Saving Lives Podcast: Critical Care w/eddyjoemd

Latest Episodes:

The Data on Natural Immunity and Mandates Jan 27, 2022

Show notes

Are the vaccine mandates that are seen around the world today evidence based? Based on these data, it appears that they are not.

Show Notes: https://eddyjoemd.com/vaccine-mandate/

Although great care has been taken to ensure that the information in this podcast are accurate, eddyjoe, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.

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The Heart and COVID-19 Are Not BFF's Jan 24, 2022

Show notes

Reviewing a recently published article on Cardiac Injury in COVID-19 that was published in the Intensive Care Medicine Journal by Julie Helms, Alain Combes and Nadia Aissaoui.

Show Notes: https://eddyjoemd.com/foamed

Citation: Helms J, Combes A, Aissaoui N. Cardiac injury in COVID-19. Intensive Care Med. 2022 Jan;48(1):111-113. doi: 10.1007/s00134-021-06555-3. Epub 2021 Nov 2. PMID: 34727214; PMCID: PMC8562019.

How to Stay Up To Date with the Critical Care Literature Jan 22, 2022

Show notes

Many people often ask me how I stay up to date with the most recent literature in Critical Care Medicine. This podcast will hopefully explain this.

Show Notes: https://eddyjoemd.com/up-to-date-critical-care/

Plasma-lyte vs. Saline (0.9% NaCl) in the Critical Ill: Reviewing the PLUS Trial Jan 19, 2022

Show notes

The PLUS Trial compared plasma-lyte to 0.9% NaCl (aka normal saline) in patients who were critically ill and needed IV fluids. In this episode, we review the PLUS trial that compared Plasma-lyte to Saline (0.9% NaCl) in critically ill patients. We discuss the rationale behind the trial, its design, and the key findings. We also delve into the implications of the study results and explore how this evidence could impact clinical practice. Additionally, we touch on the broader debate surrounding the use of crystalloid solutions in critical care and discuss the limitations of the study. Whether you are a clinician or a student, this episode will provide you with a deeper understanding of the current evidence-based practices regarding the use of fluids in critically ill patients.

Show Notes: https://eddyjoemd.com/plus-trial/

Citation: Finfer S, Micallef S, Hammond N, Navarra L, Bellomo R, Billot L, Delaney A, Gallagher M, Gattas D, Li Q, Mackle D, Mysore J, Saxena M, Taylor C, Young P, Myburgh J; PLUS Study Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults. N Engl J Med. 2022 Jan 18. doi: 10.1056/NEJMoa2114464. Epub ahead of print. PMID: 35041780.

Vasopressin & Methylprednisolone: Time to Add Them to ACLS Protocols? Jan 18, 2022

Show notes

A new study is showing that we should add vasopressin and methylprednisolone to our ACLS protocols as it helps patients achieve ROSC faster. Should they be standard of care? In this episode, we discuss the use of vasopressin and methylprednisolone in cardiac arrest and their potential benefits. We explore the studies that have examined the use of these medications in ACLS protocols and their mechanisms of action. We also review the controversies surrounding their use, including the lack of strong evidence and potential adverse effects. Join us as we weigh the pros and cons of incorporating these drugs into our resuscitation strategies.

Show Notes: https://eddyjoemd.com/vasopressin-methylprednisolone/

Citations:
Andersen LW, Isbye D, Kjærgaard J, Kristensen CM, Darling S, Zwisler ST, Fisker S, Schmidt JC, Kirkegaard H, Grejs AM, Rossau JRG, Larsen JM, Rasmussen BS, Riddersholm S, Iversen K, Schultz M, Nielsen JL, Løfgren B, Lauridsen KG, Sølling C, Pælestik K, Kjærgaard AG, Due-Rasmussen D, Folke F, Charlot MG, Jepsen RMHG, Wiberg S, Donnino M, Kurth T, Høybye M, Sindberg B, Holmberg MJ, Granfeldt A. Effect of Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest: A Randomized Clinical Trial. JAMA. 2021 Oct 26;326(16):1586-1594. doi: 10.1001/jama.2021.16628. PMID: 34587236; PMCID: PMC8482303.

