Research To Practice | Oncology Videos

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**Research To Practice | Oncology Videos**

Featuring the video recorded proceedings of events held in conjunction with important scientific symposia, live webcasts and closed meetings featuring the perspectives of renowned clinical investigators, these videos provide an overview of important advances in the management of a number of solid tumors and hematologic cancers.

Latest Episodes:

Multiple Myeloma | Breakfast with the Investigators: Multiple Myeloma Jul 11, 2022

Show notes

Featuring perspectives from Drs Ajai Chari, Elizabeth O'Donnell and Robert Orlowski, including the following topics:

Introduction (0:00)
Front-Line and Maintenance Treatment Options for Patients with Multiple Myeloma (MM) (2:03)
Selection and Sequencing of Therapy for Patients with Relapsed/Refractory MM (28:22)
Future Directions in the Management of MM (36:31)

CME information and select publications

Gastroesophageal Cancers | Meet The Professor: Optimizing the Management of Gastroesophageal Cancers — Part 3 Jul 08, 2022

Show notes

Featuring perspectives from Prof Eric Van Cutsem, including the following topics:

Introduction: Journal Club with Prof Van Cutsem (0:00)
Case: A woman in her mid 70s with HER2-negative metastatic gastric cancer (MSI high, PD-L1 >20%) — Nemrata I Peswani, MD (16:51)
Case: A man in his mid 70s with multiple comorbidities and HER2-negative metastatic gastroesophageal junction (GEJ) adenocarcinoma (MSS, PD-L1-positive) — Shaachi Gupta, MD, MPD (23:03)
Case: A man in his mid 50s with HER2-positive metastatic GEJ adenocarcinoma (PD-L1 low) — Vignesh Narayanan (27:13)
Case: A woman in her mid 60s with HER2-equivocal metastatic GEJ adenocarcinoma — Lionel A Kankeu Fonkuoa, MD (30:53)
Case: A woman in her mid 60s with HER2-negative metastatic esophageal adenocarcinoma with COPD and vascular disease (pMMR, PD-L1 CPS 5) — Philip L Brooks, MD (46:57)
Case: A man in his mid 60s with HER2-negative localized esophageal adenocarcinoma and history of GERD and Barrett's esophagus (pMMR, PD-L1 CPS 1) — Matthew R Strickland, MD (53:18)
Case: A man in his early 60s with squamous cell carcinoma of the esophagus who has local and oligometastatic nodal recurrence — Erik Rupard, MD (57:25)

CME information and select publications

Breast Cancer | Oncology Today with Dr Neil Love: Recent Updates in HER2-Low Breast Cancer (Companion Faculty Lecture) Jul 07, 2022

Show notes

Featuring a slide presentation and related discussion from Dr Adam Brufsky, including the following topics:

Targeted therapies for HER2-expressing breast cancer (0:00)
Rationale for targeting HER2-low breast cancer (6:51)
Recent data with T-DXd in advanced HER2-low breast cancer (12:57)

CME information and select publications

Breast Cancer | Oncology Today with Dr Neil Love: Recent Updates in HER2-Low Breast Cancer Jul 07, 2022

Show notes

Featuring an interview with Dr Adam Brufsky, including the following topics:

Trastuzumab deruxtecan (T-DXd) for HER2-low breast cancer; recently presented findings from the DESTINY-BREAST04 trial (0:00)
Impact of heterogeneous disease on the detection of HER2-low expression in patients with breast cancer (7:48)
Case: A woman with low-volume, asymptomatic and nonvisceral ER-positive, HER2-low breast cancer (13:16)
Case: A woman with high-volume, symptomatic and visceral HER2-low breast cancer; treating ER-negative, HER2-low disease (18:44)
Toxicities associated with T-DXd (25:25)
Ongoing trials evaluating T-DXd in earlier lines of therapy (31:28)

CME information and select publications

Lung Cancer | Proceedings from a CME Hybrid Symposium Series Held in Conjunction with the 2022 ASCO Annual Meeting Jul 06, 2022

Show notes

Featuring perspectives from Drs Justin Gainor, Corey Langer, Luis Paz‑Ares, Heather Wakelee, Jared Weiss and Helena Yu, including the following topics:

Introduction (0:00)
Incorporation of immunotherapeutic strategies into the management of nonmetastatic non-small cell lung cancer (NSCLC) — Heather Wakelee, MD (3:18)
Contemporary treatment for localized and metastatic NSCLC with EGFR mutations — Helena Yu, MD (33:46)
Research advances shaping the current and future treatment of metastatic NSCLC with ALK rearrangements, ROS1 rearrangements or RET fusions — Justin F Gainor, MD (58:03)
Targeting alterations in MET, HER2, KRAS and other oncogenes in NSCLC — Jared Weiss, MD (1:19:24)
Current and future management of metastatic NSCLC without a targetable tumor mutation — Corey J Langer, MD (1:42:57)
Current treatment paradigm for small cell lung cancer — Luis Paz-Ares, MD, PhD (2:07:58)

