TopPodcast.com
Menu
  • Home
  • Top Charts
  • Top Networks
  • Top Apps
  • Top Independents
  • Top Podfluencers
  • Top Picks
    • Top Business Podcasts
    • Top True Crime Podcasts
    • Top Finance Podcasts
    • Top Comedy Podcasts
    • Top Music Podcasts
    • Top Womens Podcasts
    • Top Kids Podcasts
    • Top Sports Podcasts
    • Top News Podcasts
    • Top Tech Podcasts
    • Top Crypto Podcasts
    • Top Entrepreneurial Podcasts
    • Top Fantasy Sports Podcasts
    • Top Political Podcasts
    • Top Science Podcasts
    • Top Self Help Podcasts
    • Top Sports Betting Podcasts
    • Top Stocks Podcasts
  • Podcast News
  • About Us
  • Podcast Advertising
  • Contact
Not in our directory?
Add Show Here
Podcast Equipment
Center

toppodcastlogoOur TOPPODCAST Picks

  • Comedy
  • Crypto
  • Sports
  • News
  • Politics
  • True Crime
  • Business
  • Finance

Follow Us

toppodcastlogoStay Connected

    View Top 200 Chart
    Back to Rankings Page
    Science

    Mind & Matter

    Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists & thinkers alive today about how your mind-body reacts to what you feed it.

    The weekly M&M podcast features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today.

    Not medical advice.

    At M&M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so be it.

    As the host, my aim is to help you better understand how the body & mind work by curating & synthesizing information in a way that yields science-based insights that you can choose to use or disregard in your own life. Taking ownership of your health starts with taking ownership of your information diet.

    I am motivated to connect the dots and distill general principles from what I learn, preferring to ask questions and play devil’s advocate to debating or incessantly pushing my own viewpoint.

    My beliefs:

    • Taking ownership of your health starts with taking ownership of your information diet.
    • All knowledge is provisional and we must work hard to prevent ourselves from becoming attached to our favorite ideas & preferred conclusions.
    • Wisdom comes from an iterative, trial-and-error process of learning and unlearning. Letting go of pre-conceived notions can be painful, but pain is information.

    Sometimes modern discoveries teach us we must unlearn received wisdom. Other times, modern information overload & historical chauvinism cause us to forget ancient wisdom which stills applies. The framework for learning that I embody is inspired by three Ancient Greek maxims inscribed in the Temple of Apollo at Delphi:

    • “Γνῶθι σεαυτόν” (Know thyself)
    • “Μηδὲν ἄγαν” (Nothing in excess)
    • “Ἐγγύα πάρα δ Ἄτα” (Certainty brings insanity)
    Advertise

    Copyright: © 2025 Nick Jikomes

    • Apple Podcasts
    • Google Play
    • Spotify

    Latest Episodes:
    Systems Thinking, Organizational Structures, Building Startups, Remote Work & Control vs. Enablement | Alexandros Marinos | 51 Dec 29, 2021
    Show notes

    Send us Fan Mail

    Nick talks to Alexandros Marinos, PhD, founder & CEO of the edge computing technology startup, Balena. They discuss the internal organization of complex human systems.
    Alex talked about how he thinks about the organizational structure of his own company and how organizational structures impact group dynamics, growth, conflicts of interest, and innovation. One interesting area Alex provided commentary and analysis on towards the end is how to make sense of the behavior of large institutional organizations, such as the Centers for Disease Control (CDC).

    If you’re interested in complex systems like human organizations, how the internal structures of different organizations influence what they do and how they behave, and why human organizations can sometimes behave in deranged ways, this episode will be of interest to you.

    *Not medical advice.


    Support the show

    Support my work:

    • Good Chemistry: Personalized, science-based health consulting. Work with Dr. Nick Jikomes directly.
    • Affiliate Partners: Visit this link to see my affiliate partners and get discounts codes for products & services to support health.

