JACC Specialty Journals

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Myocarditis: A Rare Cardiac Manifestation of Antiphospholipid Syndrome | JACC: Case Reports | ACC.25 Mar 27, 2025

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Mary Norine Walsh, MD, MACC, JACC: Case Reports Deputy Editor, is joined by author Alexander C Sacher, DO, discussing this study from Sacher et al presented at ACC.25 and published in JACC: Case Reports. Antiphospholipid syndrome (APS) is known for thrombotic events and pregnancy complications, but its association with myocarditis is rare and poorly understood. In this case, a 44-year-old female presented with acute chest tightness, elevated cardiac biomarkers, and severe anemia. Diagnostic workup revealed ST-segment changes on ECG, preserved left ventricular function on echocardiography, and myocardial inflammation on cardiac MRI, suggestive of acute myocarditis. Positive antiphospholipid antibodies confirmed APS. She was managed with close multidisciplinary follow up. This case highlights the role of cardiac MRI in diagnosing myocarditis early, guiding management strategies, and the need for heightened clinical suspicion in APS patients presenting with cardiac symptoms.

Symptomatic Tricuspid Valve Obstruction due to IVL | JACC: Case Reports | ACC.25 Mar 27, 2025

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Miho Fukui, MD, JACC: Case Reports Associate Editor, is joined by author Ree Lu, MD, discussing this study from Cho et al presented at ACC.25 and published in JACC: Case Reports. Intravenous leiomyomatosis (IVL) is a rare benign uterine growth that extends into the venous system. This case describes a 48-year-old female who presented with 1 month of chest pain and dyspnea on exertion. She was found to have a right atrial mass that transiently crossed into the right ventricle with associated moderate tricuspid regurgitation. Computed tomography revealed a uterine mass with contiguous intravascular extension through the inferior vena cava terminating in the right atrium. This case of symptomatic tricuspid valve obstruction due to IVL illustrates the importance of maintaining preload. Chest and abdominal imaging may be necessary to identify the source of the mass and ensure appropriate surgical planning.

Transcatheter Mechanical Aspiration of Right Ventricle Lead Vegetation | JACC: Case Reports | ACC.25 Mar 27, 2025

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Maurice Enriquez-Sarano, MD, FACC JACC: Case Reports Associate Editor, is joined by author Emmanuel Daniel, MD, discussing this study from Daniel et al presented at ACC.25 and published in JACC: Case Reports. Large lead-associated vegetations carry a significant risk of pulmonary embolism with hemodynamic instability when transvenous lead extraction is attempted. In this case, a 54-year-old male came to the hospital with fever and dyspnea. He was found to have MSSA bacteremia and a large RV lead vegetation on echo. He had multiple co-morbidities and was a high-risk surgical candidate. He underwent successful vegetation aspiration using the Flowtriever system, followed by endovascular lead extraction.

Significance of Coronary Artery Calcifications and Ischemic Electrocardiographic Changes Among Patients Undergoing Myocardial Perfusion Imaging | JACC: Advances Mar 26, 2025

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Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Significance of Coronary Artery Calcifications and Ischemic Electrocardiographic Changes Among Patients Undergoing Myocardial Perfusion Imaging

Sodium-Glucose Cotransporter-2 Inhibitors and Arrhythmias: A Meta-Analysis of 38 Randomized Controlled Trials | JACC: Advances Mar 26, 2025

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Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Sodium-Glucose Cotransporter-2 Inhibitors and Arrhythmias: A Meta-Analysis of 38 Randomized Controlled Trials

Social Determinants of Health and 30-Day Readmission After Acute Myocardial Infarction in the REGARDS Study | JACC: Advances Mar 26, 2025

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Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Social Determinants of Health and 30-Day Readmission After Acute Myocardial Infarction in the REGARDS Study

Management of Rhythm and Conduction Disorders in Cardiac Amyloidosis: A French Nationwide Delphi Study | JACC: Advances Mar 26, 2025

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Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Management of Rhythm and Conduction Disorders in Cardiac Amyloidosis: A French Nationwide Delphi Study

Identifying Patterns of Tobacco Use and Associated Cardiovascular Disease Risk Through Machine Learning Analysis of Urine Biomarkers | JACC: Advances Mar 26, 2025

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Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Identifying Patterns of Tobacco Use and Associated Cardiovascular Disease Risk Through Machine Learning Analysis of Urine Biomarkers

Safety and Efficacy of Different Stent Strategies in Percutaneous Coronary Intervention: A Network Meta-Analysis | JACC: Advances Mar 26, 2025

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Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Safety and Efficacy of Different Stent Strategies in Percutaneous Coronary Intervention: A Network Meta-Analysis

Association of Hemoglobin A1c Levels With All-Cause Mortality in Patients With Coronary Artery Disease: The Essen Coronary Artery Disease Registry | JACC: Advances Mar 26, 2025

Show notes

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Association of Hemoglobin A1c Levels With All-Cause Mortality in Patients With Coronary Artery Disease: The Essen Coronary Artery Disease Registry

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