The Curbsiders Internal Medicine Podcast

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#511 Alzheimer's Disease: Updates in Diagnosis and Treatment Jan 12, 2026

Show notes

Blood-based Biomarkers, Anti-Amyloid Therapies and Beyond

From blood-based biomarkers to anti-amyloid treatments, join us as we explore the latest in Alzheimer’s disease diagnosis and treatment with Dr. Halima Amjad. This episode will equip you to guide your patients about the latest Alzheimer’s diagnostics as well as eligibility, risks and monitoring for anti-amyloid therapies.

Intro
Case
Cognitive and functional history reminders
Diagnosing Alzheimer’s Disease
Blood-based biomarkers
Anti-amyloid therapy indications, eligibility and contraindications
Patient counseling and treatment decisions
ARIA
Key takeaways
Outro

Credits

Written and Produced by: Natalie Barrett DO, Rachel K Miller MD
Show notes, cover art and infographic: Natalie Barrett DO, Rachel K Miller MD, Leah Witt MD
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Sai S Achi MD, MBA,FACP
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Halima Amjad, MD

Disclosures

Dr. Amjad reports financial relationships with Centene (Advisor) and Craniometrix (Advisor). Relationships have not ended. The Curbsiders report no relevant financial disclosures.

The production of this episode was supported by the Penn Geriatrics AGE-SMART Geriatric Workforce Enhancement Grant. This podcast content is solely the responsibility of the authors and does not necessarily represent the official views of the Health Resources and Services Administration or the U.S. Department of Health and Human Services.

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#510 Diverticulitis for the Hospitalist Jan 05, 2026

Show notes

Diverticulitis Simplified: Imaging, Antibiotics, Diet, and When to Call Surgery
Master diverticulitis! Learn how to distinguish uncomplicated from complicated disease, when to reach for antibiotics, and which patients need surgical consultation. We’re joined by Dr. Bob Hollis (University of Alabama at Birmingham) and Dr. Andrew Webster (Emory University).
Claim free CME for this episode at curbsiders.vcuhealth.org!
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Show Segments

Intro
Rapid Fire Questions
Picks of the Week
Case 1
Defining and Classifying Diverticulosis vs Diverticulitis
History and Physical Exam
Labs and Imaging
Disposition: Admit or Discharge?
Antibiotics: Who Needs them and How to Choose
Duration of Antibiotic Therapy
Diagnostic Pitfalls and Redflags
Nutrition in the Hospitalized Patient with Diverticulitis
Case 2
Surgery and IR Consultation
Antibiotics in Diverticular Abscess
Repeat Imaging in Undrainable Abscess
Elective Surgery in Diverticulitis
Case 3
Diverticulitis with Perforation
Counseling Patients Undergoing Surgery
Ostomy Reversal Timing

Credits

Writer, Producer, and Show Notes: Reaford Blackburn, Jr., MD
Infographic and Cover Art: Caroline Coleman, MD
Hosts: Monee Amin, MD and Meredith Trubitt, MD
Reviewer: Rahul Ganatra
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guests: Bob Hollis, MD and Andrew Webster, MD

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UNLOCKED PATREON #60 Anticoagulation DVT/PE Dec 29, 2025

Show notes

Matt and Paul recap top pearls from a recent episode on Anticoagulation for Venous Thromboembolism with Dr. Tara Lech, PharmD. They also answer listener questions and share their picks of the week.
Picks of the week:
Paul Recommends: Death Stranding 2: On the Beach (videogame)
Matt Recommends: CJ Box novels about Joe Picket

#509 Fresh Hypertension Guidelines. West Philadelphia Doc Jordy Cohen Keeps Our Hypertension Management Fresh Dec 22, 2025

Show notes

Intro
Case: Jeremy
Wearable devices inaccuracies
Ideal blood pressure measurement
Diagnosis and workup
Management and fixed-dose combination pills
Case: Jolene and pregnancy
Outro

Credits

Written and Produced by: Deborah Gorth MD, PhD
Infographic and Cover Art by: Deborah Gorth MD, PhD and Meryl Gorth RD, MPH
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Emi Okamoto MD
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Jordana Cohen MD, MSCE

Disclosures

Financial Relationships disclosed for Dr. Jordana Cohen: Wolters Kluwer (Royalties or Patent Beneficiary) and National Institutes of Health (Grant or research support)

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#508: ASCVD Risk & Lipids Update! PREVENT, ApoB, Lp(a) + Next-Gen Therapies Dec 15, 2025

Show notes

Master cardiovascular disease prevention! Learn how to apply the new PREVENT risk calculator, use the CPR framework for risk reclassification, and interpret ApoB and Lp(a) in modern lipid management. We’re joined by Dr. Laurence Sperling to break down what’s new in ASCVD risk assessment and prevention.
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Show Segments

Intro
Case 1 from Kashlak
Risk assessment framework
ApoB and Non-HDL cholesterol
Lipoprotein(a) and its importance
The PREVENT risk score and its implications
Statins and other lipid lowering therapies
The role of diet and lifestyle in lipid management
Case 2 from Kashlak
Familial Hypercholesterolemia diagnosis and management
Key takeaways
Outro

Credits

Producer, Writer, Shownotes, Infographic, and Cover art: Ben Furman, MPH
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Leah Witt, MD
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Laurence Sperling, MD

Disclosures

Dr. Sperling reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures.

