Neurology® Podcast

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Long-term outcome in neuroZika: When biological diagnosis matters May 20, 2019

Show notes

In the first segment, Dr. Stacey Clardy talks with Dr. Annie Lannuzel about the importance of biological diagnosis in long-term outcome in neuroZika. In the second part of the podcast, Dr. Will Rondeau focuses his interview with Dr. Stuart Connolly on his NEJM paper on the full study report of andexanet alfa for bleeding associated with factor Xa inhibitors. The paper can be found here: https://www.nejm.org/doi/full/10.1056/NEJMoa1814051.

CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

Developments and Scandals Related to Genetic Testing and Technology in Neurology (Delayed Recall May 2019) May 16, 2019

Show notes

This month's Delayed Recall highlights episodes on developments and scandals related to genetic testing and technology in neurology. Dr. Jason Crowell and Dr. Josephine Johnston of the Hastings Center start the show discussing the ethical and philosophical implications of gene editing., which first aired on December 18th, 2018. The next segment, also from December 18th, has Dr. Stacey Clardy and Dr. Stefan Pulst focusing on the scientific and societal impact of the recent first reported gene editing using the CRISPR technology. Following this segment is one from December 3rd and finds Dr. Jeff Waugh talking with Dr. Saadet Andrews about her paper on the genetic landscape of pediatric movement disorders and management implications. This episode continues with an interview on a Neurology: Genetics on the long journey to diagnosis for patients with mitochondrial disease between Dr. Jason Crowell and Drs. John L.P. Thompson and Michio Hirano from April 3rd, 2018. The episode wraps up with a talk between Dr. Jeffrey Ratliff and Dr. Thomas Bird from March 20th, 2018, on Dr. Bird's Neurology: Clinical Practice paper on the benefits and limitations of exome sequencing to identify hereditary ataxias.

Meta-analysis and cost-effectiveness of second-line antiepileptic drugs for status epilepticus May 13, 2019

Show notes

In the first segment, Dr. Lindsay Higdon talks with Dr. Ivan Sanchez Fernandez about his paper on the meta-analysis and cost-effectiveness of second-line antiepileptic drugs for status epilepticus. In the second part of the podcast, Dr. Stacey Clardy talks with Dr. Anthony Fauci about the measles outbreak of 2019. You can read the paper in NEJM: https://www.nejm.org/doi/full/10.1056/NEJMp1905099.

Practice guideline recommendations summary: The treatment of tics in people with Tourette syndrome and chronic tic disorders May 06, 2019

Show notes

In the first segment, Dr. Jeffrey Ratliff talks with Dr. Tamara Milka Pringsheim about her practice guideline recommendations summary paper on the treatment of tics in people with Tourette syndrome and chronic tic disorders. In the What's Trending segment, you'll hear the second part of an interview between Dr. Jason Crowell and New York Times staff writer Pam Belluck on CRISPR and gene editing.

Mouse model of anti-NMDA receptor post–herpes simplex encephalitis Apr 29, 2019

Show notes

In the first segment, Dr. Stacey Clardy talks with Dr. Jenny Linnoila about her March 2019 Neurology: Neuroimmunology & Neuroinflammation paper on a mouse model of anti-NMDA receptor post–herpes simplex encephalitis. In the second segment, Jason Crowell talks with Pam Belluck of the New York Times about He Jiankui, gene editing, and CRISPR.

Montreal Cognitive Assessment as a screening tool: Influence of performance and symptom validity Apr 22, 2019

Show notes

In the first segment, Dr. Gregory Day talks with Dr. Brigid Waldron-Perrine about her Neurology: Clinical Practice paper addressing the Montreal Cognitive Assessment as a screening tool. In the second part of the podcast, Dr. Jeffrey Burns focuses his interview with Dr. Mathias Jucker on how serum neurofilament dynamics predict neurodegeneration and clinical progression in presymptomatic Alzheimer's disease. The article can be found in Nature: https://www.nature.com/articles/s41591-018-0304-3.

Comparative effectiveness of teriflunomide and dimethyl fumarate. A nationwide cohort study Apr 16, 2019

Show notes

In the first segment, Dr. Stacey Clardy talks with Dr. Mathias Buron about his paper addressing the comparative effectiveness of teriflunomide and dimethyl fumarate. In the second part of the podcast, Dr. Jason Crowell focuses his interview with Dr. Joanna Hellmuth on the rise of pseudomedicine for dementia and brain health.

How much do periventricular lesions assist in distinguishing migraine with aura from CIS? Apr 08, 2019

Show notes

In the first segment, Dr. Stacey Clardy talks with Dr. Caterina Lapucci about her paper addressing how much periventricular lesions assist in distinguishing migraine with aura from CIS. In the second part of the podcast, Dr. Jason Crowell focuses his interview with Sarah Karlin-Smith and Sarah Owermohle from Politico on drug pricing.

Automated seizure detection accuracy for ambulatory EEG recordings Apr 01, 2019

Show notes

In the first segment, Dr. Derek Bauer talks with Dr. Stephan Schuele about his paper on automated seizure detection accuracy for ambulatory EEG recordings. In the second part of the podcast, Dr. Nicole Chiota-McCollum focuses her interview with Dr. Kevin Barrett on the SHINE stroke trial.

Practice Current: Autoimmune Encephalitis & the Role of Antibody Testing Mar 29, 2019

Show notes

Dr. Luca Bartolini discusses autoimmune encephalitis and the role of antibody testing based on a Practice Current survey run between November 2017 and May 2018.

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