The Curbsiders Internal Medicine Podcast

Latest Episodes:

#545: Immune Checkpoint Inhibitor Complications: Recognizing and Managing Immune-Related Adverse Events Nov 09, 2026

Show notes

Recognize immune checkpoint inhibitor (ICI) toxicities. Learn a practical head-to-toe approach to evaluating new symptoms, managing immune-related adverse events (irAEs), and deciding when it’s safe to rechallenge. Dr. Kerry Reynolds, oncologist at Mass General Brigham Cancer Institute and director of the Severe Immunotherapy Complications Service (SIC), joins The Curbsiders to discuss what every internist should know about irAEs.

Claim CME for this episode at https://ce.vcuhealth.org/curbsiders!

Show Segments

Intro
Why internists need to know about ICI toxicities
How checkpoint inhibitors work
Timing of irAEs
Grading the severity of irAEs
Cases:
- Case 1: ICI colitis
- Case 2: ICI hypophysitis
- Case 3: Triple M overlap syndrome: myositis, myocarditis, and myasthenia gravis-like syndrome
Take-home points
Outro

Credits

Written and produced by: Laura Glick MD
Show Notes: Laura Glick MD
Infographic and Cover Art: Zoya Surani
Hosts: Matthew Watto MD, FACP; Nora Taranto MD, MSCE; Laura Glick MD
Reviewer: Sai S Achi MD, MBA, FACP
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Kerry Reynolds MD

Disclosures

Bristol Myers Squibb - Clinical trial support funds received by my institution – started 6/2022, ongoing; SAGA Diagnostics Advisory Board - started 12/2022, ended 12/2022; CME Outfitters– Educational Speaker Fees – started 9/2022, ended 1/2023; Medscape – Educational Speaker Fees - started 1/2023, ended 1/2023; Regeneron – Advisory Board – started 6/25/2024, ended 9/30/2024; Up to Date – started 12/1/2024; Gilead – Advisory Board – started 5/2025.

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Sponsor: FIGS

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Sponsor:Continuing Education Company

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REBOOT #530 Nutrition with Dr. Joan Salge Blake Nov 02, 2026

Show notes

We have another classic episode for you. Confidently counsel on nutrition, as we discuss different dietary patterns and address common patient queries. We are joined by Dr. Joan Salge Blake (Boston University).

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#544: Updated Pulmonary Embolism Guidelines Oct 26, 2026

Show notes

Review the latest 2026 AHA/ACC multisociety pulmonary embolism guidelines with us, including risk stratification, new clinical categories, acute and extended anticoagulation, advanced therapies, follow-ups, and more. We are joined by Drs. Cyrus Askin and Nick Mark from Critical Care Time!

Claim CME for this episode here: https://ce.vcuhealth.org/curbsiders!

Intro
Initial assessment and diagnostic approach to PE
Evolution of PE classification systems
Acute PE treatment
Advanced therapies
Duration of anticoagulation
Post-discharge follow-up
Chronic thromboembolic disease
Outro

Credits

Producer, writer, show notes, infographic, and cover art: Edison Jyang, MD
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Sai S Achi MD,MBA,FACP
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Cyrus Askin, MD; Nick Mark, MD

Disclosures

Dr. Cyrus Askin reports financial disclosures with Astra Zeneca, Speakers Bureau. The Curbsiders report no relevant financial disclosures.

Sponsor: FIGS

Get 15% off your first order at wearfigs.com with the code FIGSRX.

Sponsor: CONTINUING EDUCATION COMPANY

Visit CMEmeeting.org/curbsiders Use promo code Curb30 for 30% off all online courses and webcasts.

Sponsor: Panacea Financial

Visit panaceafinancial.com/curbsiders to talk with a Practice Finance Specialist about what you're planning next.

#543: Navigating Post-Acute Care and Living Options for Older Adults with Dr. Rachel K. Miller Oct 19, 2026

Show notes

Show description:
Learn how to navigate conversations about changing care needs, match older adults with the right site of care, and connect patients and families with resources to make transitions smoother and more successful. We’re joined by Dr. Rachel Miller, to break it all down.

Claim CME for this episode here: https://vcu.cloud-cme.com/course/search?p=4000&curriculum=Podcasts!

