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    Life Sciences

    NYU Langone Insights on Psychiatry

    Conversations about complex psychiatric cases and evolving treatments. Host Charles Marmar, MD, Chair of Psychiatry at NYU Grossman School of Medicine, speaks with NYU Langone faculty about diagnostic reasoning, treatment decisions, and the ethical questions that arise in clinical practice.

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    Copyright: © 2023 NYU Langone Health

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    Latest Episodes:
    Mental Health Equity (with Christin Drake, MD) Mar 26, 2024
    Show notes

    Dr. Christin Drake is Clinical Associate Professor and Vice Chair of Diversity and Equity in the Department of Psychiatry at NYU Grossman School of Medicine. On this episode, Dr. Drake discusses ongoing efforts to improve mental health equity, including by improving psychiatric services for underserved groups, gathering better data, and boosting diversity among health care providers. She also discusses the importance of integrating mental health care into perinatal services and challenges the conventional wisdom about stigma toward mental health care in the Black community.
    00:00 Introduction
    00:55 Dr. Drake's Vision for Equity in Mental Health Care
    03:46 Addressing Racial Inequities in Psychiatry: A Critical Conversation
    04:45 The Importance of Representation and Mentorship in Psychiatry
    10:32 Building Foundations for Health Equity: Data and Systemic Change
    22:16 Integrating Psychiatric Care into Perinatal Health
    33:31 Rethinking Mental Health Stigma in the Black Community
    38:08 Future Projects and Closing Thoughts

    This discussion is for educational purposes and does not substitute for individual clinical judgment or patient care.

    Senior Producer: Jon Earle


    Ketamine (with John Krystal, MD) Mar 19, 2024
    Show notes

    Dr. John Krystal is Chair of Psychiatry at the Yale School of Medicine. He is best known for leading the discovery of the rapid antidepressant effects of ketamine, which paved the way for the first major new antidepressant drug in decades. Here, Dr. Krystal talks about what we’ve learned in the five years since esketamine nasal spray was approved by the FDA, including efforts to predict treatment response, dosage and frequency, safety, and long-term impact. He also discusses advances in our understanding of alcohol use disorder and weighs in on the search for psychiatric biomarkers.
    00:00 Introduction
    01:01 Dr. Krystal's Research Journey
    03:32 What We’ve Learned Since Esketamine’s FDA Approval
    05:59 Avoiding Misuse
    08:11 Optimizing Dosage
    16:25 Predicting Treatment Outcomes
    24:17 Ketamine vs. Psychedelics
    25:48 Advances in the Treatment of Alcohol Use Disorder
    32:33 Precision Psychiatry and Personalized Treatment Approaches
    39:49 Psychiatric Biomarkers
    41:03 The Future of Psychiatric Research and Treatment

    This discussion is for educational purposes and does not substitute for individual clinical judgment or patient care.

    Senior Producer: Jon Earle


    Struggling Kids & Teens (with Robert Findling, MD) Mar 12, 2024
    Show notes

    Dr. Robert Findling is Chair of the Department of Psychiatry at the Virginia Commonwealth University School of Medicine. Here he discusses recent advances in pediatric mental health, including his own research on aggression and schizophrenia in young people. Dr. Findling also shares his thoughts on the crisis of teen suicide, the lingering impact of COVID-19 on children’s mental health, and the need for early and collaborative interventions.
    00:00 Introduction
    00:46 Clinical and Research Journey
    02:56 Aggression with impulsivity and reactivity (AIR)
    06:48 Precision Pediatric Psychiatry
    15:34 Schizophrenia
    20:31 What Kids Need to Thrive
    23:10 Teen Suicide
    25:09 Role of Schools and Primary Care
    30:58 Loneliness Epidemic Among Children
    32:32 Improving Access to Pediatric Mental Health Care
    40:00 Bipolar Disorder
    43:24 Future Research and Hope for Young Patients
    45:11 Conclusion: Importance of Early Intervention

    This discussion is for educational purposes and does not substitute for individual clinical judgment or patient care.