    For all the ways you can support my efforts.


    Medical Glass, Materials Science & the COVID Vaccine Supply Chain | Chris Weikart | 50 Dec 22, 2021
    Show notes

    Send us Fan Mail

    Nick Jikomes talks to materials scientist Dr. Chris Weikart, who is currently chief scientist at SiO2, an advanced materials science company that combines chemistry and engineering to create containers and surfaces for use by biotechnology, genomics, diagnostics, and consumer products companies.

    They discuss how SiO2 created a new kind of vaccine vial, which combines both glass and plastic that are superior for storing and transporting biologics, such as vaccines. SiO2 is currently producing an enormous number of these vials for Moderna’s mRNA vaccines for COVID-19. Chris described how the vials are made, and what they’re made of, as well as what materials science is and how important it is to society. This conversation also gives you a sense of different parts of the COVID-19 vaccine supply chain and how they fit together.

    *Not medical advice.


    Support the show

    Support my work:

    • Good Chemistry: Personalized, science-based health consulting. Work with Dr. Nick Jikomes directly.
    • Affiliate Partners: Visit this link to see my affiliate partners and get discounts codes for products & services to support health.

    For all the ways you can support my efforts.


    Does Adolescent Marijuana (Cannabis) Use Cause Psychosis? | Jonathan Schaefer | 49 Dec 15, 2021
    Show notes

    Send us Fan Mail

    Nick talks to Dr. Jonathan Schaefer about the link between adolescent cannabis (marijuana) use and psychosis.
    Jonathan has a PhD in clinical psychology and he is currently a research psychologist at the University of Minnesota Institute of Child Development. His research focuses largely on the relationship between people’s environments that influence their mental health. He has conducted a number of longitudinal studies using cohorts of identical and fraternal twins, which allow him to tease apart the role of genetic vs. environmental factors in different psychiatric outcomes.

    The conversation focuses mainly on recent twin studies Dr. Schaefer has done looking at the relationship between adolescent cannabis (i.e. marijuana) use, and psychosis. They talk about what psychosis is and what factors are linked to it, historical work on the relationship between cannabis use and psychosis, and the results of Jonathan's recent twin studies & what they mean.

    *Not medical advice.


    Support the show

    Support my work:

    • Good Chemistry: Personalized, science-based health consulting. Work with Dr. Nick Jikomes directly.
    • Affiliate Partners: Visit this link to see my affiliate partners and get discounts codes for products & services to support health.

    For all the ways you can support my efforts.


    Autism, the Cerebellum, Learning, Brain Development | Sam Wang | Episode 48 Dec 08, 2021
    Show notes

    Send us Fan Mail

    Nick Jikomes talks to Sam Wang, PhD professor of neuroscience at Princeton University. Dr. Wong’s lab investigates how brains learn from sensory experience, in adulthood and development, with relevance for autism. A lot of their work focuses on a part of the brain called the cerebellum.
    They talk about the cerebellum and what we’re learning about its functions, as well as how it’s tied to autism, and what the causes and nature of autism actually are. This included both the genetic and environmental risk factors for autism, and how to think about treatment. Lastly, they talk about another side of his work, which is related to using data and science to help repair our democracy by combatting things like congressional gerrymandering.
    *Not medical advice

    Support the show

    Support my work:

    • Good Chemistry: Personalized, science-based health consulting. Work with Dr. Nick Jikomes directly.
    • Affiliate Partners: Visit this link to see my affiliate partners and get discounts codes for products & services to support health.

    For all the ways you can support my efforts.


