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    Science

    Osterholm Update

    A weekly report on the COVID-19 pandemic from infectious disease expert Michael Osterholm, PhD, MPH. Dr. Osterholm is the director of the Center for Infectious Disease Research and Policy (CIDRAP) at the University of Minnesota and has spent a career investigating outbreaks. Since 2005, he has emphasized supply chain and other vulnerabilities and a critical need for pandemic preparedness. In this podcast, Dr. Osterholm dissects the latest COVID-19 news, data, and guidance.

    CIDRAP’s Chris Dall, MA, is the cohost of the Osterholm Update and a reporter for CIDRAP News. http://www.cidrap.umn.edu

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    Latest Episodes:
    Episode 145: The Hospital Capacity Crisis Nov 30, 2023
    Show notes

    <p>In "The Hospital Capacity Crisis," Dr. Osterholm and Chris Dall discuss the state of the pandemic in the U.S. and around the world, the reclassification of the BA.2.86 variant as a variant of interest, and the surge in pediatric pneumonia hospitalizations in China. Dr. Osterholm also provides an update on influenza and RSV in the U.S. and shares a moment of joy from one of our listeners.&nbsp;</p> <ul> <a href="https://www.cdc.gov/respiratory-viruses/whats-new/covid-19-variant-update-2023-11-27.html#print">Update on SARS-CoV-2 Variant BA.2.86 Being Tracked by CDC</a><br> <a href="https://www.covid.gov/tests">Free at-home COVID tests</a><br> <a href="https://www.nytimes.com/2023/11/13/upshot/long-covid-disability.html">Can’t Think, Can’t Remember: More Americans Say They’re in a Cognitive Fog</a> (Francesca Paris,&nbsp;<em>New York Times</em>) </ul>


    Episode 144: A Slow Motion Tsunami Nov 16, 2023
    Show notes

    <p>In "A Slow Motion Tsunami," Dr. Osterholm and Chris Dall discuss the state of the pandemic in the U.S. and around the world, the latest data on influenza and RSV, and potential funding cuts to a federal HIV program. Dr. Osterholm also answers two ID Queries and shares his thoughts on the importance of antimicrobial resistance awareness.</p> <ul> <a href="https://www.cidrap.umn.edu/antimicrobial-stewardship/superbugs-you">Superbugs &amp; You</a> Podcast<br> <a href="/sites/default/files/DebbieGoffarticle-CID.pdf">Isolated and Lonely in a Nursing Home During the Coronavirus Disease 2019 Pandemic: A Deadly Combination for My Mom</a>&nbsp;(Debra Goff, <em>Clinical Infectious Disease)</em><br> <a href="https://www.harvardsquarelibrary.org/biographies/sara-josephine-baker/">Sara Josephine Baker</a> (<em>Harvard Square Library</em>) </ul>


    Episode 143: Immunological Chess Match Nov 02, 2023
    Show notes

    <p>In this episode, Dr. Osterholm and Chris Dall discuss national and international COVID trends, the low uptake in the latest COVID vaccine, and share thoughts about which infectious agents have pandemic potential. Dr. Osterholm also answers an ID query about influenza vaccination and shares a moment of joy from one of our listeners.</p>


    Episode 142: Long COVID, Intranasal Vaccines, & Booster Dose Timing Oct 19, 2023
    Show notes

    <p>In this episode, Dr. Osterholm and Chris Dall discuss the latest national and international COVID trends, an intranasal COVID vaccine candidate, and some recent findings on long COVID. Dr. Osterholm also answers an ID Query about the timing of COVID booster doses and shares two historic public health moments in our new "This Week in Public Health History" segment.</p>


