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    Science

    Osterholm Update

    A weekly report on the COVID-19 pandemic from infectious disease expert Michael Osterholm, PhD, MPH. Dr. Osterholm is the director of the Center for Infectious Disease Research and Policy (CIDRAP) at the University of Minnesota and has spent a career investigating outbreaks. Since 2005, he has emphasized supply chain and other vulnerabilities and a critical need for pandemic preparedness. In this podcast, Dr. Osterholm dissects the latest COVID-19 news, data, and guidance.

    CIDRAP’s Chris Dall, MA, is the cohost of the Osterholm Update and a reporter for CIDRAP News. http://www.cidrap.umn.edu

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    Latest Episodes:
    Episode 201: The Twilight Zone of Immunization Jan 29, 2026
    Show notes

    <p>In "The Twilight Zone of Immunization," Dr. Osterholm and Chris Dall discuss recent comments from CDC officials about measles, the US withdrawal from the WHO, and the latest mpox news. Dr. Osterholm also shares an update on this winter respiratory virus season and discusses the challenges that families are facing in accessing healthcare amid immigration enforcement surges in Minnesota.</p> <p><a href="https://www.cidrap.umn.edu/influenza-general/minnesota-residents-delay-medical-care-fear-encountering-ice">Minnesota residents delay medical care for fear of encountering ICE</a> (CIDRAP)</p> <p><a href="https://www.cidrap.umn.edu/sites/default/files/page-files/Jan2726CIDRAPrelease-Unbiased%20Sci-TEC-Partnership.pdf">Press Release: CIDRAP launches new partnerships to support independent, evidence-based vaccine information</a> (CIDRAP)</p> <p>&nbsp;</p> <p>Resources for vaccine and public health advocacy:</p> <p><a href="https://www.voicesforvaccines.org/get-involved/"><strong>Voices for Vaccines</strong></a></p> <p><a href="https://familiesfightingflu.org/take-action/"><strong>Families Fighting Flu</strong></a></p> <p><a href="https://vaccinateyourfamily.org/get-involved/"><strong>Vaccinate Your Family</strong></a></p> <p><a href="https://shotatlife.org/take-action/"><strong>Shot@Life</strong></a></p> <p><a href="https://aspr.hhs.gov/MRC/Pages/index.aspx"><strong>Medical Reserve Corps</strong></a></p> <p>Learn more about the <a href="https://www.cidrap.umn.edu/vaccine-integrity-project"><strong>Vaccine Integrity Project</strong></a></p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p> <p>&nbsp;</p> <p><strong>Music:</strong></p> <p>"Beauty Flow" Kevin MacLeod (incompetech.com)<br>Licensed under Creative Commons: By Attribution 4.0 License</p>


    Episode 200: A Moment Among Moments Jan 15, 2026
    Show notes

    <p>In the 200th episode of the Osterholm Update, Dr. Osterholm and Chris Dall discuss recent changes to the childhood immunization schedule, the latest data on this year's influenza season, and an update on CIDRAP's Vaccine Integrity Project. Osterholm Update producers Dr. Sydney Redepenning and Elise Holmes also join to discuss this milestone episode and reflect on how the podcast has evolved over the years.&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/childhood-vaccines/cms-stop-requiring-states-report-childhood-vaccination-levels">CMS to stop requiring states to report childhood vaccination levels</a> (Liz Szabo, <em>CIDRAP News</em>)</p> <p><a href="https://www.washingtonpost.com/health/interactive/2025/measles-vaccine-schools-outbreaks-public-health/">U.S. vaccination rates are plunging. Look up where your school stands</a> (Weber et al., <em>The Washington Post</em>)</p> <p>Resources for vaccine and public health advocacy:</p> <p><a href="https://www.voicesforvaccines.org/get-involved/"><strong>Voices for Vaccines</strong></a></p> <p><a href="https://familiesfightingflu.org/take-action/"><strong>Families Fighting Flu</strong></a></p> <p><a href="https://vaccinateyourfamily.org/get-involved/"><strong>Vaccinate Your Family</strong></a></p> <p><a href="https://shotatlife.org/take-action/"><strong>Shot@Life</strong></a></p> <p><a href="https://aspr.hhs.gov/MRC/Pages/index.aspx"><strong>Medical Reserve Corps</strong></a></p> <p>Learn more about the <a href="https://www.cidrap.umn.edu/vaccine-integrity-project"><strong>Vaccine Integrity Project</strong></a></p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Episode 199: Flu Takes Charge Jan 02, 2026
    Show notes