    Metabolism, Blood Sugar, Diabetes, Microbiome, Diet, Aging, Digital Phenotyping & Personalized Medicine | Nathan Price | Episode 47 Dec 01, 2021
    Show notes

    Send us Fan Mail

    Nick Jikomes talks to Dr. Nathan Price, who has a Ph.D. in bioengineering and has been faculty at the University of Washington and the Institute of Systems Biology. He was also CEO of a health intelligence startup called Onegevity, which recently merged with Thorne HealthTech, where he is the Chief Science Officer.
    Nathan and Nick discussed various topics in personalized medicine, digital phenotyping, and systems biology, including metabolism and blood sugar monitoring, the microbiome and diet, aging and longevity, and more. They discussed the basic biology of these things as well as different emerging technologies related to health monitoring.

    *Not medical advice.


    Support the show

    Support my work:

    • Good Chemistry: Personalized, science-based health consulting. Work with Dr. Nick Jikomes directly.
    • Affiliate Partners: Visit this link to see my affiliate partners and get discounts codes for products & services to support health.

    For all the ways you can support my efforts.


    Psychedelics, Psychoplastogens, Microdosing, Brain Chemistry, Mental Health, Novel Drugs | David Olson | Episode 46 Nov 23, 2021
    Show notes

    Send us Fan Mail

    Nick Jikomes talks to medicinal chemist Dr. David Olson whose lab at the University of California-Davis studies a class of compounds called ‘psychoplastogens,’ which are small molecules capable of promoting neural plasticity. His lab is on the cutting edge when it comes to understanding the mechanisms by which psychedelics and other psychoactive drugs work in the brain. They touch on: latest research from his lab, new tools they're developing and using to understand these drugs, whether it’s likely that we'll be able to produce non-hallucinogenic drug variants of classic psychedelics, and microdosing.
    *Not medical advice.

    Support the show

    Support my work:

    • Good Chemistry: Personalized, science-based health consulting. Work with Dr. Nick Jikomes directly.
    • Affiliate Partners: Visit this link to see my affiliate partners and get discounts codes for products & services to support health.

    For all the ways you can support my efforts.


    The Mystery of SARS-CoV-2 & Origins of COVID-19 | Alina Chan | Episode 45 Nov 15, 2021
    Show notes

    Send us Fan Mail

    Nick Jikomes talks to genetic engineer Dr. Alina Chan about the origins of the SARS-CoV-2 virus responsible for the COVID-19 pandemic. They discuss Alina's new book, "Viral: The Search For the Origin of COVID-19," which she co-wrote with Matt Ridley. The book thoroughly documents the events & people relevant to COVID's origins. They discuss everything from the original SARS-1 epidemic in China, wildlife spillover vs. accidental lab leak hypotheses; pangolins, bats, and other animals; SARS-CoV-2 genome; institutions and people like Francis Collins, the NIH, WHO, and EcoHealth Alliance.


    *Not medical advice.


    Support the show

    Support my work:

    • Good Chemistry: Personalized, science-based health consulting. Work with Dr. Nick Jikomes directly.
    • Affiliate Partners: Visit this link to see my affiliate partners and get discounts codes for products & services to support health.

    For all the ways you can support my efforts.


    Consciousness, Perception, Hallucinations, Selfhood, Neuroscience, Psychedelics & "Being You" | Anil Seth | Episode 44 Nov 10, 2021
    Show notes

    Send us Fan Mail

    Nick talks with Dr. Anil Seth, a neuroscientist and professor of cognitive & computational neuroscience at the University of Sussex. The conversation is all about the neuroscience of consciousness, which is the subject of his Dr. Seth's book, “Being You: A New Science of Consciousness.“

    They touch on everything from what consciousness actually is, whether or not neuroscientists can measure different levels of consciousness in the brain, what characterizes psychedelic experiences and non-ordinary states of consciousness in terms of the brain, and the nature of perception. In particular, they discuss ideas related to the notion that our conscious perceptions are a kind of inference, or guess, our brain’s are making about the world, as well as the idea that all of our conscious perceptions are "controlled hallucinations."
    They also discuss: exteroception (perceiving things outside the body, like objects); interoception (perceiving things within the body); and emotion. Lastly, Nick gets Anil’s take on whether consciousness is an evolutionary adaptation and psychedelics.
    *Not medical advice.