Haukoos J, Douglas IS, Sasson C. Vasopressin and Steroids as Adjunctive Treatment for In-Hospital Cardiac Arrest. JAMA. 2021 Oct 26;326(16):1583-1585. doi: 10.1001/jama.2021.15460. Erratum in: JAMA. 2021 Nov 9;326(18):1874. PMID: 34587235.

Holmberg MJ, Granfeldt A, Mentzelopoulos SD, Andersen LW. Vasopressin and glucocorticoids for in-hospital cardiac arrest: A systematic review and meta-analysis of individual participant data. Resuscitation. 2022 Jan 3;171:48-56. doi: 10.1016/j.resuscitation.2021.12.030. Epub ahead of print. PMID: 34990764.

Atorvastatin for ICU COVID Patients: Not Ready for Prime Time (Journal Club-ish) Jan 16, 2022

Show notes

Could atorvastatin (lipitor) help improve outcomes in our COVID patients who are in the ICU? Let's review the evidence from this trial.

Show Notes: https://eddyjoemd.com/atorvastatin-covid/

Citation: MJ. 2022 Jan 7;376:e068407. doi: 10.1136/bmj-2021-068407. PMID: 34996756.

Changing ECMO Criteria: Do Days on Vent Prior to Cannulation Matter? Jan 14, 2022

Show notes

Traditionally, we do not cannulate patients for VV-ECMO if they've been on invasive mechanical ventilation for more than 7 days. These new data say we should allow for a bit more grace.

Show Notes: https://eddyjoemd.com/ecmo/

Citation: Hermann M, Laxar D, Krall C, Hafner C, Herzog O, Kimberger O, Koenig S, Kraft F, Maleczek M, Markstaller K, Robak O, Rössler B, Schaden E, Schellongowski P, Schneeweiss-Gleixner M, Staudinger T, Ullrich R, Wiegele M, Willschke H, Zauner C, Hermann A. Duration of invasive mechanical ventilation prior to extracorporeal membrane oxygenation is not associated with survival in acute respiratory distress syndrome caused by coronavirus disease 2019. Ann Intensive Care. 2022 Jan 13;12(1):6. doi: 10.1186/s13613-022-00980-3. PMID: 35024972; PMCID: PMC8755897.

2022 Resolutions: A Fresh-ish Start Jan 07, 2022

Show notes

The following are my resolutions for the year 2022 with regards to my educational and social media endeavors to bring you all the best.

Show Notes: https://eddyjoemd.com/2022-resolutions/

Obesity in Critical Illness & COVID-19: A Very Bad Combination Dec 08, 2021

Show notes

Obesity is a risk factor for COVID that we are not hearing enough about. It is a modifiable risk factor that should be addressed.

Show Notes: https://eddyjoemd.com/obesity-covid/

Anderson MR, Shashaty MGS. Impact of Obesity in Critical Illness. Chest. 2021 Aug 5;160(6):2135–45. doi: 10.1016/j.chest.2021.08.001. Epub ahead of print. PMID: 34364868; PMCID: PMC8340548.

Bicarbonate for Respiratory Acidosis: Not So Fast Dec 05, 2021

Show notes

When a patient has an acidosis which is respiratory in nature, the right answer should not include using sodium bicarbonate. In this podcast episode, we explore the use of bicarbonate for the treatment of respiratory acidosis. While it is a commonly used therapy, recent studies have suggested that it may not be as effective as previously thought. We discuss the physiology of respiratory acidosis, the rationale for using bicarbonate, and the potential drawbacks and complications associated with its use. We also review the latest evidence and guidelines regarding bicarbonate therapy and offer practical tips for clinicians when managing patients with respiratory acidosis. Tune in to learn more about this important topic and how to optimize your treatment approach.

Show Notes: https://eddyjoemd.com/bicarbonate-respiratory-acidosis/

Website: www.eddyjoemd.com Instagram: www.instagram.com/eddyjoemd Twitter: www.twitter.com/eddyjoemd Facebook: www.facebook.com/eddyjoemd Podcast: https://anchor.fm/eddyjoemd My Amazon store for resources you may find helpful: www.amazon.com/shop/eddyjoemd

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