Intro
Case
Assessing home environment
Post-hospitalization sites of care
Beyond the hospital: other sites of care
Outro

Credits

Written and Produced by: Ashlee Randolph DO, Rachel K. Miller MD, MSEd, Leah Witt Gaspard, MD
Cover art and infographics by: Ashlee Randolph DO and Rachel K. Miller MD, MSEd
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Rahul Ganatra, MD, MPH
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Dr. Rachel K. Miller, MD, MSEd

Disclosures

Dr. Rachel K. Miller reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures.

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Sponsor: The Permanente Medical Group

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#542: Small Intestinal Bacterial Overgrowth (SIBO) with Dr. Purna Kashyap Oct 12, 2026

Show notes

Expertly evaluate and manage small intestinal bacterial overgrowth (SIBO) with Dr. Purna Kashyap (@KashyapPurna, Mayo profile). Identify when and how to test for SIBO and review treatment options.

Claim CME for this episode here: https://vcu.cloud-cme.com/course/search?p=4000&curriculum=Podcasts!

Intro
Case
Topic
Rapid fire questions/Picks of the Week
Outro

Credits

Written, Produced, Infographic and Cover Art by: Elena Gibson MD
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Leah J. Witt Gaspard, MD
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Purna Kashyap MBBS

Disclosures

Dr. Kashyap is a member of the scientific advisory board of the International Observatory of Biocodex Microbiota Institute, chair of the scientific advisory board of the American Gastroenterology Association Center for Gut Microbiome Education and Research, ad hoc advisory board member for Pendulum, and Intrinsic Medicine, and advisory board member for 32 Biosciences for which he receives equity option as compensation.The Curbsiders report no relevant financial disclosures.

Sponsor: Continuing Education Company

Use promo code Curb30 for 30% off all online courses and webcasts. Visit CMEmeeting.org/curbsiders to learn more.

Sponsor: DeleteMe

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Sponsor: FIGS

Get 15% off your first order at wearfigs.com with the code FIGSRX.

Sponsor: Quince

Download the Quince app for app-exclusive offers, or go to Quince.com. Get free shipping on your order and 365-day returns. Now available in Canada and the UK, too. And when Quince asks where you heard about them, let them know it was Curbsiders.

#541 A Walk Through the 2026 Lipid Management Guidelines Oct 05, 2026

Show notes

Cardiovascular disease caused by hyperlipidemia is the leading cause of death worldwide, but it doesn’t have to be! We have the tools to treat this widespread problem. Dr. Daniel Edmundowicz (Temple University) takes us through how to keep lipids where they should be, low.

Claim CME for this episode at curbsiders.vcuhealth.org!

Show Segments

Intro
Case
Topic
Rapid fire questions/Picks of the Week
Outro

Credits

Written and Produced by: Deborah Gorth MD, PhD
Infographic and Cover Art by: Deborah Gorth MD, PhD and Meryl Gorth RD, MPH
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Emi Okamoto MD
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Daniel Edmundowicz MD, MBA, FACP, FACC

Disclosures

Dr. Edmundwicz reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures.

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Sponsor: Mint Mobile

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Sponsor: Locumstory

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#540 Hotcakes: Varenicline by mail for smoking cessation, anticoagulation for intermediate risk AF, CAC score plus PREVENT, blood testing for CRC, oral PCSK9 inhibitors, and more Sep 28, 2026

Show notes

Join us as we review recent practice-changing articles on Varenicline by mail for smoking cessation, anticoagulation for intermediate risk AF, CAC scores plus PREVENT for ASCVD risk stratification, blood testing for CRC, a new oral PCSK9 inhibitor, and more. Fill your brain hole with a delicious stack of hotcakes! Featuring Paul Williams (@PaulNWilliamz), Rahul Ganatra (@rbganatra), and Matt Watto (@doctorwatto).

Claim CME for this episode at curbsiders.vcuhealth.org!

