MTS is a live news and interview show covering technology, business, politics, and culture as it happens.
Welcome to the situation room.
https://x.com/MTSlive
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MTS is a live news and interview show covering technology, business, politics, and culture as it happens.
Welcome to the situation room.
https://x.com/MTSlive
Niko McCarty joins MTS to discuss hyperspectral biology, planetary scale biosensing, and the role of AI in synthetic biology. McCarty explains how hyperspectral cameras can detect engineered microbes and natural biological signatures from space, the work required to build large-scale molecular datasets, and why AI-designed biological systems may outpace mechanistic understanding.--https://x.com/NikoMcCarty--
MTS is a live news and interview show covering technology, business, politics, and culture as it happens.
Follow MTS:
X | ā https://twitter.com/MTSliveā
YouTube | ā https://www.youtube.com/@mtsituationā
Spotify | ā https://open.spotify.com/show/4HUNNmV1pjV7CW6Lphm1rMā
Apple | ā https://podcasts.apple.com/us/podcast/mts/id1891088763ā
Substack | ā https://mtslive.substack.com/ā
Interested in sponsoring the show? ā ā ā ā ā ā sponsors@mts.nowā ā
--
Brought to you by:
Neon (by Databricks) - Get up to $100K in credits for your startup at ā https://neon.com/mtsā
ElevenLabs - AI that communicates at human level across every channel and modality. https://elevenlabs.io/mts
Granola - The AI notepad. Try it once and never go back. https://granola.ai/mts
Kong - The AI connectivity platform. Connect APIs, LLMs, agents, and systems with serious security and governance. https://konghq.com
Blitzy - Autonomous software development for enterprise codebases. Ship 5x faster. https://blitzy.com
Merge - OpenAI, Dropbox, and Ramp use Merge to get AI to production faster. https://merge.dev/mts
AdQuick - Make your brand a billboard. Out-of-home advertising as easy to scale as digital. https://adquick.com
Macroscope - AI codebase understanding for engineering leaders. https://macroscope.com/mts
--
Timestamps:
(00:00) Introduction
(01:33) Defining Hyperspectral Biology
(04:23) Unlocking the Field
(06:42) Planetary Scale Biosensing
(11:46) Building the Datasets
(17:48) Solving the Spectrum Competition
(22:49) AI's Implications for Biology
(25:46) The Subfield of Interpretability
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Note: This podcast is not investment, legal, or tax advice, and is intended for informational and entertainment purposes only. Hosts and guests may hold positions in the companies and securities discussed; do your own research before acting on anything you hear.
Tim Hwang joins MTS to discuss legal advocacy in the judiciary, balancing power against state and lab monopolies, and how automated technologies could reshape the court system.
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MTS is a live news and interview show covering technology, business, politics, and culture as it happens.
Follow MTS:
X | ā https://twitter.com/MTSliveā
YouTube | ā https://www.youtube.com/@mtsituationā
Spotify | ā https://open.spotify.com/show/4HUNNmV1pjV7CW6Lphm1rMā
Apple | ā https://podcasts.apple.com/us/podcast/mts/id1891088763ā
Substack | ā https://mtslive.substack.com/ā
Interested in sponsoring the show? ā ā ā ā ā ā sponsors@mts.nowā ā
--
Brought to you by:
Neon (by Databricks) - Get up to $100K in credits for your startup at ā https://neon.com/mtsā
ElevenLabs - AI that communicates at human level across every channel and modality. https://elevenlabs.io/mts
Granola - The AI notepad. Try it once and never go back. https://granola.ai/mts
Kong - The AI connectivity platform. Connect APIs, LLMs, agents, and systems with serious security and governance. https://konghq.com
Blitzy - Autonomous software development for enterprise codebases. Ship 5x faster. https://blitzy.com
Merge - OpenAI, Dropbox, and Ramp use Merge to get AI to production faster. https://merge.dev/mts
AdQuick - Make your brand a billboard. Out-of-home advertising as easy to scale as digital. https://adquick.com
Macroscope - AI codebase understanding for engineering leaders. https://macroscope.com/mts
--
Timestamps:
(00:00) Introduction
(01:13) Explaining Frontier Legal Defense
(05:09) State Power And AI Risk
(07:58) Frontier Models Versus Weapons
(11:09) Copyright And Fair Use
(13:04) Educating The Judiciary
(21:42) The Future Of AI Judges
(26:24) AI And Rules Of Evidence
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Note: This podcast is not investment, legal, or tax advice, and is intended for informational and entertainment purposes only. Hosts and guests may hold positions in the companies and securities discussed; do your own research before acting on anything you hear.
