PeerView Clinical Pharmacology CME/CNE/CPE Audio Podcast

Latest Episodes:

Athena Philis-Tsimikas, MD - Episode 1: Current Guidance and Indications for Basal Insulin in Patients With T2DM Jul 24, 2023

Show notes

Go online to PeerView.com/KNZ860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Insulin is indispensable to the treatment of diabetes, but its use in people with diabetes presents numerous well-known challenges. As many as 40% of people with T2DM require insulin therapy, but only about one-third initiate basal insulin. How can endocrinologists and other healthcare providers ease the treatment burden for these patients? Part of the answer may lie in once-weekly basal insulins. This PeerView inQuiry challenges you to examine the role of once-weekly basal insulins and how they may help to improve outcomes in patients with diabetes. Four assessment questions will keep you on your toes, and an expert will share short, authoritative explanations on the latest clinical data, rationale for use, dosing and tips and strategies for helping patients achieve glycemic targets with less frequent basal insulin injection. Upon completion of this activity, participants should be better able to: Compare the efficacy, safety, administration, and dosing frequency of once-weekly with once-daily basal insulins; and Identify patients with T2DM that are not meeting individualized glycemic goals and who may benefit from basal insulin therapy, including once-weekly formulations, as they become available

Athena Philis-Tsimikas, MD - Episode 3: Practical Considerations for Once-Weekly Basal Insulin Therapy Jul 24, 2023

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Athena Philis-Tsimikas, MD - Episode 4: Exploring Therapeutic Potential of Once-Weekly Basal Insulin Therapy Jul 24, 2023

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Athena Philis-Tsimikas, MD - Episode 2: Overcoming Clinical Inertia in Patients With T2DM Jul 24, 2023

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Ghassan Abou-Alfa, MD, MBA - Renovating the Clinical Rulebook for HCC: Multidirectional Management With Innovative Immunotherapy and Targeted Platforms Jul 06, 2023

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Go online to PeerView.com/UUY860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Approaches to managing patients with hepatocellular carcinoma (HCC) are undergoing renovation! A recent wave of improved therapeutic regimens, including immunotherapy/anti-VEGF combinations (eg, atezolizumab and bevacizumab), dual immunotherapy combinations (ie, durvalumab-tremelimumab), and next-generation TKIs (ie, lenvatinib) has been introduced in the upfront setting. Recent additions to the second-line setting have delivered improved options for patients with HCC including immune checkpoint inhibitors (eg, pembrolizumab and tislelizumab) and multikinase inhibitors (ie, cabozantinib and regorafenib). Emerging data on other up-and-coming targeted platforms are forthcoming, including evidence for perioperative applications in earlier disease settings. With all of these developments, how should we update our clinical rulebooks for treating HCC? This activity, based on a recent live symposium, uncovers innovative treatment strategies in early and intermediate HCC and presents validated and emerging strategies in advanced HCC. The unique Tumor Board format uses case-based scenarios to facilitate an interactive discussion covering practical guidance you can use to renovate your own clinical rulebook. Upon completion of this activity, participants should be better able to: Examine the latest clinical evidence supporting the use of immunotherapy, targeted therapy, and combination regimens for the management of HCC; Integrate individualized treatment plans for patients with HCC based on the latest clinical evidence, expert recommendations, and patient-specific factors; and Employ team-based strategies and practical considerations when integrating novel HCC regimens, including monitoring, patient consultation, and adverse event management

Allison Agwu, MD, ScM, FAAP, FIDSA - Retaining and Re-Engaging People Living With HIV in Care: A Unique Look at Challenges and Opportunities From the Perspective of the Patient, Navigator, and Provider Jul 06, 2023

Show notes

Go online to PeerView.com/GRT860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert provider, navigator, and two patients explore the factors that contribute to people living with HIV (PLWH) falling out of care and different strategies that can be used for re-engaging PLWH back into the HIV care continuum. Upon completion of this activity, participants should be better able to: Identify individual and structural factors that contribute to PLWH falling out of care; Discuss methodologies, benefits, and limitations associated with different strategies for re-engaging PLWH who are out of care; and Employ individualized and comprehensive plans to successfully re-engage PLWH in care

Naval Daver, MD - Pushing Innovation in AML: Real-World Integration of Modern Therapeutics Into Personalized Patient Management Jul 06, 2023

