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    Technology

    Latent Space: The AI Engineer Podcast

    The podcast by and for AI Engineers! In 2025, over 10 million readers and listeners came to Latent Space to hear about news, papers and interviews in Software 3.0.

    We cover Foundation Models changing every domain in Code Generation, Multimodality, AI Agents, GPU Infra and more, directly from the founders, builders, and thinkers involved in pushing the cutting edge. Striving to give you both the definitive take on the Current Thing down to the first introduction to the tech you’ll be using in the next 3 months! We break news and exclusive interviews from OpenAI, Anthropic, Gemini, Meta (Soumith Chintala), Sierra (Bret Taylor), tiny (George Hotz), Databricks/MosaicML (Jon Frankle), Modular (Chris Lattner), Answer.ai (Jeremy Howard), et al.

    Full show notes always on https://latent.space

    Sponsorship and business inquiries: business@latent.space

    www.latent.space

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    Copyright: © Latent.Space

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    Latest Episodes:
    Physical AI that Moves the World — Qasar Younis & Peter Ludwig, Applied Intuition Apr 27, 2026
    Show notes

    From building Applied Intuition from YC-era autonomy tooling into a $15B physical AI company, Qasar Younis and Peter Ludwig have spent the last decade living through the full arc of autonomy: from simulation and data infrastructure for robotaxi companies, to operating systems for safety-critical machines, to deploying AI onto cars, trucks, mining equipment, construction vehicles, agriculture, defense systems, and driverless L4 trucks running in Japan today. They join us to explain why “physical AI” is not just LLMs on wheels, why the real bottleneck is no longer model intelligence but deployment onto constrained hardware, and why the future of autonomy may look less like one-off demos and more like Android for every moving machine.We discuss:* Applied Intuition’s mission: building physical AI for a safer, more prosperous world, powering cars, trucks, construction and mining equipment, agriculture, defense, and other moving machines* Why physical AI is different from screen-based AI: learned systems can make mistakes in chat or coding, but safety-critical machines like driverless trucks, autonomous vehicles, and robots need much higher reliability* The evolution from autonomy tooling to a broad physical AI platform: starting with simulation and data infrastructure for robotaxi companies, then expanding into 30+ products across simulation, operating systems, autonomy, and AI models* Why tooling companies came back into fashion: Qasar on why developer tooling looked unfashionable in 2016, why Applied Intuition still bet on it, and how the AI boom made workflows and tools central again* The three core buckets of Applied Intuition’s technology: simulation and RL infrastructure, true operating systems for vehicles and machines, and fundamental AI models for autonomy and world understanding* Why vehicles need a real AI operating system: real-time control, sensor streaming, latency, memory management, fail-safes, reliable updates, and why “bricking a car” is much worse than bricking an iPad* Physical machines as “phones before Android and iOS”: Peter explains why today’s vehicle and machine software stack is fragmented across many operating systems, and why Applied Intuition wants to consolidate the platform layer* Coding agents inside Applied Intuition: Cursor, Claude Code, internal adoption leaderboards, and how AI tools are changing engineering workflows even in embedded systems and safety-critical software* Verification and validation for physical AI: why evals get harder as models improve, how end-to-end autonomy changes simulation requirements, and why neural simulation has to be fast and cheap enough to make RL practical* From deterministic tests to statistical safety: why autonomy validation is shifting from binary pass/fail requirements toward “how many nines” of reliability and mean time between failures* Cruise, Waymo, and public trust: Qasar and Peter discuss why autonomy failures are not just technical issues, how companies interact with regulators, and why Waymo is setting a high bar for the industry* Simulation vs. reality: why no simulator perfectly represents the real world, how sim-to-real validation works, and why real-world testing will never disappear* World models for physical AI: hydroplaning, construction equipment, visual cues, cause-and-effect learning, and where world models help versus where they are not enough* Onboard vs. offboard AI: why data-center models can be huge and slow, but onboard vehicle models need millisecond-level latency, low power, small size, and distillation-like efficiency* Why physical AI is not constrained by model intelligence alone: the hard part is deploying models onto real hardware, under safety, latency, power, cost, and reliability constraints* Legacy autonomy vs. intelligent autonomy: RTK GPS in mining and agriculture, why hand-coded path-following worked for decades, and why modern systems need perception and dynamic intelligence* Planning for physical systems: how “plan mode” applies to robotaxis, mining, defense, and multi-step physical tasks where actions change the state of the world* Why robotics demos are not production: the brittle last 1%, humanoid reliability, DARPA Grand Challenge-style prize policy, and the advanced engineering gap between research and deployment* Applied Intuition’s hard-earned lessons: after nearly a decade, Peter says they can look at a robotics demo and predict the next 20 problems the company will hit* Qasar’s advice to founders: constrain the commercial problem, avoid copying mature-company strategies too early, and remember that compounding technology only matters if you survive long enough to see it compound* Why 2014 YC advice may not apply in 2026: capital markets, AI company dynamics, and the difference between building in stealth with a deep network versus building as a new founder today* What Applied is hiring for: operating systems, autonomy, dev tooling, model performance, evals, safety-critical systems, hardware/software boundaries, and engineers with deep curiosity about how things workApplied Intuition:* YouTube: https://www.youtube.com/@AppliedIntuitionInc* X: https://x.com/AppliedInt* LinkedIn: https://www.linkedin.com/company/applied-intuition-incQasar Younis:* X: https://x.com/qasar* LinkedIn: https://www.linkedin.com/in/qasar/Peter Ludwig:* LinkedIn: https://www.linkedin.com/in/peterwludwig/Timestamps00:00:00 Introduction: Applied Intuition, Physical AI, and 10 Years of Building00:01:37 Physical AI vs. Screen AI: Why Safety-Critical Changes Everything00:02:51 The Origin Story: Tooling, YC, and the Scale AI Comparison00:05:41 The Three Buckets: Simulation, Operating Systems, and Autonomy Models00:11:10 Hardware, Sensors, and the LiDAR Question00:14:26 The Operating System Layer: Why Vehicles Are Like Pre-Android Phones00:19:13 Customers, Licensing, and the Better-Together Stack00:21:19 AI Coding Adoption: Cursor, Claude Code, and the Bimodal Engineer00:26:41 Verifiable Rewards, Evals, and Neural Simulation00:31:04 Statistical Validation, Regulators, and the Cruise Lesson00:40:25 World Models, Hydroplaning, and Cause-Effect Learning00:43:34 Onboard vs. Offboard: Latency, Embedded ML, and Distillation00:50:57 Plan Mode for Physical Systems and Next-Token Prediction Universally00:53:04 Productionization: The 20 Problems Every Robotics Demo Will Hit00:58:00 Founder Advice: Constraints, Compounding Tech, and Mature-Company Mimicry01:05:41 Hiring Philosophy: Hardware/Software Boundary and Engineering Mindset01:08:50 General Motors Institute, Education, and the Curiosity MindsetTranscriptIntroduction: Applied Intuition, Physical AI, and 10 Years of BuildingAlessio [00:00:00]: Hey everyone, welcome to the Latent Space Podcast. This is Alessio, founder of Kernel Labs, and I’m joined by Swyx, editor of Latent Space.Swyx [00:00:10]: And today we’re very honored to have the founders of Applied Intuition, Qasar and Peter. Welcome.Qasar [00:00:17]: You guys really know how to turn it on to podcast mode. That was, you guys are real pros at this.Qasar [00:00:23]: They were just joking around right before this, and then they flipped it pretty quick.Alessio [00:00:29]: Oh, yeah, it’s good to have you guys. Maybe you just wanna introduce yourself so people know the voice on the mic and they’ll know what they’re hearing.Peter [00:00:33]: Oh, sure. Yeah, I’m Peter Ludwig. I’m the co-founder and CTO of Applied Intuition.Qasar [00:00:38]: And my name is Qasar Younis. I am the CEO and co-founder with Peter.Alessio [00:00:42]: Nice. Can you guys give the high-level overview of what Applied Intuition is? And I was reading through some of the Congress files, when you went out there, Peter, and eighteen of the top twenty global non-Chinese automakers, you two guys, you have customers in agriculture, defense, construction. I think most people have heard of Applied Intuition tied to YC when it was first started, and then you were kinda in stealth for a long time, so maybe just give people the high-level overview of what it is today, and then we’ll dive into the different pieces.Peter [00:01:10]: Yeah. So at Applied Intuition, our mission is to build physical AI for a safer, more prosperous world. And so we work on physical AI for all different types of moving systems, everything from cars to trucks to construction and mining equipment, to defense technologies. And we’re a true technology company, so we build and sell the technology, and we sell it to the companies that make the machines. We sell it to the government, really anyone that wants to buy a technology to make machines smart.Physical AI vs. Screen AI: Why Safety-Critical Changes EverythingQasar [00:01:38]: Yeah. And I think in the broader AI landscape, a lot of the focus, rightfully so in the last, three years has been on large language models, and so everything fits in a screen. Like, whether it’s code complete products or things like that. And what’s different about us is we’re deploying intelligence onto a lot of things that don’t have screens. they’re physical machines. There are sometimes screens within the cabin or for example of a car or a truck or something like that, but most of the value we provide is putting intelligence that is in safety critical environments. So that those two words are really important because learn systems can make mistakes if you’re asking for, like, some, so something like, “Tell me about these podcast hostsQasar [00:02:28]: that I’m about to go meet.” But you can’t do that obviously when you run, like, as an example, we run driverless trucks in Japan right now, as we speak. We can’t have errors. Those are L4 trucks. Yeah.Alessio [00:02:40]: Yeah. Was that always the mission? I remember initially, I think people put you and Scale AI very similarly for some things about being kinda like on the data infrastructure side of things. What was the evolution of the company?The Origin Story: Tooling, YC, and the Scale AI ComparisonPeter [00:02:51]: Well, from the very beginning, we always wanted to, really be a technology company that helped generally push forward the industrial sector. And so we started off working in autonomy. Our very first customers were robotaxi companies. And we started off doing a lot of work in simulation and data infrastructure. And then over the years, we’ve expanded our portfolios. Now we have, over thirty products, and it’s a pretty broad technology play within the landscape of physical AI.Qasar [00:03:19]: Yeah, I think the Scale reason is because we’re all YC Universe companies. But it was a very different company. Scale, was, is more of a services company, data labeling company fundamentally. We started and still are, do a lot of tooling. So like, you think developer tooling is now in vogue again, thanks to the AI boom. But honestly, ten years ago, it was out of vogue. It w Like, doing a tooling company in 2016, 2017 was not, like, the thing to do because, I don’t know if you remember, the VCs generally, their views was that toolings are They’re just workflows, and workflows ultimately are not really interesting. And we’ve gone and come, full circle with that. But when we started the company, our kind of it’s kinda like in the periphery of what the company wants to be. It was like, from our earliest days, like, we wanna deploy software on physical machines, like on cars and on trucks and things like that. And obviously, we didn’t know that the transformer boom was gonna happen. We didn’t know that autonomy systems would become end-to-end. Those things we didn’t know. And why that’s important when autonomy systems become end-to-end, it is just now those models can be generalized to, multiple form factors. And so back nine, ten years ago, tooling was a great way, and still is a great way to, build the technology and sell technology to our end customers, a lot of them who wanna build this stuff themselves. And so we just offer like a spectrum of solutions from you can just use like one part of a development suite of tools all the way to buying the full thing. The way to think about the company, or at least the way we think about the company is, as Peter said, a technology provider. It’s kinda like, what NVIDIA does or what an AMD, but we just don’t do chips.Qasar [00:05:06]: We don’t do silicon. But we’re a technology provider fundamentally. And I think even, we used to joke when we started the company, like, we’re not the guys to build, like, Instagram. Like that was just towards That’s not our That’s just not us in a most fundamental way. IAlessio [00:05:20]: You have thoughts.Qasar [00:05:21]: Yes.Qasar [00:05:22]: Well, it’s, it’s I mean, I think it’s just like what And I mean, we worked on Maps and stuff, Google Maps. Consumer products are extremely difficult for a lot of different reasons. It just, I think doesn’t scratch the itch. I think we’re like Michigan guys who are kind of more of that traditional engineering kind of a realm, or lineage. we used to jokeThe Three Buckets: Simulation, Operating Systems, and Autonomy ModelsPeter [00:05:41]: I gotta say, though, what was clear ten years ago was that there was so much more that was possible with software and AI in vehiclesPeter [00:05:47]: and that was generally the space that we started in ten years ago.Peter [00:05:51]: And the precise path that we’ve taken over the years, I think we’ve been strategic, and we’ve adjusted to make sure that we’re actually building stuff that’s valuable to the market. And like, the technology has changed so much. Like our own technology stack has completely changed, I would say, roughly every two years. And so now we’ve probably done, let’s say, four complete evolutions of our own technology stack. And I sort of see that cadence roughly keeping up.Peter [00:06:13]: And so the way even we think about engineering is almost on this two-year horizon, we’re preparing ourselves that, hey, like, we wanna invest the appropriate amount, but then also be very dynamic as the research gets published and as our research team figures out new advancements and adapting to that.Qasar [00:06:27]: Yeah. One thing that has been consistent is the type of people we’ve, we’ve recruited. It’s engineers who are fall into the sometimes very traditional, like, GoogleQasar [00:06:38]: -gen suite, but way different from, other companies. We are hiring folks who really know the intersection of hardware and software, who know really low-level systems. Obviously, traditional ML researchers and folks who’ve, actually, put ML systems into production. That’s been pretty consistent. I think that, like, you look at the mix of our engineering, eighty-three percent of the company is engineering, so it’s, like, a giant list.Qasar [00:07:05]: A lot of engineers.Alessio [00:07:06]: Which, by the way, a thousand engineersQasar [00:07:07]: Yeah. A thousand engineers.Alessio [00:07:08]: that’s on your website, so I imagine it’s up to date.Qasar [00:07:11]: It is, it is up to date, yes. Yes.Alessio [00:07:12]: okay. And then forty-plus founders.Qasar [00:07:15]: Yeah. We would tend to also, This was more luck than strategy. But we’ve recruited a lot of ex-founders. It’s been a great place for founders, YC and non, ‘cause obviously I know a lot of the YC folks. It’s kind of like we recruit a lot of Google people.Qasar [00:07:33]: For them to exercise both their technical and non-technical skills because, we’re, we’re, we’re on the applied side. We have a research team that we do fundamental research, we publish, and we’ve, we’ve had great traction there. But fundamentally, the business wants to take this intelligence and deploy it into production and there’s, like, a certain type of person that’s more interested in that.Alessio [00:07:54]: Yeah. You mentioned the tech stack, Peter, so I just wanted to give you some rein to just go into it. I’m interested in where Wayve Nutrition, starts and ends in some sense, what won’t you do? What, do you do that’s common among…

    Full show notes at the publisher

    AIE Europe Debrief + Agent Labs Thesis: Unsupervised Learning x Latent Space Crossover Special (2026) Apr 23, 2026
    Show notes