FleetingBits joins MTS to discuss the Chinese AI ecosystem, forward deployed engineering at frontier labs, and the increasing role of government in AI development.
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MTS is a live news and interview show covering technology, business, politics, and culture as it happens.
Follow MTS:
X | ā https://twitter.com/MTSliveā
YouTube | ā https://www.youtube.com/@mtsituationā
Spotify | ā https://open.spotify.com/show/4HUNNmV1pjV7CW6Lphm1rMā
Apple | ā https://podcasts.apple.com/us/podcast/mts/id1891088763ā
Substack | ā https://mtslive.substack.com/ā
Interested in sponsoring the show? ā ā ā ā ā ā sponsors@mts.nowā ā
--
Brought to you by:
Neon (by Databricks) - Get up to $100K in credits for your startup at ā https://neon.com/mtsā
ElevenLabs - AI that communicates at human level across every channel and modality. https://elevenlabs.io/mts
Granola - The AI notepad. Try it once and never go back. https://granola.ai/mts
Kong - The AI connectivity platform. Connect APIs, LLMs, agents, and systems with serious security and governance. https://konghq.com
Blitzy - Autonomous software development for enterprise codebases. Ship 5x faster. https://blitzy.com
Merge - OpenAI, Dropbox, and Ramp use Merge to get AI to production faster. https://merge.dev/mts
AdQuick - Make your brand a billboard. Out-of-home advertising as easy to scale as digital. https://adquick.com
Macroscope - AI codebase understanding for engineering leaders. https://macroscope.com/mts
--
Timestamps:
(00:00) Introduction
(02:21) Understanding Chinese AI Character
(11:48) Insights From Lab Job Listings
(20:55) The OpenAI And Arm Partnership
(28:51) Philosophical Differences Between Labs
(31:34) Impact Of Government Export Controls
(39:57) The Future Of State Involvement
(48:07) Where To Follow Fleeting Bits
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Note: This podcast is not investment, legal, or tax advice, and is intended for informational and entertainment purposes only. Hosts and guests may hold positions in the companies and securities discussed; do your own research before acting on anything you hear.
Clement Delangue joins MTS to discuss why open source architecture inherently minimizes safety risks, the business validation of reaching 100 million dollars in annual recurring revenue, and how model routing will redistribute value away from dominant frontier labs.
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--
MTS is a live news and interview show covering technology, business, politics, and culture as it happens.
Follow MTS:
X | ā https://twitter.com/MTSliveā
YouTube | ā https://www.youtube.com/@mtsituationā
Spotify | ā https://open.spotify.com/show/4HUNNmV1pjV7CW6Lphm1rMā
Apple | ā https://podcasts.apple.com/us/podcast/mts/id1891088763ā
Substack | ā https://mtslive.substack.com/ā
Interested in sponsoring the show? ā ā ā ā ā ā sponsors@mts.nowā ā
--
Brought to you by:
Neon (by Databricks) - Get up to $100K in credits for your startup at ā https://neon.com/mtsā
ElevenLabs - AI that communicates at human level across every channel and modality. https://elevenlabs.io/mts
Granola - The AI notepad. Try it once and never go back. https://granola.ai/mts
Kong - The AI connectivity platform. Connect APIs, LLMs, agents, and systems with serious security and governance. https://konghq.com
Blitzy - Autonomous software development for enterprise codebases. Ship 5x faster. https://blitzy.com
Merge - OpenAI, Dropbox, and Ramp use Merge to get AI to production faster. https://merge.dev/mts
AdQuick - Make your brand a billboard. Out-of-home advertising as easy to scale as digital. https://adquick.com
Macroscope - AI codebase understanding for engineering leaders. https://macroscope.com/mts
--
Timestamps:
(00:00) Introduction
(01:13) Restricting Frontier Model Releases
(03:52) Regulating Open Source Models
(09:48) Scaling Open Source Platform Revenue
(11:02) Best Use Cases For Local Intelligence
(14:11) Geopolitics Of International Open Weights
(17:35) Advanced Capabilities Via Model Fusion
(21:13) Accusations Of Model Distillation Attacks
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Note: This podcast is not investment, legal, or tax advice, and is intended for informational and entertainment purposes only. Hosts and guests may hold positions in the companies and securities discussed; do your own research before acting on anything you hear.
