Neurology Minute

Latest Episodes:

Investigating Whether Dissemination in Time Is Essential to Diagnose Relapsing MS Mar 07, 2025

Show notes

Dr. Alison Christy and Dr. Wallace J. Brownlee discuss whether dissemination in time is necessary to make a diagnosis of MS in patients who fulfill a high number of dissemination in space criteria.

Show reference:

https://www.neurology.org/doi/10.1212/WNL.0000000000210274

Overview from the 2025 International Stroke Conference - Part 2 Mar 06, 2025

Show notes

In part two of this two-part series, Dr. Andy Southerland and Dr. Seemant Chaturvedi discuss the PRESTIAGE-AF trial.

Show references:

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00333-2/fulltext

Overview from the 2025 International Stroke Conference - Part 1 Mar 05, 2025

Show notes

In part one of this two-part series, Dr. Andy Southerland and Dr. Seemant Chaturvedi discuss two trials that were looking at the use of endovascular therapy for medium vessel occlusion.

Show references:

https://www.nejm.org/doi/full/10.1056/NEJMoa2411668

https://www.nejm.org/doi/full/10.1056/NEJMoa2408954

Acquired Dystonia Mar 04, 2025

Show notes

Dr. Jeff Ratliff delves into the common causes of acquired dystonia and highlights evidence-based treatment strategies for effective management.

Orthostatic Tremor Mar 03, 2025

Show notes

Dr. Jeff Ratliff provides an in-depth look at orthostatic tremor, a rare and often overlooked movement disorder, highlighting its symptoms, challenges, and the importance of early detection.

Show references:

https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mdc3.13454

Exploring GLP-1 Receptor Agonists for Neurodegeneration - Part 2 Feb 28, 2025

Show notes

In part two of this two-part series, Dr. Vikram Karnik and Dr. Lorraine Kalia discuss the preclinical data and epidemiological data that led us to the phase three study on exenatide.

Show reference:

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00161-8/abstract

Exploring GLP-1 Receptor Agonists for Neurodegeneration - Part 1 Feb 27, 2025

Show notes

In part one of this two-part series, Dr. Vikram Karnik and Dr. Lorraine Kalia discuss recent clinical trials on exenatide as a disease-modifying therapy for Parkinson disease.

Show reference:

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00161-8/abstract

Vascular Risk Factor Burden Among Young Adults with Ischemic Stroke Feb 26, 2025

Show notes

Dr. BJ Hicks and Dr. Aaron Shoskes discuss the rising incidence of ischemic stroke in young adults.

Show references:

https://www.neurology.org/doi/10.1212/WNL.0000000000213447

First Drug Approved in New Class of Non-Opioid Pain Medicines Feb 25, 2025

Show notes

Dr. Tesha Monteith discusses Journavx (suzetrigine), a new medication for pain management.

Show references:

https://www.fda.gov/news-events/press-announcements/fda-approves-novel-non-opioid-treatment-moderate-severe-acute-pain