    Today, we check in a year after the first Unsupervised Learning x Latent Space Crossover specialto discuss everything that has changed (there is a lot) in the world of AI. This episode was recorded just after AIE Europe, but before the Cursor-xAI deal.Unsupervised Learning is a podcast that interviews the sharpest minds in AI about what’s real today, what will be real in the future and what it means for businesses and the world - helping builders, researchers and founders deconstruct and understand the biggest breakthroughs.Thanks to Jacob and the UL production team for hosting and editing this!Jacob Effron* LinkedIn: https://www.linkedin.com/in/jacobeffron/* X: https://x.com/jacobeffronFull Episode on Their YouTubeWe discuss:* swyx’s view from the center of the AI engineering zeitgeist: OpenClaw, harness engineering, context engineering, evals, observability, GPUs, multimodality, and why conference tracks now reveal what matters most in AI* Whether AI infrastructure has finally stabilized: why “skills” may be the minimal viable packaging format for agents, why infra companies have had to reinvent themselves every year, and why application companies have had an easier time surviving model volatility* The vertical vs. horizontal AI startup debate: why application companies can act as the outsourced AI team for enterprises, why some horizontal companies still matter, and why sandboxes may be the clearest reinvention of classic cloud infrastructure for the AI era* The “agent lab” playbook: starting with frontier models, specializing for your domain, then training your own models once you have enough data, workload, and user behavior to justify the cost and latency savings* Why domain-specific model training is real, not just marketing: how companies like Cursor and Cognition can get users to choose their in-house models, and why search, domain specialization, and distillation are becoming more important* Open models, custom chips, and alternative inference infrastructure: why swyx has turned more bullish on open source, why non-NVIDIA hardware is suddenly getting real attention, and why every 10x speedup can unlock new product experiences* What it means to sell to agents instead of humans: why agent experience may mostly just be good developer experience by another name, why APIs and docs matter more than ever, and how pretraining-data incumbents are compounding advantages in an agent-first world* Why memory and personalization may become the next big wedge: today’s models mostly reward frequency of mentions, but in the future, swyx expects product choice to be shaped much more by personalized memory systems* The state of the AI coding wars: why coding has become one of the largest and fastest-growing categories in AI, how Anthropic, OpenAI, Cursor, and Cognition have all ridden the wave, and why the category may still have more room to run* Capability exploration vs. efficiency: why the industry is still in a token-maxing, experiment-heavy phase where people are rewarded for spending more rather than less* Claude Code vs. Codex and the strange stickiness of coding products: why first magical product experiences may matter more than expected, and why the bigger mystery may be why only a few names have emerged as real winners so far* What the end state of the coding market might look like: two major players, a longer tail of niche products, and possible disruption if Microsoft, Mistral, xAI, or the Chinese labs push harder into coding* Where application companies still have room against the labs: why frontier labs are trying to expand into verticals like finance and healthcare, but still leave space for focused companies that own the workflow and the last mile* Why coding may be a preview of every other AI market: the first category to truly go parabolic, the clearest example of foundation model companies colliding with application companies, and a template for how future vertical AI markets may develop* Why AI valuations now feel unbounded: from billion-dollar ARR products built in a year to trillion-dollar market caps, swyx and Jacob unpack how the AI market has broken traditional startup intuitions about scale and durability* Consumer AI vs. coding AI: why ChatGPT’s consumer category may have plateaued on frequency and product design, while coding continues to feel like a daily-use category with real momentum* The next product frontier beyond coding: consumer agents, computer use, and “coding agents breaking containment,” with swyx’s thesis that 2025 was the year of coding agents and 2026 may be the year they begin to do everything else* Whether foundation models are really killing startup categories: why swyx is less worried for early founders, more worried for mid-size startups and traditional SaaS, and why building something ambitious may now be the best job interview for a frontier lab* AI vs. SaaS and the internal culture war around adoption: the tension between AI-native employees who want to rip out expensive software and skeptics who think quick AI-built replacements create fragile systems* Why traditional SaaS may be under real pressure: swyx’s own experience spending six figures on event and sponsor management software, the temptation to rebuild it cheaply with AI, and the broader question of whether teams will trust custom AI-native replacements* Biosafety, security, and frontier model access: why swyx raised biosafety at a dinner with Anthropic’s Mike Krieger, why Krieger argued security is the bigger issue, and what restricted model releases reveal about Anthropic vs. OpenAI* The era of giant models: why 10T+ parameter systems may only be a temporary rationing phase before bigger clusters arrive, why labs may increasingly keep their most powerful models private for distillation, and why scale alone no longer feels like a complete answer* Memory as the slowest scaling factor in AI: why context windows have improved far more slowly than people hoped, why million-token context still has not changed most real workflows, and why memory may be the key bottleneck for the next generation of systems* What swyx changed his mind on in the past year: becoming more bullish on open models, more convinced that the top tier of agent startups behaves very differently from the median AI company, and more optimistic about fine-tuning and specialized model adaptation* “Dark factories” and zero-human-review coding: the next frontier after zero human-written code, where models not only write the code but ship it without human review, forcing companies to rethink testing and verification from first principles* Why RL and post-training may matter more than people assumed: even if the resulting models get thrown out every few months, the data, workflows, and domain-specific improvements persist* Synthetic rubrics, Doctor GRPO, and multi-turn RL: why reinforcement learning is becoming much more domain-specific and multi-step than many people realize, opening the door to much deeper customization* The next frontier after coding: memory, personalization, and world models, including why swyx thinks world models matter not just for robotics or gaming, but for giving AI something closer to lived understanding* Fei-Fei Li, spatial intelligence, and the Good Will Hunting analogy: the idea that today’s LLMs may know everything by reading it all, but still lack the lived experience that turns knowledge into a deeper kind of intelligenceTimestamps* 00:00:00 Intro preview: AI coding wars, startup pressure, and market structure* 00:00:28 Welcome to the Latent Space × Unsupervised Learning crossover* 00:01:17 What AI builders are focused on now: OpenClaw, harnesses, and infra* 00:04:33 Why AI infra is harder than apps, and where startups can still win* 00:06:39 Should companies train their own models?* 00:09:28 Open models, custom chips, and the new inference race* 00:11:25 Designing products for agents, not just humans* 00:16:49 The state of the AI coding wars in 2026* 00:19:27 Capability exploration, token-maxing, and why coding is going parabolic* 00:21:41 What the end state of the coding market could look like* 00:23:50 Where app companies still have room against the labs* 00:27:02 Why AI valuations and market swings feel unprecedented* 00:28:56 Consumer AI vs. coding AI, and why sticky products still matter* 00:32:28 What the next breakthrough product experience might be* 00:32:53 2026 thesis: coding agents break containment and eat the world* 00:35:27 Are foundation models wiping out startup categories?* 00:37:33 AI vs. SaaS, vibe coding, and internal team tensions* 00:40:01 Biosafety, security, and the politics of restricted model releases* 00:42:19 Giant models, compute constraints, and the limits of scale* 00:44:30 Memory as the real bottleneck in AI* 00:44:57 Why swyx changed his mind on open models* 00:47:44 Dark factories and the future of zero-human-review coding* 00:49:36 Why post-training and RL may matter more than people think* 00:51:50 Memory, world models, and the next frontier of intelligence* 00:53:54 The Good Will Hunting analogy for LLMs* 00:54:21 OutroTranscript[00:00:00] swyx: Isn’t that crazy? That number is just mind boggling.[00:00:03] Jacob Effron: What is the state of the AI coding wars today?[00:00:05] swyx: We’re in a phase of sort of like capability exploration. The general thesis that I have been pursuing now is that the same way that 2025 was a year coding agents 2026 is coding agents breaking containments to do everything else.[00:00:16] Jacob Effron: Do you worry about the foundation models just getting into a bunch of these startup categories?[00:00:21] swyx: Mid-size startups. Yes.[00:00:23] Jacob Effron: What do you think the end state of this market is[00:00:25] swyx: for the market structure to, to significantly change? There would be[00:00:28] Jacob Effron: today on unsupervised learning. We had a, a fun episode and what’s really become an annual tradition, a crossover episode with our friends at Latent space.Swix and I sat down and we talked about everything happening in the AI ecosystem today. What we thought of the various changes at the model layer, what’s happening in the infra world, the coding wars, and a bunch of other things. It’s a ton of fun to do this with someone I really respect and another great podcaster in the game.Without further ado, here’s our episode. Well switch. This is, uh, super fun to be back with another unsupervised learning, uh, latent space crossover episode.[00:01:02] swyx: Yeah,[00:01:02] Jacob Effron: I feel like a lot of places we could start, but you know, one thing I always find fascinating, uh, about the way you spend your time is you obviously are like at the epicenter of this engineering movement and community, and you run these events and conferences and put on these.Awesome talks and, and I think just have a great pulse on the zeitgeist of what’s going on.[00:01:16] swyx: Yeah.[00:01:17] Jacob Effron: Maybe to, to start just what are the biggest topics people are thinking about right now?[00:01:21] swyx: Yeah, so I just came back from London, uh, where we did a IE Europe and we’re doing roughly one per quarter now, which Yeah, you’ve[00:01:27] Jacob Effron: really up[00:01:27] swyx: the, hopefully[00:01:28] Jacob Effron: up the, up the pace.[00:01:29] swyx: It’s trying. We’re trying to match AI speed, youknow?[00:01:30] Jacob Effron: Yeah, exactly. The tops would be completely different, I imagine. Uh,[00:01:33] swyx: yeah. You know, I definitely curate the tracks, like you can see what I think. When you see the track list and the, the speakers that I invite, obviously Open Claw is like the story of the last four or five months, and then be, be just below that.I would consider harness engineering, context engineering to be two related topics in agents and rag. And then there’s a long tail of Evergreen stuff like evals, observability, GPUs, uh, and uh, LM infra and just general, just in general. We also have other updates on like multimodality and, uh, generative media, let’s call it.Um, but I definitely, the, the first three that I mentioned are top of mind people. Yeah.[00:02:13] Jacob Effron: I think harness is particular like, so interesting. Um, you know, there was this tweet from Harrison Chase, the, the lane chain, CEO, that, that caught my eye recently where he said, you know, it finally feels like we have stability, uh, around the infrastructure for, uh, you know, around ai.And I think what. He basically was implying his like, look over the past two, three years as a company at the epicenter of AI infrastructure, it was a bit like playing whack-a-mole, right? You were constantly moving around with, however, the building patterns were evolving[00:02:36] swyx: for Harrison for sure. Right? Like he’s basically had to reinvent the company every year since he started Lang Chain.Right? It was Lang chain, Ang graph and LP agents and like, uh, I think he’s like one of the most nimble, adept sharp people about this. Yeah. Yeah.[00:02:49] Jacob Effron: Saying now, now is finally the time stability[00:02:51] swyx: this. Yeah.[00:02:52] Jacob Effron: Yeah. Um, do you buy that or what have you kind of make of that take?[00:02:56] swyx: I think that. It, it’s very expensive to say this Time is different sometimes, but when you’re just writing code, like it’s actually okay to just like try to make a call and I think it may not even matter if this call is right or not.Like I just don’t even care that much because you can be right on a thesis, but if you don’t, you don’t figure out how to monetize the thesis, then who cares if you said something first that said, um, it does feel like, for example. Uh, we went through a lot of different ways of passion packaging integrations up with, uh, with agents.And it feels like we’ve landed at skills, which is like the minimal viable format. Yeah. Which is just a markdown file, uh, with some scripts attached to it, and I don’t see how it can be more simple than that. And so there is some justification for. The stability around harnesses. I feel like there may be more adaptation with regards to maybe like the real time elements or subagents or memory or any of those like agent disciplines, let’s call it in, in agent engineering.Uh, but if, if the thesis is that, okay, you just want agents are LMS with tools in the loop with a file system, what they can do. Retrieval with, with skills and all these like standard tooling that now seems to be relatively consensus then probably. That makes sense. Um, I just think like there’s no point trying to stake your reputation on this thesis that we’re there because if it changes again, just change with it.It’s fine.[00:04:33] Jacob Effron: Yeah. It’s always, you know, I’ve always been struck by how that is. Much more challenging for infrastructure companies and application companies. Like obviously I think, yeah. You know, on the application side you’ve seen, you know, Brett Taylor from Sierra Max, from Lara. Like, they’re like, look, we build, you know, what’s ahead of the models and we’re willing to throw everything out every three months, you know, as the models get better and better.Exactly. Yeah. But the thing you at least have there is you have. Uh, you have an end customer, right? That’s like decently sticky. Um, you know, they will mostly stick, you know, they’ll, they’ll give you a shot at least of, of building these things. What I’ve always found more challenging, uh, at, at the kind of like, you know, reinvent yourself every three months of the infrastructure layer, it’s like, you know, developers are definitely a, a pickier audience maybe than an accounting firm or, uh, you know, a bank.Yeah. And so it’s definitely a, a, a more challenging position to be in to, to have to constantly reinvent yourself.[00:05:17] swyx: Yeah. Yeah. Yeah. And, and like when they turn, it’s like. Very complete. Like, they’ll leave to like the, the hot new thing, uh, because there’…

    Full show notes at the publisher

    Shopify’s AI Phase Transition: 2026 Usage Explosion, Unlimited Opus-4.6 Token Budget, Tangle, Tangent, SimGym — with Mikhail Parakhin, Shopify CTO Apr 22, 2026
    Show notes

