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Literally! With Rob Lowe — Society & Culture
Literally! With Rob Lowe

This is literally a podcast where people I love, admire, and know well will be in a safe space to really let their hair down (assuming they have any). I will cover the thoughtful to the extremely random. So join me and my guests from the world of movies, TV, sports, music, and culture for fun, wide-ranging, free-wheeling conversations.

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Latest Episodes:

Spiritual Medium Rebecca Rosen talks to Rob Lowe (Re-Release) Oct 29, 2026

Show notes

We're looking back at Rob's conversation with internationally renowned spiritual medium Rebecca Rosen. Hear Rebecca and Rob talk about the logical versus intuitive mind, Rebecca’s journey into her unique career, and the power of dreaming in Rob’s life. This episode originally aired in 2023. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Danny Elfman: The Chili Pepper Thing (Re-Release) Oct 26, 2026

Show notes

It's almost Halloween, so we're looking back at Rob's conversation with "The Nightmare Before Christmas" composer and Oingo Boingo frontman Danny Elfman! The legendary musician joins Rob Lowe to discuss why the theme from Halloween drove Danny wild, what it took to squash the beef between him and Simpsons creator Matt Groening, and which funk-rock band used to get booed while opening for Oingo Boingo. This episode originally aired in 2021. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Ed Helms: Benevolent Fan of Flannel (Re-Release) Oct 22, 2026

Show notes

We're looking back at Rob's conversation with "The Office" and "The Hangover" star Ed Helms! Find out about Ed's podcast SNAFU, which Hangover star does the best Christopher Walken impression, and how Ace Ventura 2 helped him pass the time while filming The Office. This episode originally aired in 2022. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

David Duchovny: Malibu Bicycle Cops (Re-Release) Oct 15, 2026

Show notes

We're looking back at Rob's conversation with the great David Duchovny! Rob and David discuss conspiracy theories, David’s albums and novels, minimalism, the danger of doing your own stunts, and their time together on Californication. This episode originally aired in 2021. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Introducing: We Got Company with Sebastian Maniscalco Oct 13, 2026

Show notes

Comedian, actor and writer Robby Hoffman joins Sebastian on this episode of We Got Company for an honest, behind-the-scenes look at the grind of stand-up. Despite some serious nerves, Robby holds her own as the two swap stories about the realities of the comedy world. They discuss how to build unshakeable confidence on stage, discovering your true comedic voice, and letting your upbringing shape your point of view. Robby details her unpredictable journey from the writers' room to acting and now owning the stand-up stage. We also learn why both comedians feel incredibly grateful that making people laugh allows them to travel the globe and experience the world.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Diane Kruger: The Power of Names (Re-Release) Oct 12, 2026

Show notes

We're looking back at Rob's excellent 2022 conversation with the brilliant actress Diane Kruger. On this episode, hear what inspired Diane to write her children's book "A Name From the Sky", what it was like working on Inglourious Basterds, and what it took to break out of the box Hollywood tried to put her in after playing Helen of Troy. This episode originally aired in 2022. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Sophia Bush: A Derpy Blazer will Fix it! (Re-Release) Oct 08, 2026

Show notes

We're looking back at Rob's interview with actress Sophia Bush! From One Tree Hill to Chicago P.D. to Grey's Anatomy, she's been a fixture on our TVs for years. Rob and Sophia discussed why Sophia ended up not staring in a Terminator film, how her time doing debate has helped her podcast career, and how Rob helped launch Dick Wolf's career. This episode originally aired in 2022. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Julie Bowen: What Am I Holding Back? (Re-Release) Oct 01, 2026

Show notes

This week, we're looking back at Rob's conversation with "Modern Family" and "Happy Gilmore" star Julie Bowen. Find out how Julie has crafted her art of not caring, why she's done with dating, and info on her pivot from acting to directing. This episode originally aired in 2022.

Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Busy Philipps: The Right Time (Re-Release) Sep 28, 2026

Show notes

You know her and love her from Dawson's Creek, Freaks and Geeks, Girls5eva, and much more... it's Busy Philipps! We're looking back at Rob's 2022 conversation with the actress, where they discuss the inside scoop on her experience at the Academy Awards, why she feels out of place in NYC, which SNL star is her fairy godmother, and why she lost so many roles to Tara Reid. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Jenny Slate: Throw Me a Bone (Re-Release) Sep 24, 2026

Show notes

Rob spoke to his Parks & Rec co-star Jenny Slate back in 2021 for one of our favorite Literally! episodes ever. Hear Jenny and Rob discuss ASMR, meeting on the set of Parks & Recreation, Jenny’s SNL audition, and their allergy to cynicism. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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