CME information and select publications

Hematologic Oncology | Oncology Today with Dr Neil Love: Current and Future Management of Follicular Lymphoma (Companion Video Lecture) Jul 05, 2022

Show notes

Featuring a slide presentation and related discussion from Dr Loretta Nastoupil, including the following topics:

Current and emerging therapies for patients with follicular lymphoma (FL) (0:00)
CAR (chimeric antigen receptor) T-cell therapy for patients with FL (10:34)
Efficacy and tolerability of bispecific antibodies for patients with FL (19:6)

CME information and select publications

Hematologic Oncology | Oncology Today with Dr Neil Love: Current and Future Management of Follicular Lymphoma Jul 05, 2022

Show notes

Featuring an interview with Dr Loretta Nastoupil, including the following topics:

Impact of COVID-19 on the management of follicular lymphoma (FL) (0:00)
Case: A woman in her late 50s with Grade IIIA symptomatic FL (3:48)
Case: A man in his early 70s with low-grade FL and asymptomatic adenopathy 6 years after a complete response (8:21)
Case: A patient with heavily pretreated relapsed/refractory FL who received copanlisib followed by CAR (chimeric antigen receptor) T-cell therapy (14:56)
Case: A woman in her early 50s with refractory FL who received mosunetuzumab (18:06)
Novel treatment strategies for FL and considerations for the future (23:28)

CME information and select publications

Urothelial Bladder Cancer | Proceedings from a CME Hybrid Symposium Series Held in Conjunction with the 2022 ASCO Annual Meeting Jun 30, 2022

Show notes

Featuring perspectives from Drs Yohann Loriot, Elizabeth Plimack and Jonathan Rosenberg, including the following topics:

Introduction (0:00)
Current and Future Management of Localized Urothelial Bladder Cancer (UBC) (2:59)
First-Line Treatment for Patients with Metastatic UBC (mUBC) (28:29)
Later-Line Therapeutic Options for Patients with mUBC: Novel Investigational Strategies (47:08)

CME information and select publications

Chronic Lymphocytic Leukemia and Non-Hodgkin Lymphoma| Proceedings from a CME Hybrid Symposium Series Held in Conjunction with the 2022 ASCO Annual Meeting Jun 29, 2022

Show notes

Featuring perspectives from Drs Ian Flinn, Brian Hill, John Leonard, Matthew Lunning, Laurie Sehn and Mitchell Smith, including the following topics:

Introduction (0:00)
Newly Diagnosed Chronic Lymphocytic Leukemia (CLL) — Ian W Flinn, MD, PhD (3:07)
Relapsed/Refractory CLL; Novel Investigational Strategies — Mitchell R Smith, MD, PhD (32:31)
Treatment for Follicular Lymphoma — John P Leonard, MD (57:24)
Management of Mantle Cell Lymphoma — Matthew Lunning, DO (1:21:22)
Caring for Patients with Diffuse Large B-Cell Lymphoma — Laurie H Sehn, MD, MPH (1:44:40)
Chimeric Antigen Receptor T-Cell Therapy — Brian T Hill, MD, PhD (2:10:26)

CME information and select publications

Breast Cancer | Proceedings from a CME Hybrid Symposium Series Held in Conjunction with the 2022 ASCO Annual Meeting Jun 28, 2022

Show notes

Featuring perspectives from Drs Javier Cortés, Matthew Goetz, Erika Hamilton, Ian Krop, Hope Rugo and Sara Tolaney, including the following topics:

Introduction (0:00)
Optimizing the Management of ER-Positive Localized Breast Cancer — Matthew P Goetz, MD (7:50)
New and Novel Treatment Strategies for Localized Triple-Negative Breast Cancer (TNBC) — Erika Hamilton, MD (38:35)
Considerations in the Care of Patients with Localized HER2-Positive Breast Cancer — Ian E Krop, MD, PhD (56:03)
Evolving Clinical Decision-Making for Patients with HER2-Positive Metastatic Breast Cancer (mBC) — Javier Cortés, MD, PhD (1:18:47)
Selection and Sequencing of Therapy for ER-Positive, HER2-Negative mBC — Hope S Rugo, MD (1:40:41)
Recent Advances in the Care of Patients with Metastatic TNBC — Sara M Tolaney, MD, MPH (2:11:40)

CME information and select publications