    Early bird discounts for the San Francisco World’s Fair, the biggest AIE gathering of the year, end today - prices will go up by ~$500 tonight so do please lock in ASAP!From near-universal AI tool adoption inside Shopify to internal systems for ML experimentation, auto-research, customer simulation, and ultra-low-latency search, Mikhail Parakhin joins us for a deep dive into what it actually looks like when a 20-year-old, $200B software company goes all-in on AI. We cover why Shopify has become much more vocal about its internal stack, what changed after the December model-quality inflection, and why the real bottleneck in AI coding is no longer generation, but review, CI/CD, and deployment stability.We also go inside Tangle, Tangent, SimGym, which are three major AI initiatives that Shopify is doing to make experimentation reproducible, optimization automatic, customer behavior simulatable, and search and catalog intelligence faster and cheaper at scale. Along the way, Mikhail explains UCP, Liquid AI, and why token budgets are directionally right but often measured badly, why AI-written code can still increase bugs in production, what makes Shopify’s customer simulation defensible, and what he learned from the Sydney era at Bing.We discuss:* Mikhail’s path from running a major Microsoft business unit spanning Windows, Edge, Bing, and ads to becoming CTO of Shopify* Why Shopify is talking more publicly about AI now, and why staying at the frontier has become necessary for the company* Shopify’s internal AI adoption curve, the December inflection, and why CLI-style tools are rising faster than traditional IDE-based tools* Why Jensen Huang is directionally right on token budgets, but raw token count is still the wrong way to evaluate engineering output* Why the real unlock is not more agents in parallel, but better critique loops, stronger models, and spending more on review than generation* Why AI coding can still lead to more bugs in production even if models write cleaner code on average than humans* Why Shopify built its own PR review flow, and why Mikhail thinks most off-the-shelf review tools miss the point* How PR volume, test failures, and deployment rollback are becoming the real bottlenecks in the agent era* Why Git, pull requests, and CI/CD may need a new metaphor once code is written at machine speed* What Tangle is, and how Shopify uses it to make ML and data workflows reproducible, collaborative, and production-ready from the start* Why Tangle is different from Airflow, and why content-addressed caching creates network effects across teams* What Tangent is, and how Shopify is using auto-research loops to optimize search, themes, prompt compression, storage, and more* Why Tangent is becoming a democratizing tool for PMs and domain experts, not just ML engineers* Why AutoML finally feels real in the LLM era, and where auto-research still falls short today* Why Tangle, Tangent, and SimGym become much more powerful when combined into one system* What SimGym is, why simulated customers only work if you have real historical behavior, and why Shopify’s data gives it a moat* How SimGym evolved from comparing A/B variants to telling merchants what to change on a single live storefront to raise conversions* Why customer simulation is so expensive, from multimodal models to browser farms to serving and distillation costs* How Shopify models merchant and buyer trajectories, runs counterfactuals, and thinks about interventions like discounts, campaigns, and notifications* Why category-level behavior is so different across commerce, and why ideas like Chinese Restaurant Processes are showing up again in practice* Shopify’s new UCP and catalog work, including runtime product search, bulk lookups, and identity linking* Why Shopify is using Liquid AI, and why Mikhail sees it as the first genuinely competitive non-transformer architecture he has used in practice* Where Liquid already works inside Shopify today, from low-latency query understanding to large-scale catalog and Sidekick Pulse workloads* Whether Liquid could become frontier-scale with enough compute, and why Shopify remains pragmatic and merit-based about model choice* Who Shopify is hiring right now across ML, data science, and distributed databases* The Sydney story at Bing, why its personality was not an accident, and what Mikhail learned from deliberately shaping AI character early onMikhail Parakhin* LinkedIn: https://www.linkedin.com/in/mikhail-parakhin/* X: https://x.com/MParakhinTimestamps00:00:00 Introduction: Mikhail Parakhin, Microsoft, and Shopify00:01:16 Why Shopify Is Talking More About AI00:02:29 Internal AI Adoption at Shopify and the December Inflection00:06:54 Token Budgets, Jensen Huang, and Why Usage Metrics Can Mislead00:10:55 Why Shopify Built Its Own AI PR Review System00:12:38 AI Coding, More Bugs, and the Real Deployment Bottleneck00:14:11 Why Git, PRs, and CI/CD May Need to Change for Agents00:18:24 Tangle: Shopify’s Reproducible ML and Data Workflow Engine00:21:19 Why Tangle Is Different from Airflow00:26:14 Tangent: Auto Research for Optimization and Experimentation00:30:07 How Tangent Democratizes Experimentation Beyond ML Engineers00:33:06 The Limits of Auto Research00:36:36 Why Tangle, Tangent, and SimGym Compound Together00:37:20 SimGym: Simulating Customers with Shopify’s Historical Data00:42:47 The Infra Behind SimGym00:46:00 Why SimGym Gets Better with Real Customer History00:47:30 Counterfactuals, HSTU, and Modeling Merchant Trajectories00:51:55 CRPs, Clustering, and Category-Level Customer Behavior00:53:30 UCP, Shopify Catalog, and Identity Linking00:55:07 Liquid AI: Why Shopify Uses Non-Transformer Models00:59:13 Real Shopify Use Cases for Liquid01:03:00 Can Liquid Scale into a Frontier Model?01:09:49 Hiring at Shopify: ML, Data Science, and Databases01:10:43 Sydney at Bing: Personality Shaping and AI Character01:13:32 Closing ThoughtsTranscript[00:00:00] swyx: Okay. We’re here in the studio, a remote studio, with Mikhail Parakhin, CTO of Shopify. Welcome.[00:00:08] Mikhail Parakhin: Thank you. Welcome.[00:00:10] swyx: I don’t even know if I should introduce you as CTO of Shopify. I feel like you have many identities. Uh, you led sort of the, the Bing ML team, I guess, uh, uh, or ads team. I, I don’t know, I don’t know, uh, you know, it’s, uh, people va-variously refer you as like CEO or, or, uh, I don’t know what that, that, that said previous role at Microsoft was.[00:00:29] Mikhail Parakhin: Uh, that was... Yeah, my previous role w- at Microsoft was the-- I actually was the CEO of one of Microsoft’s business units, which included, as I, you know, as we discussed, all the things that people like to laugh about, uh, including Windows and Edge and Bing and ads and everything.[00:00:47] swyx: Yeah, yeah. What a, what a, what a wild time.You’ve obviously, uh, done a lot since you landed at Shopify. Uh, one of the reasons I reached out was because you started promoting more sort of internal tooling, uh, primarily Tangle, but also a lot of people have seen and adopted Tobi’s QMD, uh, and obviously, I think, uh, Shopify has always been sort of leading in terms of, uh, engineering.I think more-- it’s just more recent that you guys have been more vocal about your sort of AI adoption. Is that, is that true?[00:01:16] Mikhail Parakhin: Well, I think AI tools in general are fairly recent development, uh, and we’ve-- Shopify, you know, at this stage of its development, we’re developing AI in-in-house and other, uh, building tools that use AI and, you know, interfacing with the wider AI community, uh, you know, are on the sort of the, uh, runaway trajectory.So it just did by sort of natural byproduct. We, we talk about it more also. We just, uh, just even yesterday, Andrej Karpathy was famous in tweeting about, oh, are there some, uh, ways, uh, that, that you can organize your agents to store the data and then, uh, look up the data so that you don’t have to research or, or lose context every- Yestime. And a little bit tongue in cheek, I tweeted that, “Hey, we’ve, we’ve done it much earlier, and we even have different approaches, Tobi and I.” Tobi, of course, is a big fan of QMD, and I’m more of a SQL, SQLite fan. But, uh, yeah, very similar things that we’ve already done here. The point is, yeah, we’re very dynamic, you know, explosively growing company, and we have to be at the forefront of AI adoption, obviously.[00:02:29] swyx: Yeah. Yeah. Um, you, your team kindly prepared some slides actually that we were gonna bring up on to, uh, the screen. I think I can, I can screen share, and then we can kind of go through some of the shocking stats that maybe, maybe put some numbers to what exactly is going on. So here we have, uh- An internal AI tool adoption chart.What are we looking at here? What ?[00:02:54] Mikhail Parakhin: Yeah, this is very interesting statistics. Uh, this is number of daily active workers, you know, think of, uh, DAO, basically the active users of-[00:03:05] swyx: Yeah ...[00:03:05] Mikhail Parakhin: AI tool as a percentage of all the people in the company, right? And then- Yeah ... different AI tools. And, uh, you could see two things here is that one is the green is total.Uh, green is just total. So you could see that it approaches really % by now. It’s hard not to do your job now without interacting deeply, at least with one tool. You could see another interesting thing is just as many people commented in December was the phase transition when suddenly models gotten good enough that, that everything took off and started growing.Uh, it, it was many people noticed that the thing is that small improvements accumulated into this big change in Sep- December roughly timeframe.[00:03:52] swyx: Yeah.[00:03:52] Mikhail Parakhin: The other thing I would claim you could see is that, uh, CLI-based tools and tools that don’t require you to look at the code becoming more popular, and you could see, yeah, various versions of, uh, Cloud Code and Codex and Pi and internal development tools taking off.Uh, exactly, yeah, uh, and blue is our River, just internal agent for coding, where tools, uh, that require IDEs such as, uh, GitHub, Copilot or Cursor, they’re not exactly shrinking, but they’re not growing as fast. Like, uh, red, red line is, is the IDE kind of tools. So you could see that they’re, they’re not experiencing as, as fast of a growth.[00:04:37] swyx: As I understand it, basically, every employee has their choice, right? Of choose whatever tool you use, and then you’re just kind of doing a, a daily sur-survey or something.[00:04:47] Mikhail Parakhin: Exactly. And, uh, we- Yeah ... the, the push is to get your job done, you can use any tool, and we effectively fund unlimited tokens for everybody.Uh, we, we do, we do try to control the models that, uh, people use, but from the bottom, not from top. Like we basically say, “Hey, please don’t use anything less than Opus four point six.”[00:05:09] swyx: Oh .[00:05:10] Mikhail Parakhin: Some people, some people end up using GPT five point four extra high. Some people use Opus four point six. Um, uh, you know, uh, there are some, uh, there are plus and minuses in going for full one million context window versus not.But, uh, we try to discourage people from using anything less than that.[00:05:28] swyx: Yeah, yeah. Got it, got it. Uh, I mean, uh, that’s, you know... The, the next chart here, it really kind of shows the expansion and the sort of December twenty twenty-five inflection, right? That, uh, people are using a lot of tokens. I think it’s also really interesting that no one was kind of abusing it in twenty twenty-five.Like it was- Had comparatively, uh, to this year, there was almost no growth. I mean, it’s still like, you know, probably, probably gave fifty percent.[00:05:56] Mikhail Parakhin: Yeah. This is just a different scale. It’s still exponential- Yeah, yeah ...growth at just a different- ...rate of expansion. Uh, there was inflection point, and Sean, I would claim the, the super interesting part here is that you could see that the distribution becoming more and more skewed.Yes. The top percentiles grow faster. So that means- Yeah ...the people in the top ten percentile, they, their consumption grows faster than seventy-five and so forth. So, uh, the distribution skews more and more towards the highest users, which is... I don’t know what it tells me. It’s like it feels not ideal, to be honest.Or maybe it’s okay. We’ll see.[00:06:36] swyx: Why does it feel not ideal? Is, is it because of, um, quantity over quality, or what’s the concern?[00:06:42] Mikhail Parakhin: Because take it to the limit. That means, you know, if, if this rate of separation continued- Ah, yes ...a year, there will be one person consuming all the tokens. So it’s just, it’s kinda strange.[00:06:54] swyx: Yeah, I mean, um, uh, I, I think internal like teaching and all that, uh, will, will help sort of distribute things more widely. But in, in the early days, of course, the people who are sort of more AI-pilled will obviously find more ways to use it than the people who are less AI-pilled. Maybe let’s, let’s call it that.I’ll just, I’ll just kinda quickly, uh, pause from the, the... You know, we will go back to the rest of the slides, but I just wanna, um, review, you know, there are a lot of CTOs of, of large companies like yourself where they’re all considering some kind of token budget, right? Like I think it’s something, something that Jensen Huang has been talking about, where like if your 200K engineer is not using 100K of tokens every year, like they’re, they’re underutilizing coding agents.Of course, Jensen Huang would say that, but like it seems a very quantity over quality approach and like some, some people are basically saying like, well, is this comparable to judging engineer quality by lines of code, right? Which we also know is like kind of flawed, but better than nothing. So I, I don’t know if you have like a sort of management take here on, on how to view this kind of, uh, metrics.[00:08:02] Mikhail Parakhin: Well, I mean, you’re, you’re baiting me. I, I like... This is my favorite topic. Uh, if you let me, I’ll probably talk for two hours on just this. I have a lot of things to say. Like I do think Jensen gotten a lot of bad press saying, “Oh, of course you’re, you know, this, uh, the- ...the cake seller says you don’t need enough cakes.”You know? Like, of course. Uh, but, uh, I actually, uh, think that’s undeserved. I think he, he’s actually right. Uh, I do think- He,[00:08:33] swyx: he’s directionally correct.[00:08:35] Mikhail Parakhin: Yeah. Yeah. He’s directionally correct for sure. Uh-[00:08:37] swyx: Who knows what the right number is? Yeah.[00:08:39] Mikhail Parakhin: The thing that I do Uh, want to say, and this is something that we learned through trial and error and very important is like two things.One is that it’s not about just consuming tokens. Uh, you can consume tokens and, and in fact, the anti-pattern is running multiple agents, too many agents in parallel that don’t communicate with each other. That’s almost useless, uh, compared to just fewer agents and burns tokens very efficiently. Uh, setting up the right critique loop, especially with the high quality models, where one agent does something, the other one, ideally with a different model, critiques it, uh, suggests ways to improve it, the agent redoes it with this critique and, and so it takes much longer.So people don’t like it because latency goes up. You know, they, they have to wait until this debate is happening. But, uh, the quality of the code is much higher. And another thing, just since you mentioned like, look, uh, uh, yeah, the overall budget is just like, uh, lines of codes. Lines of codes are exploding for everybody right now, or partially because AI is really mover balls, but partially just because AI can write a lot more code, you know, doesn’t get tired.And so you…

    Full show notes at the publisher

    🔬 Training Transformers to solve 95% failure rate of Cancer Trials — Ron Alfa & Daniel Bear, Noetik Apr 20, 2026
    Show notes

    Today, we explain this piece of “clickbait” from our guest!

    TL;DR: 95% of cancer treatments fail to pass clinical trials, but it may be a matching problem — if we better understood what patients have which tumors which will respond to which treatments, success rates improve dramatically and millions of lives can be saved — with the treatments we ALREADY have.

    See our full episode dropping today:

    Why Big Pharma is licensing AI Models

    Tolstoy famously wrote, ‘All healthy cells are alike; each cancer cell is unhappy in its own way.’ Or something like that. Cancer might be the most misunderstood disease out there. It’s not one disease, it’s a family of diseases. Hundreds, maybe thousands, of unique diseases each with its own underlying biology. With this lens, saying you’ll “cure cancer” is like saying you’ll solve legos.

    We keep hearing AI will cure cancer, but sadly it may not be so easy. Today’s guests — Ron Alfa and Daniel Bear from Noetik — thinks they can use AI to break through a core bottleneck in the treatment development process.

    GSK recently signed a $50M deal for their technology that also includes an (undisclosed) long-term licensing deals for Noetik’s models like the recently announced TARIO-2, an autoregressive transformer trained on one of the largest sets of tumor spatial transcriptomics datasets in the world. Whole-plex spatial transcriptomics is the richest way to read a tumor, and approximately ~0% of cancer patients going through standard care ever get one — and TARIO-2 can now predict an ~19,000-gene spatial map from the H&E assay every patient already has.

    Most big AI plays in BioTech have focused on discovery, and usually result in an in-house development effort (meaning tools companies usually become drug companies). This deal stands out in that it is a software licensing deal, and represents a commitment to a platform rather than a drug.

    With attention on other software tools for drug development (see the Boltz episode and Isomorphic for example), it is starting to look like the appetite of Pharma for biotech tools has finally started to grow. Why the sudden interest?

    Cancer is hard

    Biology is hard, cancer is harder. But despite this, we’ve made incredible progress. So many cancers that would have been death sentences twenty years ago are routinely survivable. It used to be our main strategy was just chemotherapy — poison you and hope the tumor dies before you do. Now, there are many treatments that actually kill a tumor and leave the rest of you intact! Immune checkpoint inhibitors like Keytruda and Opdivo target the defenses of dozens of tumor types. CAR-T therapy adds modified T-cells to your blood that can target B-cell malignancies very accurately. Antibody Drug Conjugates such as Trastuzumab combine a drug with an antibody, allowing it to target very specific (cancer) cells. We truly live in marvelous times.

    With that said, we still have a long way to go. For every type of cancer with a miracle treatment, we have many more that are still death sentences. The world spends $20-30 billion a year trying to cure cancers, with hundreds of clinical trials yearly.Yet, progress is slow with a 95% failure rate in clinical trials.

    The lab doesn’t translate to the clinic

    Are we leaving something on the table? Enter Noetik and Ron Alfa. Ron’s core thesis is that many of these “failed” treatments actually work! But we’re not looking at the right patients with the right tumors. If only we had a way to really understand the unique types of cancer biologies and which patients will respond to which treatments, we might be able to show a much higher success rate. Millions of lives (and billions of dollars) may ride on this.

    The Hard part: Blind Faith in Data Collection

    Ron and Noetik had the conviction to spend almost two years just collecting data. Lots, and lots, and lots, of data. Noetik has acquired thousands of actual human tumors, and collects a large multimodal dataset of hundreds of millions of images that allows them to create a detailed map of the cell makeup in the local environment. These are real human tumors, not frankenstein mouse models or immortal cell lines.

    This data is then fed into a massive self-supervised model, creating a “virtual cell”. This model has a deep understanding of cancer biology — Noetik has worked carefully to show it can distinguish different types of tumors. Maybe even tumors we didn’t identify as distinct previously! More recently they figured out how to scale up their model and data, and see no limit in their scaling laws!

    Noetik’s models can simulate how a patient will respond to experimental treatments. They are working with partners to test promising drugs that were demonstrated to be safe, but not effective. If these models work as hoped, Noetik will bring new cancer treatments to patients without developing a new drug! Their models will also guide the discovery process towards drugs that are more likely to make it through clinical trials. You can imagine why this is so attractive to GSK.

    We’ll see…

    Ron and Dan make pretty persuasive arguments that their models will truly assist in cohort selection in useful ways and this seems valuable. And we think it’s pretty clear that

    * Translation from lab to clinic is the biggest bottleneck for drug development.

    * Better cohort selection using biomarkers is likely to improve translation from lab to clinic.

    Noetik has already had some success here. We’ll see if they’re able to translate that into a reliable advantage.

    Stepping back a bit from the technology, curing cancer is a pretty unambiguously positive application of AI. It is also a very hard problem to solve. Our guess is that most people have been impacted by cancer or will be at some point soon. And we hope that learning about the amazing work that companies like Noetik are doing will inspire a generation of AI engineers to work on the hardest and most exciting problems that society faces.

    Full Video Pod:


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    Notion’s Token Town: 5 Rebuilds, 100+ Tools, MCP vs CLIs and the Software Factory Future — Simon Last & Sarah Sachs of Notion Apr 15, 2026
    Show notes

    For all those who missed out on London, see you in Miami next week!Notion, the knowledge work decacorn, has been building AI tooling since before ChatGPT, with many hits from Q&A in 2023 and unified AI in 2024 and Meeting Notes in 2025. At the end of their last Make user conference, Ryan Nystrom teased Notion 3.0’s Custom Agents - and they are finally embracing the Agent Lab playbook!Sarah Sachs and Simon Last of Notion join us for a deep dive into how Notion built Custom Agents, why it took years and multiple rebuilds to get right, and what it means to turn a productivity tool into an agent-native system of record for enterprise work.We go inside the product, engineering, evals, pricing, and org design decisions behind one of the most ambitious AI product efforts in software today — from early failed tool-calling experiments in 2022 to agent harnesses, progressive tool disclosure, meeting notes as data capture, and the long-term vision for software factories and agentic work.We discuss:* Sarah and Simon’s path to launching Notion Custom Agents, and why the feature was rebuilt four or five times before it was ready for production* Why early agent attempts failed: no tool-calling standard, short context windows, unreliable models, and too much complexity exposed to the model* The “Agent Lab” thesis: not just wrapping a model, but understanding how people collaborate and building the right product system around frontier capabilities* How Notion thinks about roadmap timing: not swimming upstream against model limitations, but also building early enough that the product is ready when the models are* Why coding agents feel like the kernel of AGI, and how Notion is thinking about “software factories” made up of agents that spec, code, test, debug, review, and maintain codebases together* How Sarah runs AI engineering at Notion (“notes from Token Town”): objective-setting over idea ownership, low-ego teams comfortable deleting their own work, and a culture designed to swarm around fast-changing opportunities* The “Simon Vortex,” company hackathons, and why security gets pulled in early rather than late* How Notion organizes AI: core AI capabilities and infrastructure, product packaging teams, and a broader company mandate that every product surface must increasingly work for both humans and agents* Why prototypes have become much easier to build internally, and how “demos over memos” changes product development inside a tool the whole company already uses every day* Notion’s eval philosophy: regression tests, launch-quality evals, and “frontier/headroom” evals that intentionally only pass ~30% of the time so the company can see where model capabilities are going* What a “Model Behavior Engineer” is, and why Notion treats eval writing, failure analysis, and model understanding as a distinct function rather than just software engineering* The changing role of software engineers in the age of coding agents, and why the new job looks less like typing code and more like supervising a rigorous outer system of agents, PRs, and verification loops* How the “software factory” should work: specs, self-verification, bug flows, subagents, and minimizing human intervention while preserving the invariants that matter* A live walkthrough of a Notion Custom Agent handling coworking space tenant applications by triaging email, enriching applicants with web search, and writing structured data into a Notion database* How agents compose inside Notion: shared databases as primitives, agents invoking other agents, “manager agents” supervising dozens of specialized agents, and memory implemented simply as pages and databases* Notion’s take on MCP vs CLI: why Simon is bullish on CLI’s self-debugging nature, where MCP still makes sense, and how Sarah thinks about capability, determinism, permissioning, and pricing alignment* The evolution of Notion’s internal agent harness: from early JavaScript coding agents, to custom XML, to Markdown and SQL-like abstractions, to tool definitions, progressive disclosure, and a much shorter system prompt* Why Notion cares about teaching “the top of the class,” building for sophisticated operators rather than abstracting away too much capability for everyone* How agent setup works today: agents that can configure themselves, inspect their own failures, and edit their own instructions — with guardrails around permissions* How Notion prices Custom Agents: credits as an abstraction over tokens, model type, serving tier, web search, and future sandbox costs; why usage-based pricing was necessary; and how “auto” tries to match the right model to the right task* Why Notion is not eager to train a foundation model, where they do fine-tune and optimize today, and why retrieval/ranking is one of the most important investment areas as more searches come from agents rather than humans* Why Meeting Notes became one of Notion’s strongest growth loops: not just as transcription, but as high-signal data capture that powers search, custom agents, follow-up workflows, and the broader system of record for company collaboration* Why Notion is more interested in being the place where collaboration data lives than in building hardware themselves — and how wearables or other capture devices may eventually feed into that systemSarah SachsLinkedIn: https://www.linkedin.com/in/sarahmsachsX: https://x.com/sarahmsachsSimon LastLinkedIn: https://www.linkedin.com/in/simon-last-41404140X: https://x.com/simonlastFull Video EpisodeTimestamps* 00:00:00 Introduction and launching Notion Custom Agents* 00:01:17 Why Notion rebuilt agents four or five times* 00:03:35 Building for where models are going, not just where they are* 00:05:32 The Agent Lab thesis, wrappers, and product intuition* 00:08:07 User journeys, leadership, and low-ego AI teams* 00:13:16 The Simon Vortex, hackathons, and bringing security in early* 00:16:39 Team structure, demos over memos, and building for agents* 00:20:25 Evals, Notion’s Last Exam, and the Model Behavior Engineer role* 00:27:37 Evals as an agent harness and the changing role of software engineers* 00:30:42 The software factory: specs, verification, and agent workflows* 00:32:18 Live demo: a custom agent for coworking space applications* 00:35:08 Composing agents, manager agents, and memory as pages* 00:38:15 Notion Mail, Gmail, native integrations, and tools* 00:39:43 MCP vs CLI and the cost of capability* 00:44:13 When Notion uses MCP vs building its own integrations* 00:47:43 The history of Notion’s agent harness rebuilds* 00:55:35 Power users, public tools, and the setup agent* 00:58:01 Self-fixing agents, permissions, and “flippy”* 01:01:13 Pricing, credits, and choosing the right model automatically* 01:09:01 Why Notion isn’t training its own frontier model* 01:14:07 Retrieval, ranking, and search built for agents* 01:17:27 Meeting Notes as data capture and workflow automation* 01:21:18 Wearables, hardware, and Notion as the system of record* 01:23:45 OutroTranscript[00:00:00] Alessio: Hey everyone. Welcome to the Latent Space podcast. This is Alessio founder of Kernel Labs and I’m joined by swyx, editor of the Latent Space.[00:00:11] swyx: Hello. Hello. We’re back in the beautiful studio that, uh, Alessio has set up for us with Simon and Sarah from Notion. Welcome.[00:00:18] Sarah Sachs: Thanks for having us.[00:00:19] Alessio: Thanks for having us. Yeah.[00:00:20] swyx: Congrats on the launch recently the custom agents, finally it’s here. How’s it feel?[00:00:26] Sarah Sachs: We ship things slowly. So it had been in Alpha for a little bit and at the point at which is it’s an alpha, um, there’s a group of people that are making sure it’s ready for prod, and then there’s a group of people working on the next thing.So sometimes some of these launches are a bit delayed satisfaction, so it’s quite nice to remind yourself all the work you did because we do have a habit of like. Being two or three milestones ahead. Uh, just ‘cause you have to be, you know, you can’t get complacent. Um, but it’s been great that people understood how this is helpful.And I think that’s just easier in general building AI tools today than it was two, three years ago. People kind of get it and so that user education, um, there’s just, it was our most successful launch in terms of free trials and converting people and things like that. It was really successful, so yeah.But there’s a lot to build.[00:01:12] swyx: Making it free for three months helps.[00:01:16] Sarah Sachs: Yep.[00:01:17] Simon Last: It was definitely super exciting for me because it’s probably the fourth or fifth time that we rebuilt that.[00:01:22] swyx: Yes.[00:01:23] Simon Last: And I mean,[00:01:24] swyx: you’ve been building this since like 20, 22.[00:01:26] Simon Last: Yeah, I mean, like, it was even right when we got access to like GPT four in late 20 22, 1 of the first ideas we had is like, oh, okay, let’s make an agent that I, we used the word assistant at the time, there wasn’t really the word, the word agent yet, but, oh, we’ll give an access to all the tools the notion can do, and then it, we run in the background like, like do work for us.And then we just tried that many times and it just. Was too early. Um,[00:01:48] swyx: I need to force you to like double click on that. What is too early? What didn’t work?[00:01:52] Sarah Sachs: We were fine to, like, before function calling came out. We were trying to fine tune with the Frontier Labs and with fireworks, like a function calling model on notion functions.This is right when I joined. I joined because, um, we needed a manager as Simon was needed to be able to go on vacation. So, uh, that’s, that’s around when I joined, so you can speak much more to it.[00:02:11] Simon Last: Yeah, we did partnerships with both philanthropic and open AI at different times, uh, to try to, at the time the, I mean, when we first tried, there wasn’t even a constant of like tools yet.We, we sort of designed our own like, like tool calling framework and then we tried to fine tune the models to, uh, to use it over multiple turns. Um, and because it, it didn’t work well out the box, I think. Yeah. The models are just too dumb and the context thing was also way too short.[00:02:37] Alsesio: Yeah.[00:02:37] Simon Last: Um, and yeah, we just kind of banged our head against it for a long time.Uh, unfortunately it was always like, there was always like sort of. Glimmers that it was working, but um, it never felt quite robust enough to be like a useful, delightful thing. Um, until I would say, uh, the big unlock was probably like Sonic 3.6 or seven, uh, early last year. And that’s when we started working on our agent, which we shipped last year.Um, and then, and then uh, uh, custom agents, kinda a similar capability and that, that one just took longer because we, we just wanted to get the reliability up a lot higher. ‘cause it’s actually running in the background.[00:03:14] Sarah Sachs: And the product interface of like permissions and understanding, you know, this custom agent is shared in a Slack channel with X group of people and has access to documents that are surfaced to Y group of people.And the intersect experts, Y might not be whole. And so how do you build the product around making sure administrators understand that permissioning took multiple swings.[00:03:35] Alsesio: Everything is hard back at the end of the day. Yeah. I’m curious, like when the models are not working, how do you inform the product roadmap of like, okay, we should probably build, expecting the models to be better at some reasonable pace, but at the same time we need to, you know, you had a lot of customers in 2022.It’s not like you were a new company or like no user base.[00:03:54] Simon Last: Yeah, I mean I think there’s always the balance of, you know, like you want to be a GI pilled and thinking ahead and building for where things are going. Uh, but also you wanna be like shipping useful things. And so we always try to like, like keep a balance there.You know, we. We try to take clear, like a portfolio approach. You know, we’re always working on multiple projects and, and we’re always trying to work on, you know, maintaining things where that have already shipped, like, like shipping new things that are like eminently working well and make them really good.And, and then we wanna always have a few projects that are a little bit crazy. Um,[00:04:23] Alsesio: and what are the a GI peel projects that you have today? I’m curious about, uh, you don’t have to share exactly what you’re working on, but I’m curious what are things today that maybe in 18 months people will be like, oh, obviously this was gonna work[00:04:35] Sarah Sachs: 18 months.[00:04:37] Alsesio: Yeah, 18 months is, you know,[00:04:37] Sarah Sachs: it’s a long time and Yeah. Yeah.[00:04:39] Simon Last: I mean, there’s a number of things happening. I think one thing that’s becoming more clear is I think like, like, uh, coding agents are the kernel of EGI, sort of, everything is a coding agent. Mm-hmm. I think that’s, that’s sort of one, one direction.Um, and then, yeah, the exciting thing about that is sort of your agent can sort of bootstrap its own software and capabilities and actually debug and maintain them. And so yeah, we’re, we’re, we’re thinking a lot about that. And then, yeah, like, like another category of things that I’m, I’m really excited about is like, uh, we call the software factory also.People are using this, uh, this, this sort of word. Um, basically it just means can you create sort of like a, as automated as possible, a workflow for developing debugging. Mm-hmm. Merging, reviewing, and maintaining a code base and a service where there’s a bunch of agents working together inside, and like, like how does that work?[00:05:28] Sarah Sachs: If you think back to your initial question, like, why did this take so long? I think something,[00:05:32] swyx: I didn’t say that, but Yes. Okay. Go ahead.[00:05:34] Sarah Sachs: Why, what, what changed over the three and half years of trying[00:05:37] swyx: it? Exactly. Right. Because most people always say like, it didn’t work yet. Then reasoning models came, then it worked.I was like, okay, let’s go a little[00:05:43] Sarah Sachs: bit. That’s, I mean, that’s part of it, but I think the other part of it that I actually think is really what will set notion apart for every new capability is we have like. Two skills that are crucial when it comes to frontier capabilities. One is not letting yourself swim upstream.So like quickly realizing if you’re just pressing against model capabilities versus not exposing the model to the right information, not having the right infrastructure set up. That and of itself is the skill of intuition. And the second is to see, okay, you’re not swimming upstream. Which direction is the river flowing and what is like, how do we think ahead about the product and start building it even if it’s not great yet, so that when it is there, we’re ready for it.Right? And like those can sometimes feel like counterintuitive things. Like we can be trying to fine tune a tool calling model when they don’t exist yet. And that the trick is to not do that for too long, but realize that there was something there. And we’ve had a lot of things which like, um, we’re just like not swimming in the right direction with the streams.I think we had multiple versions of transcription before we got meeting notes, right? Oh, I gotta talk[00:06:39] swyx: about that. Yeah.[00:06:40] Sarah Sachs: Yeah. Um, and so. I, I, I think that like we, we really closely partner with the Frontier Labs on capabilities and we also have to have strong conviction on, as those capabilities move.Notion is about being the best place for you to collaborate and do your work. And how does that narrative change if the way that we work changes?Yeah.[00:06:58] swyx: Yeah. You told me you were a fan of the Agent Lab thesis, and this is, this is k…

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    Extreme Harness Engineering for Token Billionaires: 1M LOC, 1B toks/day, 0% human code, 0% human review — Ryan Lopopolo, OpenAI Frontier & Symphony Apr 07, 2026
    Show notes

    We’re proud to release this ahead of Ryan’s keynote at AIE Europe. Hit the bell, get notified when it is live! Attendees: come prepped for Ryan’s AMA with Vibhu after.Move over, context engineering. Now it’s time for Harness engineering and the age of the token billionaires.Ryan Lopopolo of OpenAI is leading that charge, recently publishing a lengthy essay on Harness Eng that has become the talk of the town:In it, Ryan peeled back the curtains on how the recently announced OpenAI Frontier team have become OpenAI’s top Codex users, running a >1m LOC codebase with 0 human written code and, crucially for the Dark Factory fans, no human REVIEWED code before merge. Ryan is admirably evangelical about this, calling it borderline “negligent” if you aren’t using >1B tokens a day (roughly $2-3k/day in token spend based on market rates and caching assumptions):Over the past five months, they ran an extreme experiment: building and shipping an internal beta product with zero manually written code. Through the experiment, they adopted a different model of engineering work: when the agent failed, instead of prompting it better or to “try harder,” the team would look at “what capability, context, or structure is missing?”The result was Symphony, “a ghost library” and reference Elixir implementation (by Alex Kotliarskyi) that sets up a massive system of Codex agents all extensively prompted with the specificity of a proper PRD spec, but without full implementation:The future starts taking shape as one where coding agents stop being copilots and start becoming real teammates anyone can use and Codex is doubling down on that mission with their Superbowl messaging of “you can just build things”.Across Codex, internal observability stacks, and the multi-agent orchestration system his team calls Symphony, Ryan has been pushing what happens when you optimize an entire codebase, workflow, and organization around agent legibility instead of human habit.We sat down with Ryan to dig into how OpenAI’s internal teams actually use Codex, why the real bottleneck in AI-native software development is now human attention rather than tokens, how fast build loops, observability, specs, and skills let agents operate autonomously, why software increasingly needs to be written for the model as much as for the engineer, and how Frontier points toward a future where agents can safely do economically valuable work across the enterprise.We discuss:* Ryan’s background from Snowflake, Brex, Stripe, and Citadel to OpenAI Frontier Product Exploration, where he works on new product development for deploying agents safely at enterprise scale* The origin of “harness engineering” and the constraint that kicked off the whole experiment: Ryan deliberately refused to write code himself so the agent had to do the job end to end* Building an internal product over five months with zero lines of human-written code, more than a million lines in the repo, and thousands of PRs across multiple Codex model generations* Why early Codex was painfully slow at first, and how the team learned to decompose tasks, build better primitives, and gradually turn the agent into a much faster engineer than any individual human* The obsession with fast build times: why one minute became the upper bound for the inner loop, and how the team repeatedly retooled the build system to keep agents productive* Why humans became the bottleneck, and how Ryan’s team shifted from reviewing code directly to building systems, observability, and context that let agents review, fix, and merge work autonomously* Skills, docs, tests, markdown trackers, and quality scores as ways of encoding engineering taste and non-functional requirements directly into context the agent can use* The shift from predefined scaffolds to reasoning-model-led workflows, where the harness becomes the box and the model chooses how to proceed* Symphony, OpenAI’s internal Elixir-based orchestration layer for spinning up, supervising, reworking, and coordinating large numbers of coding agents across tickets and repos* Why code is increasingly disposable, why worktrees and merge conflicts matter less when agents can resolve them, and what it really means to fully delegate the PR lifecycle* “Ghost libraries”, spec-driven software, and the idea that a coding agent can reproduce complex systems from a high-fidelity specification rather than shared source code* The broader future of Frontier: safely deploying observable, governable agents into enterprises, and building the collaboration, security, and control layers needed for real-world agentic workRyan Lopopolo* X: https://x.com/_lopopolo* Linkedin: https://www.linkedin.com/in/ryanlopopolo/* Website: https://hyperbo.la/contact/Timestamps00:00:00 Introduction: Harness Engineering and OpenAI Frontier00:02:20 Ryan’s background and the “no human-written code” experiment00:08:48 Humans as the bottleneck: systems thinking, observability, and agent workflows00:12:24 Skills, scaffolds, and encoding engineering taste into context00:17:17 What humans still do, what agents already own, and why software must be agent-legible00:24:27 Delegating the PR lifecycle: worktrees, merge conflicts, and non-functional requirements00:31:57 Spec-driven software, “ghost libraries,” and the path to Symphony00:35:20 Symphony: orchestrating large numbers of coding agents00:43:42 Skill distillation, self-improving workflows, and team-wide learning00:50:04 CLI design, policy layers, and building token-efficient tools for agents00:59:43 What current models still struggle with: zero-to-one products and gnarly refactors01:02:05 Frontier’s vision for enterprise AI deployment01:08:15 Culture, humor, and teaching agents how the company works01:12:29 Harness vs. training, Codex model progress, and “you can just do things”01:15:09 Bellevue, hiring, and OpenAI’s expansion beyond San FranciscoTranscriptRyan Lopopolo: I do think that there is an interesting space to explore here with Codex, the harness, as part of building AI products, right? There’s a ton of momentum around getting the models to be good at coding. We’ve seen big leaps in like the task complexity with each incremental model release where if you can figure out how to collapse a product that you’re trying to.Build a user journey that you’re trying to solve into code. It’s pretty natural to use the Codex Harness to solve that problem for you. It’s done all the wiring and lets you just communicate in prompts. To let the model cook, you have to step back, right? Like you need to take a systems thinking mindset to things and constantly be asking, where is the Asian making mistakes?Where am I spending my time? How can I not spend that time going forward? And then build confidence in the automation that I’m putting in place. So I have solved this part of the SDLC.swyx: [00:01:00] All right.[00:01:03] Meet Ryan swyx: We’re in the studio with Ryan from OpenAI. Welcome.Ryan Lopopolo: Hi,swyx: Thanks for visiting San Francisco and thanks for spending some time with us.Ryan Lopopolo: Yeah, thank you. I’m super excited to be here.swyx: You wrote a blockbuster article on harness engineering. It’s probably going to be the defining piece of this emerging discipline, huh?Ryan Lopopolo: Thank you. It is it’s been fun to feel like we’ve defined the discourse in some sense.swyx: Let’s contextualize a little bit, this first podcast you’ve ever done. Yes. And thank you for spending with us. What is, where is this coming from? What team are you in all that jazz?Ryan Lopopolo: Sure, sure.Ryan Lopopolo: I work on Frontier Product Exploration, new product development in the space of OpenAI Frontier, which is our enterprise platform for deploying agents safely at scale, with good governance in any business. And. The role of VMI team has been to figure out novel ways to deploy our models into package and products that we can sell as solutions to enterprises.swyx: And you have a background, I’ll just squeeze it in there. Snowflake, brick, [00:02:00] stripe, citadel.Ryan Lopopolo: Yes. Yes. Same. Any kind of customerswyx: entire life. Yes. The exact kind of customer that you want to,Vibhu: so I’ll say, I was actually, I didn’t expect the background when I looked at your Twitter, I’m seeing the opposite.Stuff like this. So you’ve got the mindset of like full send AI, coding stuff about slop, like buckling in your laptop on your Waymo’s. Yes. And then I look at your profile, I’m like, oh, you’re just like, you’re in the other end too. Oh, perfect. Makes perfect.Ryan Lopopolo: I it’s quite fun to be AI maximalist if you’re gonna live that persona.Open eye is the place to do it. And it’sswyx: token is what you say.Ryan Lopopolo: Yeah. Certainly helps that we have no rate limits internally. And I can go, like you said, full send at this stay.swyx: Yeah. Yeah. So the Frontier, and you’re a special team within O Frontier.Ryan Lopopolo: We had been given some space to cook, which has been super, super exciting.[00:02:47] Zero Code ExperimentRyan Lopopolo: And this is why I started with kind of a out there constraint to not write any of the code myself. I was figuring if we’re trying to make agents that can be deployed into end to enterprises, they should be [00:03:00] able to do all the things that I do. And having worked with these coding models, these coding harnesses over 6, 7, 8 months, I do feel like the models are there enough, the harnesses are there enough where they’re isomorphic to me in capability and the ability to do the job.So starting with this constraint of I can’t write the code meant that the only way I could do my job was to get the agent to do my job.Vibhu: And like a, just a bit of background before that. This is basically the article. So what you guys did is five months of working on an internal tool, zero lines of code over a mi, a million lines of code in the total code base.You say it was cenex, more like it was cenex faster than you would’ve. If you had done it by end. SoRyan Lopopolo: yeah, thatVibhu: was the mindset going into this, right?Ryan Lopopolo: That’s right.[00:03:46] Model Upgrades LessonsRyan Lopopolo: Started with some of the very first versions of Codex CLI, with the Codex Mini model, which was obviously much less capable than the ones we have today.Which was also a very good constraint, right? Quite a visceral feeling to ask the [00:04:00] model to build you a product feature. And it just not being able to assemble the pieces together.Which kind of defined one of the mindsets we had for going into this, which is whenever the model just cannot, you always pop open at the task, double click into it, and build smaller building blocks that then you can reassemble into the broader objective.And it was quite painful to do this. Honestly, the first month and a half was. 10 times slower than I would be. But because we paid that cost, we ended up getting to something much more productive than any one engineer could be because we built the tools, the assembly station for the agent to do the whole thing.[00:04:43] Model Generations, Build Systems & Background ShellsRyan Lopopolo: But yeah, so onward to G BT 5, 5, 1, 5, 2, 5, 3, 5 4. To go through all these model generations and see their kind of corks and different working styles also meant we had to adapt the code base to change things up when the model was revved. [00:05:00] One interesting thing here is five two, the Codex harness at the time did not have background shells in it, which means we were able to rely on blocking scripts to perform long horizon work.But with five, three and background shells, it became less patient, less willing to block. So we had to retool the entire build system to complete in under a minute and. This is not a thing I would expect to be able to do in a code base where people have opinions. But because the only goal was to make the Asian productive over the course of a week, we went from a bespoke make file build to Basil, to turbo to nx and just left it there because builds were fast at that point.swyx: Interesting. Talk more about Turbo TenX. That’s interesting ‘cause that’s the other direction that other people have been doing.Ryan Lopopolo: Ultimately I have. Not a lot of experience with actual frontend repo architecture.swyx: You’re talking that Jessica built the sky. So I’m like, I know the NX team. I know Turbo from Jared [00:06:00] Palmer.And I’m like, yeah, that’s an interesting comparison.[00:06:02] One Minute Build LoopRyan Lopopolo: The hill we were climbing right, was make it fast.swyx: Is there a micro front end involved? Is it how how complex reactRyan Lopopolo: electron base single app sort of thingswyx: And must be under a minute. That’s an interesting limitation. I’m actually not super familiar with the background shelf stuff.Probably was talked about in the fight three release.Ryan Lopopolo: BA basically means that codex is able to spawn commands in the background and then go continue to work while it waits for them to finish. So it can spawn an expensive build and then continue reviewing the code, for example.swyx: Yeah.Ryan Lopopolo: And this helps it be more time efficient for the user invoking the harness.swyx: And I guess and just to really nail this, like what does one minute matter? Like why not five, okay, good. We want no. WeRyan Lopopolo: want the inner loop to be as fast as possible. Okay. One minute was just a nice round number and we were able to hit it.swyx: And if it doesn’t complete, it kills it or some something,Ryan Lopopolo: No.We just take that as a signal that we need to stop what we’re doing, double click, decompose a build graph a bit to get us to high back under so that we [00:07:00] can able the agent continue to operate.swyx: It’s almost like you’re, it’s like a ratchet. It’s like you’re forcing build time discipline, because if you don’t, it’ll just grow and grow.That’s right. And you mentioned that my current, like the software I work on currently is at 12 minutes. It sucks.Ryan Lopopolo: This has been my experience with platform teams in the past, where you have an envelope of acceptable build times and you let it go up to breach and then you spend two, three weeks to bring it back down to the lower end of the average low bed stop.But because tokens are so cheap Yeah. And we’re so insanely parallel with the model, we can just constantly be gardening this thing to make sure that we maintain these in variants, which means. There’s way less dispersion in the code and the SDLC, which means we can simplify in a way and rely on a lot more in variance as we write the software.[00:07:45] Observability, Traces & Local Dev StackVibhu: Lovely.[00:07:46] Humans Are BottleneckVibhu: You mentioned in your article, like humans became the bottleneck, right? You kicked off as a team of three people. You’re putting out a million line of code, like 1500 prs, basically. What’s the mindset there? So as much as code is disposable, you’re doing a lot of review. A lot [00:08:00] of the article talks about how you wanna rephrase everything is prompting everything, is what the agent can’t see.It’s kind of garbage, right? You shouldn’t have it in there. So what’s like the high level of how you went about building it, and then how you address okay, humans are just PR review. Like how is human in the loop for this?Ryan Lopopolo: We’ve moved beyond even the humans reviewing the code as well.[00:08:19] Human Review, PR Automation & Agent Code ReviewRyan Lopopolo: Most of the human review is post merge at this point.But post, post merge, that’s not even reviewed. That’s justswyx: Oh, let’s just make ourselves happy by YouRyan Lopopolo: haven’t used fundamentally. The model is trivially paralyzable, right? As many GPUs and tokens as I am willing to spend, I can have capacity to work with my hood base.The only fundamentally scarce thing is the synchronous human attention of my team. There’s only so many hours in the day we have to e…

