Research To Practice | Oncology Videos

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**Research To Practice | Oncology Videos**

Featuring the video recorded proceedings of events held in conjunction with important scientific symposia, live webcasts and closed meetings featuring the perspectives of renowned clinical investigators, these videos provide an overview of important advances in the management of a number of solid tumors and hematologic cancers.

Latest Episodes:

EGFR Mutation-Positive NSCLC — Fourth Annual National General Medical Oncology Summit Apr 20, 2025

Show notes

Featuring perspectives from Dr Jonathan Goldman and Dr Natasha B Leighl, including the following topics:

Introduction (0:00)
Current Management of Nonmetastatic and Metastatic EGFR Mutation-Positive Non-Small Cell Lung Cancer (NSCLC) — Prof Leighl (1:42)
Promising Novel Agents in Clinical Development; EGFR Exon 20 Mutation-Positive NSCLC — Dr Goldman (37:25)

CME information and select publications

HER2-Positive and Triple-Negative Breast Cancer — Fourth Annual National General Medical Oncology Summit Apr 19, 2025

Show notes

Featuring perspectives from Dr Aditya Bardia, Dr Virginia F Borges, Dr Harold J Burstein and Dr Joyce O'Shaughnessy, including the following topics:

Introduction (0:00)
HER2-Positive Breast Cancer — Dr O'Shaughnessy (3:13)
Triple-Negative Breast Cancer — Dr Bardia (32:56)
Personalizing Adjuvant Therapy for Patients with HR-Positive Breast Cancer — Dr Borges (57:35)
Current Role of CDK4/6 Inhibitors in the Localized Setting — Dr Burstein (1:25:15)

CME information and select publications

Oncology Nursing Update Special 2-Part Edition: Bispecific Antibodies in Lymphoma — Part 2 Apr 18, 2025

Show notes

Featuring an interview with Ms Amy Goodrich, including the following topics:

Presentation and management of follicular lymphoma (FL) (0:00)
Case: A woman in her late 70s with heavily pretreated disease experiences complete response to mosunetuzumab (24:41)
Case: A man in his early 60s with extensive diffuse large B-cell lymphoma and short response to CAR-T is successfully bridged to allogeneic transplant with glofitamab (30:15)
Case: A man in his late 50s with transformed FL has limited treatment options due to lack of social support (45:51)
Effects of bispecific antibodies in follicular and diffuse large B-cell lymphoma (52:53)

NCPD information and select publications

Ovarian Cancer — Proceedings from a Session Held During the 2025 SGO Annual Meeting on Women's Cancer® Apr 17, 2025

Show notes

Featuring perspectives from Dr Kathleen N Moore, Dr Ritu Salani, Dr Angeles Alvarez Secord and Dr Shannon N Westin, moderated by Dr Secord, including the following topics:

Introduction (0:00)
Up-Front Treatment for Advanced Ovarian Cancer (OC) — Dr Westin (2:42)
Management of Relapsed/Refractory OC — Dr Secord (23:06)
Novel Investigational Therapies for Advanced OC — Dr Moore (46:55)
Diagnosis and Management of Adverse Events Associated with Commonly Employed Therapies for Advanced OC — Dr Salani (1:08:34)

CME information and select publications

Myelofibrosis — An Interview with Dr Raajit K Rampal on Key Presentations from the 66th American Society of Hematology (ASH) Annual Meeting Apr 16, 2025

Show notes

Featuring an interview with Dr Raajit K Rampal, including the following topics:

Clinical decision-making in the initiation and stopping of systemic therapy for myelofibrosis (MF) (0:00)
Novel research strategies involving CDK4/6 inhibitors for MF (8:03)
Implications of the JUMP study for clinical practice (10:00)
Therapeutic switching strategies with JAK inhibitors for MF (12:17)
Clinical rationale for the use of luspatercept and elritercept for MF (15:35)
Emerging clinical data involving BET inhibitors for MF (16:57)
Tolerability concerns with selinexor in patients with MF (20:01)
Mechanism of and clinical data with the MDM2 inhibitor navtemadlin for MF (22:32)
Additional novel strategies under clinical investigation for MF (25:52)
Potential transformation of myeloproliferative neoplasms to acute myeloid leukemia (29:40)
Management of polycythemia vera and essential thrombocythemia (34:27)
General management principles for myeloproliferative neoplasms (37:53)

CME information and select publications

Myelofibrosis — An Interview with Dr Raajit K Rampal on Key Presentations from the 66th American Society of Hematology (ASH) Annual Meeting (Companion Faculty Lecture) Apr 16, 2025

Show notes

Featuring a slide presentation and related discussion from Dr Raajit K Rampal, including the following topics:

Overview of the current JAK inhibitor landscape (0:00)
Factors predicting clinical benefit in patients with myelofibrosis (MF) receiving ruxolitinib (3:02)
Clinical data supporting the use of fedratinib after prior ruxolitinib for MF (9:17)
Emerging clinical findings on pelabresib in combination with ruxolitinib for previously untreated MF (12:13)
Available clinical data with novel BET inhibitors (15:00)
Utility of selinexor in combination with ruxolitinib for MF previously treated with ruxolitinib (16:50)
Emerging efficacy and safety findings reported with imetelstat for MF (18:57)
Clinical findings reported with the MDM2 inhibitor navtemadlin for MF (21:15)
Available clinical data with the TGF-beta inhibitor elritercept for MF (24:05)
Other novel agents and strategies under investigation for MF (26:06)

CME information and select publications

Sarcoma and Other Connective Tissue Neoplasms — Fourth Annual National General Medical Oncology Summit Apr 14, 2025

Show notes

Featuring perspectives from Dr Rashmi Chugh and Dr Richard F Riedel, including the following topics:

Other Connective Tissue Neoplasms — Dr Chugh (0:00)
Sarcoma — Dr Riedel (28:16)

CME information and select publications

HR-Positive Breast Cancer — Fourth Annual National General Medical Oncology Summit Apr 13, 2025

Show notes

Featuring perspectives from Dr Aditya Bardia, Dr Virginia F Borges, Dr Harold J Burstein and Dr Joyce O'Shaughnessy, including the following topics:

Introduction (0:00)
CDK4/6 Inhibitors for HR-Positive Metastatic Breast Cancer (mBC) — Dr Borges (9:56)
Targeting the PTEN/PI3K/AKT Pathway in HR-Positive mBC — Dr Burstein (35:20)
Role of Oral Selective Estrogen Receptor Degraders in the Management of HR-Positive mBC — Dr O'Shaughnessy (1:03:07)
Antibody-Drug Conjugates for HR-Positive mBC — Dr Bardia (1:36:12)

CME information and select publications

Chronic Lymphocytic Leukemia — Fourth Annual National General Medical Oncology Summit Apr 12, 2025

Show notes

Featuring perspectives from Dr Nicole Lamanna and Dr Kerry Rogers, including the following topics:

Introduction (0:00)
Current Role of Covalent Bruton Tyrosine Kinase and Bcl-2 Inhibitors in Managing Chronic Lymphocytic Leukemia — Dr Lamanna (10:55)
Novel Agents and Combination Strategies — Dr Rogers (31:21)

CME information and select publications

Neuroendocrine Tumors — Fourth Annual National General Medical Oncology Summit Apr 11, 2025

Show notes

Featuring perspectives from Dr Simron Singh and Dr Jonathan Strosberg, including the following topics: