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    Science

    Straight Talk MD

    I’m a skeptic searching for the truth in all matters related to science and medicine, especially where it intersects with economics, politics, and public health. The truth is out there and we’re going to find it together…

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    Latest Episodes:
    COVID Commentaries. Episode 1: Ill Prepared Apr 20, 2020
    Show notes

    The worldwide spread of COVID-19 is being called the "pandemic of the century" by some. Others are watching the debacle unfold can only wonder if the response to the COVID-19 pandemic will someday be called "the fiasco of the century." The 24/7 news channels have created worldwide mass hysteria by reporting events from a sensationalist point of view without giving appropriate context. Civilians are terrified. The economy has been damaged for a generation. These commentaries share observations, analysis, experiences, and perspectives from a narrator who is both an observer and a participant on the front lines of healthcare. Episode 1: Ill Prepared…


    "Ethics in COVID-19 World" with Arthur Caplan and Greg Pence Apr 08, 2020
    Show notes

    In Wuhan China and later Italy, the healthcare system was rapidly overrun with critically ill patients and insufficient resources to save them all. When the population's health needs vastly exceeded the system's capacity, "utilitarian ethics" quickly replaced normal medical ethics; disaster standards of care replaced normal standards of care. Ventilators and drugs in short supply were allocated only to those patients most likely to survive; family members were not allowed to visit dying relatives in the hospital, and CPR was suspended for COVID-19 patients. Entire countries have been shut down with catastrophic economic consequences to tens of millions of people in an attempt to contain the virus. In each case, the health of the community trumped the needs of the individual. Bioethicists Arthur Caplan and Gregory Pence discuss the complex ethical issues we face in a COVID-19 world.


    Coronavirus Update #5 [March 31, 2020] with Dr. Paul Offit Apr 02, 2020
    Show notes

    Dr. Paul Offit is a virologist and infectious disease specialist from Children's Hospital of Philadelphia. We discuss the COVID surge in NY, immunity testing, the coming surge in California, the safest/best timing to lift the national quarantine, and much more.


    Coronavirus Update #4 [March 25, 2020] with Dr. Paul Offit Mar 24, 2020
    Show notes

    As we enter the logarithmic phase of the U.S. COVID-19 epidemic, the Coronavirus Pandemic just got very real. Today we discuss the Federal government's preparedness for this pandemic, protective gear shortages for healthcare workers on the front lines [especially N-95 masks], chloroquin, Remdesivir update, ongoing failures of testing, and much, much more. Today, Dr. Paul Offit assesses the arc we're on and so far, it isn't good. Definitely worth a listen.


    Coronavirus Update #3 [March 18, 2020] with Dr. Paul Offit Mar 18, 2020
    Show notes

    The worldwide coronavirus pandemic of fear is escalating rapidly. In an attempt to avoid the spread of COVID-19 and a public health disaster "like no other," life as we know it in the U.S. has come to a grinding halt.

    Today, world renowned virologist and infectious disease specialist, Paul Offit, talks about the draconian measures being taken in the U.S. to avoid repeating the Italian experience with COVID-19. He opines on the risks of expediting a COVID-19 vaccine, the tepid promise of antivirals (Remdesivir), sane measures to minimize exposure, the likely impact of widespread COVID-19 testing in the U.S., and much, much more. Definitely worth a listen.


    Coronavirus Update #2 [March 10, 2020] with Dr. Paul Offit Mar 10, 2020
    Show notes

    A lot has happened in the world since last week! In today's show, Paul separates fact from fiction on what we know about COVID-19 infections. He opines on the extreme [and often irrational] measures being taken worldwide to try and contain the coronavirus epidemic. Finally, he makes some cautious predictions about what to expect in the coming weeks. One thing is clear: the pandemic of fear surrounding the coronavirus is causing far more damage worldwide than the virus. It's definitely worth a listen.


    Coronavirus Update #1 [March 2, 2020] with Dr. Paul Offit Mar 02, 2020
    Show notes

    When I contacted Dr. Paul Offit last Thursday for an interview on the coronavirus, he was literally at the CDC getting the latest update on what's happening with COVID-19. In today's show, Paul separates fact from fiction on the coronavirus and makes some cautious predictions about what to expect in the coming weeks. It's definitely worth a listen.


    On Pins and Needles Feb 17, 2020
    Show notes

    The most cynical surgeons like to say that anesthesiology is ninety-nine percent boredom and one-percent sheer terror. Strange Daze is about the one percent.

    The "one percent" can occur with any type of anesthesia, not just general anesthesia, which brings us to today's episode: "On Pins and Needles."

    Spinal anesthesia is still a popular alternative to general technique for certain types of surgery, but every anesthetic technique has its limitations, including spinal anesthesia.

    In today's episode, our narrator learns the limitations of spinal anesthesia in his first year of anesthesia residency when assigned to the orthopedic "total joint" room.

    In the hands of a master, spinal anesthesia is a beautiful and elegant alternative to general anesthesia. In the hands of an inexperienced anesthesia resident, spinal anesthesia can suddenly and unexpectedly devolve into the "one percent".

    You may be wondering how spinal anesthesia can go so wrong. Truth be told, in about a million and a half different ways… Tune in and you'll find out how…


    7 Stories of Science Gone Wrong with Paul Offit MD Oct 28, 2019
    Show notes

    I have Dr. Paul Offit in the virtual studio to discuss seven stories of science gone wrong. The seven discoveries were initially promoted as "stunning scientific breakthroughs" but each one turned out to have a dark side that was harmful to the human race. Some of these "stunning breakthroughs" still threaten the future of our species today.

    In the final part of the interview, I ask Paul to comment on some of today's high-profile health controversies: e-cigarettes, Bisphenol-A, PSA screening for prostate cancer, mammograms, and Genetically Modified Food, and question if perhaps we're repeating this same "science-gone-wrong" history. Paul presents some practical advice on how we can avoid repeating these same kinds of mistakes as we tackle our top challenges in science and medicine today.


    The Xanax Epidemic with Anna Lembke M.D. Oct 07, 2019
    Show notes

    Today we discuss the latest physician-fueled prescription pill epidemic. This time it's Xanax and benzodiazepines, the class of drugs called "benzos." As Yogi Berra once said, "It's déjà vu all over again."

    Whether it's Xanax, Ativan, Restoril, Klonapin, or Valium, the bad news is that millions of people have become addicted to benzos through inappropriate physician prescriptions. Tens of thousands more have overdosed on benzos.

    Tune in to my interview with Dr. Anna Lembke, Chief of the Stanford Addiction Medicine Dual Diagnosis Clinic, and bestselling author of the expose on the prescription opioid epidemic, "Drug Dealer MD." We discuss the other prescription drug problem and what we can do about it.


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