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    Marc Andreessen introspects on The Death of the Browser, Pi + OpenClaw, and Why "This Time Is Different" Apr 03, 2026
    Show notes

    Fresh off raising a monster $15B, Marc Andreessen has lived through multiple computing platform shifts firsthand, from Mosaic and Netscape to cofounding A16z. In this episode, Marc joins swyx and Alessio in a16z’s legendary Sand Hill Road office to argue that AI is not just another hype cycle, but the payoff of an “80-year overnight success”: from neural nets and expert systems to transformers, reasoning models, coding, agents, and recursive self-improvement. He lays out why he thinks this moment is different, why AI is finally escaping the old boom-bust pattern, and why the real bottleneck may be less about models than about the messy institutions, incentives, and social systems that struggle to absorb technological change.This episode was a dream come true for us, and many thanks to Erik Torenberg for the assist in setting this up. Full episode on YouTube!We discuss:* Marc’s long view on AI: from the 1980s AI boom and expert systems to AlexNet, transformers, and why he sees today’s moment as the culmination of decades of compounding technical progress* Why “this time is different”: the jump from LLMs to reasoning, coding, agents, and recursive self-improvement, and why Marc thinks these breakthroughs make AI real in a way prior cycles were not* AI winters vs. “80-year overnight success”: why the field repeatedly swings between utopianism and doom, and why Marc thinks the underlying researchers were mostly right even when the timelines were wrong* Scaling laws, Moore’s Law, and what to build: why he believes AI scaling laws will continue, why the outside world is messier than lab purists assume, and how startups can still create durable value on top of rapidly improving models* The dot-com crash and AI infrastructure risk: Marc’s comparison between today’s AI capex boom and the fiber/data-center overbuild of 2000, plus why he thinks this cycle is different because the buyers are huge cash-rich incumbents and demand is already here* Why old NVIDIA chips may be getting more valuable: the pace of software progress, chronic capacity shortages, and the idea that even current models are “sandbagged” by supply constraints* Open source, edge inference, and the chip bottleneck: why Marc thinks local models, Apple Silicon, privacy, trust, and economics all point toward a major role for edge AI* American vs. Chinese open source AI: DeepSeek as a “gift to the world,” why open models matter not just because they’re free but because they teach the world how things work, and how open source strategies may shift as the market consolidates* Why Pi and OpenClaw matter so much: Marc’s claim that the combination of LLM + shell + filesystem + markdown + cron loop is one of the biggest software architecture breakthroughs in decades* Agents as the new “Unix”: how agent state living in files allows portability across models and runtimes, and why self-modifying agents that can extend themselves may redefine what software even is* The future of coding and programming languages: why Marc thinks software becomes abundant, why bots may translate freely across languages, and why “programming language” itself may stop being a salient concept* Browsers, protocols, and human readability: lessons from Mosaic and the web, why text protocols and “view source” mattered, and how similar principles may shape AI-native systems* Real-world OpenClaw use: health dashboards, sleep monitoring, smart homes, rewriting firmware on robot dogs, and why the most aggressive users are discovering both the power and danger of agents first* Proof of human vs. proof of bot: why Marc thinks the internet’s bot problem is now unsolvable via detection alone, and why biometric + cryptographic proof of human becomes necessaryTimestamps* 00:00 Marc on AI’s “80-Year Overnight Success”* 00:01 A Quick Message From swyx* 01:44 Inside a16z With Marc Andreessen* 02:13 The Truth About a16z’s AI Pivot* 03:29 Why This AI Boom Is Not Like 2016* 06:33 Marc on AI Winters, Hype Cycles, and What’s Different Now* 10:09 Reasoning, Coding, Agents, and the New AI Breakthroughs* 12:13 What Founders Should Build as Models Keep Improving* 16:33 AI Capex, GPU Shortages, and the Dot-Com Crash Analogy* 24:54 Open Source AI, Edge Inference, and Why It Matters* 33:03 Why OpenClaw and PI Could Change Software Forever* 41:37 Agents, the End of Interfaces, and Software for Bots* 46:47 Do Programming Languages Even Have a Future?* 54:19 AI Agents Need Money: Payments, Crypto, and Stablecoins* 56:59 Proof of Human, Internet Bots, and the Drone Problem* 01:06:12 AI, Management, and the Return of Founder-Led Companies* 01:12:23 Why the Real Economy May Resist AI Longer Than Expected* 01:15:53 Closing ThoughtsTranscriptMarc: Something about AI that causes the people in the field, I would say, to become both excessively utopian and excessively apocalyptic. Having said that, I think what’s actually happened is an enormous amount of technical progress that built up over time. And like for, for example, we now know that neural network is the correct architecture.And I, I will tell you like there was a 60 year run where that was like a, you know, or even 70 years where that was controversial. And so, so the way I think about what’s happening is basically, I think, I think about basically the, the, the period we’re in right now is it’s, I call it 80 year overnight success, right?Which is like, it’s an overnight success ‘cause it’s like bam, you know, chat GPT hits and then, and then oh one hits, and then, you know, open claw hits and like, you know, these are open, these are, these are like overnight, like radical, overnight transformative successes, but they’re drawing on an 80 year sort of wellspring backlog, you know, of, of, of, of ideas and thinking it’s not just that it’s all brand new, it’s that it’s an unlock of all of these decades of like very serious, hardcore research.If I were 18, like this is a hundred, this is what I would be spending all of my time on. This is like such an incredible conceptual breakthrough.swyx: Before we get into today’s episode, I just have a small message for listeners. Thank you. We will not be able to bring you the ai, engineering, science, and entertainment contents that you so clearly want if you didn’t choose to also click in and tune into our content.We’ve been approached by sponsors on an almost daily basis, but fortunately enough of you actually subscribed to us to keep all this sustainable without ads, and we wanna keep it that way. But I just have one favor to ask all of you. The single, most powerful, completely free thing you can do is to click that subscribe button.It’s the only thing I’ll ever ask of you, and it means absolutely everything to me and my team that works so hard to bring the in space to you each and every week. If you do it, I promise you will never stop working to make the show even better. Now, let’s get into it.Alessio: Hey everyone, welcome to the Lidian Space Pockets. This is CIO, founder Kernel Labs, and I’m joined by s Swix, editor of Lidian Space.swyx: Hello. And we’re in a 16 Z with a, uh, mark G and welcome.Marc: Yes, yes. A and what, half of 16? Something like that. A one. Exactly,swyx: exactly. Uh, apparently this is the, the final few days in your, your current office.You’re moving across the road.Marc: Uh, we’re, yeah. We have a, we have some, we have some projects underway, but yeah, this is actually, oh, this is the original. We’re in actually the original office. We’re in the, we’re in the, we’re, we’re in the whole thing.swyx: It’s beautiful. Yeah. Great.Marc: Thank you.swyx: So I have to come out, uh, this is a, you know, I wanted to pick a spicy start in October, 2022.I just made friends with Roone and, uh, I wanted to give him something to sort of be spicy about. And I said, uh. Uh, it’ll never not be funny. The A 16 Z was constantly going. The future is where the smart people choose to spend their time and then going deep into crypto and not in ai. And that was in October 22nd, 2022.And Ruen says there was an internal meeting in a 16 Z to reorient around Gen ai. Obviously you have, but was there a meeting? What, what was that?Marc: I mean, I don’t, look, I’ve been doing AI since the late eighties.swyx: Yeah.Marc: So I, I don’t know, like all that, as far as I’m concerned, this stuff is all Johnny cum lately.Yeah. You, I mean, look, we’ve been doing ar entire existence. I mean, we’ve been doing AI machine learning deep, you know, deeply. We’ve been doing this stuff way from the beginning. Obviously a AI is just core to computer science. I, I, I actually view them as like quite, uh, quite continuous. Um, you know, Ben and I both have computer science degrees.Um, you know, we, we both, Ben, Ben and I actually both are world enough to remember the actual AI boom in the 1980s. Yeah. There was like a, there was a big AI boom at the time. Um, and there was a, was names like expert systems. Um, and they of like lisp and lisp machines. Uh, I, I coded in lisp. I was coding a lisp in 1989.When that was the, the language of the AI future. Um, yeah. So this is something that we’re like completely, you completely comfortable with. I’ve been doing the whole time and are very enthusiastic aboutswyx: is there a strong, like this time is different because, uh, my closest analog was 20 16 17. It was an AI boom.Mm-hmm. And it petered out very, very quickly. Um, we, it just, it just in terms of investingMarc: sort of, sort of,swyx: yeah. Investment, investment excitement.Marc: Although that’s really when the, the, the Nvidia phenomenon really, it was, I would say it was in that period when it was very clear that at, at the time it, the vocabulary was more machine learning, but it, it was very clear at that time that machine learning was hitting some sort of takeoff point.Alessio: Yeah.Marc: Well, and as you guys, you guys have talked about this at length on, on your thing, but, you know, if you really track what happened, I think the real story is, it was, it was the Alex net, uh, basically breakthrough in like 2013. That was the, that was the real knee in the curve. Um, and then it was obviously the transformer breakthrough in 17.Alessio: Yeah.Marc: Um, and then everything that followed. But, but, you know, look, machine learning, you know, there were, you know, look, uh, I mean look, I’ve been working, you know, I’ve been working with, uh, one of my, you know, kind of projects working with Facebook since 2004. Um, and on the board since 2007, and of course, you know, they, they started using machine learning very early, um, and, you know, have used it basically, you know, for like 20 years for, you know, content, you know, feed optimization and advertising optimization.And obviously many, you know, financial services. You know, many, many, many companies, many different sectors have been doing this. And so it’s like one of these things, it’s like, it’s not a, it’s not a single thing. Like it’s, it’s like, it’s like layers, right? Yeah. Um, and, and the layers arrive at different paces and, but they kind of build up.swyx: Yeah.Marc: Uh, they kind of build up over time and then, and then, yeah. And then look, in retrospect, it was 2017 was kind of the, you know, the key, the key point with the trans transformer and then. And then as you guys know, there was this really weird like four year period where it’s like the, the transformer existed and then it was just like,swyx: let’s go.Yeah.Marc: Well, but, but it was just, but, but between 2020, but between 2017 and 2021, I mean, that was the era of which like companies like Google had internal chat Botts, but they weren’t letting anybody use them.swyx: Yeah.Marc: Right. And then, you know, and then OpenAI developed Chat GT or GPT two, and then they told everybody, this is way too dangerous to deploy.Right. Yeah. You know, we can’t possibly let normal people, normal people use this thing. And then you, you guys, I’m sure remember AI Dungeon, um mm-hmm. So the o for, there was like a year where like the only way for a normal person to use GP T three was in, in AI dungeon.Alessio: Yeah.Marc: And so you, you, we would do this, you’d go in there and you’d pretend to play Dungeons and Dragons.In reality, you’re just trying to talk to talk to GPT. And so there was this, you know, there was this long, you know, and I, you know, the big, big companies, you know, big companies are cautious and, you know, the big companies were cautious. It, it, by the way, it took open ai. You know, they, they, they talk about this, it took open AI time to actually adjust, you know, kind of re redirect their researchswyx: path.I, I think, uh, let say Rosewood, right? Uh, the, the dinner that founded OpenAI was right there.Marc: Right, right. But that, that dinner would’ve taken place in 20swyx: 18Marc: 19. The formation of OpenAI Uhhuh as late as 2018.swyx: Uh, uh, sorry. Uh, no, I’m, I’m, I’m, I’m wrong. Probably It should be 20. Yeah. They just celebrated a 10 year anniversary, so it it is 2025.Yeah, so, so 2015?Marc: Yeah. 2015. Yeah. 2015. But then, uh, um, Alec Radford did G PT one in what, probablyswyx: mm-hmm. 17, 18,Marc: yeah. 17, 18. So it, yeah. For, and then, and then they didn’t really, and then GPT three was what? 2020? 2020.swyx: 2020.Marc: Because that became copilot immediately. Even open ai, which has been, you know, the leader of, of this thing in the last decade, you know, e even they had to adapt and, and, and lean into the new thing.And so. Um, yeah, I, I think it’s just this process of basically sort of wave after wave layer after layer, you know, building on itself. And then you kind of get these catalytic moments where, where the whole thing pops and, and obviously that’s what’s happening now.swyx: Is it useful to think about will there be any ai, winter?‘cause there’s always these patterns. Like, is this, in the summer is something I constantly think about because do I get, do I just like. Just get endlessly hyped and just trust that I will only be early and never wrong or right. Well, are we, will there be a winter?Marc: So there’s something about, say the following.There’s something about AI that has led to this repeated pattern. Um, and, and, and you guys know this,swyx: it’s summer, winter, summer,Marc: winter, summer, winter, summer, winter. And it goes back 80 years. Yeah. 80 years. Uh, so the original neural network paper was 1943. Right. Which is, which is amazing. Uh, that it was, it was far back that long.And then there was you, if you guys have ever talked about this on your show, but there was this, uh, there was a big, uh, there was an a GI conference at Dartmouth University in 1950. 55. 55, yeah. And they got a NSF grant to, uh, for the, all the AI experts at the time to spend the summer together. And they figured if they had 10 weeks together, they could get a GI, uh, at the other end.And they got their, by the way, they got the grant, they got the 10 weeks and then, you know, 1955, you know. No, no. A GI. And like I said, I, I lived through the eighties version of this where there was a big, a big boom and a crash. And so, so there is this thing, and there, there is something about AI that causes the people in the field, I would say, to become both excessively utopian and excessively apocalyptic.Um, and, and it’s probably on both sides of like the, the, the boom bus cycle. You, you kind of see that play out. Having said that, I think what’s actually happened is like just, and you know, and we now know in retrospect like an enormous amount of technical progress that built up over time. And like for, for example, we now know that neural network is the correct architecture.And I, I will tell you like there was a 60 year run where that was like a, you know, or even 70 years or that was controversial. And, and we now know that that’s the case. And so we, we now, you know, everything we’re building on today just sort of derives from the original idea in 1943. And so, so…

