MeSsy with Christina Applegate & Jamie Lynn Sigler

Latest Episodes:

Carl Radke Mar 17, 2026

Show notes

This week, Christina and Jamie are joined by Carl Radke, Summer House cast member and host of "More Life with Carl Radke.” They discuss his journey to sobriety, holding in shame, forgiveness, behind-the-scenes of the show, and more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Audio Engineer: Josh Windisch

This episode is sponsored by:

Wildgrain - Wildgrain is offering our listeners $30 off your first box - PLUS free Croissants for life - when you go to https://Wildgrain.com/MESSYto start your subscription today.

Fatty15- Get an additional 15% off their 90-day subscription Starter Kit by going to https://fatty15.com/messyand using code MESSY at checkout.

Jones Road - Use code MESSY at https://jonesroadbeauty.com to get a Free Shimmer Face Oil with your first purchase! #JonesRoadBeauty #ad

Lola Blankets - Get 40% off select Lola Blankets products at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

How to Heal Your Relationship With Life Mar 10, 2026

Show notes

This week, Christina and Jamie are joined by Jamie’s friend Ryan Weiss. They discuss how he helped her through a difficult time, the power of dance, emotional avoidance, why it’s so hard to look inward, and more.

Check out Ryan's course "How to Be Okay When Things Are Not Okay" and use code MESSY at checkout for 10% off

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Audio Engineer: Josh Windisch

This episode is sponsored by:

Lola- Get 40% off select Lola Blankets products at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.

Zoc Doc - Stop putting off those doctors appointments and go to https://Zocdoc.com/MESSY to find and instantly book a doctor you love today.

One Skin - Get 15% off OneSkin with the code MESSY at https://www.oneskin.co/MESSY #oneskinpod

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

We Don’t Want to Be Defined by This Mar 03, 2026

Show notes

This week, Christina and Jamie read listener emails and discuss the fragility of life, fighting against your body, and more,

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Audio Engineer: Josh Windisch

This episode is sponsored by:

Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/MESSY #honeylovepod

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Kelly Ripa Feb 24, 2026

Show notes

This week, Christina and Jamie are joined by their friend Kelly Ripa. They discuss Kelly's career and how it began at a toy fair, the processing she had to do while writing her own book, the challenges of playing yourself on television, and much more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Audio Engineer: Josh Windisch

This episode is sponsored by:

Fatty15 - Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/MESSY and using code MESSY at checkout.

Lola - Get 40% off select Lola Blankets products at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.

AG1 - For a limited time only, go to https://DRINKAG1.com/MESSYto get a FREE AG1 Flavor Sampler and AGZ Sampler to try all the flavors, plus FREE Vitamin D3+K2 and AG1 Welcome Kit with your first AG1 subscription order!

Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Stop Talking About It for a Minute Feb 17, 2026

Show notes

This week, Christina and Jamie read listener emails and discuss skincare products from childhood, crazy animal stories, not thinking too far into the future, and much more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Audio Engineer: Josh Windisch

This episode is sponsored by:

Wildgrain - Wildgrain is offering our listeners $30 off your first box - PLUS free Croissants for life - when you go to Wildgrain.com/MESSY to start your subscription today.

Jones Road - Use code messy at https://jonesroadbeauty.com to get a Free Shimmer Face Oil with your first purchase! #JonesRoadBeauty #ad
Arey - Slow the growth of greys and get 15% off by using code MESSY at https://Arey.com

Cheers - Same night out — way better morning with Cheers. For a limited time our listeners are getting 20% off their entire order by using code MESSY at https://CheersHealth.com #Cheers #ad

ZocDoc - Stop putting off those doctors appointments and go to https://Zocdoc.com/MESSY to find and instantly book a doctor you love today.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

How You Feel on the Inside Can Be Up to You Feb 10, 2026

Show notes

This week, Christina and Jamie read listener emails and discuss the Married... with Children reunion, catch up on their TV shows, Jamie opens up about a recent experience, and more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Audio Engineer: Josh Windisch

This episode is sponsored by:

Veracity - For up to 45% off your order, head to https://VeracityHealth.co and use code MESSY

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

I Can't Worry About Tomorrow Feb 03, 2026

Show notes

This week, Christina and Jamie read listener emails and discuss MS fatigue, finding little moments of self care, how to better communicate with friends, and more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Audio Engineer: Josh Windisch

This episode is sponsored by:

Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod

Jones Road - Use code messy at https://jonesroadbeauty.com to get a Free Shimmer Face Oil with your first purchase! #JonesRoadBeauty #ad

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Bobbi Brown Jan 27, 2026

Show notes

This week, Christina and Jamie are joined by Bobbi Brown. They discuss overcoming obstacles, how to elevate your mood, taking baby steps, and much more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Audio Engineer: Josh Windisch

This episode is sponsored by:

Lola - Get 40% off your entire order at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.

AG1 - Go to https://DRINKAG1.com/MESSYto get their best offer… get a FREE AG1 Flavor Sampler and AGZ Sampler to try all the flavors, plus FREE Vitamin D3+K2 and AG1 Welcome Kit with your first AG1 subscription order!

Warby Parker - MeSsy listeners get 15% off plus free shipping when they buy two or more pairs of prescription glasses at https://WarbyParker.com /MESSY— using our link helps support the show. #WarbyParker #ad

Fatty15 - Fatty15 is on a mission to optimize your C15 levels to help support your long-term health and wellness -Get an additional 15% off their 90-day subscription Starter Kit at fatty15.com/MESSYand using code MESSY at checkout.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

I’m a F**king Warrior Jan 20, 2026

Show notes

This week, Christina and Jamie read listener emails and discuss Jamie’s recent trip, pregnancy and MS, asking for help, and more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Audio Engineer: Josh Windisch

This episode is sponsored by:

Wildgrain - Wildgrain is offering our listeners $30 off your first box - PLUS free Croissants for life - when you go to Wildgrain.com/MESSY to start your subscription today.

Veracity - For up to 45% off your order, head to https://VeracityHealth.co and use code MESSY

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The Impact of Inflammation with Dr. Will Cole Jan 13, 2026

Show notes

This week, Christina and Jamie are joined by Dr. Will Cole, a functional medicine expert. They discuss how to calm inflammation, medical gaslighting, the interactions between all our systems, and much more.

Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Audio Engineer: Josh Windisch

This episode is sponsored by:

MudWtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code MESSY at https://mudwtr.com/messy #mudwtrpod

Grow TherapyWhatever challenges you’re facing, Grow Therapy is here to help. Sessions average about $21 with insurance and some pay as little as $0, depending on their plan. Visit https://GrowTherapy.com/MESSY today to get started.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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