    Episode 141: One Huge Puzzle Oct 05, 2023
    Show notes

    <p>In "One Huge Puzzle," Dr. Osterholm and Chris Dall discuss the state of the pandemic in the U.S. and around the world, the rollout of the updated mRNA vaccines, and two recently published studies on long COVID. Dr. Osterholm also shares his thoughts on the updated Novavax vaccine and answers an ID Query about COVID vaccine side effects.&nbsp;</p> <ul> <a href="https://www.washingtonpost.com/health/2021/10/01/katalin-kariko-covid-vaccines/">A one-way ticket. A cash-stuffed teddy bear. A dream decades in the making.</a> (Carolyn Johnson,&nbsp;<em>Washington Post</em>)<br> <a href="https://www.washingtonpost.com/science/2021/10/01/drew-weissman-mrna-vaccine/">A scientific hunch. Then silence. Until the world needed a lifesaving vaccine.</a> (Carolyn Johnson,&nbsp;<em>Washington Post</em>)<br> <a href="https://www.cidrap.umn.edu/anti-science/deadly-societal-force-qa-author-dr-peter-hotez-anti-science-movement">‘A deadly societal force’: A Q&amp;A with author Dr. Peter Hotez on the anti-science movement.</a> (Mary Van Beusekom,&nbsp;<em>CIDRAP News</em>)<br> <a href="https://www.scientificamerican.com/article/do-you-matter-to-others-the-answer-could-predict-your-mental-health1/">Do you ‘matter’ to others? The answer could predict your mental health.</a>&nbsp;(Francine Russo,&nbsp;<em>Scientific American</em>) </ul>


    Episode 140: Challenges of the Past, Present, and Future Sep 21, 2023
    Show notes

    <p>In this episode, Dr. Osterholm and Chris Dall discuss the state of the pandemic in the U.S. and around the world as they reflect on infectious disease challenges of the past, present, and future. Dr. Osterholm also shares his thoughts on the CDC's new vaccine recommendations and answers an ID query about outdoor transmission of SARS-CoV-2.</p> <ul> <p><a href="https://www.cidrap.umn.edu/covid-19/cdc-advisers-make-universal-covid-vaccine-recommendation">CDC advisers make universal COVID vaccine recommendation</a> (CIDRAP News, Schnirring)</p> <p><a href="https://polioeradication.org/wp-content/uploads/2023/09/22nd-Report-of-The-Independent-Monitoring-Board-IMB.pdf">Closing in on Zero: Adapting to Complexity and Risk on the Path to End Polio</a> (GPEI Independent Monitoring Board)</p> <p><a href="https://www.cdc.gov/media/releases/2023/s0411-sti.html">U.S. STI Epidemic Showed No Signs of Slowing in 2021 - Cases Continued to Escalate</a> (CDC Newsroom)</p> <p><a href="https://www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2022">Global Tuberculosis Report 2022</a> (WHO)</p> <p><a href="https://www.cdc.gov/mmwr/volumes/72/wr/mm7235a4.htm?s_cid=mm7235a4_w">Outbreak of Multidrug-Resistant Tuberculosis - Kansas, 2021-2022</a> (CDC MMWR)</p> <p><a href="https://pubmed.ncbi.nlm.nih.gov/33249484/">Outdoor Transmission of SARS-CoV-2 and Other Respiratory Viruses: A Systematic Review</a> (J Infect Dis., Bulfone et al)</p> <p><a href="https://www.hiv.gov/hiv-basics/overview/history/hiv-and-aids-timeline/#year-1981">A Timeline of HIV and AIDS</a> (hiv.gov)</p> </ul>


    Episode 139: Time for a Mindset Change Sep 07, 2023
    Show notes

    <p>In "Time for a Mindset Change," Dr. Osterholm and Chris Dall discuss the rise in COVID activity in the U.S. and around the world, a recent study on COVID in white-tailed deer, and a survey on vaccine hesitancy in pet owners. Dr. Osterholm also provides an update on avian and human influenza and shares a moment of joy from one of our listeners.&nbsp;</p> <ul> Amy's <a href="/sites/default/files/amysbeautifulplace.pdf">moment of joy</a> </ul>


