Research Ethics Reimagined

Latest Episodes:

Trust, Translation, and the Future of Federal Research With Josh Fessel, MD, PhD Oct 30, 2025

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In this episode of PRIM&R's podcast, "Research Ethics Reimagined," we speak with Dr. Josh Fessel about trust in science, translational medicine, and the challenges facing federal research. Dr. Fessel is a physician scientist who most recently served as chief medical officer and director of the Office of Translational Medicine in the National Center for Advancing Translational Sciences at NIH. He discusses lessons from the COVID-19 pandemic, ethical considerations in AI implementation, and his decision to leave federal service when directives conflicted with his values as a physician and researcher.

AI, Trust, and the Future of Bioethics With Vardit Ravitsky, PhD Sep 22, 2025

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In this episode of PRIM&R's podcast, "Research Ethics Reimagined," we explore the intersection of artificial intelligence, trust, and bioethics with Dr. Vardit Ravitsky, President and CEO of the Hastings Center for Bioethics. Dr. Ravitsky discusses the rapid implementation of AI in healthcare and biomedical research, strategies for combating misinformation, and maintaining organizational values during challenging political times. She also shares practical advice for emerging professionals in bioethics and biomedical research.

Human Challenge Studies With Wilbur H. Chen, MD, and Jake Eberts Aug 29, 2025

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In this episode of "Research Ethics Reimagined," we explore human challenge studies for shigellosis, examining their role in vaccine development and the ethical considerations surrounding intentional infection of healthy volunteers. Our guests are Dr. Wilbur H. Chen, the Frank M. Calia, MD Endowed Professor and Chief of the Division of Geographic Medicine at the University of Maryland School of Medicine, and Jake Eberts of 1Day Sooner, who is a former participant in a Shigella challenge trial.

The Intersecting Ethics of Canine and Human Cancer Research With Mark Mamula, PhD Jul 29, 2025

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In this episode of PRIM&R's podcast, "Research Ethics Reimagined," we explore groundbreaking cancer vaccine research for dogs with potential implications for human cancer treatment. Our guest is Dr. Mark Mamula, Professor at the Yale School of Medicine and leading researcher in immunology and innovative vaccine development.

The First 100 Days: Navigating Uncertainty in Research Oversight With Mark Barnes, JD, LLM Jun 05, 2025

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In this episode of "Research Ethics Reimagined," Mark Barnes, JD, LLM, a partner in the healthcare and life sciences practice at Ropes and Gray LLP in Boston shares his thoughts on the first 100 days of the new administration and identifies the ongoing legal challenges that affect the research oversight community.

Community Engaged Research With Monica L. Albertie Apr 30, 2025

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In this episode of "Research Ethics Reimagined," we explore community-engaged research and its role in advancing health equity, particularly in cancer care. Our guest is Monica L. Albertie, Director of Research Operations for Community Outreach and Engagement at the Mayo Clinic Comprehensive Cancer Center. She provides operational leadership for cancer-focused community outreach and community-engaged research aimed at reducing the cancer burden. In addition to her leadership role, Monica also serves as an Assistant Professor of Health Care Administration at the Mayo Clinic College of Medicine and Science.

Progress, Gaps, and the Future of Women’s Health with Doretha Walker, MPA, PhD, and Brenda Jamerson, PharmD Mar 31, 2025

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In this episode, Doretha Walker, MPA, PhD, and Brenda Jamerson, PharmD, join us to explore the evolution of women’s health research since the NIH Revitalization Act of 1993. They’ll discuss how women’s health understanding has evolved, key advancements, and the impact of the lack of diversity in clinical trials. Our guests will also highlight critical gaps in women’s health research and how we can address them.

Ethics in Orbit With Rachael Dempsey Mar 25, 2025

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During our first episode of Season 2 of Research Ethics Reimagined, Guest Host Robert Nobles, DrPH, MPH, CIP takes us beyond our usual conversations into the cosmos—literally. Our guest is Rachael Dempsey, the Chief Operations and Communications Officer at the Translational Research Institute for Space Health, also known as TRISH. TRISH is at the forefront of safeguarding human health in space, working alongside NASA and leading institutions like Baylor College of Medicine, MIT, and Caltech to tackle the challenges of long-duration space travel.

Exploring the VA’s Million Veteran Program With Sumitra Muralidhar, PhD, and Jason Vassy, MD Dec 16, 2024

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In this episode of PRIM&R's podcast, "Research Ethics Reimagined," we discuss the research of the U.S. Department of Veterans Affairs' Office of Research and Development, in particular the Million Veteran Program (MVP). The MVP is a national research program looking at how genes, lifestyle, military experiences, and exposures affect health and wellness in veterans. Since launching in 2011, 1 million veterans have joined MVP, making the MVP the largest research effort at VA to improve health care for veterans and one of the largest research programs in the world studying genes and health, according to the VA. We’ll speak with Drs. Muralidhar and Vassy to learn more.

Connecting Communities and Researchers with Caleila Burrell, Allison Rusgo, and Amy Carroll-Scott, PhD Nov 13, 2024

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In this episode of PRIM&R's podcast, "Research Ethics Reimagined," we explore the Promise Zone Research Connection (PZRC) and its Community Research Review Board (CRRB) in West Philadelphia. Our guests are Caleila Burrell, Project Coordinator for the PZRC and West Philadelphia resident; Allison Rusgo, Associate Clinical Professor at Drexel University and doctoral candidate at the School of Public Health; and Dr. Amy Carroll-Scott, Associate Professor and Chair of the Department of Community Health and Prevention at Drexel Dornsife School of Public Health.

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