Written and Hosted by: Rahul Ganatra MD, MPH; Paul Williams, MD, FACP, Matthew Watto MD, FACP
Cover Art: Rahul Ganatra, MD, MPH
Reviewer: Sai S Achi, MD, MBA, FACP
Technical Production: Pod Paste
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

Show Segments

Intro, disclaimer
Varenicline by mail for smoking cessation
Anticoagulation for intermediate-risk AF
CAC scores added to PREVENT for ASCVD
Blood testing for colorectal cancer
Oral PCSK9 inhibitor, negative results for pelacarsan and ziltivekimab
Outro

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Sponsor: The Permanente Medical Group

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Sponsor: UpToDate

Visit www.uptodate.com/cme for CME details. Curbsiders listeners can get 10% off UpToDate packages with code CURB4

Sponsor: Panacea Legal

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REBOOT #511 Alzheimer's Disease: Updates in Diagnosis and Treatment Sep 21, 2026

Show notes

Blood-based Biomarkers, Anti-Amyloid Therapies and Beyond

We have another classic episode for you. From blood-based biomarkers to anti-amyloid treatments, join us as we explore the latest in Alzheimer’s disease diagnosis and treatment with Dr. Halima Amjad. This episode will equip you to guide your patients about the latest Alzheimer’s diagnostics as well as eligibility, risks and monitoring for anti-amyloid therapies.

Claim CME for this episode at curbsiders.vcuhealth.org!

Intro
Case
Cognitive and functional history reminders
Diagnosing Alzheimer’s Disease
Blood-based biomarkers
Anti-amyloid therapy indications, eligibility and contraindications
Patient counseling and treatment decisions
ARIA
Key takeaways
Outro

Credits

Written and Produced by: Natalie Barrett DO, Rachel K Miller MD
Show notes, cover art and infographic: Natalie Barrett DO, Rachel K Miller MD, Leah Witt MD
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Sai S Achi MD, MBA,FACP
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Halima Amjad, MD

Disclosures

Dr. Amjad reports financial relationships with Centene (Advisor) and Craniometrix (Advisor). Relationships have not ended. The Curbsiders report no relevant financial disclosures.

The production of this episode was supported by the Penn Geriatrics AGE-SMART Geriatric Workforce Enhancement Grant. This podcast content is solely the responsibility of the authors and does not necessarily represent the official views of the Health Resources and Services Administration or the U.S. Department of Health and Human Services.

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#539 TikTok Trends in Medicine Sep 14, 2026

Show notes

Peptides, Mouth Tape, Raw Milk & More: What’s Worth the Hype?

Learn the evidence on social media wellness trends and how to discuss with your patients (and friends!) without being dismissive (or falling for the hype). Explore viral trends like peptides, red light masks, sleepy girl mocktails and mouth taping along with understanding influencer incentives for promoting wellness trends. We’re joined by infectious disease epidemiologist and science communicator Jessica Malaty Rivera to talk evidence, uncertainty, misinformation, and trust, @jessicamalatyrivera, (JPHMP, @jessicamalatyrivera, Making Science Make Sense Substack),

Claim CME for this episode at curbsiders.vcuhealth.org!

Intro
Case
Why health information spreads on social media
Talking to patients about viral wellness trends
Peptides
Red light masks
Mouth taping
Sleepy girl mocktails
Raw milk and the appeal-to-nature fallacy
Fibermaxxing
Contrast therapy and cold plunging
Take-home points
Outro

Credits

Producers, Writers, Show Notes, Infographics, Cover Art:: Rand Mudafr, Leah Witt Gaspard, MD
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Sai Achi, MD MBA FACP
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Jessica Malaty Rivera

Disclosures

Jessica Malaty Rivera reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures.

Sponsor: Continuing Education Company

For Curbsiders listeners, there’s also an exclusive offer: use promo code Curb30 for 30% off all online courses and webcasts. Visit CMEmeeting.org/curbsiders to learn more.

Sponsor: Quince

Download the Quince app for app-exclusive offers, or go to Quince.com/curb. Get free shipping on your order and 365-day returns. Now available in Canada and the UK, too.

Sponsor: UpToDate

For a limited time, Curbsiders listeners can get 10% off UpToDate packages with code CURB3 . Visit store.uptodate.com

Sponsor: Gusto

Try Gusto today at gusto.com/CURB, and get three months free when you run your first payroll.

REBOOT #505 Demystifying Dizziness with Dr. David Hale Sep 07, 2026

Show notes

We have another classic episode for you. Dizziness can be a daunting presenting symptom. Demystify dizziness with us by breaking it down by timing and triggers, various pertinent physical maneuvers, and even an approach to chronic dizziness. We are joined by our esteemed guest Dr. David Hale (Johns Hopkins)!

Sponsor: Babbel

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Sponsor: Locumstory

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Sponsor: Quince

Go to Quince.com/curb for free shipping on your order and 365-day returns. Now available in Canada and the UK, too

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