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    Science

    Osterholm Update

    A weekly report on the COVID-19 pandemic from infectious disease expert Michael Osterholm, PhD, MPH. Dr. Osterholm is the director of the Center for Infectious Disease Research and Policy (CIDRAP) at the University of Minnesota and has spent a career investigating outbreaks. Since 2005, he has emphasized supply chain and other vulnerabilities and a critical need for pandemic preparedness. In this podcast, Dr. Osterholm dissects the latest COVID-19 news, data, and guidance.

    CIDRAP’s Chris Dall, MA, is the cohost of the Osterholm Update and a reporter for CIDRAP News. http://www.cidrap.umn.edu

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    Latest Episodes:
    Episode 174: The H5N1 Pandemic Cliff: Are We at the Edge? Jan 09, 2025
    Show notes

    <p>In "The H5N1 Pandemic Cliff: Are We at the Edge?," Dr. Osterholm and Chris Dall discuss the ongoing challenge of H5N1 influenza, cover increasing trends in respiratory illness, and announce a new CIDRAP report on Chronic Wasting Disease. Dr. Osterholm also answers a listener question on H5N1 in wild birds and cats and provides a tribute to the late President Jimmy Carter.&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/chronic-wasting-disease/cwd-spillover-report-2025">Chronic Wasting Disease Spillover Preparedness and Response: Charting an Uncertain Future </a>(CIDRAP)</p> <p><a href="https://ivr.cidrap.umn.edu/">Influenza Vaccines Roadmap Initiative</a> (CIDRAP)</p> <p>Follow us on <a href="https://bsky.app/"><strong>Bluesky</strong></a>: Dr. Michael Osterholm (<a href="https://bsky.app/profile/mtosterholm.bsky.social"><strong>@mtosterholm.bsky.social</strong></a>) and CIDRAP (<a href="https://bsky.app/profile/cidrap.bsky.social"><strong>cidrap.bsky.social</strong></a>)</p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Episode 173: What Is Safe and Effective? Dec 19, 2024
    Show notes

    <p>In "What Is Safe and Effective?," Dr. Osterholm and Chris Dall cover the evolving situation with H5N1 influenza, discuss the mystery outbreak in the DRC, and review the latest trends in COVID-19, flu, and RSV. Dr. Osterholm also answers a listener question on the phrase "safe and effective" regarding vaccines. And finally, the annual reading of the Polar Express from Dr. Osterholm to his grandchildren.</p> <p><a href="https://ajph.aphapublications.org/doi/10.2105/AJPH.94.6.947">Enhancing Public Confidence in Vaccines Through Independent Oversight of Postlicensure Vaccine Safety</a> (Salmon, Moulton, Halsey; <em>AJPH</em>)</p> <p>Consider <a href="https://www.cidrap.umn.edu/support">supporting this podcast</a> and the work of CIDRAP in your end-of-year giving.</p> <p>Follow us on <a href="https://bsky.app/"><strong>Bluesky</strong></a>: Dr. Michael Osterholm (<a href="https://bsky.app/profile/mtosterholm.bsky.social"><strong>@mtosterholm.bsky.social</strong></a>) and CIDRAP (<a href="https://bsky.app/profile/cidrap.bsky.social"><strong>cidrap.bsky.social</strong></a>)</p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p>


    Episode 172: A Tunnel of Uncertainty Dec 05, 2024
    Show notes

    <p>In "A Tunnel of Uncertainty," Dr. Osterholm and Chris Dall discuss several of Trump's recent HHS nominations, the latest respiratory virus data, and two recent studies on long COVID. Dr. Osterholm also provides an update on the unfolding H5N1 situation and shares another "This Week in Public Health History" segment.&nbsp;</p> <p><a href="https://www.journalofinfection.com/article/S0163-4453(24)00293-7/fulltext">The effect of pre-COVID and post-COVID vaccination on long COVID: a systematic review and meta-analysis</a> (Chow et al., <em>Journal of Infection</em>)</p> <p><a href="https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiae556/7896333">Association of messenger RNA coronavirus disease 2019 (COVID-19) vaccination and reductions in post COVID conditions following severe acute respiratory syndrome coronavirus 2 infection in a US prospective cohort of essential workers</a> (Mak et al., <em>Journal of Infectious Diseases</em>)</p> <p><a href="https://www.cidrap.umn.edu/mto-wickedphotos">Photos</a> of Dr. Osterholm in Wicked</p> <p>Follow us on <a href="https://bsky.app/"><strong>Bluesky</strong></a>: Dr. Michael Osterholm (<a href="https://bsky.app/profile/mtosterholm.bsky.social"><strong>@mtosterholm.bsky.social</strong></a>) and CIDRAP (<a href="https://bsky.app/profile/cidrap.bsky.social"><strong>cidrap.bsky.social</strong></a>)</p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Episode 171: Serious Challenges Ahead: RFK Jr and a New HHS Nov 21, 2024
    Show notes

    <p>In "Serious Challenges Ahead: RFK Jr and a New HHS," Dr. Osterholm and Chris Dall discuss the recent nomination of RFK Jr. as Secretary of Health and Human Services. They also discuss the latest COVID data, a global increase in measles cases, and a decline in STI incidence in the United States.&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/antimicrobial-stewardship/superbugs-you">CIDRAP Superbugs &amp; You Podcast</a></p> <p>Follow us on <a href="https://bsky.app/">Bluesky</a>: Dr. Michael Osterholm (<a href="https://bsky.app/profile/mtosterholm.bsky.social">@mtosterholm.bsky.social</a>) and CIDRAP (<a href="https://bsky.app/profile/cidrap.bsky.social">cidrap.bsky.social</a>)</p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Episode 170: What Happens Now? Public Health in Uncertain Times Nov 14, 2024
    Show notes

