Plenary Session

Latest Episodes:

2.55 Hydroxychloroquine for COVID-19, ASCO, QOTW, Private Equity in Medicine with Dr. Jane Zhu Jun 05, 2020

Show notes

We start this week's episode by covering some recent research: After thoroughly critiquing the recent randomized trial of hydroxychloroquine for postexposure prophylaxis for COVID-19, we then discuss the five abstracts selected for plenary sessions at the recent virtual meeting of the American Society of Clinical Oncology. We transition from there to a Question from a Medical Student with Audrey Tran of Oregon Health & Science University on the recent decision to make the USMLE Step 1 exam pass/fail. Finally, we end with an interview with Dr. Jane Zhu, also of OHSU, on her current research and her new paper published in JAMA titled, "Private Equity Acquisitions of Physician Medical Groups Across Specialties, 2013-2016". Dr. Zhu first guest-starred on Plenary Session in episode 1.31. Hydroxychloroquine: doi.org/10.1056/NEJMoa2016638 JAVELIN: https://meetinglibrary.asco.org/record/186872/abstract ECOG-ACRIN: https://meetinglibrary.asco.org/record/186884/abstract ENDURANCE: https://meetinglibrary.asco.org/record/186906/abstract KEYNOTE-177: https://meetinglibrary.asco.org/record/186928/abstract ADAURA: https://meetinglibrary.asco.org/record/191929/abstract Private Equity Acquisitions: doi.org/10.1001/jama.2019.21844 Listen to the audiobook of Malignant with a free 30-day trial from Audible! https://www.audible.com/pd/B08864KFHW/?source_code=AUDFPWS0223189MWT-BK-ACX0-195112&ref=acx_bty_BK_ACX0_195112_rh_us Back us on Patreon! www.patreon.com/plenarysession

2.54 Classical Hematology Chat on Thrombosis in COVID-19 & Drugs for COVID-19 with Dr. Walid Gellad May 31, 2020

Show notes

This week we talk all things COVID-19! We start with an in-depth Classical Hematology Chat with Dr. Sven Olson and Dr. Joseph Shatzel of Oregon Health & Science University on thrombosis and anticoagulation in COVID-19, touching on a number of recent studies. We then turn to a conversation with Dr. Walid Gellad of the University of Pittsburgh on new pharmaceutical treatments for COVID-19. Tang et al. paper: doi.org/10.1111/jth.14768 Prospective autopsy study: doi.org/10.7326/M20-2566 COVID-19 compared to H1N1: doi.org/10.1056/NEJMoa2015432 Hypercoagulability of COVID-19: doi.org/10.1111/jth.14850 JACC letter: doi.org/10.1016/j.jacc.2020.05.001 JACC podcast: https://podcasts.apple.com/us/podcast/association-treatment-dose-anticoagulation-in-hospital/id932118437?i=1000474262300 Venous Thromboembolism in COVID-19: doi.org/10.1111/jth.14888 Back us on Patreon! www.patreon.com/plenarysession

2.53 Why Agreeing 65% with Someone is Important & COVID-19 Health Policy with Dr. Daniel Morgan May 23, 2020

Show notes

This week we discuss why being open-minded enough to agree partially with someone - instead of taking an all-or-nothing approach to a discourse - is important. We also sit down with epidemiologist Dr. Daniel Morgan of the University of Maryland School of Medicine to critique the public health policy concerning COVID-19 transmission. Back us on Patreon! www.patreon.com/plenarysession

2.52 Malignant Audiobook, PROfound trial, & Literature and Medicine with Dr. Adam Cifu May 16, 2020

Show notes

This week we have an announcement -- the audiobook of "Malignant: How Bad Policy and Bad Evidence Harm People with Cancer", written and narrated by our host Vinay Prasad, is available now on Amazon, iTunes, and Audible! We also have an in-depth journal club for you on the findings of the PROfound trial as published in a new paper out in the New England Journal of Medicine titled "Olaparib for Metastatic Castration-Resistant Prostate Cancer". Finally, we end the episode with an interview with Dr. Adam Cifu of the University of Chicago on literature, medicine, maintaining a feeling of normalcy and self during COVID-19, and more! Listen to Malignant with a free 30-day trial of Audible: https://www.audible.com/pd/B08864KFHW/?source_code=AUDFPWS0223189MWT-BK-ACX0-195112&ref=acx_bty_BK_ACX0_195112_rh_us PROfound: doi.org/10.1056/NEJMoa1911440 Crossover: doi.org/10.1093/annonc/mdy116 Back us on Patreon! www.patreon.com/plenarysession