    <p>In "Flu Takes Charge" Dr. Osterholm and Chris Dall give us an update on the emerging flu season, Dr. Osterholm covers a new poll that shows fewer Americans are willing to recommend the MMR vaccine, and we'll hear about the Vaccine Integrity Project's latest video.</p> <p><a href="https://www.youtube.com/watch?v=v5ZFnEfs9w0"><strong>Protecting Vaccine Integrity in 2025: Evidence, Access, and Public Trust</strong></a><br><br>Resources for vaccine and public health advocacy:</p> <p><a href="https://www.voicesforvaccines.org/get-involved/"><strong>Voices for Vaccines</strong></a></p> <p><a href="https://familiesfightingflu.org/take-action/"><strong>Families Fighting Flu</strong></a></p> <p><a href="https://vaccinateyourfamily.org/get-involved/"><strong>Vaccinate Your Family</strong></a></p> <p><a href="https://shotatlife.org/take-action/"><strong>Shot@Life</strong></a></p> <p><a href="https://aspr.hhs.gov/MRC/Pages/index.aspx"><strong>Medical Reserve Corps</strong></a></p> <p>Learn more about the <a href="https://www.cidrap.umn.edu/vaccine-integrity-project"><strong>Vaccine Integrity Project</strong></a></p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Episode 198: Gaps in the Safety Net Dec 18, 2025
    Show notes

    <p>In "Gaps in the Safety Net" Dr. Osterholm and Chris Dall discuss why we shouldn’t compare other countries’ vaccine schedules to the US schedule. Dr. Osterholm continues to cover the recent infant botulism outbreak, and he answers an ID Query about New World Screwworm.</p> <p><br>Resources for vaccine and public health advocacy:</p> <p><a href="https://www.voicesforvaccines.org/get-involved/"><strong>Voices for Vaccines</strong></a></p> <p><a href="https://familiesfightingflu.org/take-action/"><strong>Families Fighting Flu</strong></a></p> <p><a href="https://vaccinateyourfamily.org/get-involved/"><strong>Vaccinate Your Family</strong></a></p> <p><a href="https://shotatlife.org/take-action/"><strong>Shot@Life</strong></a></p> <p><a href="https://aspr.hhs.gov/MRC/Pages/index.aspx"><strong>Medical Reserve Corps</strong></a></p> <p>Learn more about the <a href="https://www.cidrap.umn.edu/vaccine-integrity-project"><strong>Vaccine Integrity Project</strong></a></p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Episode 198: Gaps in the Safety Net Dec 18, 2025
    Show notes

    <p>In "Gaps in the Safety Net" Dr. Osterholm and Chris Dall discuss why we shouldn’t compare other countries’ vaccine schedules to the US schedule. Dr. Osterholm continues to cover the recent infant botulism outbreak, and he answers an ID Query about New World Screwworm.<br><br>Resources for vaccine and public health advocacy:</p> <p><a href="https://www.voicesforvaccines.org/get-involved/"><strong>Voices for Vaccines</strong></a></p> <p><a href="https://familiesfightingflu.org/take-action/"><strong>Families Fighting Flu</strong></a></p> <p><a href="https://vaccinateyourfamily.org/get-involved/"><strong>Vaccinate Your Family</strong></a></p> <p><a href="https://shotatlife.org/take-action/"><strong>Shot@Life</strong></a></p> <p><a href="https://aspr.hhs.gov/MRC/Pages/index.aspx"><strong>Medical Reserve Corps</strong></a></p> <p>Learn more about the <a href="https://www.cidrap.umn.edu/vaccine-integrity-project"><strong>Vaccine Integrity Project</strong></a></p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Special Episode: ACIP's Hepatitis B Vaccine Decisions Dec 08, 2025
    Show notes