Cremieux joins MTS to discuss the evolving development and massive popularity of GLP-1 weight loss drugs. He outlines a new AI-designed monoclonal antibody treatment for hair loss and explains how Chinese factories manufacture affordable peptides for the gray market.
Finally, Recueil details the retraction of a fraudulent lung cancer study and highlights the promising future of RAS inhibition in oncology-
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MTS is a live news and interview show covering technology, business, politics, and culture as it happens.
Follow MTS:
X | ā https://twitter.com/MTSliveā
YouTube | ā https://www.youtube.com/@mtsituationā
Spotify | ā https://open.spotify.com/show/4HUNNmV1pjV7CW6Lphm1rMā
Apple | ā https://podcasts.apple.com/us/podcast/mts/id1891088763ā
Substack | ā https://mtslive.substack.com/ā
Interested in sponsoring the show? ā ā ā ā ā ā sponsors@mts.nowā ā
--
Brought to you by:
Neon (by Databricks) - Get up to $100K in credits for your startup at ā https://neon.com/mtsā
ElevenLabs - AI that communicates at human level across every channel and modality. https://elevenlabs.io/mts
Granola - The AI notepad. Try it once and never go back. https://granola.ai/mts
Kong - The AI connectivity platform. Connect APIs, LLMs, agents, and systems with serious security and governance. https://konghq.com
Blitzy - Autonomous software development for enterprise codebases. Ship 5x faster. https://blitzy.com
Merge - OpenAI, Dropbox, and Ramp use Merge to get AI to production faster. https://merge.dev/mts
AdQuick - Make your brand a billboard. Out-of-home advertising as easy to scale as digital. https://adquick.com
Macroscope - AI codebase understanding for engineering leaders. https://macroscope.com/mts
--
Timestamps:
(00:00) Introduction
(01:40) People Are Very Slim
(05:18) Take Us Through The Arc Here
(10:07) Talk To Me About The New Hair Loss Drug
(18:18) Why Was It Retracted
(25:46) What Is On The Horizon Here
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Note: This podcast is not investment, legal, or tax advice, and is intended for informational and entertainment purposes only. Hosts and guests may hold positions in the companies and securities discussed; do your own research before acting on anything you hear.
Andrew Trask joins MTS to discuss how model fusion and automatic routing are shifting the AI industry from holistic products to a free market for intelligence.
He explains the expiration dates of public benchmarks, the role of encrypted inference in creating secure evaluations, and how data owners can safely monetize their information without losing control. Finally, he addresses the future of local client models and how individuals will bring value to a post-AI economy through specialized knowledge, taste, and trust networks.
MTS is a live news and interview show covering technology, business, politics, and culture as it happens.
Follow MTS:
X | ā https://twitter.com/MTSliveā
YouTube | ā https://www.youtube.com/@mtsituationā
Spotify | ā https://open.spotify.com/show/4HUNNmV1pjV7CW6Lphm1rMā
Apple | ā https://podcasts.apple.com/us/podcast/mts/id1891088763ā
Substack | ā https://mtslive.substack.com/ā
Interested in sponsoring the show? ā ā ā ā ā ā sponsors@mts.nowā ā
--
Brought to you by:
Neon (by Databricks) - Get up to $100K in credits for your startup at ā https://neon.com/mtsā
ElevenLabs - AI that communicates at human level across every channel and modality. https://elevenlabs.io/mts
Granola - The AI notepad. Try it once and never go back. https://granola.ai/mts
Kong - The AI connectivity platform. Connect APIs, LLMs, agents, and systems with serious security and governance. https://konghq.com
Blitzy - Autonomous software development for enterprise codebases. Ship 5x faster. https://blitzy.com
Merge - OpenAI, Dropbox, and Ramp use Merge to get AI to production faster. https://merge.dev/mts
AdQuick - Make your brand a billboard. Out-of-home advertising as easy to scale as digital. https://adquick.com
Macroscope - AI codebase understanding for engineering leaders. https://macroscope.com/mts
--
Timestamps:
(00:00) Preview + Introduction
(01:13) How Model Fusion Beats Individual Models
(04:07) Automatic Routing and Fleets of Capability
(06:45) JCR Licklider and the Final Form of the Internet
(11:13) Scaling Laws and the Shift to Local Models
(16:49) Monetizing Rare Knowledge, Taste, and Trust
(19:03) Fixing the Flaws of Public AI Benchmarks
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Note: This podcast is not investment, legal, or tax advice, and is intended for informational and entertainment purposes only. Hosts and guests may hold positions in the companies and securities discussed; do your own research before acting on anything you hear.