    <p>In "What Now? Public Health in Uncertain TImes", Dr. Osterholm and Chris Dall revisit their discussion on the consequences of the US presidential election on public health. Dr. Osterholm also provides the latest update on COVID-19 and other respiratory virus trends, comments on H5N1 detection in pigs, and answers an ID query on pertussis.</p> <p><a href="https://www.cdc.gov/pertussis/vaccines/index.html">CDC Pertussis Vaccine Guidelines</a></p> <p><a href="https://www.cidrap.umn.edu/antimicrobial-stewardship/superbugs-you">CIDRAP Superbugs &amp; You Podcast</a></p> <p>Follow us on <a href="https://bsky.app/">Bluesky</a>: Dr. Michael Osterholm (<a href="https://bsky.app/profile/mtosterholm.bsky.social">@mtosterholm.bsky.social</a>) and CIDRAP (<a href="https://bsky.app/profile/cidrap.bsky.social">cidrap.bsky.social</a>)</p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Episode 169: The Most Important Episode I'll Ever Record Oct 31, 2024
    Show notes

    <p>In "The Most Important Episode I'll Ever Record," Dr. Osterholm and Chris Dall discuss the latest respiratory virus trends, two human cases of H5N1 in Missouri, and an E. coli outbreak linked to a fast food product. For the first time in his career, Dr. Osterholm also shares comments about the upcoming elections in the United States.</p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Episode 168: Better Times Oct 17, 2024
    Show notes

    <p>In "Better Times," Dr. Osterholm and Chris Dall discuss the latest COVID, H5N1, and seasonal influenza data. Dr. Osterholm also answers an ID query on the ideal timing for COVID-19 booster doses and an ID query about Marburg virus transmission.</p> <p><a href="https://www.cidrap.umn.edu/covid-19/brain-imaging-reveals-changes-linked-long-covid">Brain imaging reveals changes linked to long COVID</a> (Stephanie Soucheray, <em>CIDRAP News</em>)</p> <p><a href="https://journals.asm.org/doi/10.1128/mbio.00137-15">Transmission of Ebola viruses: what we know and what we do not know</a> (Michael Osterholm et al., <em>mBio</em>)</p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Episode 167: A Coronavirus Dance Oct 03, 2024
    Show notes

    <p>In "A Coronavirus Dance," Dr. Osterholm and Chris Dall discuss the latest COVId trends, the upcoming winter respiratory virus season, and a UN meeting on antimicrobial resistance. Dr. Osterholm also provides an update on long COVID research and shares another "This Week in Public Health History" segment.&nbsp;</p> <p><a href="https://www.covidtests.gov/">COVIDTests.gov</a></p> <p><a href="https://www.cidrap.umn.edu/covid-19/covid-19-reinfection-ups-risk-long-covid-new-data-show">COVID-19 reinfection ups risk of long COVID, new data show</a> (Jim Wappes, <em>CIDRAP News</em>)</p> <p><a href="https://www.cidrap.umn.edu/covid-19/study-sheds-new-light-severe-covids-long-term-brain-impacts">Study sheds new light on severe COVID's long-term brain impacts</a> (Lisa Schnirring, <em>CIDRAP News</em>)</p> <p><a href="https://www.cidrap.umn.edu/covid-19/common-diabetes-drug-linked-lower-rate-long-covid">Common diabetes drug linked to lower rate of long COVID</a> (Stephanie Soucheray, <em>CIDRAP News</em>)</p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Episode 166: Infectious Diseases Roulette Sep 19, 2024
    Show notes

    <p>In this episode, Dr. Osterholm and Chris Dall cover the latest infectious disease news on topics including H5N1, mpox, measles, and polio. Dr. Osterholm also answers an ID query on updated COVID-19 vaccines and gives his thoughts on a controversial study on Paxlovid.</p> <p><a href="https://www.cidrap.umn.edu/covid-19/evidence-growing-covid-antivirals-cut-poor-outcomes-long-covid-experts-say">Evidence growing for COVID antivirals to cut poor outcomes, long COVID, experts say</a> (<em>CIDRAP News</em>)</p> <p><a href="https://www.foreignaffairs.com/united-states/world-not-ready-next-pandemic">The world is not ready for the next pandemic</a> (Michael Osterholm &amp; Mark Olshaker, <em>Foreign Affairs</em>)</p> <p><a href="https://www.cdc.gov/vaccines/covid-19/clinical-considerations/interim-considerations-us.html">Interim clinical considerations for use of COVID-19 vaccines in the United States</a> (CDC)</p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Episode 165: Frustrating Times: H5N1, Mpox, & Vectorborne Disease Sep 05, 2024
    Show notes

    <p>In this episode, Dr. Osterholm and Chris Dall discuss H5N1 in cattle, mpox in the Democratic Republic of Congo, and the risk of different vectorborne diseases in the United States. Dr. Osterholm also discusses the newly available 2024-2025 COVID vaccines and shares the latest "This Week In Public Health History" segment.&nbsp;</p> <p><a href="https://www.foreignaffairs.com/united-states/world-not-ready-next-pandemic">The world is not ready for the next pandemic</a> (Michael Osterholm &amp; Mark Olshaker, <em>Foreign Affairs</em>)</p> <p><a href="https://www.cdc.gov/vaccines/covid-19/clinical-considerations/interim-considerations-us.html">Interim clinical considerations for use of COVID-19 vaccines in the United States</a> (CDC)</p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


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