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Go online to PeerView.com/PYA860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Newer treatment modalities for acute myeloid leukemia (AML) have rapidly eclipsed the decades-long cytarabine-based standard of care and helped clinicians adopt more personalized management using innovative cytotoxic platforms, targeted agents (including FLT3, BCL2, and IDH inhibitors), and other unique management strategies. Clinicians can now improve patient outcomes across all AML treatment settings, while at the same time selecting the most potent, personalized option that can be designed to address a given patient’s needs. This “Seminars and Tumor Board” activity, adapted from our recent live event held at the 2023 ASCO Annual Meeting and developed in collaboration with the HealthTree Foundation for Acute Myeloid Leukemia, reveals how modern baseline assessment paired with cutting-edge prognostication has pushed patient management to new heights of innovation and changed the management of patients with AML with therapeutically relevant features (such as FLT3 or IDH mutations), patients presenting without driver mutations, or individuals with comorbid illnesses or higher-risk features. Join the AML experts for a real-world “Tumor Board”–style discussion of how the latest evidence can inform your practice. Upon completion of this activity, participants should be better able to: Summarize baseline patient-related and disease-related factors, including age, comorbidities, functional status, and cytogenetic/mutational findings, that can influence prognostication and treatment selection in AML; Cite current evidence supporting the personalized use of novel treatment modalities, including new cytotoxic platforms, targeted agents, immunotherapy, and epigenetic strategies, for the management of newly diagnosed or relapsed/refractory AML; Integrate novel therapeutics into the personalized team-based management of AML according to the results of baseline assessment, presence or absence of targetable mutations, functional status, or AML subtype; and Address care delivery considerations, including optimized dosing and safety management, when caring for patients with AML

Martina J. Porter, MD - How Do You Diagnose and Treat Hidradenitis Suppurativa? Compare Your Approach With the Experts’ Jul 06, 2023

Show notes

Go online to PeerView.com/MYV860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Hidradenitis suppurativa (HS) is a chronic and recurrent inflammatory dermatologic condition that can take a long time to diagnose because of its relative rarity and long list of differential diagnoses. In the meantime, the pain and embarrassment caused by discharge and disfiguration severely decrease the quality of life for people who are impacted. Fortunately, there are a number of biologic therapies that are approved to treat HS or are in Phase 2 and 3 trials, such as inhibitors of IL-1, IL-17F and IL-17A. This activity is designed to reduce the time to diagnosis, educate clinicians on the burden their patients face, and understand the need for emerging therapies with greater efficacy. Two faculty experts will walk you through HS management and treatment protocols, with a focus on improving your knowledge and competence to incorporate new and emerging therapies into the management of this complex disease. Upon completion of this activity, participants should be better able to: Identify signs, symptoms, and diagnostic challenges to make a timely and accurate diagnosis of hidradenitis suppurativa; Describe the burdens of disease and impact on quality of life for patients with hidradenitis suppurativa; Recognize the limitations of current therapies for hidradenitis suppurativa; and Apply clinical safety and efficacy data on emerging novel treatments for patients with hidradenitis suppurativa

John B. Buse, MD, PhD - Scoring Comprehensive T2DM Management Goals: Examining the Multifaceted Effects of GLP-1 Receptor Agonists Jul 06, 2023

Show notes

Go online to PeerView.com/ZKJ860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Type 2 diabetes mellitus (T2DM) is a worldwide health concern. With more people living longer, the prevalence of chronic comorbid diseases has increased dramatically, and there is a resurgence in diabetic complications. T2DM shares risk factors with atherosclerotic cardiovascular disease (ASCVD), the leading cause of death among patients with T2DM. Furthermore, T2DM is a leading cause of kidney failure. How can clinicians address the underlying pathophysiology and comorbid organ damage that is frequently associated with T2DM? This activity seeks to answer that question using patient cases to examine where GLP-1 receptor agonists (RAs) fit in modern treatment algorithms and help recognize the differences between GLP-1 RA options. Importantly, you’ll also hear practical strategies to help navigate the ins and outs of patient-centered care. Upon completion of this activity, participants should be better able to: Explain the rationale for using GLP-1 RAs in comprehensive T2DM management plans to optimize patient outcomes and reduce the risk of associated complications; Compare current and emerging agents targeting GLP-1 based on their mechanisms of action, dosing frequency, efficacy, safety, and tolerability profiles; Identify patients who would benefit from the multifaceted glycemic and extra-glycemic effects of GLP-1 RAs as part of comprehensive T2DM management plans; and Counsel, as a member of a multidisciplinary care team, patients with T2DM about the long-term efficacy, safety, and convenience that GLP-1 RAs have to offer as a means to achieving individualized glycemic and non-glycemic health goals

Charles L. Daley, MD - Improving Time to Diagnosis of Non-Cystic Fibrosis Bronchiectasis: The Importance of the Radiologist in Fulfilling Unmet Needs of Patients Jul 05, 2023

Show notes

Go online to PeerView.com/TXG860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, based on a recent live symposium at the American Roentgen Ray Society 2023 Annual Meeting, a radiologist and pulmonologist explain the importance of early diagnosis in non-cystic fibrosis bronchiectasis (NCFBE) and explore the intricacies of CT imaging interpretation as a tool for optimizing care for bronchiectasis. These experts also share evolving insights into the pathophysiology of bronchiectasis that have led to the development of novel and emerging therapies, in particular DPP-1 inhibitors, to address underlying inflammation associated with the disease. See if you are up to date on the latest diagnosis, treatment, and management innovations for your patients with NCFBE and receive CME/MOC credit today! Upon completion of this activity, participants should be better able to: Describe the disease burden of non-cystic fibrosis bronchiectasis (NCFBE) as a chronic progressive condition and the importance of imaging for accurate diagnosis; Recognize CT features of NCFBE to facilitate diagnosis and allow for intervention; and Explain how recent insights into the underlying mechanisms of NCFBE might address unmet treatment needs for patients with NCFBE

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