Real Life Pharmacology &#8211; Pharmacology Education for Health Care Professionals

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Simethicone (Gas-X) Pharmacology Podcast Mar 23, 2023

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On this podcast episode, I discuss simethicone pharmacology, adverse effects, drug interactions, and much more!

Simethicone is primarily used for anti-gas purposes. It is most often used on an as needed basis for relief of flatulence and bloating associated with gas.

Systemic absorption is minimal with simethicone so the occurrence of any systemic-type side effects at therapeutic doses is low.

Simethicone may interfere with levothyroxine absorption. Timing levothyroxine at least a few hours prior to simethicone should help reduce the significance of this interaction.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Fosinopril (Monopril) Pharmacology Podcast Mar 16, 2023

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On this podcast episode, I discuss fosinopril (Monopril) pharmacology, adverse effects, drug interactions and much more.

Fosinopril is an ACE inhibitor so it should absolutely NOT be used in pregnancy as it poses fetus risks.

Like other ACE inhibitors, hyperkalemia, cough, angioedema, and acute renal failure represent possible risks in using fosinopril.

Drugs that can raise potassium when used in combo with fosinopril include spironolactone, trimethoprim, calcineurin inhibitors, and heparin.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Haloperidol (Haldol) Pharmacology Podcast Mar 09, 2023

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On this episode of the Real Life Pharmacology podcast, I discuss haloperidol pharmacology, adverse effects, drug interactions and much more.

Haloperidol comes in multiple dosage forms. Be very careful with the use of injectable haloperidol as there is an immediate and extended release formulation.

Haloperidol is a dopamine antagonist which means that EPS adverse effects are going to be concerning.

In hospice patients, haloperidol is frequently used for its antiemetic properties as well as its potential to help end-of-life restlessness and agitation.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Promethazine (Phenergan) Pharmacology Podcast Mar 02, 2023

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In this promethazine pharmacology podcast, I discuss its mechanisms of action, side effects, important drug interactions, and much more.

Promethazine has anticholinergic and dopamine-blocking activity which contributes to the adverse effect profile as well as its efficacy.

There is a boxed warning with promethazine to avoid the use of this medication in patients under the age of 2 due to respiratory depression.

Promethazine IV is considered a high-risk route of administration and should be avoided if possible.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Loperamide (Imodium) Pharmacology Podcast Feb 23, 2023

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In this episode, I discuss loperamide (Imodium) pharmacology, adverse effects, and drug interactions.

Loperamide has opioid-type activity in the gut but has extremely low oral bioavailability. This allows it to be used for diarrhea but at lower doses won’t cause systemic opioid-like effects.

Loperamide abuse has been reported. Excessive dosages can increase the risk of cardiac arrest and other cardiovascular concerns.

Medication causes of diarrhea should be ruled out prior to starting a medication like loperamide. I discuss numerous medications that can cause diarrhea in this podcast.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Calcium Carbonate Pharmacology Podcast Feb 16, 2023

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I discuss calcium carbonate pharmacology, adverse effects, drug interactions, and more in this podcast episode.

Calcium tends to have a constipating effect and the higher the dose, the more likely patients are to experience this adverse effect.

Binding interactions are a major problem with oral calcium carbonate. I lay out numerous examples of this on the podcast.

There are a few medications that can increase calcium levels in the blood. Thiazide diuretics are a commonly used antihypertensive that may contribute to hypercalcemia.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Ramelteon (Rozerem) Pharmacology Podcast Feb 09, 2023

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On this episode, I discuss the pharmacology, adverse effects, and drug interactions of ramelteon (Rozerem).

Ramelteon is primarily only helpful for sleep onset and generally is not that helpful in sleep maintenance.

CNS depressant drug interactions will be a common concern to monitor. Opioids, benzodiazepines, and alcohol are common sedatives that can add to the effects of ramelteon.

Some of the CYP enzymes break down Ramelteon. I discuss this in greater length in this podcast episode.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Thiamine (Vitamin B1) Pharmacology Podcast Feb 02, 2023

Show notes

In this podcast episode, I discuss thiamine pharmacology and its important role in energy production.

In patients with alcohol use disorder, thiamine deficiency can be somewhat common.

Wernicke’s encephalopathy can result from thiamine deficiency in patients with alcohol use disorder.

Common symptoms from Wernicke’s encephalopathy can include confusion, lethargy, and other central nervous system issues. Thiamine replacement can help treat this issue.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

Support The Podcast and Check Out These Amazing Resources!

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)