    Senior Producer: Jon Earle


    Frontiers of Psychopharmacology (with Charles Nemeroff, MD, PhD) Mar 05, 2024
    Show notes

    Dr. Charles Nemeroff is Chair of the Department of Psychiatry and Behavioral Sciences at the University of Texas-Austin's Dell Medical School. He is also co-director of the Center for Psychedelic Research and Therapy, and director of the Institute for Early Life Adversity Research. His research is focused on the pathophysiology of mood and anxiety disorders with a focus on the role of child abuse and neglect as a major risk factor.
    00:00 Introduction
    00:52 Dr. Nemeroff's Research Journey
    01:55 Childhood Maltreatment as Risk Factor
    04:53 Advances and Challenges in Precision Psychiatry
    07:33 Psychedelic Medicine (incl. blinding issues and potential adverse events)
    20:50 How Psychedelics Disrupt the "Circle of Hell"
    30:00 Psilocybin as Potential Treatment for Anorexia Nervosa
    38:32 Screening for Childhood Maltreatment
    41:30 Transcranial Magnetic Stimulation (TMS)
    44:14 Focused Ultrasound
    46:32 Prescribing MAOIs
    49:34 Conclusion

    This discussion is for educational purposes and does not substitute for individual clinical judgment or patient care.

    Senior Producer: Jon Earle


    Empathy Training (with Helen Riess, MD) Feb 27, 2024
    Show notes

    Dr. Helen Riess is Associate Clinical Professor of Psychiatry at Harvard Medical School and Director of Empathy Research and Training in the Psychotherapy Research Group at Massachusetts General Hospital. She is also Founder and Chief Executive Officer at Empathetics, a company that provides science-based empathy and interpersonal skills training for healthcare professionals. Her research focuses on improving empathy and relational skills in physicians.
    00:00 Introduction
    01:14 Defining Empathy
    03:38 Empathy and Burnout
    05:00 Care for the Caregiver
    07:52 Exquisite Empathy and Burnout
    09:18 Building Empathy and Avoiding Overburden
    10:45 Developing Boundaries in Clinical Practice
    11:45 Training and Teaching Empathy
    13:42 Model for Recognizing Emotion in Others
    15:11 Becoming Emotion Detectives
    19:31 Leadership's Role in Creating Supportive Workplaces
    23:22 Benefits of Empathy Training
    29:07 Technology and Empathy Training
    34:18 Research on MDMA-Assisted Psychotherapy
    37:43 Building Empathy and Compassion
    40:07 Taking Small Steps Towards Empathy
    42:32 Resources for Building Empathy
    43:28 Future of Empathy Training
    The Empathy Effect (Dr. Riess's book)
    The Power of Empathy (TEDx Talk)

    This discussion is for educational purposes and does not substitute for individual clinical judgment or patient care.

    Senior Producer: Jon Earle


    Obsessive-Compulsive Disorder (with Christopher Pittenger, MD, PhD) Feb 20, 2024
    Show notes

    Dr. Christopher Pittenger is a Professor of Psychiatry at the Yale School of Medicine and Director of the Yale OCD Research Clinic. In this episode, he discusses the neurobiology, symptomology, and treatment of Obsessive-Compulsive Disorder (OCD), including potential new treatments such as psychedelics, neurofeedback, glutamate modulators, and transcranial magnetic stimulation (TMS).
    00:00 Introduction
    00:41 Why is OCD Underdiagnosed?
    02:19 Impact of OCD on Individuals
    03:40 Taboo Nature of OCD Thoughts
    06:10 Biomarkers
    08:06 Neurobiology
    14:20 Serotonin
    16:48 Heterogeneity of OCD
    24:00 Glutamate Modulators
    29:33 Ketamine
    33:13 Psilocybin
    38:23 Neurofeedback
    44:01 Transcranial Magnetic Stimulation (TMS)
    47:22 Relationship Between Depression and OCD
    50:24 Future of OCD Treatment

    This discussion is for educational purposes and does not substitute for individual clinical judgment or patient care.