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    Moonlake: Causal World Models should be Multimodal, Interactive, and Efficient — with Chris Manning and Fan-yun Sun Apr 02, 2026
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    We’ve been on a bit of a mini World Models series over the last quarter: from introducing the topic with Yi Tay, to exploring Marble with World Labs’ Fei-Fei Li and Justin Johnson, to previewing World Models learned from massive gaming datasets with General Intuition’s Pim de Witte (who has now written down their approach to World Models with Not Boring), to discussing the Cosmos World Model with with Andrew White of Edison Scientific on our new Science pod, to writing up our own theses on Adversarial World Models. Meanwhile Nvidia, Waymo and Tesla have published their own approaches, Google has released Genie 3, and Yann LeCun has raised $1B for AMI and published LeWorldModel.Today’s guests have a radically different approach to World Modeling to every player we just mentioned — while Genie 3 is impressive, its many flaws demonstrate the issues with their approach - terrain clipping, noninteractivity (single player, no physics/no objects other than the player move), and maximum of 60 second immersion. Moonlake AI (inspired by the Dreamworks logo) is the diametric opposite - immediately multiplayer, incredibly interactive, indefinite lifetime, capable of MANY different kinds of world models by simulating environments, predicting outcomes, and planning over long horizons. This is enabled by bootstrapping from game engines and training custom agents: In Towards Efficient World Models, Chris Manning and Ian Goodfellow join Fan-Yun in explaining why their approach to efficiency with structure and casuality instead of just blind scaling is sorely needed:SOTA models still show physical or spatial understanding glitches, such as solid objects floating in mid-air or moving “inside” other solid objects.If the goal is to plan for the next action, how often is a high-resolution pixel view necessary for modeling the world? Our bet is that there is a disproportionately large share of economically valuable tasks where such detail is not required. After all, humans with a wide variety of sensory limitations have little difficulty doing almost everything in the world. Furthermore, for a large number of purposes, describing a scene or a situation in a few words of language (“the car’s tires squealed as it cornered sharply”) is sufficient for understanding and planning.Experiments also show that humans only partially process visual input in a top-down, task-directed way, often making use of abstracted object-level modeling. In almost all cases, partial representations combined with semantic understanding are sufficient.…If the goal is to facilitate the understanding of causality in multimodal environments, then the world model—whether it is used in the virtual world or the physical world—must prioritize properties such as spatial and physical state consistency maintained over long time periods, and an ability to evolve the world that accurately reflects the consequences of actions. That’s what Moonlake is building.Game engines are the right starting point abstraction to efficiently extract causal relationships, and building the interfaces and community (including their new $30,000 Creator Cup) to kickstart the flywheel of actions-to-observations.We were fortunate enough to attend their sessions at GDC 2026 (the Mecca of Game Devs), and were impressed by the huge variety and flexibility of the worlds people were building with Moonlake’s tools already! Live videos on the pod.Full Video Pod on YouTube!Timestamps00:00 Benchmarking Gets Hard00:47 Meet Moonlake Founders01:26 Why Build World Models03:12 Structure Not Just Scale05:37 Defining Action Conditioned Worlds07:32 Abstraction Versus Bitter Lesson14:39 Language Versus JEPA Debate20:27 Reasoning Traces And Rendering Layer37:00 Gameplay Over Graphics38:02 Fiction Rules And World Tweaks39:15 Code Engines Beat Learned Priors41:10 Diffusion Scaling Limits43:23 Symbolic Versus Diffusion Boundary46:14 Platform Vision Beyond Games50:24 Spatial Audio And Multimodal Latents54:23 NLP Roots Hiring And Moon Lake NameTranscript[00:00:00] Cold Open[00:00:00] Chris Manning: Think this whole space is extremely difficult as things are emerging now. And I mean, it’s not only for world models, I think it’s for everything including text-based models, right? ‘cause in the early days it seemed very easy to have good benchmarks ‘cause we could do things like question answering benchmarks.[00:00:20] But these days so much of what people are wanting to do is nothing like that, right? You’re wanting to get some recommendations about which backpack would be best for you for your trip in Europe next month. It’s not so easy to come up with a benchmark, and it’s the same problem with these world models.[00:00:41] Meet the Founders[00:00:41] swyx: Okay. We’re back in the studio with Moon Lake’s, two leads. I, I guess there’s other founders as well, but, sun and Chris Manning. Welcome to the studio.[00:00:54] Fan-yun Sun: Thanks. Thanks, Chris. Thanks for having us.[00:00:56] swyx: You’ve got, you guys have, come burst onto the scene with a really refreshing [00:01:00] new take of mold models.[00:01:01] I would just want to, I guess ask how you, the two of you came together. Chris, you’re a legend in NLP and just AI in, in, in general. You’re, you’re his grad student, I guess[00:01:10] Fan-yun Sun: Actually my co-founder.[00:01:11] swyx: Oh, yeah.[00:01:12] Fan-yun Sun: I should give a lot of credit to my co-founder, Sharon. Yeah. She was, she was actually working with Professor Fe Androgyn and then she ended up working with, Ron and Chris Manning here.[00:01:22] And then, so I got connected through to Chris initially, actually through my co-founder,[00:01:26] What is Moon Lake?[00:01:26] swyx: what is Moon Lake? What, what is, actually, I’m also very curious about the name, but like why going into world models?[00:01:33] Fan-yun Sun: So I was working a lot. With actually Nvidia research during my PhD years on essentially generating interactive worlds to train reinforcement learning agents or embody EA agents.[00:01:44] And then there’s two observations. One in academia and one in industry. An industry like folks at Nvidia are actually paying a lot of dollars to purchase these types of interactive worlds, whether it’s for the sake of evaluation or training the robots, or policies or models. And [00:02:00] then, in academia, same thing is happening.[00:02:02] And more specifically, when I was actually working with Nvidia on the synthetic data foundation model training project, we were actually generating a lot of these synthetic data and showing that, hey, you can actually, these synthetic data are actually as useful as real world data when it comes to multimodal pre-training.[00:02:16] But then, like I said, there’s a lot of dollars being paid out to like external vendors or, or like. Other folks to manually curate these types of data. It was very clear to us that, okay, on our way to, let’s call it embody general intelligence models need to learn the consequences behind their actions, which means that they need interactive data and the demand for those types of data are growing exponentially.[00:02:38] But everybody’s sort of thinking about it from a pure, say, video generation perspective or something else. But we feel like the true actually opportunity is actually building reasoning models that can do these things, like how humans do these things today. So that’s a little bit on the genesis of Moon Lake, and I think the reason I got into world models was partly.[00:02:59] A philosophical [00:03:00] take of the on the world where I like, believe the simulation theory and stuff like that. But on the other, on the other hand, it’s really just like, oh, like there’s an opportunity there that I feel like nobody’s doing it the way I think should be done.[00:03:10] Structure, Not Scale: The Vision[00:03:10] Chris Manning: I can say a little bit about that.[00:03:12] Yeah. So of the overall goal is the pursuit of artificial intelligence and most of my career has been doing that in the language space and that’s been just extremely productive. As we all know, the story of the last few years, I don’t have to tell about how much we’ve achieved with large language models, but, uh.[00:03:31] Although they have been extremely effective for ramping language and general intelligence, it’s clearly not the whole world. There’s this multimodal world of vision, sound, taste that you’d like to be dealing with more than just, language. And then the question is how to do it. And despite, a huge investment in the computer vision space, right, as the research field computer [00:04:00] vision has been for decades, far, far larger than the language space, actually.[00:04:05] I think it’s fair. Say that, vision, understanding sort of stalled out, right? You got to object recognition and then progress just wasn’t being made right? If you look at any of these, vision language models, it’s the language that’s doing 90% of the work and the vision barely works. And so there’s really an interesting research question as to why that is and at heart, the ideas behind Moon Lake are an attempt to answer that, believing that there can be a really rich connection between a more symbolic layer of abstracted understanding of visual domains, which aren’t in the mainstream vision models, which are still trying to operate on the surface level of pixels.[00:04:50] swyx: I think one of your blog posts, you put it as structure, not scale. Is that, a general thesis?[00:04:57] Chris Manning: Yeah. Well, scale is good too.[00:04:58] swyx: Yeah. Scale is good. Too[00:04:59] lot,[00:04:59] Chris Manning: [00:05:00] lots of data is good as well and scale, but nevertheless, you want the structure Yeah. To be able to much more efficiently learn.[00:05:07] swyx: Yeah. The other thing I really liked also is you put out an example of what your kind of reasoning traces look like.[00:05:12] Right. Which you would distill is the word that comes to mind. I don’t even think that’s a good, good description, but it would involve, for example, geometry, physics, affordances, symbolic logic, perceptual mappings, and what, what have you. But like that, that is the kind of example that involves, let’s call it spatial reasoning, role model reasoning as as compared to normal LM reasoning.[00:05:35] Yeah.[00:05:36] Defining World Models vs Video Generation[00:05:36] Vibhu: But also like taking it a step back. So how do you guys define world models? A lot of people see okay, you can do diffusion, you can do video generation. But, you guys put out quite a few blog posts. You put out a essay recently, we can even pull it up about efficient world models. You have a pretty like structural definition here, but for the general audience that don’t super follow the space, right.[00:05:55] What’s, what’s the difference in what we see from like a video generation model to [00:06:00] a world gen A simulator? How do you kind of paint that last[00:06:02] Chris Manning: year? Yeah, so I think this is actually a little bit subtle because, people look at these amazing generative AI video models, SAWA VO three, one of these things, and they think Genie, they think, oh, this is amazing.[00:06:17] This is we’ve solved understanding the world because you can produce these generative AI videos, but. The reality is that although the visuals do look fantastic, those visuals actually are accompanied by an understanding of the 3D world, understanding how objects can move, what the consequences of different actions are, and that’s what’s really needed for spatial intelligence.[00:06:49] So I mean, a term we sometimes use is that you need action condition, world models. That you only actually have a world model if you can predict, [00:07:00] given some action is taken, what is going to change in the world because of it. And in particular, that becomes hard over longer time scales. So if you’re simply, trying to.[00:07:12] Predict the next video frame. That’s not so difficult. But what you actually want to do is understand the consequences, likely consequences of actions minutes into the future. And to do that, you actually much more of an abstracted semantic model of the world.[00:07:32] The Bitter Lesson & Data Abstraction[00:07:32] swyx: Yeah, the question comes where you want to have more structure than is available in just predicting the next token.[00:07:41] And typically, well, let’s, let’s call it the experience of the last five years has been that is just washed away by scale, right? So what is the right middle ground here that, you don’t ignore the bitter lesson, but also you. Can be more efficient than what we’re doing today.[00:07:57] Chris Manning: One possibility [00:08:00] is, look, if we just collect masses and masses and masses and masses of video data, this problem will be solved.[00:08:11] Under certain assumptions that could be true, but there are sort of multiple avenues in which it could not be true. The first is what’s really essential is understanding the, the consequences of actions producing an action conditioned world model. And if you are simply, collecting observational video data, which is the easy stuff to collect, when you’re sort of mining online videos, you don’t actually.[00:08:41] Know the actions that are being taken to see how the video is changing. And so if you are never collecting directly actions and you are having to try and infer them from what happened in the observed video, that’s not impossible. But it’s very [00:09:00] hard and it’s not really established that you can get that to work at any scale yet.[00:09:05] And so there’s a lot of premium on collecting action condition video data, which is part of why there’s been a lot of interest in using simulation so that you can be collecting data where you do know the actions, which isn’t quite limited supply, but there’s also in the limit of as much data as you could possibly have.[00:09:28] Maybe the problem is eventually solvable, but. Even though we collect huge amounts of text data is always at a great level of abstraction, right? Language is a human designed, abstracted representation where there’s meaning in each token and it’s representing and abstraction of the world, right?[00:09:51] As soon as you are describing someone as a professor, and as soon as you are saying that they’re condescending, right? These are very [00:10:00] abstracted descriptions of the world. It’s not at what you’re observing as pixel level, and to get to that kind of degree of abstraction, starting from pixels is orders and magnitude of extra data and processing.[00:10:14] And so, although, we absolutely want to exploit, get as much data as possible, use the bitter lesson. Nevertheless, if there are ways in which you can work with five orders of magnitude less data than people working purely from pixels, you’re gonna be able to make a lot more progress, a lot more quickly.[00:10:34] And that’s the bet here. And so you could just say that’s only wanting to be able to, do it more efficiently, do it more quickly, do it more cheaply. But I think it’s actually more than that, I think. One should be making the analogy to how human beings work at one level. You know? Yes, we have these high [00:11:00] resolution eyes and we can look and see a scene like a video, but all of the evidence from neuroscience and psychology is that most of what comes into people’s eyes is never processed.[00:11:13] Right. That you are doing fairly fine ated processing of exactly what you’re focusing on. But as soon as it’s away from that of yeah, there’s another guy over there that you’ve sort of only processing top down this very abstracted semantic description of the world around you. And so, that’s what human beings are doing.[00:11:33] They’re working with semantic abstractions and so. I think it is just the right representation. ‘cause we also have other goals we want to be able to do, real time worlds. So that means there’s a limit to ho…