Max Marchione joins MTS to discuss the psychological and social effects of GLP-1 medications, the future of low-cost preventative scanning technology, and how childhood environmental exposure influences the modern prevalence of allergies.
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MTS is a live news and interview show covering technology, business, politics, and culture as it happens.
Follow MTS:
X | ā https://twitter.com/MTSliveā
YouTube | ā https://www.youtube.com/@mtsituationā
Spotify | ā https://open.spotify.com/show/4HUNNmV1pjV7CW6Lphm1rMā
Apple | ā https://podcasts.apple.com/us/podcast/mts/id1891088763ā
Substack | ā https://mtslive.substack.com/ā
Interested in sponsoring the show? ā ā ā ā ā ā sponsors@mts.nowā ā
--
Brought to you by:
Neon (by Databricks) - Get up to $100K in credits for your startup at ā https://neon.com/mtsā
ElevenLabs - AI that communicates at human level across every channel and modality. https://elevenlabs.io/mts
Granola - The AI notepad. Try it once and never go back. https://granola.ai/mts
Kong - The AI connectivity platform. Connect APIs, LLMs, agents, and systems with serious security and governance. https://konghq.com
Blitzy - Autonomous software development for enterprise codebases. Ship 5x faster. https://blitzy.com
Merge - OpenAI, Dropbox, and Ramp use Merge to get AI to production faster. https://merge.dev/mts
AdQuick - Make your brand a billboard. Out-of-home advertising as easy to scale as digital. https://adquick.com
Macroscope - AI codebase understanding for engineering leaders. https://macroscope.com/mts
--
Timestamps:
(00:00) Introduction
(01:25) Stripe Curing Respiratory Illness
(05:20) Childhood Environment and Allergies
(07:13) GLP-1 Impact on Romance
(12:33) Optimal Long Term Dosing
(14:45) Reshaping Healthcare With Scanners
(21:34) Next Human Enhancement Drug
(26:03) Future Bets on Biology
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Note: This podcast is not investment, legal, or tax advice, and is intended for informational and entertainment purposes only. Hosts and guests may hold positions in the companies and securities discussed; do your own research before acting on anything you hear.
Zack Shapiro joins MTS to discuss how AI is disrupting Big Law's traditional business models. He explains why building internal software beats renting generic tools and details the regulatory barriers stopping tech labs from buying law firms outright. Finally, he shares his exact framework for training attorneys to convert manual cognitive work into custom, automated AI workflows.
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--
MTS is a live news and interview show covering technology, business, politics, and culture as it happens.
Follow MTS:
X | ā https://twitter.com/MTSliveā
YouTube | ā https://www.youtube.com/@mtsituationā
Spotify | ā https://open.spotify.com/show/4HUNNmV1pjV7CW6Lphm1rMā
Apple | ā https://podcasts.apple.com/us/podcast/mts/id1891088763ā
Substack | ā https://mtslive.substack.com/ā
Interested in sponsoring the show? ā ā ā ā ā ā sponsors@mts.nowā ā
--
Brought to you by:
Neon (by Databricks) - Get up to $100K in credits for your startup at ā https://neon.com/mtsā
ElevenLabs - AI that communicates at human level across every channel and modality. https://elevenlabs.io/mts
Granola - The AI notepad. Try it once and never go back. https://granola.ai/mts
Kong - The AI connectivity platform. Connect APIs, LLMs, agents, and systems with serious security and governance. https://konghq.com
Blitzy - Autonomous software development for enterprise codebases. Ship 5x faster. https://blitzy.com
Merge - OpenAI, Dropbox, and Ramp use Merge to get AI to production faster. https://merge.dev/mts
AdQuick - Make your brand a billboard. Out-of-home advertising as easy to scale as digital. https://adquick.com
Macroscope - AI codebase understanding for engineering leaders. https://macroscope.com/mts
--
Timestamps:
(00:35) Introduction
(01:14) The Kirkland & Ellis AI Initiative
(02:14) Billable Hours and The Innovator's Dilemma
(06:44) Shifting to Value-Based Models
(07:42) The Enterprise Diffusion Gap
(09:08) Why Tech Labs Don't Buy Law Firms
(11:53) Practicing as a Claude Native Law Firm
(13:34) Redefining Prompting Strategy
--
Note: This podcast is not investment, legal, or tax advice, and is intended for informational and entertainment purposes only. Hosts and guests may hold positions in the companies and securities discussed; do your own research before acting on anything you hear.