    <p>In this special&nbsp;episode of the podcast, Dr. Osterholm and Chris Dall discuss the ACIP's recent decision to end universal hepatitis B birth dose recommendations and the impact it will have on public health.</p> <p>Noted articles:</p> <p><br><a href="https://medium.com/@jsteier_29203/and-what-have-we-done-43b40dc32de1">…And What Have We Done?</a><br><br><a href="https://www.thebulwark.com/p/this-is-what-it-looks-like-when-rfk-wins-acip-cdc-advisory-committee-hepatitis-vaccine">This Is What It Looks Like When RFK Jr. Wins</a><br><br>Resources for vaccine and public health advocacy:</p> <p><a href="https://www.voicesforvaccines.org/get-involved/"><strong>Voices for Vaccines</strong></a></p> <p><a href="https://familiesfightingflu.org/take-action/"><strong>Families Fighting Flu</strong></a></p> <p><a href="https://vaccinateyourfamily.org/get-involved/"><strong>Vaccinate Your Family</strong></a></p> <p><a href="https://shotatlife.org/take-action/"><strong>Shot@Life</strong></a></p> <p><a href="https://aspr.hhs.gov/MRC/Pages/index.aspx"><strong>Medical Reserve Corps</strong></a></p> <p>Learn more about the <a href="https://www.cidrap.umn.edu/vaccine-integrity-project"><strong>Vaccine Integrity Project</strong></a></p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Episode 197: Fork in the Road Dec 04, 2025
    Show notes

    <p>In "Fork in the Road" Dr. Osterholm and Chris Dall discuss the changes to the CDC's vaccines and autism page and this week's meeting of the CDC's Advisory Committee on Immunization Practices. Dr. Osterholm also covers the recent infant botulism outbreak and Chris answers an ID Query about possible C. difficile vaccines.</p> <p><br><a href="https://www.cidrap.umn.edu/childhood-vaccines/after-unprecedented-autism-vaccine-messaging-change-scientists-advocates-say-cdc"><strong>After unprecedented autism-vaccine messaging change, scientists, advocates say CDC no longer trustworthy</strong></a></p> <p><a href="https://www.cidrap.umn.edu/childhood-vaccines/new-review-finds-no-evidence-support-delaying-universal-hepatitis-b-birth-dose"><strong>New review finds no evidence to support delaying universal hepatitis B birth-dose vaccination</strong></a><br><br>Resources for vaccine and public health advocacy:</p> <p><a href="https://www.voicesforvaccines.org/get-involved/"><strong>Voices for Vaccines</strong></a></p> <p><a href="https://familiesfightingflu.org/take-action/"><strong>Families Fighting Flu</strong></a></p> <p><a href="https://vaccinateyourfamily.org/get-involved/"><strong>Vaccinate Your Family</strong></a></p> <p><a href="https://shotatlife.org/take-action/"><strong>Shot@Life</strong></a></p> <p><a href="https://aspr.hhs.gov/MRC/Pages/index.aspx"><strong>Medical Reserve Corps</strong></a></p> <p>Learn more about the <a href="https://www.cidrap.umn.edu/vaccine-integrity-project"><strong>Vaccine Integrity Project</strong></a></p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Episode 196: Flu Shifts: Why Vaccines Still Matter Nov 20, 2025
    Show notes

