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    Health & Fitness

    JACC Specialty Journals

    In this podcast series, editors-in-chief from the JACC family of specialty journals provide highlights and summarize key findings for select issues. Published by the American College of Cardiology, the JACC Journals publish peer-reviewed articles on all aspects of cardiovascular disease, including original clinical studies, translational investigations with clear clinical relevance, state-of-the art papers, and review articles. They are top ranked for impact factor and their manuscripts are among the most covered by media outlets, most talked about on social media, and most read online.

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    Latest Episodes:
    Coronary Sinus Reduction for REDUCER-I Patients With Refractory Angina and Angiographically Nonobstructive Coronary Artery Disease | JACC: Advances Apr 22, 2026
    Show notes

    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Coronary Sinus Reduction for REDUCER-I Patients With Refractory Angina and Angiographically Nonobstructive Coronary Artery Disease.

    Remote Management of Patients With Heart Failure in Medically Underserved Areas | JACC: Advances Apr 22, 2026
    Show notes

    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Remote Management of Patients With Heart Failure in Medically Underserved Areas.

    Development of a Predictive Tool in Patients With High Pretest Probability for Transthyretin Amyloid Cardiomyopathy | JACC: Advances Apr 22, 2026
    Show notes

    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Development of a Predictive Tool in Patients With High Pretest Probability for Transthyretin Amyloid Cardiomyopathy.

    Valvular Heart Diseases in Swedish Males and Females: A National Cohort Study | JACC: Advances Apr 22, 2026
    Show notes

    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Valvular Heart Diseases in Swedish Males and Females: A National Cohort Study.

    Cardiovascular-Kidney-Metabolic Syndrome and Life Expectancy in U.S. Adults | JACC: Advances Apr 22, 2026
    Show notes

    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Cardiovascular-Kidney-Metabolic Syndrome and Life Expectancy in U.S. Adults.

    10-Year Excess Mortality After First-Time Non–ST-Segment Elevation Myocardial Infarction: The Western Denmark Heart Registry | JACC: Advances | JACC: Advances Apr 22, 2026
    Show notes

    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on 10-Year Excess Mortality After First-Time Non–ST-Segment Elevation Myocardial Infarction: The Western Denmark Heart Registry.

    Cardiac Biomarker Complete Response in AL Amyloidosis | JACC: CardioOncology Apr 21, 2026
    Show notes

    Dr. Michel G. Khouri reviews a landmark study examining patients with AL amyloidosis who achieved a complete cardiac biomarker response, highlighting profound improvements in cardiac structure, function, and long-term survival that rival the general population. The discussion underscores the transformative impact of early diagnosis and modern plasma cell–directed therapies, while reminding clinicians that ongoing multidisciplinary cardiac care remains essential even after sustained cardiac remission.

    Cardiovascular Adverse Events Associated with Bispecific T-cell Engager Therapy | JACC: CardioOncology Apr 21, 2026
    Show notes

    Dr. Qun Shao discusses two multicenter studies evaluating cardiovascular adverse events associated with bispecific T‑cell engager therapies. Drawing on data from over 700 patients, the episode highlights the incidence, predictors, and clinical impact of cardiovascular complications, emphasizing the importance of baseline risk assessment, targeted monitoring, and multidisciplinary management as use of these therapies continues to expand.

    Myocardial Expression of PD-L1 as a Marker of Poor Prognosis in Immune Checkpoint Inhibitor–Associated Myocarditis | JACC: CardioOncology Apr 21, 2026
    Show notes

    Research fellow, Adrian Chen, discusses a multicenter study evaluating myocardial PD‑L1 expression as a prognostic biomarker in immune checkpoint inhibitor–associated myocarditis. The conversation highlights how elevated myocardial PD‑L1 identifies patients at markedly higher risk for early adverse cardiac events and explores its potential role in improving risk stratification and guiding earlier, more aggressive therapy in this high‑risk population.

    June 2026 Issue Summary | JACC: CardioOncology Apr 21, 2026
    Show notes

    Dr. Ky's full issue summary.

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