    Episode 138: More Confusing Times Aug 24, 2023
    Show notes

    <p>In this episode, Dr. Osterholm and Chris Dall discuss the state of the pandemic in the U.S. and around the world, the latest research on long COVID, and the recently approved RSV vaccine for infants.</p> <ul> <a href="https://erictopol.substack.com/p/long-term-long-covid?utm_source=post-email-title&amp;publication_id=587835&amp;post_id=136246566&amp;isFreemail=false&amp;utm_medium=email">Long-term long COVID</a> (Eric Topol,&nbsp;<em>Ground Truths</em>)<br> <a href="https://www.statnews.com/2023/08/23/covid-19-has-not-yet-fallen-into-a-seasonal-pattern/?utm_campaign=morning_rounds&amp;utm_medium=email&amp;_hsmi=271352051&amp;_hsenc=p2ANqtz-98anero9akRIPazLXV4xCUocQcT17YGhYzM4lMdv-ODw8IKZvREqP1iLFOjAM7VioQcwv8Zd2HIXzkThVo3-MXbkVSSQ&amp;utm_content=271352050&amp;utm_source=hs_email">COVID-19, a disease with tricks up its sleeve, hasn’t fallen into a seasonal pattern — yet</a> (Helen Branswell,&nbsp;<em>STAT</em>)<br> Leonard's <a href="/sites/default/files/Cranes%20(3974)_70a.JPG">beautiful place</a> </ul>


    Episode 137: Variant Soup Aug 10, 2023
    Show notes

    <p>In this episode, Dr. Osterholm and Chris Dall discuss national and international COVID trends, record dengue outbreaks around the world, and the updated timeline for the new COVID booster shots. Dr. Osterholm also answers an ID query on leprosy in Florida and shares a moment of joy from one of our listeners.</p> <p>Content Warning: This week's dedication and closing include discussion about suicide awareness and prevention. For listeners who would prefer to avoid this topic, we recommend skipping 3:35-6:28 and 1:00:34-1:03:32.&nbsp;</p> <ul> <a href="https://suicidology.org/wp-content/uploads/2019/07/Resources-for-Survivors-of-Suicide.pdf">Resources for suicide loss survivors</a><br> <a href="https://www.nami.org/Support-Education/Support-Groups/NAMI-Family-Support-Group">NAMI Family Support Group</a> </ul>


    Episode 136: Perspective and Humility Jul 27, 2023
    Show notes

    <p>In "Perspective and Humility," Dr. Osterholm and Chris Dall discuss the state of the pandemic in the U.S. and internationally, a recent study on recombinant flu vaccines, and respiratory protection in healthcare settings.</p> <ul> <a href="https://www.who.int/news/item/06-07-2022-un-report--global-hunger-numbers-rose-to-as-many-as-828-million-in-2021">UN Report: Global hunger numbers rose to as many as 828 million in 2021</a> (WHO)<br> <a href="https://erictopol.substack.com/p/from-asymptomatic-covid-to-long-covid">From Asymptomatic COVID to Long COVID: Major Advances in Genetic Underpinnings</a> (Eric Topol, <em>Ground Truths</em>)<br> <a href="https://doi.org/10.1038/s41586-023-06331-x">A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection</a> (Augusto et al.,&nbsp;<em>Nature</em>)<br> <a href="https://www.medrxiv.org/content/10.1101/2023.06.29.23292056v1">Genome-wide Association Study of Long COVID</a> (Lammi et al.,&nbsp;<em>MedRxiv</em>)<br> <a href="https://www.medrxiv.org/content/10.1101/2023.07.13.23292611v1">Genetic Risk Factors for Severe and Fatigue Dominant Long COVID and Commonalities with ME/CFS Identified by Combinatorial Analysis</a> (Taylor et al.,&nbsp;<em>MedRxiv</em>)<br> <a href="https://doi.org/10.1016/j.vaccine.2023.06.056">Vaccine effectiveness of recombinant and standard dose influenza vaccines against influenza related hospitalization using a retrospective test-negative design</a> (Zimmerman et al.,&nbsp;<em>Vaccine</em>) </ul>


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