    <p>In "Flu Shifts: Why Vaccines Still Matter," Dr. Osterholm and Chris Dall review the latest trends and flu and how this year's vaccine compares to the circulating strains. Dr. Osterholm also discusses H5N1 impact on mammals in Antarctica and answers an ID Query about infant botulism.</p> <p>&nbsp;</p> <p>Resources for vaccine and public health advocacy:</p> <p><a href="https://www.voicesforvaccines.org/get-involved/"><strong>Voices for Vaccines</strong></a></p> <p><a href="https://familiesfightingflu.org/take-action/"><strong>Families Fighting Flu</strong></a></p> <p><a href="https://vaccinateyourfamily.org/get-involved/"><strong>Vaccinate Your Family</strong></a></p> <p><a href="https://shotatlife.org/take-action/"><strong>Shot@Life</strong></a></p> <p><a href="https://aspr.hhs.gov/MRC/Pages/index.aspx"><strong>Medical Reserve Corps</strong></a></p> <p>Learn more about the <a href="https://www.cidrap.umn.edu/vaccine-integrity-project"><strong>Vaccine Integrity Project</strong></a></p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Episode 195: We Can Make a Difference Oct 30, 2025
    Show notes

    <p>NOTE: In order to align our schedule with the holidays, we will not be releasing an episode on 11/13. We'll be back with our next episode on 11/20 and will resume our biweekly release schedule.</p> <p>In "We Can Make a Difference," Dr. Osterholm and Chris Dall discuss the recent publication from CIDRAP's Vaccine Integrity Project, an upcoming collaboration between CIDRAP and NEJM Evidence, and the latest measles and respiratory virus data. Dr. Osterholm also answers an ID Query about how the government shutdown is impacting public health surveillance and shares another "This Week in Public Health History" segment.</p> <p><a href="https://www.nejm.org/doi/full/10.1056/NEJMsa2514268">Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025–2026</a> (Scott et al., New England Journal of Medicine)</p> <p><a href="https://www.youtube.com/watch?v=Lh5hP6zcVrs"><strong>Vaccine Integrity Project - Response to HHS claims about vaccines (Oct 2025)</strong></a></p> <p>Resources for vaccine and public health advocacy:</p> <p><a href="https://www.voicesforvaccines.org/get-involved/"><strong>Voices for Vaccines</strong></a></p> <p><a href="https://familiesfightingflu.org/take-action/"><strong>Families Fighting Flu</strong></a></p> <p><a href="https://vaccinateyourfamily.org/get-involved/"><strong>Vaccinate Your Family</strong></a></p> <p><a href="https://shotatlife.org/take-action/"><strong>Shot@Life</strong></a></p> <p><a href="https://aspr.hhs.gov/MRC/Pages/index.aspx"><strong>Medical Reserve Corps</strong></a></p> <p>Learn more about the <a href="https://www.cidrap.umn.edu/vaccine-integrity-project"><strong>Vaccine Integrity Project</strong></a></p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


    Episode 194: Bending Not Breaking Oct 16, 2025
    Show notes

    <p>In "Bending Not Breaking," Dr. Osterholm and Chris Dall discuss recent layoffs and layoff reversals at the CDC, comments from the administration on the MMR vaccine, and the latest respiratory virus data. Dr. Osterholm also shares an update on pertussis cases and answers an ID Query about herd immunity.</p> <p>Resources for vaccine and public health advocacy:</p> <p><a href="https://www.voicesforvaccines.org/get-involved/"><strong>Voices for Vaccines</strong></a></p> <p><a href="https://familiesfightingflu.org/take-action/"><strong>Families Fighting Flu</strong></a></p> <p><a href="https://vaccinateyourfamily.org/get-involved/"><strong>Vaccinate Your Family</strong></a></p> <p><a href="https://shotatlife.org/take-action/"><strong>Shot@Life</strong></a></p> <p><a href="https://aspr.hhs.gov/MRC/Pages/index.aspx"><strong>Medical Reserve Corps</strong></a></p> <p>Learn more about the <a href="https://www.cidrap.umn.edu/vaccine-integrity-project"><strong>Vaccine Integrity Project</strong></a></p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap"><strong>SUPPORT THIS PODCAST</strong></a></p>


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