    Support the show

    Support my work:

    • Good Chemistry: Personalized, science-based health consulting. Work with Dr. Nick Jikomes directly.
    • Affiliate Partners: Visit this link to see my affiliate partners and get discounts codes for products & services to support health.

    For all the ways you can support my efforts.


    Sleep, Dreaming, Deep Neural Networks, Machine Learning & Artificial Intelligence, Overfitted Brain Hypothesis, Evolution of Fiction & Art | Erik Hoel | Episode 43 Nov 04, 2021
    Show notes

    Send us Fan Mail

    Nick talks to neuroscientist and writer Dr. Erik Hoel. Erik is a professor of biology at Tufts University. He received his PhD in neuroscience from the University of Wisconsin, where he studied under the sleep and consciousness researcher, Giulio Tononi. He did postdoctoral work at Columbia University, where he used information theory and other analytical tools to explore the biological basis of consciousness. He has come up with the so-called Overfitted Brain Hypothesis of dreaming, which explains the potential adaptive function of dreams by drawing analogies to techniques used to train Deep Neural Networks in the world of machine learning.

    Erik and Nick discuss the biology and phenomenology of dreams and sleep generally, including some of the various theories for why we sleep. They also discuss Deep Learning (on a very basic level) and Erik described the Overfitted Brain Hypothesis of dreaming. They also discuss fiction and the arts, including Erik’s new novel and the potential evolutionary reasons for why humans create and consume fiction, as well as some technology-driven developments that are reshaping how we create and consume written work online.
    *Not medical advice.


    Support the show

    Support my work:

    • Good Chemistry: Personalized, science-based health consulting. Work with Dr. Nick Jikomes directly.
    • Affiliate Partners: Visit this link to see my affiliate partners and get discounts codes for products & services to support health.

    For all the ways you can support my efforts.


    THC, CBD, Omega-3 Fatty Acids, L-Theanine, Opioids, Pregnancy, Brain Development, Addiction, Anxiety & Schizophrenia | Steve Laviolette | Episode 42 Oct 27, 2021
    Show notes

    Send us Fan Mail

    Nick Jikomes talks to Dr. Steven Laviolette, a neuroscientist at the University of Western Ontario. They discuss how different types of drugs impact emotion, cognition, brain development and the development of psychiatric conditions (e.g. addition, schizophrenia); drug interactions (THC + CBD, THC + L-Theanine, CBD + Omega-3 Fatty Acids), how drugs can affect brain development when consumed during adolescence, or by pregnant women; how cannabinoids interact with opioids in different ways.

    *Not medical advice.

    Support the show

    Support my work:

    • Good Chemistry: Personalized, science-based health consulting. Work with Dr. Nick Jikomes directly.
    • Affiliate Partners: Visit this link to see my affiliate partners and get discounts codes for products & services to support health.

    For all the ways you can support my efforts.


    Previous 1 25 26 27 28 29 32 Next

    Related Podcasts

    Invisibilia

    1

    Invisibilia Personal Journals
    Hidden Brain – Hidden Brain, Shankar Vedantam

    2

    Hidden Brain – Hidden Brain, Shankar Vedantam Science
    How To Do Everything

    3

    How To Do Everything Science
    Hidden Brain

    4

    Hidden Brain Games & Hobbies
    Something You Should Know

    5

    Something You Should Know Education
    Sword and Scale – Sword and Scale

    6

    Sword and Scale – Sword and Scale Alternative Health
    footer-logo

    Contact Us

    Toll Free: 844-670-7747

    Links

    • Home
    • Top Charts
    • Networks
    • Apps
    • Independents Podcasts
    • Podcast Advertising
    • Podcast News
    • Contact Us
    • About Us
    • Analytics & Insights

    Stay Connected

      Privacy, Terms of Use & Our Code of Ethics Protecting Content Creators Copyrights