Plenary Session

Latest Episodes:

2.05 Reup! Cancer Screening 101 with Dr. Adam Obley Jul 31, 2019

Show notes

In this REUP episode, we replay a section of our interview with Dr. Adam Obley of OHSU: a primer on cancer screening. This audio was first aired on episode 2.03. Not So Silver Lining: doi.org/10.1001/archinternmed.2011.73 Mammography Screening: Truth, Lies and Controversy: www.crcpress.com/Mammography-Screening-Truth-Lies-and-Controversy/Gotzsche/p/book/9781846195853 Back us on Patreon! www.patreon.com/plenarysession

2.04 Reup! Tumor-Treating Fields for Glioblastoma with Dr. Michael Hayes Jul 30, 2019

Show notes

In this REUP episode, we replay a section of our interview with Dr. Michael Hayes of Kaiser Permanente. This audio was first aired on episode 2.01. The interview is on the relationship between conflict of interest and editorial stance on tumor-treating fields for glioblastoma multiforme. TTF: doi.org/10.1016/j.jcpo.2019.100189 Back us on Patreon! www.patreon.com/plenarysession

2.03 Dr. Charles Moertel and the Modern Oncologist & Cancer Screening 101 with Dr. Adam Obley Jul 23, 2019

Show notes

This week we launch a new segment on Plenary Session: Question of the Week! We invite Dr. Sven Olson on to ask a sample hematology/oncology boards question and we invite Audrey Tran on to ask a question from a medical student. Before that, we talk about the legacy of Dr. Charles Moertel and how modern oncologists, in contrast, will be remembered. We end the episode with an interview with Dr. Adam Obley of OHSU -- his fourth appearance on the podcast! -- on cancer screening. Dr. Moertel's obituary: https://www.nytimes.com/1994/06/29/obituaries/charles-moertel-66-studied-treatment-and-cost-of-cancer.html Faith Lost, a Doctor Turns Bitter: https://www.latimes.com/archives/la-xpm-1993-09-12-mn-34516-story.html Not So Silver Lining: doi.org/10.1001/archinternmed.2011.73 Mammography Screening: Truth, Lies and Controversy: https://www.crcpress.com/Mammography-Screening-Truth-Lies-and-Controversy/Gotzsche/p/book/9781846195853 Back us on Patreon! www.patreon.com/plenarysession

2.02 BONUS! Improving Access to Prescription Drugs through Policy Change with Dr. Stacie Dusetzina Jul 17, 2019

Show notes

This BONUS episode is a recording of a lecture that Dr. Stacie Dusetzina of Vanderbilt University gave for grand rounds at OHSU on June 19, 2019. The lecture is on the cost of prescription drugs and out-of-pocket spending. Back us on Patreon! www.patreon.com/plenarysession

2.01 Selinexor, ECHELON-2, Parachutes, Tumor-Treating Fields, & MedTwitter Jul 12, 2019

Show notes

Welcome to season 2! We're starting this season off with a little bit of everything: a critique of the FDA's accelerated approval of selinexor for penta-refractory multiple myeloma; an interview with Dr. John Reneau of Ohio State University on ECHELON-2 (brentuximab vedotin in t-cell lymphomas); an interview with Dr. Michael Hayes of Kaiser Permanente on parachutes in medicine plus the relationship between conflict of interest and editorial stance on tumor-treating fields for glioblastoma multiforme; and an interview with Dr. Stacie Dusetzina - a leading researcher in health care policy and the cost of cancer drugs, and an avid Twitter user - of Vanderbilt University on #MedTwitter. ECHELON-2: doi.org/10.1016/S0140-6736(18)32984-2 Facing Our Mistakes: doi.org/10.1056/NEJM198401123100211 Parachutes: doi.org/10.9778/cmajo.20170088 TTF: doi.org/10.1016/j.jcpo.2019.100189 Impact of Disclosing Financial Ties: doi.org/10.1001/archinternmed.2010.39 Back us on Patreon! www.patreon.com/plenarysession

1.68 Voxeletor with Dr. Olson & Humanizing Cancer, Defining Cancer, and more with Dr. David Steensma Jul 05, 2019

Show notes

We begin this week's episode by breaking down the recent phase III trial on voxeletor in sickle cell disease with Dr. Sven Olson of OHSU. Next, we feature guest Dr. David Steensma of the Dana-Farber Cancer Institute in a far-reaching interview on being well-read, running a small lab, humanizing cancer, learning from our past use of erythropoiesis-stimulating agents, understanding the headache of contract research organizations, defining cancer, and more! Voxeletor in Sickle Cell: doi.org/10.1056/NEJMoa1903212 Don't Mention It: doi.org/10.1200/JCO.2008.17.7238 The Raven: doi.org/10.1200/JCO.2017.76.3458 Erythropoietin Use in Cancer: doi.org/10.1200/JCO.2005.05.036 Contract Research Organizations: doi.org/10.1002/cncr.29994 Back us on Patreon! www.patreon.com/plenarysession

1.67 MONALEESA-7 and the Cost of Cancer Drugs with Dr. Stacie Dusetzina Jun 27, 2019

Show notes

This week we begin the episode by discussing MONALEESA-7 and why ribociclib has been shown to increase overall survival while palbociclib has not. We finish the episode with an in-depth interview with Dr. Stacie Dusetzina of Vanderbilt University on her work in pharmacoeconomics, specifically we discuss her work on the market value of cancer drugs. MONALEESA-7: doi.org/10.1056/NEJMoa1903765 Free drug samples are a marketing tool: doi.org/10.2105/AJPH.2007.114249 Back us on Patreon! www.patreon.com/plenarysession

1.66 Employing Medical Writers & Frequentist vs Bayesian Methods with Dr. Allen Pannell Jun 20, 2019

Show notes

This week we open with a critical take on our current system of disseminating scientific research, specifically focusing on the prevalence of -- and dependence on -- medical writers. In the second half of the episode, we interview Dr. Allen Pannell of the Haslam College of Business at the University of Tennessee on using a Frequentist approach vs a Bayesian approach in the context of a single clinical trial. Frequentist vs Bayesian: doi.org/10.1136/bmjopen-2018-024256 Dr. Pannell's breast cancer support group: https://www.breastconnect.org/ Dr. Pannell's research project: http://tinyurl.com/peerErPrHer2 Back us on Patreon! www.patreon.com/plenarysession

1.65 BONUS! Focusing and Building Your Presence on Twitter Jun 12, 2019

Show notes

In this BONUS episode we give advice on how to use Twitter effectively: how to focus your content, how to build your Twitter following, and how to conceptualize of the platform as an information network. Back us on Patreon! www.patreon.com/plenarysession

1.64 Effectiveness of Cancer Screening with Dr. Joaquín Chapa and POLO with Dr. Emerson Chen Jun 06, 2019

Show notes

This week we discuss the recent paper "Interpreting the Effectiveness of Cancer Screening From National Population Statistics: Is It Sound Practice?" with its author, Dr. Joaquín Chapa of OHSU. We then revisit the POLO trial with Dr. Emerson Chen of OHSU, who disagrees with last episode's analysis. Effectiveness of Screening: doi.org/10.1016/j.mayocp.2019.02.016 POLO: doi.org/10.1056/NEJMoa1903387 Back us on Patreon! www.patreon.com/plenarysession

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