    Senior Producer: Jon Earle


    Meditation (with Richard Davidson, PhD) Feb 13, 2024
    Show notes

    Dr. Richard Davidson is the William James and Vilas Professor of Psychology and Psychiatry at the University of Wisconsin–Madison and Founder & Director of the Center for Healthy Minds. In this episode, he discusses the current state of research on mindfulness and meditation as mental health interventions.
    00:00 Introduction
    02:15 Focus areas in current research
    04:37 Well-being as a universal intervention
    06:21 Beyond mindfulness: other forms of meditation
    07:24 Four pillars of well-being: awareness, connection, insight, and purpose
    13:04 Healthy Minds Program and the impact of short daily meditation practices
    17:05 Comparison of Mindfulness-Based Stress Reduction (MBSR) and the Healthy Minds Program, focusing on accessibility and time commitment
    20:55 The potential for structural changes in the brain with meditation
    26:24 Integrating mindfulness and meditation into clinical practice
    28:06 Micro-supports for everyday well-being
    33:27 Mindfulness and social connection
    35:06 Future research directions, including the concept of a flourishing city

    This discussion is for educational purposes and does not substitute for individual clinical judgment or patient care.

    Senior Producer: Jon Earle


    Precision Psychiatry (with Ronald Kessler, PhD) Feb 06, 2024
    Show notes

    Dr. Ronald Kessler is the McNeil Family Professor of Health Care Policy at Harvard Medical School. His groundbreaking work on the social determinants of mental health, studied from an epidemiological perspective, has made him the most widely cited psychiatric researcher in the world. In this wide-ranging conversation, he talks about precision psychiatry's enormous potential and incremental development, delving into his own efforts to better identify at-risk patients and predict treatment efficacy. Dr. Kessler stresses the need for better data and bigger studies, and envisions a future of AI-supported clinicians.
    00:00 Introduction
    00:53 Dr. Kessler's Journey to Precision Psychiatry
    02:45 The Importance of Data
    04:14 Risk Factors and Treatment Optimization
    10:42 Successes and Challenges
    13:23 The Importance of Baseline Information
    23:46 Machine Learning in Veterans Health
    24:27 Determining Suicide Risk
    25:35 Interventions and Cost-Effectiveness
    26:16 Esketamine Trials and Response Prediction
    27:07 Risk Models and Comparative Risk Models
    27:15 Insomnia Treatment in Military Personnel
    29:36 Cost-Benefit Analyses
    35:45 AI in Medicine and Patient Response
    42:21 Future of Precision Psychiatry
    45:51 Closing Remarks

    This discussion is for educational purposes and does not substitute for individual clinical judgment or patient care.

    Senior Producer: Jon Earle


    Addiction (with Petros Levounis, MD, MA) Jan 30, 2024
    Show notes

    Dr. Petros Levounis is President of the American Psychiatric Association and a leader in addiction research. He joins host Thea Gallagher, PsyD, to talk about the latest in addiction medicine, the state of the opioid crisis, the growing problem of technology addiction, and the promise and risks of psychedelic medicine. He also shares his hopes for the future of psychiatry, including better integration of diagnoses, treatments, and outcomes for people with mental health disorders.
    00:00 Introduction to NYU Langone Insights on Psychiatry
    00:16 Dr. Levounis's role and priorities as APA president
    00:46 The State of Addiction Medicine
    02:12 Neurobiology of Addiction
    03:37 Interplay Between Mental Health and Addiction
    06:03 Potential and Challenges of Psychedelic Medicine
    08:37 Cannabis and Tech Addictions
    10:11 Addressing the Opioid Crisis: Strategies and Solutions
    15:28 Addressing Technological Addictions
    28:55 The Future of Psychiatry: Goals and Aspirations
    35:47 Conclusion and Final Thoughts

    This discussion is for educational purposes and does not substitute for individual clinical judgment or patient care.

    Senior Producer: Jon Earle


    Season 2 Announcement Oct 30, 2023
    Show notes

    Starting this fall, we're releasing 12 more conversations with the best minds in psychiatry. Subscribe wherever you're listening, so you won't miss an episode.

    This discussion is for educational purposes and does not substitute for individual clinical judgment or patient care.

    Senior Producer: Jon Earle


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