2.51 BONUS! Clinical Trials Part 3 May 13, 2020

Show notes

This BONUS lecture was a talk given to the Hematology/Oncology fellows at Oregon Health & Science University. It's part three of a three-part series on clinical trials. Back us on Patreon! www.patreon.com/plenarysession

2.50 Neil Ferguson, Ending Lockdown, & Updates on COVID-19 Management with Dr. Benjamin Singer May 07, 2020

Show notes

This week's topic is all things COVID-19 -- we discuss the viral scandal of British epidemiologist Neil Ferguson's actions and how it reflects (or doesn't) on his work, we talk about the nuances of how to end lockdowns, and we bring back Dr. Benjamin Singer, a pulmonary and critical care physician at Northwestern University, to address updates in the ICU management of COVID-19. Invisible Pandemic: doi.org/10.1016/S0140-6736(20)31035-7 Back us on Patreon! www.patreon.com/plenarysession

2.49 COVID-19 Contrarians, Remdesivir, & Book Club on "Malignant" with OHSU HemOnc Fellows May 02, 2020

Show notes

This week we begin with a monologue on the recent controversy surrounding Dr. John Ioannidis's published opinions on the COVID-19 pandemic. We end with a group discussion with Oregon Health & Science University's Hematology/Oncology fellows on our host's, Vinay Prasad's, new book "Malignant: How Bad Policy and Bad Evidence Harm People with Cancer." Expressing different views on COVID-19: https://www.statnews.com/2020/04/27/hear-scientists-different-views-covid-19-dont-attack-them/ Malignant: www.amazon.com/Malignant-Policy-Evidence-People-Cancer/dp/1421437635 Back us on Patreon! www.patreon.com/plenarysession

2.48 BONUS! Introduction to Malignant: How Bad Policy and Bad Evidence Harm People with Cancer Apr 25, 2020

Show notes

This week we have a BONUS episode for you! As a teaser to the forthcoming audiobook of "Malignant: How Bad Policy and Bad Evidence Harm People with Cancer" by Dr. Vinay Prasad (our host), Audrey Tran and Ian Straehley have set the introduction of the book to music they composed and arranged themselves. You can buy the print version of Malignant from Amazon: https://www.amazon.com/Malignant-Policy-Evidence-People-Cancer-dp-1421437635/dp/1421437635/ Back us on Patreon! www.patreon.com/plenarysession

2.47 Remdesivir, Cloth Masks, & Incentives for COVID-19 Drug Development with Dr. Ameet Sarpatwari Apr 16, 2020

Show notes

This week we start with an in-depth monologue on various new developments surrounding COVID-19, specifically the new study in NEJM on the compassionate use of remdesivir as well as the CDC's advice for the general public to wear cloth masks. We end with an interview with Dr. Ameet Sarpatwari of Harvard Medical School on how to create a more effective pharmaceutical system, the CREATES Act of 2019, developing fair and equitable drugs to treat COVID-19, and how to create a just system that balances the need for innovation with the need for access. Dr. Ameet Sarpatwari is the Assistant Director of PORTAL. Compassionate Use of Remdesivir: doi.org/10.1056/NEJMoa2007016 U.S. Gene Therapy Trials: doi.org/10.1001/jama.2019.22214 NIH Fair Pricing Condition: doi.org/10.7326/M19-2576 Back us on Patreon! www.patreon.com/plenarysession

2.46 Psychology Unearthed by COVID-19 Precautions & Polygenic Risk Score with Dr. Venk Murthy Apr 11, 2020

Show notes

This week we have a far-reaching monologue on COVID-19 and how people are reacting to the public health recommendations concerning COVID-19 (such as cancelling conferences and school, maintaining 6+ feet of distance, wearing cloth masks). We end with an insightful interview with Dr. Venk Murthy on polygenic risk score and, at the end, a bit about how the world of science is failing to combat hype. Back us on Patreon! www.patreon.com/plenarysession

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