's not in the film studio, he's exploring sound in music. They are both freelance professors at various universities.
Blog: http://demystifyingscience.com/blog
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MORE READING:
Cognition in Biological Systems: https://www.frontiersin.org/articles/10.3389/fpsyg.2016.00902/full
The Computational Boundary of the Self: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923654/
Living Things Are NOT Machines: https://www.frontiersin.org/articles/10.3389/fevo.2021.650726/full
Life, Death & Self: https://www.sciencedirect.com/science/article/abs/pii/S0006291X20320064
Limb and Organ Regeneration: https://academic.oup.com/ib/article/7/12/1487/5199172
MUSIC: Journey to Consciousness, Daniel Willett
A conversation with Forrest Bishop about the Pleistocene Murders - a whodunnit theory that seeks the cause of the megafaunal extinction that rocked the planet during the most recent period of glaciations - from 2.5 million years ago to about 10,000 years ago. While most theories - including a recent paper from Tel Aviv university point the finger at increasing populations of hungry humans, Forrest proposes that this ignores a crucial, global change that occurred over the course of the Pleistocene: a global decrease in carbon dioxide levels. In the Pleistocene Murders, he proposes that falling carbon dioxide levels led to the dominance of c4 plants - those who can flourish at relatively low partial pressures of CO2. This evolutionary advantage allowed grasslands to dominate the globe... which, in turn, led to a decrease in the caloric content of the trophic foundation of the world's ecosystems. It's an excellent story that binds together geology, chemistry, and biology... and even a little bit of spirit, as humans have an emergent role on the planet that we get to at the very end of the conversation
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Pleistocene Murders Blog: http://www.castaliahouse.com/otherscience-stories-the-pleistocene-murders-part-1/
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Check our main channel, @DemystifyingScience for in depth-investigations:
https://youtu.be/1OCL5Lq8m6s
PODCAST INFO:
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Followup conversation from "The Silence & the Glitch" with Ivor Catt. Today with John Dore, an associate of Mr. Catt during the famed Glitch years of computer pioneering. Please check out part 1 here first: https://youtu.be/47lcjbyqF_k
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Ivor Catt - http://ivorcatt.co.uk http://www.ivorcatt.co.uk/glitch.htm ªº¬˚∆≤≥≤≥
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Today on the show we’ve got a conversation with Dr. Zoe Waller, a researcher at UCL, who specializes in the myriad ways that alternative DNA structures affect biological processes. Today’s guest - and this entire line of investigation concerning alternative structures of DNA - comes to us as a recommendation from one of our patrons, Sean Kettle. Shout out and a big thank you to Sean for connecting us and making today’s conversation possible.
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Zoe Waller Website https://www.ucl.ac.uk/pharmacy/people/dr-zoe-waller
YouTube - DrZoeWaller - https://youtube.com/user/InnocentWal
Twitter - @DrZoeWaller - https://www.twitter.com/DrZoeWaller
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Check our main channel, @DemystifyingScience for in depth-investigations: https://youtu.be/1OCL5Lq8m6s
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MUSIC:
-Humans Win: https://www.lancewconrad.com
This is the second installment of a multipart series with famed electric heretic Ivor Catt. This time, he is here to tell us the story of the Catt question: where does the instantaneous negative charge on the bottom conductor of a simple circuit come from? A satisfying answer to the question would require us to rewire the common conception of how electrical current moves through a circuit, and so has occupied Ivor for decades. the conversation digs into Catt's question, the potential solution of Heaviside energy current, and the stodgy nature of academic science.
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Ivor Catt - http://ivorcatt.co.uk
Maxwell’s original papers on electromagnetism: https://royalsocietypublishing.org/doi/pdf/10.1098/rstl.1865.0008
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Check our main channel, @DemystifyingScience for in depth-investigations: https://youtu.be/1OCL5Lq8m6s
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MUSIC:
-Humans Win: https://www.lancewconrad.com
Today on the show we are speaking with Etienne Fortier Dubois about the problems with scientific publishing and what an ideal future might look like: One where science is freely shared amongst all thinkers, not merely those within a discipline, or those with the institutional power to pay for access. Etienne is presently working on a new journal called the JAWWS - the journal of actually well written science. His goal is to reformat high impact papers so that they can be understood by anyone with a basic undergraduate level comprehension of the material. A fairly low bar in a society like the united states where nearly half of the population has a college degree. Our conversation expands into alternatives to peer review - a recurring point of contention on the show among outsiders and academics alike.
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Étienne Fortier-Dubois - https://etiennefd.com/dgm/the-journal-of-actually-well-written-science
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MUSIC: -Will Van De Crommert
This week’s episode is with Dr. Matthew Herron, professor of Evolutionary Biology at Georgia Tech university. He found us through a series of articles on our blog about the emergence of multicellularity, and joined us for an excellent conversation on the topic. Over the course of the hour we covered all kinds of topics, from what the biology of Volvocine algae can tell us about our own multicelled nature, to more philosophical subjects like the emergence of life on earth, the value of careful speculation, and the way that basic science encourages us to pursue pure curiosity, simply for the sake of knowing what’s possible.
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Matthew Herron - https://www.matthewherron.net https://twitter.com/xprinceps
Support us and Dr. Herron when you purchase his upcoming book: https://amzn.to/3neEkBY
Tong et al, 2021 review or theories of initiation of multicellularity: https://www.preprints.org/manuscript/202111.0194/v1
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MUSIC:
-Michael Vignoia & Shilo Delay
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