Journal of Clinical Oncology (JCO) Podcast

Latest Episodes:

HERA Indicates that Adjuvant Trastuzumab Confers Equal Benefit for HER2-Positive Invasive Ductal and Invasive Lobular Breast Cancers Apr 15, 2013

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This Podcast reviews the results of the analysis conducted by Metzger-Filho et al. regarding the benefit of trastuzumab for patients with invasive lobular breast cancer treated on the Herceptin Adjuvant Trial (HERA) and provides perspective regarding the clinical significance of these findings.

New Evidence of the Clinical Significance of Cigarette Smoking by Colon Cancer Patients Apr 01, 2013

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This podcast summarizes findings regarding cigarette smoking and disease-free survival in a Phase III adjuvant colon cancer trial.

Radiotherapy for Pediatric Hodgkin Lymphoma: Are We Ready To Say Goodbye? Mar 18, 2013

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Response after early chemotherapy cycles might identify patients who could safely forgo consolidation with radiotherapy.

Minimal-Intensity Conditioning: A Decade Later Mar 11, 2013

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This podcast reflects on the outcome of minimal intensity conditioning in over 1000 recipients of sibling and unrelated donor transplant.

Evolution of Concurrent Chemoradiation Treatment Approaches in Head and Neck Cancer Mar 05, 2013

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This podcast provides commentary and observations on the long term results summary of RTOG 91-11 in which concurrent chemoradiation was shown to provide superior outcome over induction chemotherapy or radiation alone to achieve larynx preservation and locoregional tumor control.

Off-Label Cancer Therapy Use: How Much is Too Much? Feb 19, 2013

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This podcast reviews findings on the prevalence of off-label cancer therapy use and the estimated costs associated with it.

Caring For Patients With Transformed Follicular Lymphoma Feb 12, 2013

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If transplantation is selected as the treatment approach, the net effect is likely to be similar with allogeneic or autologous transplantation with the higher early mortality rate in the allogeneic patients offset by a higher relapse rate in the autologous patients.

Outpatient Therapy for Fever and Neutropenia is Safe But Implementation is the Key Jan 28, 2013

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The fluoroquinolone class of antibiotics is a major target for antimicrobial stewardship programs, and the conservation of their effectiveness is important.

Outcomes in Cancer Survivors Who Develop Second Malignant Neoplasms Jan 22, 2013

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This podcast provides perspective on findings in a large population-based evaluation of overall survival and cancer-specific survival in patients with CLL who develop a second primary cancer.

Molecular Profiling of Gastric Cancer: Toward Personalized Cancer Medicine Jan 22, 2013

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One third of gastric cancers harbor genetic or epigenetic alterations in the CDH1 gene, and those with structural changes have a poorer prognosis; gastric tumor profiling for oncogenic amplifications and mutations may identify targets for personalized therapeutics.