Marco Palladino joins MTS to discuss the rising agentic economy, the bifurcation of a human versus agent-facing internet, and how engineering autonomous loops is replacing manual prompt writing. --https://x.com/subnetmarco--
MTS is a live news and interview show covering technology, business, politics, and culture as it happens.
Follow MTS:
X | ā https://twitter.com/MTSliveā
YouTube | ā https://www.youtube.com/@mtsituationā
Spotify | ā https://open.spotify.com/show/4HUNNmV1pjV7CW6Lphm1rMā
Apple | ā https://podcasts.apple.com/us/podcast/mts/id1891088763ā
Substack | ā https://mtslive.substack.com/ā
Interested in sponsoring the show? ā ā ā ā ā ā sponsors@mts.nowā ā
--
Brought to you by:
Neon (by Databricks) - Get up to $100K in credits for your startup at ā https://neon.com/mtsā
ElevenLabs - AI that communicates at human level across every channel and modality. https://elevenlabs.io/mts
Granola - The AI notepad. Try it once and never go back. https://granola.ai/mts
Kong - The AI connectivity platform. Connect APIs, LLMs, agents, and systems with serious security and governance. https://konghq.com
Blitzy - Autonomous software development for enterprise codebases. Ship 5x faster. https://blitzy.com
Merge - OpenAI, Dropbox, and Ramp use Merge to get AI to production faster. https://merge.dev/mts
AdQuick - Make your brand a billboard. Out-of-home advertising as easy to scale as digital. https://adquick.com
Macroscope - AI codebase understanding for engineering leaders. https://macroscope.com/mts
--
Timestamps:
(00:00) Introduction
(01:03) What Does Handling Loops Mean
(03:15) How Is Kong Using Agents
(08:41) What Does Agentic Architecture Look Like
(09:58) Biggest Non-Technical AI Blockers
(16:24) Future of the Software Economy
(20:04) Has the Internet Already Split
(23:57) Will Model Capabilities Enable Agents
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Note: This podcast is not investment, legal, or tax advice, and is intended for informational and entertainment purposes only. Hosts and guests may hold positions in the companies and securities discussed; do your own research before acting on anything you hear.
Jake Fitzgerald joins MTS to discuss generative CAD for robotics, spatial reasoning improvements in frontier models, and resources for learning hardware design.
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MTS is a live news and interview show covering technology, business, politics, and culture as it happens.
Follow MTS:
X | ā https://twitter.com/MTSliveā
YouTube | ā https://www.youtube.com/@mtsituationā
Spotify | ā https://open.spotify.com/show/4HUNNmV1pjV7CW6Lphm1rMā
Apple | ā https://podcasts.apple.com/us/podcast/mts/id1891088763ā
Substack | ā https://mtslive.substack.com/ā
Interested in sponsoring the show? ā ā ā ā ā ā sponsors@mts.nowā ā
--
Brought to you by:
Neon (by Databricks) - Get up to $100K in credits for your startup at ā https://neon.com/mtsā
ElevenLabs - AI that communicates at human level across every channel and modality. https://elevenlabs.io/mts
Granola - The AI notepad. Try it once and never go back. https://granola.ai/mts
Kong - The AI connectivity platform. Connect APIs, LLMs, agents, and systems with serious security and governance. https://konghq.com
Blitzy - Autonomous software development for enterprise codebases. Ship 5x faster. https://blitzy.com
Merge - OpenAI, Dropbox, and Ramp use Merge to get AI to production faster. https://merge.dev/mts
AdQuick - Make your brand a billboard. Out-of-home advertising as easy to scale as digital. https://adquick.com
Macroscope - AI codebase understanding for engineering leaders. https://macroscope.com/mts
--
Timestamps:
(00:00) Introduction
(00:01) Journey Back to Robotics
(00:03) Frustrations With 3D CAD
(00:04) Spatial Reasoning Breakthroughs
(00:08) Humanoid Autonomy Timelines
(00:11) Best Resources For Robotics
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Note: This podcast is not investment, legal, or tax advice, and is intended for informational and entertainment purposes only. Hosts and guests may hold positions in the companies and securities discussed; do your own research before acting on anything you hear.