Sponsor: Bucksbaum-Siegler Institute

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#507 Swinging the Pendulum on Menopause Care With Dr Rachel Rubin Dec 08, 2025

Show notes

Transform your approach to menopause care with the latest evidence and expert insights you can use tomorrow. Learn how to move beyond outdated WHI-era fears and confidently prescribe individualized, effective hormonal therapies. We’re joined by urologist and sexual medicine specialist Dr Rachel Rubin (@DrRachelRubin), who brings clarity, practicality, and a fresh perspective to this rapidly evolving field.
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Show Segments

Intro
Case
Shifting care for menopause
WHI/black box warning labels
What makes you nervous?
Local vaginal treatments
Progesterone therapy
Estrogen therapy
Testosterone therapy
Perimenopause
Outro

Credits

Producer, Writer, Show Notes, Infographic, Cover Art: Molly Heublein MD
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP; Molly Heublein MD
Reviewer: Leah Witt MD
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Rachel Rubin MD

Disclosures

Dr. Rachel Rubin reports financial support from Sprout Pharmaceuticals . The Curbsiders report no relevant financial disclosures.
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Sponsor: Bucksbaum-Siegler Institute

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#506 DIGEST-Hotcakes: PSA Screening, Acetaminophen and Autism, COVID19 Vaccines and Cancer, Aspirin and Anticoagulation in Coronary Artery Disease Dec 01, 2025

Show notes

Join us as we review recent articles and news featured in The DIGEST #70, including PSA screening, acetaminophen and autism, COVID19 vaccines and cancer, and aspirin and anticoagulation in coronary artery disease. Fill your brain hole with a delicious stack of hotcakes! Featuring Drs. Paul Williams (@PaulNWilliamz), Nora Taranto (@norataranto), Rahul Ganatra (@rbganatra), Laura Glick (@lauraglick) and Matt Watto (@doctorwatto).
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Credits

Written and Hosted by: Nora Taranto MD; Rahul Ganatra MD MPH, Laura Glick MD, Paul Williams, MD, FACP, Adam Cifu MD, Matthew Watto MD, FACP
Cover Art: Rahul Ganatra, MD MPH
Reviewers: Rahul Ganatra MD MPH; Paul Williams, MD, FACP, Matthew Watto MD, FACP; Sai S Achi MD, MBA, FACP
Technical Production: Pod Paste
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

Show Segments

Intro, disclaimer
Prostate Cancer Screening
Acetaminophen and Autism
COVID19 vaccines and cancer risk
Aspirin and anticoagulation in coronary artery disease
Outro

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REBOOT: #466 Cirrhosis Update with Scott Matherly Nov 24, 2025

Show notes

Intro, disclaimer, guest bio
Case from Kashlak; Definitions
Cirrhosis Diagnosis and Initial Evaluation
Cirrhosis Physical Examination
Decompensated Cirrhosis Management
Ascites and TIPS
MELD and transplant consideration
Outro

Credits

Written and Produced by: Elena Gibson MD
Infographic and Cover Art: Edison Jyang MD
Hosts: Paul Williams MD, FACP; Elena Gibson MD
Reviewer: Emi Okamoto MD
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Scott Matherly MD

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#505 Demystifying Dizziness with Dr. David Hale Nov 17, 2025

Show notes

Dizziness can be a daunting presenting symptom. Demystify dizziness with us by breaking it down by timing and triggers, various pertinent physical maneuvers, and even an approach to chronic dizziness. We are joined by our esteemed guest Dr. David Hale (Johns Hopkins)!
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Show Segments

Intro
Case 1
Defining dizziness and vertigo
Timing and triggers
Episodic dizziness/vertigo
Dix-hallpike and Epley maneuver
Case 2
Acute vestibular syndrome and the HINTS+ exam
Case 3
Chronic dizziness
Persistent postural-perceptual dizziness
Takeaways and outro

Credits

Writer, Producer, Shows Notes, Infographic/Cover Art: Edison Jyang, MD
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Sai S Achi MD, MBA, FACP
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: David Hale, MD

Disclosures

Dr. Hale reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures.

Sponsor: DoxGPT by Doximity

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Sponsor: Freed

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#504: Adult Eating Disorders in the GLP-1 Era Nov 10, 2025

Show notes

Explore how GLP-1 meds can help or harm eating disorders with Dr. Laura Bridge
When weight-loss meds meet eating disorders: GLP-1 drugs are reshaping medicine, but could they also be fueling disordered eating? Join Dr. Laura Bridge as we unpack the risks, red flags, and how to keep “healthy” from turning harmful. Also, how to approach restrictive eating disorders, bulimia, and binge eating disorder as a PCP.
Claim CME for this episode at curbsiders.vcuhealth.org!
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Show Segments

Introduction
Defining Eating Disorders
Screening & Permission to Discuss
Clinical Approach & History Gathering
Treatment Framework
GLP-1 Contraindications
Dr. Bridge’s Take-Home Points

Credits

Producer, writer, show notes, cover art and infographics: Isabel Valdez, PA-C
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Molly Heublein MD
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Laura Bridge MD, FACP

Disclosures
Dr. Laura Bridge no relevant financial disclosures. The Curbsiders report no relevant financial disclosures.
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