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    Mistral: Voxtral TTS, Forge, Leanstral, & what's next for Mistral 4 — w/ Pavan Kumar Reddy & Guillaume Lample Mar 30, 2026
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    Mistral has been on an absolute tear - with frequent successful model launches it is easy to forget that they raised the largest European AI round in history last year. We were long overdue for a Mistral episode, and we were very fortunate to work with Sophia and Howard to catch up with Pavan (Voxtral lead) and Guillaume (Chief Scientist, Co-founder) on the occasion of this week’s Voxtral TTS launch:Mistral can’t directly say it, but the benchmarks do imply, that this is basically an open-weights ElevenLabs-level TTS model (Technically, it is a 4B Ministral based multilingual low-latency TTS open weights model that has a 68.4% win rate vs ElevenLabs Flash v2.5). The contributions are not just in the open weights but also in open research: We also spend a decent amount of the pod talking about their architecture that combines auto-regressive generation of semantic speech tokens with flow-matching for acoustic tokens (typically only applied in the Image Generation space, as seen in the Flow Matching NeurIPS workshop from the principal authors that we reference in the pod).You can catch up on the paper here and the full episode is live on youtube!Timestamps00:00 Welcome and Guests00:22 Announcing Voxtral TTS01:41 Architecture and Codec02:53 Understanding vs Generation05:39 Flow Matching for Audio07:27 Real Time Voice Agents13:40 Efficiency and Model Strategy14:53 Voice Agents Vision17:56 Enterprise Deployment and Privacy23:39 Fine Tuning and Personalization25:22 Enterprise Voice Personalization26:09 Long-Form Speech Models26:58 Real-Time Encoder Advances27:45 Scaling Context for TTS28:53 What Makes Small Models30:37 Merging Modalities Tradeoffs33:05 Open Source Mission35:51 Lean and Formal Proofs38:40 Reasoning Transfer and Agents40:25 Next Frontiers in Training42:20 Hiring and AI for Science44:19 Forward Deployed Engineering46:22 Customer Feedback Loop48:29 Wrap Up and ThanksTranscriptswyx: Okay, welcome to Latent Space. We’re here in the studio with our gues co-host Vibh u. Welcome. Thanks. Excited for this one as well as Guillaume and Pavan from Mistral. Welcome. Excited to be here.Guillaume: Thank you.swyx: Pavan, you are leading audio research at Mistral and Guillaume, you're Chief Scientist,Announcing Voxtral TTSswyxHost(00:05) Okay. (00:05) Welcome to Lean Space. (00:06) We’re here in the studio with trustee co-hosts, Vibhu. (00:09) Welcome.VibhuHost(00:11) Very excited for this one.swyxHost(00:12) As well as Guillaume and Pavan from Mistral. (00:15) Welcome. (00:16) Excited to be here. (00:17) Thank you for having us.(00:18) Pavan, you are leading audio research at Mistral and Guillaume, you’re a chief scientist. (00:23) What are we announcing today where we’re coordinating this release with you guys?GuillaumeGuest(00:26) Yeah, so we are releasing Voxtral TTS. So it’s our first audio model that generates speech. It’s not our first audio model. We had a couple of releases before.(00:35) We had one in the summer that was Voxtral, our first audio model, but it was like a transcription model, ASR. Like a few months later, we released some update on top of this, supporting more languages. Also a lot of table stack features for our customers, context biasing, precision, timestamping and transcription. We also have some real-time model that can transcribe not just at the end of the level.(00:56) You don’t need to fill your entire audio file, but that can also come in real-time. And here, this is a natural extension in the audio, so basically speech generation. So yeah, so we support nine languages, and this is a pretty small model, 3D model, so very fast, and also state of the art. Performed at the same level as the base model, but it’s much more efficient in terms of cost, and also much, in terms of cost, it’s also much cheaper, only a fraction of the cost of our competitors.(01:22) And we are also releasing the work that this model is running.swyx What’s the decision factor?Guillaume It’s a good question.swyxThere will be more. Yeah, Pavan, any sort of research notes to add on?Architecture and CodecPavan: But it’s a novel architecture that we develop inhouse.We traded on several internal architectures and ended up with a auto aggressive flow matching architecture. And also have a new in-house neural audio codec. Which, converts this audio into all point by herds latent [00:02:00] tokens, semantic and acoustic tokens. And yeah, that’s that’s their new part about this model and we’re pretty excited that it’s, it came out with such good quality and Jim was mentioning. Yeah, it’s a three B model. It’s based off of the TAL model that we actually released just a few months back and insert trunk and mainly meant for like the TTS stuff, but they need text capabilities are also there. Yeah.swyx: So there’s a lot to cover.I always I love any, anything to do with novel encodings and all those things because I think that’s obviously I creates a lot of efficiency, but also maybe bugs that sometimes happen. You were previously a Gemini and you worked on post training for language models, and maybe a lot of people will have less experience with audio models just in general compared to pure language.What did you find that you have to revisit from scratch as you joined this trial and started doing this? At leastUnderstanding vs GenerationPavan: when it comes to, for, I think the, there are two buckets, I guess the audio understanding and audio [00:03:00] generation. The audio understanding, like the walkthrough models that Kim was mentioning that we released earlier.The walkthrough chat that we released I think July last year, and the follow up transcription only, models family that we released in January, that would be one bucket, and the generation is another bucket. I think. You can also treat them as a unified set of models, but currently the approaches are a little different between these two.To your question on how audio is fed to the model? In the understanding model, it’s very similar to actually Pixar models that we also released,swyx: yes.Pavan: That’sswyx: amazing.Pavan: It was pretty, I, that was the first project I worked on after joined Misra. It was pretty, pretty nice. And Wtu was very similar in spirit.I guess So we feed audio through an audio encoder similar to images through a vision encoder, and it produces continuous embeddings and which are fed as tokens to the main transformer decoded transformer model. Yeah. On the model output is just text. So on the output side, there is nothing that needs to be done in these kinds of mode.I [00:04:00] guess the interesting part of what the generation stuff is, the output now has to produce audio and. The approach that we have is this neural audio codec, which converts audio into these latent tokens. There is a lot of existing attrition and a lot of models which are based off of this kind of approach.And we took a slightly. A different, design decisions around this. But at the end of the day, the neural audio product converts audio into a 12.5 herdz set of latents. And each latent is, has a semantic token and a set of acoustic tokens. And the idea is that you take these discrete tokens and then feed it on the input side.There’s several ways to use this at each frame, but we just sum the embedding. So it’s like having key different vocabularies. Combine all of them because they all correspond to one audio frame on the input side. The output side is the interesting part on the output side, the, it’s not the, I don’t know if it’s the most popular, but one.Popular technique is to have a depth transformer [00:05:00] because you have K tokens at each time step, like with a text, you just have one token at each time step. So you just do predict the token from the vocabulary with, yeah, with just, you get probabilityswyx: This’s a very straightforward text. VeryPavan: straightforward.swyx: Yeah.Pavan: But if you have K tokens, then the name thing would be to predict all of them in paddle. That doesn’t work. At least that doesn’t work that well because audio has more entropy. And the, one of the techniques people use is this depth transformer where you you almost have a small transformer, or it can be L-S-T-M-R in as well, but people use transformers and you predict the K tokens in auto aggressive fashion in that.So you have two auto reive things going on.Flow Matching for AudioPavan: So the thing we did differently is in, instead of having this auto aggressive K step prediction, we have a flow matching model. Instead of modeling this as a discrete token set we trained the codec to be both discrete and continuous to have this flexibility.So we did try the discrete stuff too, and which it works well, but the continuous stuff works just better. So yeah, we took this flow matching, so the, it’s a flow [00:06:00] matching head, which takes the latent from the main transformer and like kind in fusion, it’s denoising, but in this flow matching itself, velocity estimate.So you go from this noise t all the way to there. Audio latent, which corresponds to the 80 millisecond audio and then, which is sent through the work order to get back the 80 millisecond audio frame.swyx: Yeah. Is this the first application of flow matching in audio? Because usually I come across this in the image.Pavan: Yeah. Actually, in some sense there are models flow matching models in audio, but I think this specific combination I could be wrong. There could be somewhat. No. I haven’t seen. I haven’t seen much work in this, so I think it’s novel and a lot of it’s just a way bigger community, so they, I think they pioneer a lot of these diffusion flow matching work, and it’s interesting to adopt some of the ideas there into audio and,swyx: yeah.Pavan: Yeah, I’m, personally that’s the think part which is trying out about. One of more meta point is unlike text, even in vision, I think this is true, but in [00:07:00] audio step literature that there is no.Winner model, yet there is no, okay, this is the way you do things. It’s it’s still by, I think people are still iterating and figuring out like what’s the best overall recipe. I guess the idea. Pretty sure there are models which are also completely end-to-end, like NATO audio. NATO audio, but it’s still not come to a convergence point where this, the right way to think that.That also makes. A space pretty exciting to explore.Real Time Voice AgentsVibhu: What are some of the ways to look at it?Vibhu: There are ways where you can do diffusion for audio generation, but if you want like real time generation, that’s a big thing with the approach I’m assuming that you took. Yeah. And also like how do you go about evaluating different axes of what you care about, yeah,Pavan: good point. I think we so you can do just flow matching diffusion for the whole audio. We didn’t even go down that path because one of the main applications is voice agents and we want real time streaming, and that’s the use case. That’s not the only use case, but that’s one of the primary use cases we want to get to.So we [00:08:00] picked the auto aggressive approach for that. And within the auto aggressive space, again, you can do chunk by chunk or you can do so we picked the. I think at least personally prefer the operations, which are the simplest, and so we try to see, can we just add audio as just another head to our regular transformer decode model because that kind of makes it easier for eventual end-to-end modeling of audio text native modeling.Yeah. And it works pretty well. So I guess we went with that and we tried a little bit, but the flow matching head itself, like we had a discreet. Diffusion kind of approach, which also works well, but the flow matching work better.swyx: I was just curious about how you also think about this overall direction of research.Do you basically, when you work with the audio team, do you set some high level parameters and then let them explore whatever, or how does it work between you guys?Guillaume: No I think the way it works is that we are the, we are prioritizing together, I think, what are the most important features because there are many things we can do [00:09:00] in audio.Yeah, I think we try to. These are like how we should do things, for instance. Ultimately what we want to do is to build this through duplex model, but we are not going to start this start there directly, I think is. Some of the project people are doing, butswyx: just to confirm, full effects means it can speak while I’m speaking or,Guillaume: yeah.Okay. Audio. Yeah. Yeah. So intimately we’re going to get there, but for us it was, we decided to take it like a step by step. So we start with whatever is the most important. I think support customers, which is the transcription is the most popular use case. Then the speech generation, Soviet time, just a bit before that.And then actually to be like more, but try combining everything all together. But but yeah, we thought it was also important to like separate things and optimize each capability one by one before weswyx: measure of that together. And the super omni model. ButGuillaume: very interesting because as Par said, it’s when you work on some other domains of this airline and everything, there are many areas where I think it’s not as interesting.For instance. Many places, it’s essentially just around data or like creating new environments on a lot of kind [00:10:00] of easy things. But things were, I think the research is maybe not as interesting. Were in audio. There are so many ways to actually build this model. So many ways to go around it. That’s the sense I think is really interesting.And what we also tried for speed generation is that we tried multiple approaches. What was interesting that even though they were extremely different, they under the big know the particles but the for matching turned out to be quite more natural. So we are happy with this.swyx: Is there intuition why it maybe like flow matching is just models speech better in some natural fundamental, latent dimension?Pavan: No, I think the main thing is e even at a particular time step, there is a distribution of things.swyx: Yes.Pavan: To be predicted like the way you inflate. So you already know the word that you’re speaking and Yeah. The intake space, let’s say the word maps register a single token for simplicity.In most cases it does. So there is not a lot of so you just pick the word, but with within audio, even the same word could, even with your own voice, could be inflicted in so many different ways. And I think [00:11:00] any approach which like models this distribution and. And flow matching is one, one of the take.It’s not the only one at all, but it’s a one which works pretty reasonably well. I think that’s better. So you have to pick across several different, the intuition I have is it’s, there are some, several different clusters each corresponding to some specific way you would inflict, pronounce that thing.And you can’t predict the mean of it because that corresponds to some blurred out speech or something like that. But you have to pick one. And then like sharpswyx: conditional inference.Pavan: Yeah, exactly.swyx: Is that all covered under disfluencies, which is I think the normal term of art. Pauses intonations. By the way, I have to thank Sophia for setting all this up, including like some of these really good notes becausePavan: Yeah.swyx: I’m less familiar with the audios for me.Pavan: No. I think dis dismisses are definitely one such Eno defenses is more likeswyx: which is arms are.Pavan: Yeah, arms. And also repeat like you like,swyx: yeah.Pavan: You do this full of words, your thinking, so you repeat the word.swyx: Okay. Whereas intonation is like a diff, it’s up up [00:12:00] speak and all this.Okay.Pavan: Yeah. So I think there is a lot of like entropy. And modeling it as a distribution. And a, any technique which helps with it and the depth transformer is a conditional way of modeling this. And Transformers a…

    Full show notes at the publisher

    🔬Why There Is No "AlphaFold for Materials" — AI for Materials Discovery with Heather Kulik Mar 24, 2026
    Show notes

    Materials science is the unsung hero of the science world. Behind every physical product you interact was decades of research into getting the properties of materials just right. Your gym clothes contain synthetic fibers developed over decades. The glass screen, diodes, and chip substrate technology needed to read this blog post were only viable due to many teams of material scientists.

    Our guest Prof. Heather Kulik was one of the first material scientists to realize that there was alpha in combining computational tools with data driven modeling — she did AI for science before it was cool. She has a hard-fought perspective for how to succeed in this field. Yes, she believes the wins are real. To get there you must work hard to deeply integrate domain expertise with AI techniques, and also maintain a discriminating mind. Ultimately what matters is you succeed in the lab, and nature doesn’t care about how hyped a model is. These lessons personally resonated with the Latent.Space Science team and our own experience.

    This episode is a must watch for all aspiring AI for science practitioners. A few highlights:

    Designing new polymers with AI: Heather’s group recently used AI to design new polymers that are significantly stronger. These materials were created and tested in the lab, and the scientists who built them were surprised by the designs. The AI had figured out certain building blocks could break in a novel way. The AI discovered a purely quantum mechanical effect, and after convincing their lab collaborators to actually synthesize it, the material turned out to be four times tougher!

    The twenty-two-atom ligand challenge: When asked about the role and need of human scientists, Heather points out that AI has a strong understanding of academic chemistry, but is still lacking intuition. Every time an LLM is updated, Heather asks it to design a ligand that contains exactly twenty-two heavy atoms. She has yet to find one that can succeed at this seemingly simple task that any expert could do in a second! Is this the chemistry counterpart to counting ‘r’s in strawberry?

    Side note: Heather joked that this comment would date itself immediately, so we decided to see if this was still true three months after recording. We found some interesting results! We asked both Claude and ChatGPT to design a 22 atom ligand for both a metal-organic framework (MOF) and a Kinase protein.

    * For the Kinase, both models got it right: Claude pulled out RDKit in a python script and iterated on several designs, whereas ChatGPT just one-shotted it.

    * For MOFs, both models got it wrong, generating ligands with 21, 23, or 24 atoms, yet stubbornly not getting 22 atoms.

    Is there something different about how LLMs reason in the materials and bio domains?

    Materials vs biology: The two biggest domains of AI in science have been biology and materials. We asked Heather if there could be an AlphaFold moment for materials. Her answer reframes how we should think about the field:

    * First, the datasets in material science are woefully lacking in comparison to the bio world. The closest to ground truth in most cases are noisy DFT datasets. These are just approximations to the real world! The datasets that are accurate are all boring, as Heather quipped “We have really good datasets for really boring chemistry.” Furthermore, good experimental structures are hard to come by and require interpretation. So generating generating high-quality, novel datasets at scale would really drive the field forward.

    * More philosophically, AlphaFold is making predictions in a fairly limited space: there are just twenty amino acids. Sure, even here AlphaFold doesn’t get everything right, but it seems plausible that one could learn the entire design space. For materials, each element is a new set of interactions and chemistry, with little to no transferability. This is a massive open problem in material science that we hope some of the smartest AI scientists will want to work on!

    The difficulties of trusting the literature: Heather’s team has spent the last few years using NLP and later LLMs to extract data from literature. Even a few thousand data points from these papers can be valuable for guiding her group’s work. One surprising result: sometimes the reported values for a property (say temperature) do not match up with the graphs in the papers! So there’s lots of potential in using LLMs to mine data from the literature, just do it with care.

    The role of academia in an ever-changing world: One theme that has been running through many of our conversations has been the changing role of the academic — and the scientist — in science. When startups are raising $100s of millions and hyperscalers and Big Pharma are all ramping up AI-for-science efforts, the academic researcher needs both resources and judgement about problems to chase more than ever.

    Resources include data that is organized for machine learning, access to high throughput experimentation labs, and compute resources. These are all things that academics can build together. More importantly, Heather emphasizes curiosity about problems that haven’t hit the radar of the heavily capitalized AI companies. After so many years on the forefront of AI for Science, Heather’s judgement that Chemical Engineering and Material Science still need curious people asking questions with no clear path to money is a welcome beacon in the AI fog.

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