Research To Practice | Oncology Videos

Latest Episodes:

Non-Small Cell Lung Cancer | Inside the Issue: Integrating ALK-Targeted Therapy into the Management of Localized Non-Small Cell Lung Cancer Aug 21, 2024

Show notes

Featuring perspectives from Prof Solange Peters and Prof Ben Solomon, including the following topics:

Introduction (0:00)
Significance of Biomarker Testing in Localized Non-Small Cell Lung Cancer (NSCLC) and Historical Management Paradigm for ALK-Positive Disease — Prof Peters (9:17)
Emerging Role and Practical Application of ALK-Targeted Therapy in Localized NSCLC — Prof Solomon (33:01)

CME information and select publications

Breast Cancer | Oncology Today with Dr Neil Love: Integrating Antibody-Drug Conjugates into the Management of HR-Positive and Triple-Negative Metastatic Breast Cancer Aug 16, 2024

Show notes

Featuring perspectives from Dr Sara A Hurvitz, including the following topics:

Case: A woman in her late 40s who received treatment for triple-negative breast cancer develops lung metastases 2 years later (0:00)
Clinical trials investigating TROP2-targeting antibody-drug conjugates (13:28)
Identifying and targeting HER2 in HER2 low-expressing disease (21:17)
Case: A woman in her early 50s who received treatment for Stage I breast cancer later develops multiple lesions similar to the original cancer (29:00)
Thresholds of HER2 expression and the efficacy of trastuzumab deruxtecan (T-DXd) (34:01)
Case: A woman in her late 50s receiving T-DXd for HER2-low metastatic breast cancer develops asymptomatic ground glass infiltrates in the lung (39:19)
Novel ADC strategies under investigation (48:22)

CME information and select publications

Lung Cancer | Oncology Today with Dr Neil Love: Novel Agents and Strategies in Lung Cancer Aug 14, 2024

Show notes

Featuring perspectives from Dr Melissa Johnson, Dr Ticiana Leal and Dr Manish Patel, including the following topics:

Introduction: Two Faces of Lung Cancer Research (0:00)
B7-H3-Targeted Antibody-Drug Conjugates for Lung Cancer — Dr Patel (16:14)
Potential Role of Tumor Treating Fields in the Management of Metastatic Non-Small Cell Lung Cancer — Dr Leal (32:36)
Emerging Role of Bispecific T-Cell Engaging Immunotherapy in Small Cell Lung Cancer — Dr Johnson (46:14)

CME information and select publications

Multiple Myeloma | Jesús G Berdeja, MD Aug 12, 2024

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Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Multiple Myeloma | Faculty Presentation 2: Chimeric Antigen Receptor T-Cell Therapy, Bispecific Antibodies and Antibody-Drug Conjugates for MM — Jesús G Berdeja, MD

CME information and select publications

Multiple Myeloma | Thomas Martin, MD Aug 12, 2024

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Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Multiple Myeloma | Faculty Presentation 1: Current and Emerging Therapeutic Approaches for Multiple Myeloma (MM) — Thomas Martin, MD

CME information and select publications

Multiple Myeloma | Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Multiple Myeloma Aug 12, 2024

Show notes

Featuring perspectives from Dr Jesús G Berdeja and Dr Thomas Martin, including the following topics:

Introduction: Real-World Regulatory Issues in Multiple Myeloma (MM) (0:00)
Newly Diagnosed MM (14:30)
Novel Agents for Relapsed/Refractory MM (24:58)
Chimeric Antigen Receptor T-Cell Therapy and Bispecific Antibodies (44:28)

CME information and select publications

Skin Cancer | Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Melanoma and Nonmelanoma Skin Cancers Aug 09, 2024

Show notes

Featuring perspectives from Dr Evan J Lipson, including the following topics:

Introduction: Johns Hopkins University (0:00)
Metastatic Melanoma (8:21)
Nonmetastatic Melanoma and Other Skin Cancers (34:20)

CME information and select publications

Breast Cancer | Individualizing the Selection of First-Line Therapy for Patients with Hormone Receptor-Positive Metastatic Breast Cancer Aug 07, 2024

Show notes

Featuring an interview with Dr Joyce O'Shaughnessy, including the following topics:

Overview of CDK Inhibition for Metastatic Breast Cancer (0:00)
Features of High-Risk, HR-Positive, HER2-Negative Localized Breast Cancer (7:45)
Sequencing and Selection of CDK4/6 Inhibitors (23:28)
Management of Toxicities Associated with CDK Inhibitors and Promoting Patient Adherence (45:47)
Review of Clinical Investigator Survey Results (1:01:47)

CME information and select publications

Lung Cancer | Year in Review: Clinical Investigator Perspectives on the Most Relevant New Data Sets and Advances in Immunotherapy and Other Nontargeted Approaches for Lung Cancer Aug 05, 2024

Show notes

Featuring perspectives from Dr Matthew Gubens, including the following topics:

Introduction: Risk of Autoimmune Toxicity with Checkpoint Inhibitors (0:00)
Immunotherapy in the Neoadjuvant/Adjuvant Setting (7:33)
Immunotherapy for Locally Advanced Non-Small Cell Lung Cancer (NSCLC) (15:45)
First-Line Immunotherapy for Metastatic NSCLC (24:04)
Novel Agents and Strategies (30:39)
Immunotherapy for NSCLC with a Targetable Mutation (41:34)
Small Cell Lung Cancer (47:06)

CME information and select publications

Prostate Cancer | Oncology Today with Dr Neil Love: An interview with Matthew R Smith, MD, PhD — Management of Prostate Cancer Aug 02, 2024

Show notes

Featuring an interview with Dr Matthew R Smith, including the following topics:

Selection and sequencing of androgen-targeting therapies (0:00)
Evidence-based selection of treatment for metastatic hormone-sensitive prostate cancer (25:07)
New considerations with the use of PARP inhibitors for metastatic castration-resistant prostate cancer (mCRPC) (27:44)
Role of novel radiopharmaceuticals for mCRPC (37:09)
Promising investigational approaches for prostate cancer (42:38)

CME information and select publications