Research To Practice | Oncology Videos

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Lung Cancer | Oncology Today with Dr Neil Love: Special Edition — Key Presentations on Lung Cancer from Recent Major Conferences Nov 07, 2024

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Featuring an interview with Dr Stephen V Liu, including the following topics:

Management of localized non-small cell lung cancer (NSCLC) (0:00)
First-line treatment of advanced NSCLC (10:53)
Targeted therapy for patients with NSCLC and actionable genomic alterations (30:24)
Recent FDA approvals for NSCLC (37:49)
Recent advances in small cell lung cancer (47:14)
Lurbinectidin in combination with atezolizumab as front-line maintenance therapy for patients with early-stage SCLC (52:33)

CME information and select publications

Gastrointestinal Cancers | The Implications of Recent Datasets for the Current and Future Management of Gastrointestinal Cancers — An ESMO Congress 2024 Review Nov 06, 2024

Show notes

Featuring perspectives from Dr Tanios Bekaii-Saab and Dr Philip A Philip, including the following topics:

Introduction (0:00)
Colorectal Cancer, Anal Cancer and Pancreatic Cancer — Dr Philip (1:56)
Gastroesophageal Cancers, Hepatocellular Cancer and Biliary Tract Cancers — Dr Bekaii-Saab (41:48)

CME information and select publications

Metastatic Breast Cancer | Improving Outcomes with First-Line Endocrine-Based Therapy for Patients with HR-Positive, HER2-Negative Metastatic Breast Cancer Nov 01, 2024

Show notes

Featuring perspectives from Prof Francois-Clement Bidard and Dr Kevin Kalinsky, including the following topics:

Introduction: Confronting Metastatic Breast Cancer (mBC) (0:00)
Mechanisms of Resistance to Endocrine Therapy in HR-Positive mBC; Use of Oral Selective Estrogen Receptor Degraders (SERDs) — Dr Kalinsky (13:18)
Ongoing Evaluation of Early Therapeutic Switching for HR-Positive mBC Harboring ESR1 Mutations — Prof Bidard (35:52)

CME information and select publications

Mantle Cell Lymphoma | Michael Wang, MD Oct 30, 2024

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Practical Perspectives: Optimizing the Role of BTK Inhibitors in the Management of Mantle Cell Lymphoma | Faculty Presentation — Michael Wang, MD

CME information and select publications.

Mantle Cell Lymphoma | Practical Perspectives: Optimizing the Role of BTK Inhibitors in the Management of Mantle Cell Lymphoma Oct 30, 2024

Show notes

Featuring perspectives from Dr Tycel Phillips and Dr Michael Wang, including the following topics:

Introduction: Interface Between Chronic Lymphocytic Leukemia and Mantle Cell Lymphoma (0:00)
Key Datasets — Overview and First-Line Therapy (7:16)
Faculty Case Presentations — Dr Phillips (27:03)
Key Datasets — Relapsed/Refractory Disease (35:40)
Faculty Case Presentations — Dr Wang (48:06)

CME information and select publications

HR-Positive Metastatic Breast Cancer | Oncology Today with Dr Neil Love: Potential Role of PROTAC ER Degraders in Therapy for HR-Positive Metastatic Breast Cancer (Companion Faculty Lecture) Oct 25, 2024

Show notes

Featuring a slide presentation and related discussion from Dr Erika Hamilton, including the following topics:

Targeted therapies for ER-positive breast cancer (0:00)
Clinical data with oral selective estrogen receptor degraders (2:13)
Biological rationale for and mechanism of action of proteolysis-targeting chimeras (PROTACs) (7:07)
Emerging data with PROTACs for ER-positive advanced breast cancer (9:17)
Future directions with PROTACs for breast cancer (19:21)

CME information and select publications

HR-Positive Metastatic Breast Cancer | Oncology Today with Dr Neil Love: Potential Role of PROTAC ER Degraders in Therapy for HR-Positive Metastatic Breast Cancer Oct 25, 2024

Show notes

Featuring an interview with Dr Erika Hamilton, including the following topics:

Pathophysiology and pharmacology of ER-positive breast cancer treatment (0:00)
Clinical evidence available with oral selective estrogen receptor degraders (3:46)
Mechanism of action of proteolysis-targeting chimeras (PROTACs) (13:22)
PROTACs currently in clinical development (16:39)
Case: A woman in her late 30s with HR-positive, HER2-negative metastatic breast cancer (mBC) experiencing progression on a CDK4/6 inhibitor (CDK4/6i) and an aromatase inhibitor (AI) (35:09)
Case: A woman in her early 70s with HR-positive, HER2-negative mBC that progresses on a CDK4/6i and an AI (41:16)

CME information and select publications

Chronic Myeloid Leukemia | Jorge Cortes, MD Oct 24, 2024

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Practical Perspectives: Current Management of Chronic Myeloid Leukemia | Faculty Presentation — Jorge Cortes, MD

CME information and select publications

Chronic Myeloid Leukemia | Practical Perspectives: Current Management of Chronic Myeloid Leukemia Oct 24, 2024

Show notes

Featuring perspectives from Dr Bhavana (Tina) Bhatnagar, Dr Amanda Blackmon, Dr Jorge Cortes, Dr Michael J Mauro and Dr Neil P Shah, including the following topics:

Recently presented data affecting the treatment of newly diagnosed chronic myeloid leukemia (CML) (0:00)
Case: A man in his mid 40s with newly diagnosed CML with tyrosine kinase inhibitor (TKI) tolerability issues but a good response (24:51)
Case: A woman in her mid 80s with chronic-phase CML (CP-CML) with translocation (9;22) (40:26)
Case: A woman in her mid 80s with CP-CML and notable comorbidities (43:12)
Case: A woman in her early 50s with CP-CML intolerant to dasatinib (51:22)
Case: A woman in her late 50s with CP-CML and TKI withdrawal syndrome (1:01:22)
Case: A woman in her mid 50s with accelerated-phase CML (1:08:22)
Case: A woman in her early 70s with CP-CML and a suboptimal response to second-line TKI (1:17:00)
Case: A man in his mid 30s with CP-CML and a complex variant Ph-positive translocation (1:23:24)
Case: A man in his mid 30s with CP-CML and a T315I mutation (1:28:55)

CME information and select publications

Small Cell Lung Cancer | The Implications of Recent Datasets for the Current and Future Management of Small Cell Lung Cancer — A 2024 World Conference on Lung Cancer Review Oct 23, 2024

Show notes

Featuring perspectives from Dr Jacob Sands, including the following topics:

Introduction: A man in his mid 60s with a lung nodule on lung cancer screening (0:00)
Current and Future Management of Small Cell Lung Cancer (15:42)

CME information and select publications

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